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Erschienen in: Indian Journal of Gastroenterology 3/2016

23.05.2016 | Original Article

Oral pH in gastroesophageal reflux disease

verfasst von: S. Sujatha, Umesh Jalihal, Yashoda Devi, N. Rakesh, Pallavi Chauhan, Shivani Sharma

Erschienen in: Indian Journal of Gastroenterology | Ausgabe 3/2016

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Abstract

Aims and Objectives

The aim of this study is to compare surface pH in various parts of the oral cavity between patients with gastroesophageal reflux disease (GERD) and healthy controls.

Methods

Using a flat pH meter sensor, fixed electrode pen type digital pH meter, oral pH levels were assessed at different mucosal sites among 34 GERD patients and 32 healthy controls. Salivary flow rates and buffering capacity were also assessed in them. A thorough oral examination was performed to screen for any oral and dental changes.

Result

A significantly lower pH of 6.65 ± 0.13 (mean ± SD) was found in the GERD group compared to control group 7.23 ± 0.12 (p < 0.05). Least pH was found in the floor of the mouth 6.594 ± 0.17 and highest in the lower labial mucosa among the GERD patients. Salivary flow rate and buffering capacity were low in these patients. Significant changes were noticed in the hard and soft tissues of the oral cavity among the GERD group.

Conclusion

Oral mucosal pH is altered in GERD patients and may contribute to effects on the oral cavity.
Literatur
1.
Zurück zum Zitat Deschner WK, Benjamin SB. Extraesophageal manifestations of gastroesophageal reflux disease. Am J Gastroenterol. 1989;84:1–5.PubMed Deschner WK, Benjamin SB. Extraesophageal manifestations of gastroesophageal reflux disease. Am J Gastroenterol. 1989;84:1–5.PubMed
2.
Zurück zum Zitat Cazzonatto H Jr, Bernasconi GCR, Pedrazzolli JR. Gastroesophageal reflux and oral lesions: is the acid that bad? Gastroenterol Endosc Dig. 2003;22:42–6. Cazzonatto H Jr, Bernasconi GCR, Pedrazzolli JR. Gastroesophageal reflux and oral lesions: is the acid that bad? Gastroenterol Endosc Dig. 2003;22:42–6.
3.
Zurück zum Zitat Myklebust S, Espelid I, Svalestad S, Tveit AB. Dental health behavior, gastroesophageal disorders and dietary habits among Norwegian recruits in 1990 and 1999. Acta Odontol Scand. 2003;61:100–4.CrossRefPubMed Myklebust S, Espelid I, Svalestad S, Tveit AB. Dental health behavior, gastroesophageal disorders and dietary habits among Norwegian recruits in 1990 and 1999. Acta Odontol Scand. 2003;61:100–4.CrossRefPubMed
4.
Zurück zum Zitat Barron RP, Carmichael RP, Marcon MA, Sàndor GK. Dental erosion in gastroesophageal reflux disease. J Can Dent Assoc. 2003;69:84–9.PubMed Barron RP, Carmichael RP, Marcon MA, Sàndor GK. Dental erosion in gastroesophageal reflux disease. J Can Dent Assoc. 2003;69:84–9.PubMed
5.
Zurück zum Zitat Armstrong D, Bennett JR, Blum AL, et al. The endoscopic assessment of esophagitis: a progress report on observer agreement. Gastroenterology. 1996;111:85–92.CrossRefPubMed Armstrong D, Bennett JR, Blum AL, et al. The endoscopic assessment of esophagitis: a progress report on observer agreement. Gastroenterology. 1996;111:85–92.CrossRefPubMed
6.
