Skip to main content
Erschienen in: Annals of Surgical Oncology 9/2019

29.05.2019 | Breast Oncology

Omitting Postoperative Wound Drainage After Mastectomy With Skin-Flap Quilting

verfasst von: B. ten Wolde, MD, F. F. R. Strobbe, BSc, M. Schlooz-de Vries, MD, F. J. H. van den Wildenberg, MD, PhD, M. Keemers-Gels, MD, PhD, J. H. W. de Wilt, MD, PhD, L. J. A. Strobbe, MD, PhD

Erschienen in: Annals of Surgical Oncology | Ausgabe 9/2019

Einloggen, um Zugang zu erhalten

Abstract

Background

Seroma is the most frequent complication after mastectomy (ME) and axillary lymph node dissection (ALND). The quilting suture technique, in which skin flaps are sutured to the underlying muscle, was previously investigated and found to reduce seroma incidence after ME and ALND. This study aimed to investigate whether postoperative wound drainage can safely be omitted when quilting sutures are applied.

Methods

Two groups with a total of 251 consecutive patients who underwent ME, ALND, or both were retrospectively compared. The first group underwent quilting sutures with wound vacuum drainage, and the second group underwent quilting sutures without wound drainage. The primary outcome was the incidence of postoperative clinically significant seroma (CSS). The secondary outcomes were the incidence of postoperative infection, bleeding complications, wound dehiscence, and flap necrosis.

Results

The group without a postoperative drain (n = 166) had a significantly lower CSS incidence (8.4%) than the group with a postoperative drain (n = 85, 21.2%) (p < 0.05). In the multivariate analysis, no significant predictors were found for seroma formation. Wound complications significantly decreased, from 31.8% in the group with a drain group to 17.5% in the group without a drain (p < 0.05).

