Skip to main content
Erschienen in: Journal of General Internal Medicine 3/2020

16.11.2020 | Original Research

Opioid Prescribing and Opioid Risk Mitigation Strategies in the Veterans Health Administration

verfasst von: Friedhelm Sandbrink, MD, Elizabeth M. Oliva, PhD, Tara L. McMullen, PhD, Amy R. Aylor, PharmD, MS, Michael A. Harvey, PharmD, Melissa L. Christopher, PharmD, Francesca Cunningham, PharmD, Taeko Minegishi, MS, Thomas Emmendorfer, PharmD, Jenie M. Perry, BS

Erschienen in: Journal of General Internal Medicine | Sonderheft 3/2020

Einloggen, um Zugang zu erhalten

Abstract

Introduction

The Veterans Health Administration (VHA) has taken a multifaceted approach to addressing opioid safety and promoting system-wide opioid stewardship.

Aim

To provide a comprehensive evaluation of current opioid prescribing practices and implementation of risk mitigation strategies in VHA.

Setting

VHA is the largest integrated health care system in the United States.

Program Description

VHA prescribing data in conjunction with implementation of opioid risk mitigation strategies are routinely tracked and reviewed by VHA’s Pharmacy Benefits Management Services (including Academic Detailing Service) and the Pain Management Program Office. Additional data are derived from the Partnered Evidence-Based Policy Resource Center (PEPReC) and from a 2019 survey of interdisciplinary pain management teams at VHA facilities. Prescribing data are reported quarterly until first quarter fiscal year 2020 (Q1FY2020), ending December 31, 2019.

Program Evaluation

VHA opioid dispensing peaked in 2012 with 679,376 Veterans receiving an opioid prescription, and when including tramadol, in 2013 with 869,956 Veterans. Since 2012, the number of Veterans dispensed an opioid decreased 56% and co-prescribed opioid/benzodiazepine decreased 83%. Veterans with high-dose opioids (≥ 100 mg morphine equivalent daily dose) decreased 77%. In Q1FY2020, among Veterans on long-term opioid therapy (LTOT), 91.1% had written informed consent, 90.8% had a urine drug screen, and 89.0% had a prescription drug monitoring program query. Naloxone was issued to 217,469 Veterans and resulted in > 1,000 documented overdose reversals. In 2019, interdisciplinary pain management teams were fully designated at 68%, partially designated at 28%, and not available at 4% of 140 VA parent facilities. Fifty percent of Veterans on opioids at very high risk for overdose/suicide received interdisciplinary team reviews.

Implications

VHA clinicians have greatly reduced their volume of opioid prescribing for pain management and expanded implementation of opioid risk mitigation strategies.

