Skip to main content
Erschienen in: Neurosurgical Review 2/2018

28.07.2016 | Review

Optical coherence tomography impacts the evaluation of visual pathway tumors

verfasst von: Ana Banc, Cristina Stan, Ioan Stefan Florian

Erschienen in: Neurosurgical Review | Ausgabe 2/2018

Einloggen, um Zugang zu erhalten

Abstract

The objective of this systematic literature review is to assess the role of retinal optical coherence tomography (OCT) in the evaluation of patients with tumors of the visual pathway. We performed a PubMed database search according to the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses. The search was restricted to articles published in English between 2000 and 2016, with at least 10 human adult participants enrolled. Twenty-seven articles met the eligibility criteria. All studies investigated tumors of the anterior visual pathway. Both time-domain and spectral-domain OCT technologies were used and the role of OCT as diagnostic and/or prognostic tool was studied. Retinal OCT provides structural information about ganglion cell axon integrity and is complementary to visual function examination. OCT is a prognostic factor for post-operative visual outcome.
Literatur
1.
Zurück zum Zitat Akashi A, Kanamori A, Ueda K, Matsumoto Y, Yamada Y, Nakamura M (2014) The detection of macular analysis by SD-OCT for optic chiasmal compression neuropathy and nasotemporal overlap. Invest Ophthalmol Vis Sci 55:4667–4672CrossRefPubMed Akashi A, Kanamori A, Ueda K, Matsumoto Y, Yamada Y, Nakamura M (2014) The detection of macular analysis by SD-OCT for optic chiasmal compression neuropathy and nasotemporal overlap. Invest Ophthalmol Vis Sci 55:4667–4672CrossRefPubMed
2.
Zurück zum Zitat Budenz DL, Anderson DR, Varma R, Schuman J, Cantor L, Savell J, Greenfield DS, Patella VM, Quigley HA, Tielsch J (2007) Determinants of normal retinal nerve fiber layer thickness measured by stratus OCT. Ophthalmology 114:1046–1052CrossRefPubMedPubMedCentral Budenz DL, Anderson DR, Varma R, Schuman J, Cantor L, Savell J, Greenfield DS, Patella VM, Quigley HA, Tielsch J (2007) Determinants of normal retinal nerve fiber layer thickness measured by stratus OCT. Ophthalmology 114:1046–1052CrossRefPubMedPubMedCentral
3.
Zurück zum Zitat Cennamo G, Auriemma RS, Cardone D, Grasso LFS, Velotti N, Simeoli C, Di Somma C, Pivonello R, Colao A, Crecchio G (2015) Evaluation of the retinal nerve fiber layer and ganglion cell complex thickness in pituitary macroadenomas without optic chiasmal compression. Eye 29:797–802CrossRefPubMedPubMedCentral Cennamo G, Auriemma RS, Cardone D, Grasso LFS, Velotti N, Simeoli C, Di Somma C, Pivonello R, Colao A, Crecchio G (2015) Evaluation of the retinal nerve fiber layer and ganglion cell complex thickness in pituitary macroadenomas without optic chiasmal compression. Eye 29:797–802CrossRefPubMedPubMedCentral
4.
Zurück zum Zitat Costa-Cunha LVF, Cunha LP, Malta RFS, Monteiro MLR (2009) Comparison of Fourier-domain and time-domain optical coherence tomography in the detection of band atrophy of the optic nerve. Am J Ophthalmol 147:56–63CrossRefPubMed Costa-Cunha LVF, Cunha LP, Malta RFS, Monteiro MLR (2009) Comparison of Fourier-domain and time-domain optical coherence tomography in the detection of band atrophy of the optic nerve. Am J Ophthalmol 147:56–63CrossRefPubMed
5.
Zurück zum Zitat Danesh-Meyer HV, Carroll SC, Foroozan R, Savino PJ, Fan J, Jiang Y, Vander Hoorn S (2006) Relationship between retinal nerve fiber layer and visual field sensitivity as measured by optical coherence tomography in chiasmal compression. Invest Ophthalmol Vis Sci 47:4827–4835CrossRefPubMed Danesh-Meyer HV, Carroll SC, Foroozan R, Savino PJ, Fan J, Jiang Y, Vander Hoorn S (2006) Relationship between retinal nerve fiber layer and visual field sensitivity as measured by optical coherence tomography in chiasmal compression. Invest Ophthalmol Vis Sci 47:4827–4835CrossRefPubMed
6.