Conclusion

This study showed that the postoperative drain can be omitted when quilting sutures are applied in ME, ALND, or both. This facilitates day care mastectomy, eliminating drain-related care, discomfort, and related expenses.
Literatur
1.
Zurück zum Zitat van der Waal D, Verbeek AL, den Heeten GJ, Ripping TM, Tjan-Heijnen VC, Broeders MJ. Breast cancer diagnosis and death in the Netherlands: a changing burden. Eur J Public Health. 2015;25:320–4.CrossRefPubMed van der Waal D, Verbeek AL, den Heeten GJ, Ripping TM, Tjan-Heijnen VC, Broeders MJ. Breast cancer diagnosis and death in the Netherlands: a changing burden. Eur J Public Health. 2015;25:320–4.CrossRefPubMed
5.
Zurück zum Zitat Bryant M, Baum M. Postoperative seroma following mastectomy and axillary dissection. Br J Surg. 1987;74:1187.CrossRefPubMed Bryant M, Baum M. Postoperative seroma following mastectomy and axillary dissection. Br J Surg. 1987;74:1187.CrossRefPubMed
6.
Zurück zum Zitat Woodworth PA, McBoyle MF, Helmer SD, Beamer RL. Seroma formation after breast cancer surgery: incidence and predicting factors. Am Surg. 2000;66:444–50; discussion 50–1. Woodworth PA, McBoyle MF, Helmer SD, Beamer RL. Seroma formation after breast cancer surgery: incidence and predicting factors. Am Surg. 2000;66:444–50; discussion 50–1.
7.
Zurück zum Zitat Jeffrey SS, Goodson WH III, Ikeda DM, Birdwell RL, Bogetz MS. Axillary lymphadenectomy for breast cancer without axillary drainage. Arch Surg. 1995;130:909–12; discussion 12–3. Jeffrey SS, Goodson WH III, Ikeda DM, Birdwell RL, Bogetz MS. Axillary lymphadenectomy for breast cancer without axillary drainage. Arch Surg. 1995;130:909–12; discussion 12–3.
8.
Zurück zum Zitat Ten Wolde B, Kuiper M, de Wilt JHW, Strobbe LJA. Postoperative complications after breast cancer surgery are not related to age. Ann Surg Oncol. 2017;24:1861–7.CrossRefPubMed Ten Wolde B, Kuiper M, de Wilt JHW, Strobbe LJA. Postoperative complications after breast cancer surgery are not related to age. Ann Surg Oncol. 2017;24:1861–7.CrossRefPubMed
9.
Zurück zum Zitat Boostrom SY, Throckmorton AD, Boughey JC, Holifield AC, Zakaria S, Hoskin TL, et al. Incidence of clinically significant seroma after breast and axillary surgery. J Am Coll Surg. 2009;208:148–50.CrossRefPubMed Boostrom SY, Throckmorton AD, Boughey JC, Holifield AC, Zakaria S, Hoskin TL, et al. Incidence of clinically significant seroma after breast and axillary surgery. J Am Coll Surg. 2009;208:148–50.CrossRefPubMed
10.
Zurück zum Zitat Aitken DR, Minton JP. Complications associated with mastectomy. Surg Clin North Am. 1983;63:1331–52.CrossRefPubMed Aitken DR, Minton JP. Complications associated with mastectomy. Surg Clin North Am. 1983;63:1331–52.CrossRefPubMed
11.
Zurück zum Zitat Chilson TR, Chan FD, Lonser RR, Wu TM, Aitken DR. Seroma prevention after modified radical mastectomy. Am Surg. 1992;58:750–4.PubMed Chilson TR, Chan FD, Lonser RR, Wu TM, Aitken DR. Seroma prevention after modified radical mastectomy. Am Surg. 1992;58:750–4.PubMed
12.
Zurück zum Zitat Almond LM, Khodaverdi L, Kumar B, Coveney EC. Flap anchoring following primary breast cancer surgery facilitates early hospital discharge and reduces costs. Breast Care Basel. 2010;5:97–101.CrossRefPubMedPubMedCentral Almond LM, Khodaverdi L, Kumar B, Coveney EC. Flap anchoring following primary breast cancer surgery facilitates early hospital discharge and reduces costs. Breast Care Basel. 2010;5:97–101.CrossRefPubMedPubMedCentral
13.
Zurück zum Zitat Tadych K, Donegan WL. Postmastectomy seromas and wound drainage. Surg Gynecol Obstet. 1987;165:483–7.PubMed Tadych K, Donegan WL. Postmastectomy seromas and wound drainage. Surg Gynecol Obstet. 1987;165:483–7.PubMed
14.
Zurück zum Zitat Sajid MS, Hutson KH, Rapisarda IF, Bonomi R. Fibrin glue instillation under skin flaps to prevent seroma-related morbidity following breast and axillary surgery. Cochrane Database Syst Rev. 2013(5):CD009557. Sajid MS, Hutson KH, Rapisarda IF, Bonomi R. Fibrin glue instillation under skin flaps to prevent seroma-related morbidity following breast and axillary surgery. Cochrane Database Syst Rev. 2013(5):CD009557.
15.
Zurück zum Zitat Burak WE Jr, Goodman PS, Young DC, Farrar WB. Seroma formation following axillary dissection for breast cancer: risk factors and lack of influence of bovine thrombin. J Surg Oncol. 1997;64:27–31.CrossRefPubMed Burak WE Jr, Goodman PS, Young DC, Farrar WB. Seroma formation following axillary dissection for breast cancer: risk factors and lack of influence of bovine thrombin. J Surg Oncol. 1997;64:27–31.CrossRefPubMed