Impacts

VHA’s integrated health care system provides a model for opioid stewardship and interdisciplinary pain care.
Anhänge
Nur mit Berechtigung zugänglich
Literatur
1.
Zurück zum Zitat Nahin RL. Severe pain in Veterans: the effect of age and sex, and comparisons with the general population. J Pain. 2017:18(3):247-254.CrossRef Nahin RL. Severe pain in Veterans: the effect of age and sex, and comparisons with the general population. J Pain. 2017:18(3):247-254.CrossRef
3.
Zurück zum Zitat Lew HL, Otis JD, Tun C, Kerns RD, Clark ME, Cifu DX. Prevalence of chronic pain, posttraumatic stress disorder, and persistent postconcussive symptoms in OIF/OEF veterans: Polytrauma clinical triad. J Rehabil Res Dev. 2009;46(6):697-702.CrossRef Lew HL, Otis JD, Tun C, Kerns RD, Clark ME, Cifu DX. Prevalence of chronic pain, posttraumatic stress disorder, and persistent postconcussive symptoms in OIF/OEF veterans: Polytrauma clinical triad. J Rehabil Res Dev. 2009;46(6):697-702.CrossRef
4.
Zurück zum Zitat Bohnert AS, Ilgen MA, Galea S, McCarthy JF, Blow FC. Accidental poisoning mortality among patients in the Department of Veterans Affairs Health System. Med Care. 2011;49(4):393-6.CrossRef Bohnert AS, Ilgen MA, Galea S, McCarthy JF, Blow FC. Accidental poisoning mortality among patients in the Department of Veterans Affairs Health System. Med Care. 2011;49(4):393-6.CrossRef
5.
Zurück zum Zitat Okie S. A flood of opioids, a rising tide of deaths. N Engl J Med. 2010;363(21):1981-5.CrossRef Okie S. A flood of opioids, a rising tide of deaths. N Engl J Med. 2010;363(21):1981-5.CrossRef
6.
Zurück zum Zitat Bohnert AS, Ilgen MA. Understanding links among opioid use, overdose, and suicide. N Engl J Med. 2019;380(1):71-9.CrossRef Bohnert AS, Ilgen MA. Understanding links among opioid use, overdose, and suicide. N Engl J Med. 2019;380(1):71-9.CrossRef
7.
Zurück zum Zitat Gellad WF, Good CB, Shulkin DJ. Addressing the opioid epidemic in the United States: lessons from the Department of Veterans Affairs. JAMA Intern Med. 2017;177(5):611-612.CrossRef Gellad WF, Good CB, Shulkin DJ. Addressing the opioid epidemic in the United States: lessons from the Department of Veterans Affairs. JAMA Intern Med. 2017;177(5):611-612.CrossRef
8.
Zurück zum Zitat Avorn J, Soumerai SB. Improving drug-therapy decisions through educational outreach. A randomized controlled trial of academically based “detailing.” N Engl J Med. 1983;308(24):1457-1463.CrossRef Avorn J, Soumerai SB. Improving drug-therapy decisions through educational outreach. A randomized controlled trial of academically based “detailing.” N Engl J Med. 1983;308(24):1457-1463.CrossRef
9.
Zurück zum Zitat Wells DL, Popish S, Kay C, Torrise V, Christopher ML. VA Academic Detailing Service: Implementation and Lessons Learned. Fed Pract. 2016;33(5):66-69. Wells DL, Popish S, Kay C, Torrise V, Christopher ML. VA Academic Detailing Service: Implementation and Lessons Learned. Fed Pract. 2016;33(5):66-69.
10.
Zurück zum Zitat Popish SJ. Academic detailing: Using clinical evidence to improve care. Ment Health Clin. 2013;2(12):392-394.CrossRef Popish SJ. Academic detailing: Using clinical evidence to improve care. Ment Health Clin. 2013;2(12):392-394.CrossRef
11.
Zurück zum Zitat Bounthavong M, Harvey MA, Wells DL, et al. Trends in naloxone prescriptions prescribed after implementation of a National Academic Detailing Service in the Veterans Health Administration: A preliminary analysis. J Am Pharm Assoc. 2017;57:S68-72.CrossRef Bounthavong M, Harvey MA, Wells DL, et al. Trends in naloxone prescriptions prescribed after implementation of a National Academic Detailing Service in the Veterans Health Administration: A preliminary analysis. J Am Pharm Assoc. 2017;57:S68-72.CrossRef
14.