Zurück zum Zitat Danesh-Meyer HV, Papchenko T, Savino PJ, Law A, Evans J, Gamble GD (2008) In vivo retinal nerve fiber layer thickness measured by optical coherence tomography predicts visual recovery after surgery for parachiasmal tumors. Invest Ophthalmol Vis Sci 49:1879–1885CrossRefPubMed Danesh-Meyer HV, Papchenko T, Savino PJ, Law A, Evans J, Gamble GD (2008) In vivo retinal nerve fiber layer thickness measured by optical coherence tomography predicts visual recovery after surgery for parachiasmal tumors. Invest Ophthalmol Vis Sci 49:1879–1885CrossRefPubMed
7.
Zurück zum Zitat Danesh-Meyer HV, Wong A, Papchenko T, Matheos K, Stylli S, Nichols A, Frampton C, Daniell M, Savino PJ, Kaye AH (2015) Optical coherence tomography predicts visual outcome for pituitary tumors. J Clin Neurosci 22:1098–1104CrossRefPubMed Danesh-Meyer HV, Wong A, Papchenko T, Matheos K, Stylli S, Nichols A, Frampton C, Daniell M, Savino PJ, Kaye AH (2015) Optical coherence tomography predicts visual outcome for pituitary tumors. J Clin Neurosci 22:1098–1104CrossRefPubMed
8.
Zurück zum Zitat Drexler W, Fujimoto JG (2008) State-of-the-art retinal optical coherence tomography. Prog Retin Eye Res 27(1):45–88CrossRefPubMed Drexler W, Fujimoto JG (2008) State-of-the-art retinal optical coherence tomography. Prog Retin Eye Res 27(1):45–88CrossRefPubMed
9.
Zurück zum Zitat Fujimoto JG, Pitris C, Boppart SA, Brezinski ME (2000) Optical coherence tomography: an emerging technology for biomedical imaging and optical biopsy. Neoplasia 2(1–2):9–25CrossRefPubMedPubMedCentral Fujimoto JG, Pitris C, Boppart SA, Brezinski ME (2000) Optical coherence tomography: an emerging technology for biomedical imaging and optical biopsy. Neoplasia 2(1–2):9–25CrossRefPubMedPubMedCentral
10.
Zurück zum Zitat Galetta KM, Calabresi PA, Frohman EM, Balcer LJ (2011) Optical coherence tomography (OCT): imaging the visual pathway as a model for neurodegeneration. Neurotherapeutics 8:117–132CrossRefPubMedPubMedCentral Galetta KM, Calabresi PA, Frohman EM, Balcer LJ (2011) Optical coherence tomography (OCT): imaging the visual pathway as a model for neurodegeneration. Neurotherapeutics 8:117–132CrossRefPubMedPubMedCentral
11.
Zurück zum Zitat Garcia T, Sanchez S, Litre CF, Radoi C, Delemer B, Rousseaux P, Ducasse A, Arndt C (2014) Prognostic value of retinal nerve fiber layer thickness for postoperative peripheral visual field recovery in optic chiasm compression. J Neurosurg 121:165–169CrossRefPubMed Garcia T, Sanchez S, Litre CF, Radoi C, Delemer B, Rousseaux P, Ducasse A, Arndt C (2014) Prognostic value of retinal nerve fiber layer thickness for postoperative peripheral visual field recovery in optic chiasm compression. J Neurosurg 121:165–169CrossRefPubMed
12.
Zurück zum Zitat Harwerth RS, Wheat JL (2008) Modeling the effects of aging on retinal ganglion cell density and nerve fiber layer thickness. Graefes Arch Clin Exp Ophthalmol 246:305–314CrossRefPubMed Harwerth RS, Wheat JL (2008) Modeling the effects of aging on retinal ganglion cell density and nerve fiber layer thickness. Graefes Arch Clin Exp Ophthalmol 246:305–314CrossRefPubMed
14.
Zurück zum Zitat Jacob M, Raverot G, Jouanneau E, Borson-Chazot F, Perrin G, Rabilloud M, Tilikete C, Bernard M, Vighetto A (2009) Predicting visual outcome after treatment of pituitary adenomas with optical coherence tomography. Am J Ophthalmol 147:64–70CrossRefPubMed Jacob M, Raverot G, Jouanneau E, Borson-Chazot F, Perrin G, Rabilloud M, Tilikete C, Bernard M, Vighetto A (2009) Predicting visual outcome after treatment of pituitary adenomas with optical coherence tomography. Am J Ophthalmol 147:64–70CrossRefPubMed
15.
Zurück zum Zitat Jindahra P, Petrie A, Plant GT (2009) Retrograde trans-synaptic retinal ganglion cell loss identified by optical coherence tomography. Brain 132:628–634CrossRefPubMed Jindahra P, Petrie A, Plant GT (2009) Retrograde trans-synaptic retinal ganglion cell loss identified by optical coherence tomography. Brain 132:628–634CrossRefPubMed
16.