16.
Zurück zum Zitat O’Hea BJ, Ho MN, Petrek JA. External compression dressing versus standard dressing after axillary lymphadenectomy. Am J Surg. 1999;177:450–3.CrossRefPubMed O’Hea BJ, Ho MN, Petrek JA. External compression dressing versus standard dressing after axillary lymphadenectomy. Am J Surg. 1999;177:450–3.CrossRefPubMed
17.
Zurück zum Zitat Srivastava V, Basu S, Shukla VK. Seroma formation after breast cancer surgery: what we have learned in the last two decades. J Breast Cancer. 2012;15:373–80.CrossRefPubMedPubMedCentral Srivastava V, Basu S, Shukla VK. Seroma formation after breast cancer surgery: what we have learned in the last two decades. J Breast Cancer. 2012;15:373–80.CrossRefPubMedPubMedCentral
18.
Zurück zum Zitat van Bemmel AJ, van de Velde CJ, Schmitz RF, Liefers GJ. Prevention of seroma formation after axillary dissection in breast cancer: a systematic review. Eur J Surg Oncol. 2011;37:829–35.CrossRefPubMed van Bemmel AJ, van de Velde CJ, Schmitz RF, Liefers GJ. Prevention of seroma formation after axillary dissection in breast cancer: a systematic review. Eur J Surg Oncol. 2011;37:829–35.CrossRefPubMed
19.
Zurück zum Zitat Kuroi K, Shimozuma K, Taguchi T, Imai H, Yamashiro H, Ohsumi S, et al. Effect of mechanical closure of dead space on seroma formation after breast surgery. Breast Cancer. 2006;13:260–5.CrossRefPubMed Kuroi K, Shimozuma K, Taguchi T, Imai H, Yamashiro H, Ohsumi S, et al. Effect of mechanical closure of dead space on seroma formation after breast surgery. Breast Cancer. 2006;13:260–5.CrossRefPubMed
20.
Zurück zum Zitat van Bastelaar J, van Roozendaal L, Granzier R, Beets G, Vissers Y. A systematic review of flap fixation techniques in reducing seroma formation and its sequelae after mastectomy. Breast Cancer Res Treat. 2018;167:409–16.CrossRefPubMed van Bastelaar J, van Roozendaal L, Granzier R, Beets G, Vissers Y. A systematic review of flap fixation techniques in reducing seroma formation and its sequelae after mastectomy. Breast Cancer Res Treat. 2018;167:409–16.CrossRefPubMed
21.
Zurück zum Zitat Sakkary MA. The value of mastectomy flap fixation in reducing fluid drainage and seroma formation in breast cancer patients. World J Surg Oncol. 2012;10:8.CrossRefPubMedPubMedCentral Sakkary MA. The value of mastectomy flap fixation in reducing fluid drainage and seroma formation in breast cancer patients. World J Surg Oncol. 2012;10:8.CrossRefPubMedPubMedCentral
22.
Zurück zum Zitat ten Wolde B, van den Wildenberg FJ, Keemers-Gels ME, Polat F, Strobbe LJ. Quilting prevents seroma formation following breast cancer surgery: closing the dead space by quilting prevents seroma following axillary lymph node dissection and mastectomy. Ann Surg Oncol. 2014;21:802–7.CrossRefPubMed ten Wolde B, van den Wildenberg FJ, Keemers-Gels ME, Polat F, Strobbe LJ. Quilting prevents seroma formation following breast cancer surgery: closing the dead space by quilting prevents seroma following axillary lymph node dissection and mastectomy. Ann Surg Oncol. 2014;21:802–7.CrossRefPubMed
23.
Zurück zum Zitat Taylor JC, Rai S, Hoar F, Brown H, Vishwanath L. Breast cancer surgery without suction drainage: the impact of adopting a “no drains” policy on symptomatic seroma formation rates. Eur J Surg Oncol. 2013;39:334–8.CrossRefPubMed Taylor JC, Rai S, Hoar F, Brown H, Vishwanath L. Breast cancer surgery without suction drainage: the impact of adopting a “no drains” policy on symptomatic seroma formation rates. Eur J Surg Oncol. 2013;39:334–8.CrossRefPubMed
24.
Zurück zum Zitat Purushotham AD, McLatchie E, Young D, George WD, Stallard S, Doughty J, et al. Randomized clinical trial of no wound drains and early discharge in the treatment of women with breast cancer. Br J Surg. 2002;89:286–92.CrossRefPubMed Purushotham AD, McLatchie E, Young D, George WD, Stallard S, Doughty J, et al. Randomized clinical trial of no wound drains and early discharge in the treatment of women with breast cancer. Br J Surg. 2002;89:286–92.CrossRefPubMed
25.
Zurück zum Zitat Gupta R, Pate K, Varshney S, Goddard J, Royle GT. A comparison of 5-day and 8-day drainage following mastectomy and axillary clearance. Eur J Surg Oncol. 2001;27:26–30.CrossRefPubMed Gupta R, Pate K, Varshney S, Goddard J, Royle GT. A comparison of 5-day and 8-day drainage following mastectomy and axillary clearance. Eur J Surg Oncol. 2001;27:26–30.CrossRefPubMed
26.