Zurück zum Zitat Comprehensive Addiction and Recovery Act of 2016, Pub. L. No 114-198, Stat. 524 (2016). Comprehensive Addiction and Recovery Act of 2016, Pub. L. No 114-198, Stat. 524 (2016).
15.
Zurück zum Zitat The Centers for Disease Control and Prevention. CDC Guideline for Prescribing Opioids for Chronic Pain- United States, 2016. MMWR. 2016; 65(1): 1-49. The Centers for Disease Control and Prevention. CDC Guideline for Prescribing Opioids for Chronic Pain- United States, 2016. MMWR. 2016; 65(1): 1-49.
18.
Zurück zum Zitat U.S. Department of Veterans Affairs. Conduct of Data-Based Case Reviews of Opioid-Exposed Patients With Risk Factors. VA Notice 2019-15. 2019. U.S. Department of Veterans Affairs. Conduct of Data-Based Case Reviews of Opioid-Exposed Patients With Risk Factors. VA Notice 2019-15. 2019.
19.
Zurück zum Zitat Kligler B, Bair MJ, Banerjea R, DeBar L, Ezeji-Okoye, Lisi A, Murphy JL, Sandbrink F, Cherkin DC. Clinical Policy Recommendations From the VHA State-of-the-Art Conference on Non-Pharmacological Approaches to Chronic Musculoskeletal Pain. J Gen Intern Med 2018;33(Suppl 1):16-23.CrossRef Kligler B, Bair MJ, Banerjea R, DeBar L, Ezeji-Okoye, Lisi A, Murphy JL, Sandbrink F, Cherkin DC. Clinical Policy Recommendations From the VHA State-of-the-Art Conference on Non-Pharmacological Approaches to Chronic Musculoskeletal Pain. J Gen Intern Med 2018;33(Suppl 1):16-23.CrossRef
20.
Zurück zum Zitat John S. McCain III, Daniel K. Akaka, and Samuel R. Johnson VA Maintaining Internal Systems and Strengthening Integrated Outside Networks Act of 2018 (VA MISSION Act of 2018), Pub. L. No 115-182, Stat. 2372 (2018). John S. McCain III, Daniel K. Akaka, and Samuel R. Johnson VA Maintaining Internal Systems and Strengthening Integrated Outside Networks Act of 2018 (VA MISSION Act of 2018), Pub. L. No 115-182, Stat. 2372 (2018).
21.
Zurück zum Zitat Minegishi T, Frakt AB, Garrido MM, et al. Randomized program evaluation of the Veterans Health Administration Stratification Tool for Opioid Risk Mitigation (STORM): A research and clinical operations partnership to examine effectiveness. Subst Abus. 2019;40(1):14-19.CrossRef Minegishi T, Frakt AB, Garrido MM, et al. Randomized program evaluation of the Veterans Health Administration Stratification Tool for Opioid Risk Mitigation (STORM): A research and clinical operations partnership to examine effectiveness. Subst Abus. 2019;40(1):14-19.CrossRef
23.
Zurück zum Zitat Oliva EM, Bowe T, Tavakoli S, et al. Development and applications of the Veterans Health Administration’s Stratification Tool for Opioid Risk Mitigation (STORM) to improve opioid safety and prevent overdose and suicide. Psychol Serv . 2017;14(1):34-39.CrossRef Oliva EM, Bowe T, Tavakoli S, et al. Development and applications of the Veterans Health Administration’s Stratification Tool for Opioid Risk Mitigation (STORM) to improve opioid safety and prevent overdose and suicide. Psychol Serv . 2017;14(1):34-39.CrossRef
24.
Zurück zum Zitat Minegishi T, Garrido MM, Pizer SD, Frankt, AB. Effectiveness of policy and risk targeting for opioid-related risk mitigation: a randomized programme evaluation with stepped-wedge design. BMJ. 2018;8:e020097. Minegishi T, Garrido MM, Pizer SD, Frankt, AB. Effectiveness of policy and risk targeting for opioid-related risk mitigation: a randomized programme evaluation with stepped-wedge design. BMJ. 2018;8:e020097.
26.
Zurück zum Zitat Lin LA, Bohnert ASB, Kerns RD, Clay MA, Ganoczy D, Ilgen MA. Impact of the Opioid Safety Initiative on opioid-related prescribing in veterans. Pain. 2017;158(5):833-839.CrossRef Lin LA, Bohnert ASB, Kerns RD, Clay MA, Ganoczy D, Ilgen MA. Impact of the Opioid Safety Initiative on opioid-related prescribing in veterans. Pain. 2017;158(5):833-839.CrossRef
27.