Zurück zum Zitat Snaith RP. The hospital anxiety and depression scale. Health Qual Life Outcomes. 2003;1:29. Snaith RP. The hospital anxiety and depression scale. Health Qual Life Outcomes. 2003;1:29.
8.
Zurück zum Zitat Kitasako Y, Burrow MF, Stacey M, Huq L, Reynolds EC, Tagami J. Comparative analysis of three commercial saliva testing kits with a standard saliva buffering test. Aust Dent J. 2008;53:140–4.CrossRefPubMed Kitasako Y, Burrow MF, Stacey M, Huq L, Reynolds EC, Tagami J. Comparative analysis of three commercial saliva testing kits with a standard saliva buffering test. Aust Dent J. 2008;53:140–4.CrossRefPubMed
9.
Zurück zum Zitat Kumar S, Sharma S, Norboo T, et al. Population based study to assess prevalence and risk factors of gastroesophageal reflux disease in a high altitude area. Indian J Gastroenterol. 2011;30:135–43.CrossRefPubMed Kumar S, Sharma S, Norboo T, et al. Population based study to assess prevalence and risk factors of gastroesophageal reflux disease in a high altitude area. Indian J Gastroenterol. 2011;30:135–43.CrossRefPubMed
10.
Zurück zum Zitat Eisen GM, Sandler RS, Murray S, Gottfried M. The relationship between gastroesophageal reflux disease and its complications with Barrett’s esophagus. Am J Gastroenterol. 1997;92:27–31.PubMed Eisen GM, Sandler RS, Murray S, Gottfried M. The relationship between gastroesophageal reflux disease and its complications with Barrett’s esophagus. Am J Gastroenterol. 1997;92:27–31.PubMed
11.
Zurück zum Zitat Bansal A, Kahrilas PJ. Treatment of GERD complications (Barrett’s, peptic stricture) and extra-oesophageal syndromes. Best Pract Res Clin Gastroenterol. 2010;24:961–8.CrossRefPubMedPubMedCentral Bansal A, Kahrilas PJ. Treatment of GERD complications (Barrett’s, peptic stricture) and extra-oesophageal syndromes. Best Pract Res Clin Gastroenterol. 2010;24:961–8.CrossRefPubMedPubMedCentral
12.
Zurück zum Zitat Corrêa MC, Lerco MM, Cunha Mde L, Henry MA. Salivary parameters and teeth erosions in patients with gastroesophageal reflux disease. Arq Gastroenterol. 2012;49:214–8.CrossRefPubMed Corrêa MC, Lerco MM, Cunha Mde L, Henry MA. Salivary parameters and teeth erosions in patients with gastroesophageal reflux disease. Arq Gastroenterol. 2012;49:214–8.CrossRefPubMed
13.
Zurück zum Zitat Mota LAA, Santos ACO, Melo BC Jr, Travassos RO, Melo MSI. Videolaringoscopiae atividade da pepsina na saliva em voluntários com sintomas sugestivos de refluxo laringofaríngeo. Arq Int Otorrinolaringol. 2008;12:89–94. Mota LAA, Santos ACO, Melo BC Jr, Travassos RO, Melo MSI. Videolaringoscopiae atividade da pepsina na saliva em voluntários com sintomas sugestivos de refluxo laringofaríngeo. Arq Int Otorrinolaringol. 2008;12:89–94.
14.
Zurück zum Zitat Eckley CA, Costa HO. Estudo comparativo do pH e do volume salivar em indivíduos com laringofaringite crônica por doença do refluxo gastroesofágico antes e após tratamento. Rev Bras Otorrinolaringol. 2006;72:55–60.CrossRef Eckley CA, Costa HO. Estudo comparativo do pH e do volume salivar em indivíduos com laringofaringite crônica por doença do refluxo gastroesofágico antes e após tratamento. Rev Bras Otorrinolaringol. 2006;72:55–60.CrossRef
15.