Zurück zum Zitat Bonnema J, van Geel AN, Ligtenstein DA, Schmitz PI, Wiggers T. A prospective randomized trial of high versus low vacuum drainage after axillary dissection for breast cancer. Am J Surg. 1997;173:76–9.CrossRefPubMed Bonnema J, van Geel AN, Ligtenstein DA, Schmitz PI, Wiggers T. A prospective randomized trial of high versus low vacuum drainage after axillary dissection for breast cancer. Am J Surg. 1997;173:76–9.CrossRefPubMed
27.
Zurück zum Zitat Zavotsky J, Jones RC, Brennan MB, Giuliano AE. Evaluation of axillary lymphadenectomy without axillary drainage for patients undergoing breast-conserving therapy. Ann Surg Oncol. 1998;5:227–31.CrossRefPubMed Zavotsky J, Jones RC, Brennan MB, Giuliano AE. Evaluation of axillary lymphadenectomy without axillary drainage for patients undergoing breast-conserving therapy. Ann Surg Oncol. 1998;5:227–31.CrossRefPubMed
28.
Zurück zum Zitat Baker E, Piper J. Drainless mastectomy: is it safe and effective? Surgeon. 2017;15:267–71.CrossRef Baker E, Piper J. Drainless mastectomy: is it safe and effective? Surgeon. 2017;15:267–71.CrossRef
29.
Zurück zum Zitat Mazouni C, Mesnard C, Cloutier AS, Amabile MI, Bentivegna E, Garbay JR, et al. Quilting sutures reduces seroma in mastectomy. Clin Breast Cancer. 2015;15:289–93.CrossRefPubMed Mazouni C, Mesnard C, Cloutier AS, Amabile MI, Bentivegna E, Garbay JR, et al. Quilting sutures reduces seroma in mastectomy. Clin Breast Cancer. 2015;15:289–93.CrossRefPubMed
30.
Zurück zum Zitat Mannu GS, Qurihi K, Carey F, Ahmad MA, Hussien M. Quilting after mastectomy significantly reduces seroma formation. South African J Surg. 2015;53:50–4.CrossRef Mannu GS, Qurihi K, Carey F, Ahmad MA, Hussien M. Quilting after mastectomy significantly reduces seroma formation. South African J Surg. 2015;53:50–4.CrossRef
31.
Zurück zum Zitat Ouldamer L, Caille A, Giraudeau B, Body G. Quilting suture of mastectomy dead space compared with conventional closure with drain. Ann Surg Oncol. 2015;22:4233–40.CrossRefPubMed Ouldamer L, Caille A, Giraudeau B, Body G. Quilting suture of mastectomy dead space compared with conventional closure with drain. Ann Surg Oncol. 2015;22:4233–40.CrossRefPubMed
32.
Zurück zum Zitat Dindo D, Demartines N, Clavien PA. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg. 2004;240:205–13.CrossRefPubMedPubMedCentral Dindo D, Demartines N, Clavien PA. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg. 2004;240:205–13.CrossRefPubMedPubMedCentral
33.
Zurück zum Zitat He XD, Guo ZH, Tian JH, Yang KH, Xie XD. Whether drainage should be used after surgery for breast cancer? A systematic review of randomized controlled trials. Med Oncol. 2011;28(Suppl 1):S22–30.CrossRefPubMed He XD, Guo ZH, Tian JH, Yang KH, Xie XD. Whether drainage should be used after surgery for breast cancer? A systematic review of randomized controlled trials. Med Oncol. 2011;28(Suppl 1):S22–30.CrossRefPubMed
34.
Zurück zum Zitat Troost MS, Kempees CJ, de Roos MA. Breast cancer surgery without drains: no influence on seroma formation. Int J Surg. 2015;13:170–4.CrossRefPubMed Troost MS, Kempees CJ, de Roos MA. Breast cancer surgery without drains: no influence on seroma formation. Int J Surg. 2015;13:170–4.CrossRefPubMed
35.
Zurück zum Zitat Talbot ML, Magarey CJ. Reduced use of drains following axillary lymphadenectomy for breast cancer. ANZ J Surg. 2002;72:488–90.CrossRefPubMed Talbot ML, Magarey CJ. Reduced use of drains following axillary lymphadenectomy for breast cancer. ANZ J Surg. 2002;72:488–90.CrossRefPubMed
36.
Zurück zum Zitat Agrawal A, Ayantunde AA, Cheung KL. Concepts of seroma formation and prevention in breast cancer surgery. ANZ J Surg. 2006;76:1088–95.CrossRefPubMed Agrawal A, Ayantunde AA, Cheung KL. Concepts of seroma formation and prevention in breast cancer surgery. ANZ J Surg. 2006;76:1088–95.CrossRefPubMed
37.
Zurück zum Zitat Felippe WA, Werneck GL, Santoro-Lopes G. Surgical-site infection among women discharged with a drain in situ after breast cancer surgery. World J Surg. 2007;31:2293–9; discussion 300–1. Felippe WA, Werneck GL, Santoro-Lopes G. Surgical-site infection among women discharged with a drain in situ after breast cancer surgery. World J Surg. 2007;31:2293–9; discussion 300–1.
Metadaten
Titel
Omitting Postoperative Wound Drainage After Mastectomy With Skin-Flap Quilting
verfasst von
B. ten Wolde, MD
F. F. R. Strobbe, BSc
M. Schlooz-de Vries, MD
F. J. H. van den Wildenberg, MD, PhD
M. Keemers-Gels, MD, PhD
J. H. W. de Wilt, MD, PhD
L. J. A. Strobbe, MD, PhD
Publikationsdatum
29.05.2019
Verlag
Springer International Publishing
Erschienen in
Annals of Surgical Oncology / Ausgabe 9/2019
Print ISSN: 1068-9265
Elektronische ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-019-07411-x