Zurück zum Zitat Hadlandsmyth K, Mosher H, Vander Weg MW, Lund BC. Decline in prescription opioids attributable to decreases in long-term use: a retrospective study in the Veterans Health Administration 2010–2016. J Gen Intern Med. 2018;33:818-824.CrossRef Hadlandsmyth K, Mosher H, Vander Weg MW, Lund BC. Decline in prescription opioids attributable to decreases in long-term use: a retrospective study in the Veterans Health Administration 2010–2016. J Gen Intern Med. 2018;33:818-824.CrossRef
28.
Zurück zum Zitat Harris Ragan AP, Aikens GB, Bounthavong M, Brittain K, Mirk A. Academic Detailing to Reduce Sedative-Hypnotic Prescribing in Older Veterans. J Pharm Pract. 2019:897190019870949. Harris Ragan AP, Aikens GB, Bounthavong M, Brittain K, Mirk A. Academic Detailing to Reduce Sedative-Hypnotic Prescribing in Older Veterans. J Pharm Pract. 2019:897190019870949.
29.
Zurück zum Zitat Frank JW, Carey E, Nolan C, Kerns RD, Sandbrink F, Gallagher R, Ho PM. Increased Nonopioid Chronic Pain Treatment in the Veterans Health Administration, 2010-2016. Pain Med. 2019; 20(5):869-877.CrossRef Frank JW, Carey E, Nolan C, Kerns RD, Sandbrink F, Gallagher R, Ho PM. Increased Nonopioid Chronic Pain Treatment in the Veterans Health Administration, 2010-2016. Pain Med. 2019; 20(5):869-877.CrossRef
31.
Zurück zum Zitat Herman PM, Yuan AH, Cefalu MS et al. The use of complementary and integrative health approaches for chronic musculoskeletal pain in younger US Veterans: An economic evaluation. PLoS One. 2019;14(6):e0217831.CrossRef Herman PM, Yuan AH, Cefalu MS et al. The use of complementary and integrative health approaches for chronic musculoskeletal pain in younger US Veterans: An economic evaluation. PLoS One. 2019;14(6):e0217831.CrossRef
32.
Zurück zum Zitat U.S. Department of Veterans Affairs. Opioid Taper Decision Tool. Available at: https://www.pbm.va.gov/PBM/AcademicDetailingService/Documents/Academic_Detailing_Educational_Material_Catalog/52_Pain_Opioid_Taper_Tool_IB_10_939_P96820.pdf. Accessed June 25, 2020. U.S. Department of Veterans Affairs. Opioid Taper Decision Tool. Available at: https://​www.​pbm.​va.​gov/​PBM/​AcademicDetailin​gService/​Documents/​Academic_​Detailing_​Educational_​Material_​Catalog/​52_​Pain_​Opioid_​Taper_​Tool_​IB_​10_​939_​P96820.​pdf.​ Accessed June 25, 2020.
34.
Zurück zum Zitat Dowell D, Compton WM, Giroir BP. Patient-Centered Reduction or Discontinuation of Long-term Opioid Analgesics. The HHS Guide for Clinicians. JAMA. 2019;322(19):1855-1856.CrossRef Dowell D, Compton WM, Giroir BP. Patient-Centered Reduction or Discontinuation of Long-term Opioid Analgesics. The HHS Guide for Clinicians. JAMA. 2019;322(19):1855-1856.CrossRef
37.
Zurück zum Zitat Lin LA, Peltzman T, McCarthy JF, Oliva EM, Trafton JM, Bohnert A. Changing trends in opioid overdose deaths and prescription opioid receipt among Veterans. Am J Prev Med. 2019; 57(1):106-110.CrossRef Lin LA, Peltzman T, McCarthy JF, Oliva EM, Trafton JM, Bohnert A. Changing trends in opioid overdose deaths and prescription opioid receipt among Veterans. Am J Prev Med. 2019; 57(1):106-110.CrossRef
Metadaten
Titel
Opioid Prescribing and Opioid Risk Mitigation Strategies in the Veterans Health Administration
verfasst von
Friedhelm Sandbrink, MD
Elizabeth M. Oliva, PhD
Tara L. McMullen, PhD
Amy R. Aylor, PharmD, MS
Michael A. Harvey, PharmD
Melissa L. Christopher, PharmD
Francesca Cunningham, PharmD
Taeko Minegishi, MS
Thomas Emmendorfer, PharmD
Jenie M. Perry, BS
Publikationsdatum
16.11.2020
Verlag
Springer International Publishing
Erschienen in
Journal of General Internal Medicine / Ausgabe Sonderheft 3/2020
Print ISSN: 0884-8734
Elektronische ISSN: 1525-1497
DOI
https://doi.org/10.1007/s11606-020-06258-3

Weitere Artikel der Sonderheft 3/2020

Journal of General Internal Medicine 3/2020 Zur Ausgabe

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.