Zurück zum Zitat Kanamori A, Nakamura M, Matsui N, Nagai A, Nakanishi Y, Kusuhara S, Yamada Y, Negi A (2004) Optical coherence tomography detects characteristic retinal nerve fiber layer thickness corresponding to band atrophy of the optic disc. Ophthalmology 111:2278–2283CrossRefPubMed Kanamori A, Nakamura M, Matsui N, Nagai A, Nakanishi Y, Kusuhara S, Yamada Y, Negi A (2004) Optical coherence tomography detects characteristic retinal nerve fiber layer thickness corresponding to band atrophy of the optic disc. Ophthalmology 111:2278–2283CrossRefPubMed
17.
Zurück zum Zitat Kanamori A, Nakamura M, Yamada Y, Negi A (2013) Spectral-domain optical coherence tomography detects optic atrophy due to optic tract syndrome. Graefes Arch Clin Exp Ophthalmol 251:591–595CrossRefPubMed Kanamori A, Nakamura M, Yamada Y, Negi A (2013) Spectral-domain optical coherence tomography detects optic atrophy due to optic tract syndrome. Graefes Arch Clin Exp Ophthalmol 251:591–595CrossRefPubMed
18.
Zurück zum Zitat Keller J, Sanchez-Dalmau BF, Villoslada P (2014) Lesions in the posterior visual pathway promote trans-synaptic degeneration of retinal ganglion cells. PLoS One 9(5):e97444CrossRefPubMedPubMedCentral Keller J, Sanchez-Dalmau BF, Villoslada P (2014) Lesions in the posterior visual pathway promote trans-synaptic degeneration of retinal ganglion cells. PLoS One 9(5):e97444CrossRefPubMedPubMedCentral
19.
Zurück zum Zitat Leung CKS, Yu M, Weinreb RN, Ye C, Liu S, Lai G, Lam DSC (2012) Retinal nerve fiber layer imaging with spectral-domain optical coherence tomography. Ophthalmology 119:731–737CrossRefPubMed Leung CKS, Yu M, Weinreb RN, Ye C, Liu S, Lai G, Lam DSC (2012) Retinal nerve fiber layer imaging with spectral-domain optical coherence tomography. Ophthalmology 119:731–737CrossRefPubMed
20.
Zurück zum Zitat Loo JL, Tian J, Miller NR, Subramanian PS (2013) Use of optical coherence tomography in predicting post-treatment visual outcome in anterior visual pathway meningiomas. Br J Ophthalmol 97:1455–1458CrossRefPubMed Loo JL, Tian J, Miller NR, Subramanian PS (2013) Use of optical coherence tomography in predicting post-treatment visual outcome in anterior visual pathway meningiomas. Br J Ophthalmol 97:1455–1458CrossRefPubMed
22.
Zurück zum Zitat Monteiro MLR, Costa-Cunha LVF, Cunha LP, Malta RFS (2010) Correlation between macular and retinal nerve fiber layer Fourier-domain OCT measurements and visual loss in chiasmal compression. Eye 24:1382–1390CrossRefPubMed Monteiro MLR, Costa-Cunha LVF, Cunha LP, Malta RFS (2010) Correlation between macular and retinal nerve fiber layer Fourier-domain OCT measurements and visual loss in chiasmal compression. Eye 24:1382–1390CrossRefPubMed
23.
Zurück zum Zitat Monteiro MLR, Cunha LP, Costa-Cunha LVF, Maia OO Jr, Oyamada MK (2009) Relationship between optical coherence tomography, pattern electroretinogram and automated perimetry in eyes with temporal hemianopia from chiasmal compression. Invest Ophthalmol Vis Sci 50:3535–3541CrossRefPubMed Monteiro MLR, Cunha LP, Costa-Cunha LVF, Maia OO Jr, Oyamada MK (2009) Relationship between optical coherence tomography, pattern electroretinogram and automated perimetry in eyes with temporal hemianopia from chiasmal compression. Invest Ophthalmol Vis Sci 50:3535–3541CrossRefPubMed
24.
Zurück zum Zitat Monteiro MLR, Cunha LP, Vessani RM (2008) Comparison of retinal nerve fiber layer measurements using stratus OCT fast and regular scan protocols in eyes with band atrophy of the optic nerve and normal controls. Arq Bras Oftalmol 71(4):534–539CrossRefPubMed Monteiro MLR, Cunha LP, Vessani RM (2008) Comparison of retinal nerve fiber layer measurements using stratus OCT fast and regular scan protocols in eyes with band atrophy of the optic nerve and normal controls. Arq Bras Oftalmol 71(4):534–539CrossRefPubMed
25.
