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Erschienen in: Breast Cancer Research 5/2003

01.10.2003 | Review

Oestrogen exposure and breast cancer risk

verfasst von: Ruth C Travis, Timothy J Key

Erschienen in: Breast Cancer Research | Ausgabe 5/2003

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Abstract

Epidemiological and experimental evidence implicates oestrogens in the aetiology of breast cancer. Most established risk factors for breast cancer in humans probably act through hormone-related pathways, and increased concentrations of circulating oestrogens have been found to be strongly associated with increased risk for breast cancer in postmenopausal women. This article explores the evidence for the hypothesis that oestrogen exposure is a major determinant of risk for breast cancer. We review recent data on oestrogens and breast cancer risk, consider oestrogen-related risk factors and examine possible mechanisms that might account for the effects of oestrogen. Finally, we discuss how these advances might influence strategies for reducing the incidence of breast cancer.
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Metadaten
Titel
Oestrogen exposure and breast cancer risk
verfasst von
Ruth C Travis
Timothy J Key
Publikationsdatum
01.10.2003
Verlag
BioMed Central
Erschienen in
Breast Cancer Research / Ausgabe 5/2003
Elektronische ISSN: 1465-542X
DOI
https://doi.org/10.1186/bcr628

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