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Erschienen in:
28.11.2015 | Correspondence
Occurrence of Double Monoclonal Bands on Protein Electrophoresis: An Unusual Finding
Erschienen in: Indian Journal of Hematology and Blood Transfusion | Sonderheft 1/2016
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Various techniques of protein electrophoresis are used for detection of monoclonal proteins/paraproteins in serum and/or urine of patients with monoclonal gammopathies. These are detected as the so-called ‘M’ bands (monoclonal bands) on serum protein electrophoresis and/or immunofixation electrophoresis. In most cases, a single M-band is detected. However, more than one M-band can be detected in the samples of a minor proportion of patients. This condition is termed as ‘double gammopathy’ or ‘biclonal gammopathy’. A knowledge of such an unusual occurrence is essential for recognition and appropriate interpretation of this entity.