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Erschienen in: Surgery Today 7/2017

01.12.2016 | Original Article

Outcome and risk factors of recurrence after thoracoscopic bullectomy in young adults with primary spontaneous pneumothorax

verfasst von: Takashi Nakayama, Yusuke Takahashi, Hirofumi Uehara, Noriyuki Matsutani, Masafumi Kawamura

Erschienen in: Surgery Today | Ausgabe 7/2017

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Abstract

Purpose

To investigate the risk factors of recurrence of pneumothorax following thoracoscopic bullectomy in young adults.

Methods

Between January, 2005 and September, 2015, 167 patients aged ≤40 years underwent initial thoracoscopic bullectomy for primary spontaneous pneumothorax (PSP) at our hospital. Recurrence-free probability was calculated from the date of surgery to recurrence or last follow-up, using the Kaplan–Meier method.

Results

Sixteen (9.6%) of the 167 patients suffered a recurrence (collective total, 16 recurrences). The recurrence-free intervals were 3–107 months (median 25.8 months), and the 5-year recurrence-free probability was 85.9%. Multivariate Cox analysis demonstrated that age ≤23 years (p = 0.029) and a history of ipsilateral pneumothorax before surgery (p = 0.029) were significantly associated with higher risk of recurrence. The 5-year recurrence-free probability was 72.3% for patients aged ≤23 years and a history of ipsilateral pneumothorax before surgery and 94.1% for those with neither of these factors (p = 0.001). Recurrence developed within 3 years after surgery in 14 of the 16 patients.