Zurück zum Zitat Monteiro MLR, Hokazono K, Cunha LP, Oyamada MK (2013) Correlation between multifocal pattern electroretinography and Fourier-domain OCT in eyes with temporal hemianopia from chiasmal compression. Graefes Arch Clin Exp Ophthalmol 251:903–915CrossRefPubMed Monteiro MLR, Hokazono K, Cunha LP, Oyamada MK (2013) Correlation between multifocal pattern electroretinography and Fourier-domain OCT in eyes with temporal hemianopia from chiasmal compression. Graefes Arch Clin Exp Ophthalmol 251:903–915CrossRefPubMed
26.
Zurück zum Zitat Monteiro MLR, Hokazono K, Fernandes DB, Costa-Cunha LVF, Sousa RM, Raza AS, Wang DL, Hood DC (2014) Evaluation of inner retinal layers in eyes with temporal hemianoptic visual loss from chiasmal compression using optical coherence tomography. Invest Ophthalmol Vis Sci 55:3328–3336CrossRefPubMedPubMedCentral Monteiro MLR, Hokazono K, Fernandes DB, Costa-Cunha LVF, Sousa RM, Raza AS, Wang DL, Hood DC (2014) Evaluation of inner retinal layers in eyes with temporal hemianoptic visual loss from chiasmal compression using optical coherence tomography. Invest Ophthalmol Vis Sci 55:3328–3336CrossRefPubMedPubMedCentral
27.
Zurück zum Zitat Monteiro MLR, Leal BC, Rosa AAM, Bronstein MD (2004) Optical coherence tomography analysis of axonal loss in band atrophy of the optic nerve. Br J Ophthalmol 88:896–899CrossRefPubMedPubMedCentral Monteiro MLR, Leal BC, Rosa AAM, Bronstein MD (2004) Optical coherence tomography analysis of axonal loss in band atrophy of the optic nerve. Br J Ophthalmol 88:896–899CrossRefPubMedPubMedCentral
28.
Zurück zum Zitat Monteiro MLR, Moura FC (2008) Comparison of the GDx VCC scanning laser polarimeter and the stratus optical coherence tomograph in the detection of band atrophy of the optic nerve. Eye 22:641–648CrossRefPubMed Monteiro MLR, Moura FC (2008) Comparison of the GDx VCC scanning laser polarimeter and the stratus optical coherence tomograph in the detection of band atrophy of the optic nerve. Eye 22:641–648CrossRefPubMed
29.
Zurück zum Zitat Moon CH, Hwang SC, Ohn YH, Park TK (2011) The time course of visual field recovery and changes of retinal ganglion cells after optic chiasmal compression. Invest Ophthalmol Vis Sci 52:7966–7973CrossRefPubMed Moon CH, Hwang SC, Ohn YH, Park TK (2011) The time course of visual field recovery and changes of retinal ganglion cells after optic chiasmal compression. Invest Ophthalmol Vis Sci 52:7966–7973CrossRefPubMed
30.
Zurück zum Zitat Moon CH, Lee SH, Kim BT, Hwang SC, Ohn YH, Park TK (2012) Diagnostic ability of retinal nerve fiber layer thickness measurements and neurologic Hemifield test to detect chiasmal compression. Invest Ophthalmol Vis Sci 53:5410–5415CrossRefPubMed Moon CH, Lee SH, Kim BT, Hwang SC, Ohn YH, Park TK (2012) Diagnostic ability of retinal nerve fiber layer thickness measurements and neurologic Hemifield test to detect chiasmal compression. Invest Ophthalmol Vis Sci 53:5410–5415CrossRefPubMed
31.
Zurück zum Zitat Moura FC, Costa-Cunha LVF, Malta RFS, Monteiro MLR (2010) Relationship between visual field sensitivity loss and quadrantic macular thickness measured with stratus-optical coherence tomography in patients with chiasmal syndrome. Arq Bras Oftalmol 73(5):409–413CrossRefPubMed Moura FC, Costa-Cunha LVF, Malta RFS, Monteiro MLR (2010) Relationship between visual field sensitivity loss and quadrantic macular thickness measured with stratus-optical coherence tomography in patients with chiasmal syndrome. Arq Bras Oftalmol 73(5):409–413CrossRefPubMed
32.
Zurück zum Zitat Moura FC, Medeiros FA, Monteiro MLR (2007) Evaluation of macular thickness measurements for detection of band atrophy of the optic nerve using optical coherence tomography. Ophthalmology 114:175–181CrossRefPubMed Moura FC, Medeiros FA, Monteiro MLR (2007) Evaluation of macular thickness measurements for detection of band atrophy of the optic nerve using optical coherence tomography. Ophthalmology 114:175–181CrossRefPubMed
33.
