Skip to main content
Erschienen in: European Archives of Oto-Rhino-Laryngology 1/2019

22.11.2018 | Rhinology

Olfactory function and olfactory bulb volume in Wilson’s disease

verfasst von: Nazan Degirmenci, Bayram Veyseller, Hasmet Hanagasi, Basar Bilgic, Defne Gurbuz, Ali Toprak, Orhan Ozturan

Erschienen in: European Archives of Oto-Rhino-Laryngology | Ausgabe 1/2019

Einloggen, um Zugang zu erhalten

Abstract

Purpose

To evaluate the olfactory function and the olfactory bulb (OB) volume changes in Wilson’s Disease (WD) patients.

Methods

A prospective, controlled, single-blinded study was planned. 12 patients with WD (Group 1) and 12 healthy subjects (Group 2) were included in the study. Connecticut Chemosensory Clinical Research Center (CCCRC) test was applied to evaluate olfactory functions. OB volumes were measured with a 1.5 T General Electric Signa Excite MRI scanner.

Results

There was a significant difference between the CCCRC scores of the two groups (p < 0.05). The difference of the OB volumes of the two groups was insignificant (p > 0.05).

Conclusions

WD patients are likely to experience olfactory dysfunction, so its assessment may be a useful tool to the follow-up care of these patients, although further studies are needed to evaluate correlations in WD evolution.
Literatur
Metadaten
Titel
Olfactory function and olfactory bulb volume in Wilson’s disease
verfasst von
Nazan Degirmenci
Bayram Veyseller
Hasmet Hanagasi
Basar Bilgic
Defne Gurbuz
Ali Toprak
Orhan Ozturan
Publikationsdatum
22.11.2018
Verlag
Springer Berlin Heidelberg
Erschienen in
European Archives of Oto-Rhino-Laryngology / Ausgabe 1/2019
Print ISSN: 0937-4477
Elektronische ISSN: 1434-4726
DOI
https://doi.org/10.1007/s00405-018-5216-9

Weitere Artikel der Ausgabe 1/2019

European Archives of Oto-Rhino-Laryngology 1/2019 Zur Ausgabe

Update HNO

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert – ganz bequem per eMail.