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Erschienen in: Journal of Neuro-Oncology 2/2010

01.11.2010 | Case Report

Olfactory ensheathing cell tumour: case report and literature review

verfasst von: Ioana Darie, Laurent Riffaud, Stéphan Saïkali, Gilles Brassier, Abderrahmane Hamlat

Erschienen in: Journal of Neuro-Oncology | Ausgabe 2/2010

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Abstract

Olfactory ensheathing cell tumour (OECT) and olfactory groove schwannoma (OGS) are among the rarest intracranial tumour types that develop within anterior cranial fossa. These tumours share several similarities, including radiological and histological aspects, and only immunohistochemical staining can differentiate between them. We report a case of OECT occurring in a 28-year-old woman with a history of complex partial seizures, emotional lability and anosmia. Radiological features showed a predominantly left subfrontal extra-axial mass. Total excision of the tumour, connected to the cribriform plate and contiguous to the left olfactory bulb, was performed. Histological examination suggested an atypical schwannoma; however, immunohistochemical staining was strongly positive for S-100 protein but negative for both epithelial membrane antigen (EMA) and CD 57 (Leu-7). The final diagnosis was olfactory ensheathing cell tumour. We describe the third case of OECT and emphasize the important role of immunohistochemical staining in diagnosis: awareness of this entity, and use of immunohistochemistry help to distinguish it from OGS.
Literatur
1.
Zurück zum Zitat Ippili K, Ratnam BG, Gowrishankar S, Ranjan A, Lath R (2009) Olfactory ensheathing cell tumor. Neurol India 57:76–78CrossRefPubMed Ippili K, Ratnam BG, Gowrishankar S, Ranjan A, Lath R (2009) Olfactory ensheathing cell tumor. Neurol India 57:76–78CrossRefPubMed
2.
Zurück zum Zitat Yasuda M, Higuchi O, Takano S, Matsumura A (2006) Olfactory ensheathing cell tumor: a case report. J Neurooncol 76:111–113CrossRefPubMed Yasuda M, Higuchi O, Takano S, Matsumura A (2006) Olfactory ensheathing cell tumor: a case report. J Neurooncol 76:111–113CrossRefPubMed
3.
Zurück zum Zitat Bezircioglu H, Sucu HK, Rezanko T, Minoglu M (2008) Nasal-subfrontal giant schwannoma. Turk Neurosurg 18:412–414PubMed Bezircioglu H, Sucu HK, Rezanko T, Minoglu M (2008) Nasal-subfrontal giant schwannoma. Turk Neurosurg 18:412–414PubMed
4.
Zurück zum Zitat Adachi K, Yoshida K, Miwa T, Ikeda E, Kawase T (2007) Olfactory schwannoma. Acta Neurochir (Wien) 149:605–611CrossRef Adachi K, Yoshida K, Miwa T, Ikeda E, Kawase T (2007) Olfactory schwannoma. Acta Neurochir (Wien) 149:605–611CrossRef
5.
Zurück zum Zitat Carron JD, Singh RVP, Karakla DW, Silverberg M (2002) Solitary schwannoma of the olfactory groove: case report and review of the literature. Skull Base 12:163–166CrossRefPubMed Carron JD, Singh RVP, Karakla DW, Silverberg M (2002) Solitary schwannoma of the olfactory groove: case report and review of the literature. Skull Base 12:163–166CrossRefPubMed
6.
Zurück zum Zitat Choi YS, Sung KS, Song YJ, Kim HD (2009) Olfactory schwannoma—case report. J Korean Neurosurg Soc 45:103–106CrossRefPubMed Choi YS, Sung KS, Song YJ, Kim HD (2009) Olfactory schwannoma—case report. J Korean Neurosurg Soc 45:103–106CrossRefPubMed
7.
Zurück zum Zitat Daglioglu E, Okay O, Dalgic A, Albayrak AL, Ergungor F (2008) Cystic olfactory schwannoma of the anterior cranial base. Br J Neurosurg 22:697–699CrossRefPubMed Daglioglu E, Okay O, Dalgic A, Albayrak AL, Ergungor F (2008) Cystic olfactory schwannoma of the anterior cranial base. Br J Neurosurg 22:697–699CrossRefPubMed
8.
Zurück zum Zitat Erdem Y, Bayar MA, Ozturk K, Caydere M (2004) Intracranial subfrontal schawannoma. Turk Neurosurg 14:80–83 Erdem Y, Bayar MA, Ozturk K, Caydere M (2004) Intracranial subfrontal schawannoma. Turk Neurosurg 14:80–83
9.
Zurück zum Zitat Kanaan H, Gardner PA, Yeaney G, Prevedello DM, Monaco EA III, Murdoch G, Pollack IF, Kassam AB (2008) Expanded endoscopic endonasal resection of an olfactory schwannoma. J Neurosurg Pediatr 2:261–265CrossRefPubMed Kanaan H, Gardner PA, Yeaney G, Prevedello DM, Monaco EA III, Murdoch G, Pollack IF, Kassam AB (2008) Expanded endoscopic endonasal resection of an olfactory schwannoma. J Neurosurg Pediatr 2:261–265CrossRefPubMed