Zurück zum Zitat Nakamura M, Ishikawa-Tabuchi K, Kanamori A, Yamada Y, Negi A (2012) Better performance of RTVue than cirrus spectral-domain optical coherence tomography in detecting band atrophy of the optic nerve. Graefes Arch Clin Exp Ophthalmol 250:1499–1507CrossRefPubMed Nakamura M, Ishikawa-Tabuchi K, Kanamori A, Yamada Y, Negi A (2012) Better performance of RTVue than cirrus spectral-domain optical coherence tomography in detecting band atrophy of the optic nerve. Graefes Arch Clin Exp Ophthalmol 250:1499–1507CrossRefPubMed
34.
Zurück zum Zitat Ohkubo S, Higashide T, Takeda H, Murotani E, Hayashi Y, Sugiyama K (2012) Relationship between macular ganglion cell complex parameters and visual field parameters after tumor resection in chiasmal compression. Jpn J Ophthalmol 56:68–75CrossRefPubMed Ohkubo S, Higashide T, Takeda H, Murotani E, Hayashi Y, Sugiyama K (2012) Relationship between macular ganglion cell complex parameters and visual field parameters after tumor resection in chiasmal compression. Jpn J Ophthalmol 56:68–75CrossRefPubMed
35.
Zurück zum Zitat Parikh RS, Parikh SR, Sekhar GC, Prabakaran S, Babu JG, Thomas R (2007) Normal age-related decay of retinal nerve fiber layer thickness. Ophthalmology 114:921–926CrossRefPubMed Parikh RS, Parikh SR, Sekhar GC, Prabakaran S, Babu JG, Thomas R (2007) Normal age-related decay of retinal nerve fiber layer thickness. Ophthalmology 114:921–926CrossRefPubMed
36.
Zurück zum Zitat Park HH, Oh MC, Kim EH, Kim CY, Kim SH, Lee KS, Chang JH (2015) Use of optical coherence tomography to predict visual outcome in parachiasmal meningioma. J Neurosurg 123:1489–1499CrossRefPubMed Park HH, Oh MC, Kim EH, Kim CY, Kim SH, Lee KS, Chang JH (2015) Use of optical coherence tomography to predict visual outcome in parachiasmal meningioma. J Neurosurg 123:1489–1499CrossRefPubMed
37.
Zurück zum Zitat Sibony P, Strachovsky M, Honkanen R, Kupersmith MJ (2014) Optical coherence tomography shape analysis of the peripapillary retinal pigment epithelium layer in presumed optic nerve sheath meningiomas. J Neuroophthalmol 34:130–136CrossRefPubMed Sibony P, Strachovsky M, Honkanen R, Kupersmith MJ (2014) Optical coherence tomography shape analysis of the peripapillary retinal pigment epithelium layer in presumed optic nerve sheath meningiomas. J Neuroophthalmol 34:130–136CrossRefPubMed
38.
Zurück zum Zitat Ueda K, Kanamori A, Akashi A, Matsumoto Y, Yamada Y, Nakamura M (2015) Evaluation of the distribution pattern of the circumpapillary retinal nerve fiber layer from the nasal hemiretina. Br J Ophthalmol 99:1419–1423CrossRefPubMed Ueda K, Kanamori A, Akashi A, Matsumoto Y, Yamada Y, Nakamura M (2015) Evaluation of the distribution pattern of the circumpapillary retinal nerve fiber layer from the nasal hemiretina. Br J Ophthalmol 99:1419–1423CrossRefPubMed
40.
Zurück zum Zitat Yoneoka Y, Hatase T, Watanabe N, Jinguji S, Okada M, Takagi M, Fujii Y (2015) Early morphological recovery of the optic chiasm is associated with excellent visual outcome in patients with compressive chiasmal syndrome caused by pituitary tumors. Neurol Res 37(1):1–8CrossRefPubMed Yoneoka Y, Hatase T, Watanabe N, Jinguji S, Okada M, Takagi M, Fujii Y (2015) Early morphological recovery of the optic chiasm is associated with excellent visual outcome in patients with compressive chiasmal syndrome caused by pituitary tumors. Neurol Res 37(1):1–8CrossRefPubMed
41.
Zurück zum Zitat Ziemssen T, Ziemssen F (2013) Perspectives of an innovative ophthalmological technology: optical coherence tomography (OCT)—what should be of interest to the neurologist? Clin Neurol Neurosurg 115(Suppl 1):S55–S59CrossRefPubMed Ziemssen T, Ziemssen F (2013) Perspectives of an innovative ophthalmological technology: optical coherence tomography (OCT)—what should be of interest to the neurologist? Clin Neurol Neurosurg 115(Suppl 1):S55–S59CrossRefPubMed
Metadaten
Titel
Optical coherence tomography impacts the evaluation of visual pathway tumors
verfasst von
Ana Banc
Cristina Stan
Ioan Stefan Florian
Publikationsdatum
28.07.2016
Verlag
Springer Berlin Heidelberg
Erschienen in
Neurosurgical Review / Ausgabe 2/2018
Print ISSN: 0344-5607
Elektronische ISSN: 1437-2320
DOI
https://doi.org/10.1007/s10143-016-0772-1