Conclusions

Patients ≤23 years of age with a history of ipsilateral pneumothorax before surgery are at significantly high risk of its recurrence, frequently within 3 years; thus, the risk of postoperative recurrence of a pneumothorax must be kept in mind.
Literatur
1.
Zurück zum Zitat Sahn SA, Heffner JE. Spontaneous pneumothorax. N Engl J Med. 2000;23(342):868–74.CrossRef Sahn SA, Heffner JE. Spontaneous pneumothorax. N Engl J Med. 2000;23(342):868–74.CrossRef
2.
Zurück zum Zitat Zarogoulidis P, Kioumis I, Pitsiou G, Porpodis K, Lampaki S, Papaiwannou A, et al. Pneumothorax: from definition to diagnosis and treatment. J Thorac Dis. 2014;6(Suppl 4):S372–6.PubMedPubMedCentral Zarogoulidis P, Kioumis I, Pitsiou G, Porpodis K, Lampaki S, Papaiwannou A, et al. Pneumothorax: from definition to diagnosis and treatment. J Thorac Dis. 2014;6(Suppl 4):S372–6.PubMedPubMedCentral
4.
Zurück zum Zitat Santillan-Doherty P, Argote-Greene LM, Guzman-Sanchez M. Thoracoscopic management of primary spontaneous pneumothorax. Am Surg. 2006;72:145–9.PubMed Santillan-Doherty P, Argote-Greene LM, Guzman-Sanchez M. Thoracoscopic management of primary spontaneous pneumothorax. Am Surg. 2006;72:145–9.PubMed
5.
Zurück zum Zitat Barker A, Maratos EC, Edmonds L, Lim E. Recurrence rates of video-assisted thoracoscopic versus open surgery in the prevention of recurrent pneumothoraces: a systematic review of randomized and non-randomised trials. Lancet. 2007;370:329–35.CrossRefPubMed Barker A, Maratos EC, Edmonds L, Lim E. Recurrence rates of video-assisted thoracoscopic versus open surgery in the prevention of recurrent pneumothoraces: a systematic review of randomized and non-randomised trials. Lancet. 2007;370:329–35.CrossRefPubMed
6.
Zurück zum Zitat Muramatsu T, Nishii T, Takeshita S, Ishimoto S, Morooka H, Shiono M. Preventing recurrence of spontaneous pneumothorax after thoracoscopic surgery: a review of recent results. Surg Today. 2010;40:696–9.CrossRefPubMed Muramatsu T, Nishii T, Takeshita S, Ishimoto S, Morooka H, Shiono M. Preventing recurrence of spontaneous pneumothorax after thoracoscopic surgery: a review of recent results. Surg Today. 2010;40:696–9.CrossRefPubMed
7.
Zurück zum Zitat Sakamoto K, Takei H, Nishii T, Maehara T, Omori T, Tajiri M, et al. Staple line coverage with absorbable mesh after thoracoscopic bullectomy for spontaneous pneumothorax. Surg Endosc. 2004;18:478–81.CrossRefPubMed Sakamoto K, Takei H, Nishii T, Maehara T, Omori T, Tajiri M, et al. Staple line coverage with absorbable mesh after thoracoscopic bullectomy for spontaneous pneumothorax. Surg Endosc. 2004;18:478–81.CrossRefPubMed
8.
Zurück zum Zitat Lee S, Kim HR, Cho S, Huh DM, Lee EB, Ryu KM, et al. Staple line coverage after bullectomy for primary spontaneous pneumothorax: a randomized trial. Ann Thorac Surg. 2014;98:2005–11.CrossRefPubMed Lee S, Kim HR, Cho S, Huh DM, Lee EB, Ryu KM, et al. Staple line coverage after bullectomy for primary spontaneous pneumothorax: a randomized trial. Ann Thorac Surg. 2014;98:2005–11.CrossRefPubMed
9.
Zurück zum Zitat Casadio C, Rena O, Giobbe R, Rigoni R, Maggi G, Oliaro A. Stapler blebectomy and pleural abrasion by video-assisted thoracoscopy for spontaneous pneumothorax. J Cardiovasc Surg. 2002;43:259–62. Casadio C, Rena O, Giobbe R, Rigoni R, Maggi G, Oliaro A. Stapler blebectomy and pleural abrasion by video-assisted thoracoscopy for spontaneous pneumothorax. J Cardiovasc Surg. 2002;43:259–62.
10.
Zurück zum Zitat Herrmann D, Klapdor B, Ewig S, Hecker E. Initial management of primary spontaneous pneumothorax with video-assisted thoracoscopic surgery: a 10-year experience. Eur J Cardiothorac Surg. 2015;. doi:10.1093/ejcts/ezv206.PubMed Herrmann D, Klapdor B, Ewig S, Hecker E. Initial management of primary spontaneous pneumothorax with video-assisted thoracoscopic surgery: a 10-year experience. Eur J Cardiothorac Surg. 2015;. doi:10.​1093/​ejcts/​ezv206.PubMed
11.
Zurück zum Zitat Cutler SJ, Ederer F. Maximum utilization of the life table method in analyzing survival. J Chronic Dis. 1958;8:699–712.CrossRefPubMed Cutler SJ, Ederer F. Maximum utilization of the life table method in analyzing survival. J Chronic Dis. 1958;8:699–712.CrossRefPubMed
12.