10.
Zurück zum Zitat Martinez-Soto L, Alfaro-Baca R, Torecilla-Sardon MV, Fernandez-Vallejo B, Ferreira-Munoz R, De Diego T (2009) Un nuevo caso de «schwannoma del olfatorio»: presentacion y revision de la literatura. Neurocirugia (Astur) 20:294–297 (in Spanish) Martinez-Soto L, Alfaro-Baca R, Torecilla-Sardon MV, Fernandez-Vallejo B, Ferreira-Munoz R, De Diego T (2009) Un nuevo caso de «schwannoma del olfatorio»: presentacion y revision de la literatura. Neurocirugia (Astur) 20:294–297 (in Spanish)
11.
Zurück zum Zitat Prak JH, Kim TY, Park JT, Kim JM (2006) Olfactory groove schwannoma. J Korean Neurosurg Soc 39:156–158 Prak JH, Kim TY, Park JT, Kim JM (2006) Olfactory groove schwannoma. J Korean Neurosurg Soc 39:156–158
12.
Zurück zum Zitat Prasad D, Jalali R, Shet T (2004) Intracranial subfrontal schwannoma treated with surgery and 3D conformal radiotherapy. Neurol India 52:248–250PubMed Prasad D, Jalali R, Shet T (2004) Intracranial subfrontal schwannoma treated with surgery and 3D conformal radiotherapy. Neurol India 52:248–250PubMed
13.
Zurück zum Zitat Sano H, Hayashi Y, Hasegawa M, Yamashita J (2004) Subfrontal schwannoma without hyposmia. Neurol Med Chir (Tokyo) 44:591–594CrossRef Sano H, Hayashi Y, Hasegawa M, Yamashita J (2004) Subfrontal schwannoma without hyposmia. Neurol Med Chir (Tokyo) 44:591–594CrossRef
14.
Zurück zum Zitat Sun W, Gao HB, Luo J, Yu CJ (2009) Subfrontal schwannoma—a case report. Chin Clin Med J 4:229–232 Sun W, Gao HB, Luo J, Yu CJ (2009) Subfrontal schwannoma—a case report. Chin Clin Med J 4:229–232
15.
Zurück zum Zitat Yako K, Morita A, Ueki K, Kirino T (2005) Subfrontal schwannoma. Acta Neurochir (Wien) 147:655–658CrossRef Yako K, Morita A, Ueki K, Kirino T (2005) Subfrontal schwannoma. Acta Neurochir (Wien) 147:655–658CrossRef
16.
17.
Zurück zum Zitat Sehrbundt V, Pau A, Turtas S (1973) Olfactory groove neurinomas. J Neurosurg Sci 17:193–196 Sehrbundt V, Pau A, Turtas S (1973) Olfactory groove neurinomas. J Neurosurg Sci 17:193–196
18.
Zurück zum Zitat Wewetzer K, Verdu E, Angelov DN, Navarro X (2002) Olfactory ensheathing glia and Schwann cells: two of a kind? Cell Tissue Res 309:337–345CrossRefPubMed Wewetzer K, Verdu E, Angelov DN, Navarro X (2002) Olfactory ensheathing glia and Schwann cells: two of a kind? Cell Tissue Res 309:337–345CrossRefPubMed
19.
Zurück zum Zitat Vincent AJ, Taylor JM, Choi-Lundberg DL, West AK, Chuah MI (2005) Genetic expression profile of olfactory ensheathing cells is distinct from that of Schwann cells and astrocytes. Glia 51:132–147CrossRefPubMed Vincent AJ, Taylor JM, Choi-Lundberg DL, West AK, Chuah MI (2005) Genetic expression profile of olfactory ensheathing cells is distinct from that of Schwann cells and astrocytes. Glia 51:132–147CrossRefPubMed
20.
Zurück zum Zitat Barnett SC, Alexander CL, Iwashita Y, Gilson JM, Crowther J, Clark L, Dunn LT, Papanastassiou V, Kennedy PG, Franklin RJ (2000) Identification of a human olfactory ensheathing cell that can affect transplant-mediated remyelination of demyelinated CNS axons. Brain 123:1581–1588CrossRefPubMed Barnett SC, Alexander CL, Iwashita Y, Gilson JM, Crowther J, Clark L, Dunn LT, Papanastassiou V, Kennedy PG, Franklin RJ (2000) Identification of a human olfactory ensheathing cell that can affect transplant-mediated remyelination of demyelinated CNS axons. Brain 123:1581–1588CrossRefPubMed
21.
Zurück zum Zitat Santosh K, Kesavadas C, Radhakrishnan VV, Thomas B, Kapilamoorthy TR, Gupta AK (2007) Usefulness of T2*-weighted MR sequence for the diagnosis of subfrontal schwannoma. J Neuroradiol 34:330–333 Santosh K, Kesavadas C, Radhakrishnan VV, Thomas B, Kapilamoorthy TR, Gupta AK (2007) Usefulness of T2*-weighted MR sequence for the diagnosis of subfrontal schwannoma. J Neuroradiol 34:330–333
Metadaten
Titel
Olfactory ensheathing cell tumour: case report and literature review
verfasst von
Ioana Darie
Laurent Riffaud
Stéphan Saïkali
Gilles Brassier
Abderrahmane Hamlat
Publikationsdatum
01.11.2010
Verlag
Springer US
Erschienen in
Journal of Neuro-Oncology / Ausgabe 2/2010
Print ISSN: 0167-594X
Elektronische ISSN: 1573-7373
DOI
https://doi.org/10.1007/s11060-010-0162-4

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