Weitere Artikel der Ausgabe 9/2019

Annals of Surgical Oncology 9/2019 Zur Ausgabe

Update Chirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

S3-Leitlinie „Diagnostik und Therapie des Karpaltunnelsyndroms“

Karpaltunnelsyndrom BDC Leitlinien Webinare
CME: 2 Punkte

Das Karpaltunnelsyndrom ist die häufigste Kompressionsneuropathie peripherer Nerven. Obwohl die Anamnese mit dem nächtlichen Einschlafen der Hand (Brachialgia parästhetica nocturna) sehr typisch ist, ist eine klinisch-neurologische Untersuchung und Elektroneurografie in manchen Fällen auch eine Neurosonografie erforderlich. Im Anfangsstadium sind konservative Maßnahmen (Handgelenksschiene, Ergotherapie) empfehlenswert. Bei nicht Ansprechen der konservativen Therapie oder Auftreten von neurologischen Ausfällen ist eine Dekompression des N. medianus am Karpaltunnel indiziert.

Prof. Dr. med. Gregor Antoniadis
Berufsverband der Deutschen Chirurgie e.V.

S2e-Leitlinie „Distale Radiusfraktur“

Radiusfraktur BDC Leitlinien Webinare
CME: 2 Punkte

Das Webinar beschäftigt sich mit Fragen und Antworten zu Diagnostik und Klassifikation sowie Möglichkeiten des Ausschlusses von Zusatzverletzungen. Die Referenten erläutern, welche Frakturen konservativ behandelt werden können und wie. Das Webinar beantwortet die Frage nach aktuellen operativen Therapiekonzepten: Welcher Zugang, welches Osteosynthesematerial? Auf was muss bei der Nachbehandlung der distalen Radiusfraktur geachtet werden?

PD Dr. med. Oliver Pieske
Dr. med. Benjamin Meyknecht
Berufsverband der Deutschen Chirurgie e.V.

S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“

Appendizitis BDC Leitlinien Webinare
CME: 2 Punkte

Inhalte des Webinars zur S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“ sind die Darstellung des Projektes und des Erstellungswegs zur S1-Leitlinie, die Erläuterung der klinischen Relevanz der Klassifikation EAES 2015, die wissenschaftliche Begründung der wichtigsten Empfehlungen und die Darstellung stadiengerechter Therapieoptionen.

Dr. med. Mihailo Andric
Berufsverband der Deutschen Chirurgie e.V.