Weitere Artikel der Ausgabe 2/2018

Neurosurgical Review 2/2018 Zur Ausgabe

Update Chirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

S3-Leitlinie „Diagnostik und Therapie des Karpaltunnelsyndroms“

Karpaltunnelsyndrom BDC Leitlinien Webinare
CME: 2 Punkte

Das Karpaltunnelsyndrom ist die häufigste Kompressionsneuropathie peripherer Nerven. Obwohl die Anamnese mit dem nächtlichen Einschlafen der Hand (Brachialgia parästhetica nocturna) sehr typisch ist, ist eine klinisch-neurologische Untersuchung und Elektroneurografie in manchen Fällen auch eine Neurosonografie erforderlich. Im Anfangsstadium sind konservative Maßnahmen (Handgelenksschiene, Ergotherapie) empfehlenswert. Bei nicht Ansprechen der konservativen Therapie oder Auftreten von neurologischen Ausfällen ist eine Dekompression des N. medianus am Karpaltunnel indiziert.

Prof. Dr. med. Gregor Antoniadis
Berufsverband der Deutschen Chirurgie e.V.

S2e-Leitlinie „Distale Radiusfraktur“

Radiusfraktur BDC Leitlinien Webinare
CME: 2 Punkte

Das Webinar beschäftigt sich mit Fragen und Antworten zu Diagnostik und Klassifikation sowie Möglichkeiten des Ausschlusses von Zusatzverletzungen. Die Referenten erläutern, welche Frakturen konservativ behandelt werden können und wie. Das Webinar beantwortet die Frage nach aktuellen operativen Therapiekonzepten: Welcher Zugang, welches Osteosynthesematerial? Auf was muss bei der Nachbehandlung der distalen Radiusfraktur geachtet werden?

PD Dr. med. Oliver Pieske
Dr. med. Benjamin Meyknecht
Berufsverband der Deutschen Chirurgie e.V.

S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“

Appendizitis BDC Leitlinien Webinare
CME: 2 Punkte

Inhalte des Webinars zur S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“ sind die Darstellung des Projektes und des Erstellungswegs zur S1-Leitlinie, die Erläuterung der klinischen Relevanz der Klassifikation EAES 2015, die wissenschaftliche Begründung der wichtigsten Empfehlungen und die Darstellung stadiengerechter Therapieoptionen.

Dr. med. Mihailo Andric
Berufsverband der Deutschen Chirurgie e.V.