Zurück zum Zitat Aframian DJ, Ofir M, Benoliel R. Comparison of oral mucosal pH values in bulimia nervosa, GERD, BMS patients and healthy population. Oral Dis. 2010;16:807–11.CrossRefPubMed Aframian DJ, Ofir M, Benoliel R. Comparison of oral mucosal pH values in bulimia nervosa, GERD, BMS patients and healthy population. Oral Dis. 2010;16:807–11.CrossRefPubMed
16.
Zurück zum Zitat Pace F, Pallotta S, Tonini M, Vakil N, Bianchi PG. Systematic review: gastro-oesophageal reflux disease and dental lesions. Aliment Pharmacol Ther. 2008;27:1179–86.CrossRefPubMed Pace F, Pallotta S, Tonini M, Vakil N, Bianchi PG. Systematic review: gastro-oesophageal reflux disease and dental lesions. Aliment Pharmacol Ther. 2008;27:1179–86.CrossRefPubMed
17.
Zurück zum Zitat Munoz JV, Herreros B, Sanchiz V, et al. Dental and periodontal lesions in patients with gastro-oesophageal reflux disease. Dig Liver Dis. 2003;35:461–7.CrossRefPubMed Munoz JV, Herreros B, Sanchiz V, et al. Dental and periodontal lesions in patients with gastro-oesophageal reflux disease. Dig Liver Dis. 2003;35:461–7.CrossRefPubMed
18.
Zurück zum Zitat Ersin NK, Onçağ O, Tümgör G, Aydoğdu S, Hilmioğlu S. Oral and dental manifestations of gastroesophageal reflux disease in children: a preliminary study. Pediatr Dent. 2006;28:279–84.PubMed Ersin NK, Onçağ O, Tümgör G, Aydoğdu S, Hilmioğlu S. Oral and dental manifestations of gastroesophageal reflux disease in children: a preliminary study. Pediatr Dent. 2006;28:279–84.PubMed
19.
Zurück zum Zitat Campisi G, Di Fede O, Roccia P, Di Nicola F, Falaschini S, Lo ML. Saliva: its value as biological matrix and current methods of sampling. Eur J Inflamm. 2006;4:11–9. Campisi G, Di Fede O, Roccia P, Di Nicola F, Falaschini S, Lo ML. Saliva: its value as biological matrix and current methods of sampling. Eur J Inflamm. 2006;4:11–9.
20.
Zurück zum Zitat Edgar WM. Saliva and dental health, clinical implications of saliva: report of a consensus meeting. Br Dent J. 1990;169:96–8.CrossRefPubMed Edgar WM. Saliva and dental health, clinical implications of saliva: report of a consensus meeting. Br Dent J. 1990;169:96–8.CrossRefPubMed
21.
Zurück zum Zitat Sun A, Wu KM, Wang YP, Lin HP, Chen HM, Chiang CP. Burning mouth syndrome: a review and update. J Oral Pathol Med. 2013;42:649–55.CrossRefPubMed Sun A, Wu KM, Wang YP, Lin HP, Chen HM, Chiang CP. Burning mouth syndrome: a review and update. J Oral Pathol Med. 2013;42:649–55.CrossRefPubMed
22.
Zurück zum Zitat Di Fede O, Di Liberto C, Occhipinti G, et al. Oral manifestations in patients with gastro-oesophageal reflux disease: a single-center case–control study. J Oral Pathol Med. 2008;37:336–40.CrossRefPubMed Di Fede O, Di Liberto C, Occhipinti G, et al. Oral manifestations in patients with gastro-oesophageal reflux disease: a single-center case–control study. J Oral Pathol Med. 2008;37:336–40.CrossRefPubMed
Metadaten
Titel
Oral pH in gastroesophageal reflux disease
verfasst von
S. Sujatha
Umesh Jalihal
Yashoda Devi
N. Rakesh
Pallavi Chauhan
Shivani Sharma
Publikationsdatum
23.05.2016
Verlag
Springer India
Erschienen in
Indian Journal of Gastroenterology / Ausgabe 3/2016
Print ISSN: 0254-8860
Elektronische ISSN: 0975-0711
DOI
https://doi.org/10.1007/s12664-016-0659-7

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