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Erschienen in: Journal of Anesthesia 2/2017

20.12.2016 | Original Article

Oral 30% glucose provides sufficient sedation in newborns during MRI

verfasst von: H. Evren Eker, Oya Yalcin Cok, Bilin Çetinkaya, Anis Aribogan

Erschienen in: Journal of Anesthesia | Ausgabe 2/2017

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Abstract

Purpose

Newborns are often sedated during MRI but sedation itself creates adverse events and management is more challenging in this environment. Oral glucose/sucrose administration has been studied in newborns during painful procedures; however, its effectiveness in keeping newborns sleepy and motionlessness during painless procedures has not been demonstrated. The objective of this study was to describe effectiveness of oral 30% glucose administration by comparing with intravenous midazolam sedation for newborns during MRI.

Methods

One hundred twelve ASA II-III newborns who required care in the ICU and were scheduled for MRI with sedation were included. Group I received 30% glucose solution orally with 0.5–1 ml increments up to 2 ml/3 kg doses and group II received intravenous 0.1 mg/kg midazolam with 0.05 mg/kg repetition. The procedure was considered satisfactory when MRI images were not disturbed by patient movement after oral glucose or intravenous midazolam administration. The efficiency of the techniques, additional dose and rescue sedation requirements, blood glucose levels following oral 30% glucose suckling and presence of adverse events were recorded.

Results

Demographic data was similar between groups. The efficiency of the procedures were similar between groups (78.9%, in group I and 66.1%, in group II). The blood glucose levels were within normal range in group I whereas transient desaturation and apnea occurred in 8 neonates in group II (p = 0.006).

Conclusion

Oral 30% glucose administration for newborns during MRI is as effective as standard sedation protocol with midazolam. Thereby, we recommend and support the integration of this safe and reliable technique into routine practice for newborns during MRI.
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Metadaten
Titel
Oral 30% glucose provides sufficient sedation in newborns during MRI
verfasst von
H. Evren Eker
Oya Yalcin Cok
Bilin Çetinkaya
Anis Aribogan
Publikationsdatum
20.12.2016
Verlag
Springer Japan
Erschienen in
Journal of Anesthesia / Ausgabe 2/2017
Print ISSN: 0913-8668
Elektronische ISSN: 1438-8359
DOI
https://doi.org/10.1007/s00540-016-2296-9

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