Zurück zum Zitat Kennecke HF, Olivotto IA, Speers C, Norris B, Chia SK, Bryce C, et al. Late risk of relapse and mortality among postmenopausal women with estrogen responsive early breast cancer after 5 years of tamoxifen. Ann Oncol. 2007;18:45–51.CrossRefPubMed Kennecke HF, Olivotto IA, Speers C, Norris B, Chia SK, Bryce C, et al. Late risk of relapse and mortality among postmenopausal women with estrogen responsive early breast cancer after 5 years of tamoxifen. Ann Oncol. 2007;18:45–51.CrossRefPubMed
13.
Zurück zum Zitat Maeda R, Yoshida J, Ishii G, Aokage K, Hishida T, Nishimura M, et al. Long-term outcome and late recurrence in patients with completely resected stage IA non-small cell lung cancer. J Thorac Oncol. 2010;5:1246–50.CrossRefPubMed Maeda R, Yoshida J, Ishii G, Aokage K, Hishida T, Nishimura M, et al. Long-term outcome and late recurrence in patients with completely resected stage IA non-small cell lung cancer. J Thorac Oncol. 2010;5:1246–50.CrossRefPubMed
14.
Zurück zum Zitat Schramel FM, Postmus PE, Vanderschueren RG. Current aspects of spontaneous pneumothorax. Eur Respir J. 1997;10:1372–9.CrossRefPubMed Schramel FM, Postmus PE, Vanderschueren RG. Current aspects of spontaneous pneumothorax. Eur Respir J. 1997;10:1372–9.CrossRefPubMed
15.
Zurück zum Zitat Choi SY, Kim YH, Jo KH, Kim CK, Park JK, Cho DG, et al. Video-assisted thoracoscopic surgery for primary spontaneous pneumothorax in children. Pediatr Surg Int. 2013;29:505–9.CrossRefPubMed Choi SY, Kim YH, Jo KH, Kim CK, Park JK, Cho DG, et al. Video-assisted thoracoscopic surgery for primary spontaneous pneumothorax in children. Pediatr Surg Int. 2013;29:505–9.CrossRefPubMed
16.
Zurück zum Zitat West JB. Distribution of mechanical stress in the lung, a possible factor in localisation of pulmonary disease. Lancet. 1971;24(1):839–41.CrossRef West JB. Distribution of mechanical stress in the lung, a possible factor in localisation of pulmonary disease. Lancet. 1971;24(1):839–41.CrossRef
17.
Zurück zum Zitat Moriyama S, Okutani D. Analysis of risk factors of recurrence of primary spontaneous pneumothorax (in Japanese with English abstract). Nihon Kikyo Nouhousei Haisikkann Gakkaizasshi (J Jpn Soc Pneumothorax Cystic Lung Dis). 2010; 10:96–100. Moriyama S, Okutani D. Analysis of risk factors of recurrence of primary spontaneous pneumothorax (in Japanese with English abstract). Nihon Kikyo Nouhousei Haisikkann Gakkaizasshi (J Jpn Soc Pneumothorax Cystic Lung Dis). 2010; 10:96–100.
18.
Zurück zum Zitat Tschopp JM, Bintcliffe O, Astoul P, Canalis E, Driesen P, Janssen J, et al. ERS task force statement: diagnosis and treatment of primary spontaneous pneumothorax. Eur Respir J. 2015;46:321–35.CrossRefPubMed Tschopp JM, Bintcliffe O, Astoul P, Canalis E, Driesen P, Janssen J, et al. ERS task force statement: diagnosis and treatment of primary spontaneous pneumothorax. Eur Respir J. 2015;46:321–35.CrossRefPubMed
19.
Zurück zum Zitat Huang TW, Lee SC, Cheng YL, Tzao C, Hsu HH, Chang H, et al. Contralateral recurrence of primary spontaneous pneumothorax. Chest. 2007;132:1146–50.CrossRefPubMed Huang TW, Lee SC, Cheng YL, Tzao C, Hsu HH, Chang H, et al. Contralateral recurrence of primary spontaneous pneumothorax. Chest. 2007;132:1146–50.CrossRefPubMed
20.
Zurück zum Zitat Imperatori A, Rotolo N, Spagnoletti M, Festi L, Berizzi F, Di Natale D, et al. Risk factors for postoperative recurrence of spontaneous pneumothorax treated by video-assisted thoracoscopic surgerydagger. Interact CardioVasc Thorac Surg. 2015;20:647–52.CrossRefPubMed Imperatori A, Rotolo N, Spagnoletti M, Festi L, Berizzi F, Di Natale D, et al. Risk factors for postoperative recurrence of spontaneous pneumothorax treated by video-assisted thoracoscopic surgerydagger. Interact CardioVasc Thorac Surg. 2015;20:647–52.CrossRefPubMed
21.
Zurück zum Zitat Min X, Huang Y, Yang Y, Chen Y, Cui J, Wang C, et al. Mechanical pleurodesis does not reduce recurrence of spontaneous pneumothorax: a randomized trial. Ann Thorac Surg. 2014;98:1790–6.CrossRefPubMed Min X, Huang Y, Yang Y, Chen Y, Cui J, Wang C, et al. Mechanical pleurodesis does not reduce recurrence of spontaneous pneumothorax: a randomized trial. Ann Thorac Surg. 2014;98:1790–6.CrossRefPubMed
Metadaten
Titel
Outcome and risk factors of recurrence after thoracoscopic bullectomy in young adults with primary spontaneous pneumothorax
verfasst von
Takashi Nakayama
Yusuke Takahashi
Hirofumi Uehara
Noriyuki Matsutani
Masafumi Kawamura
Publikationsdatum
01.12.2016
Verlag
Springer Japan
Erschienen in
Surgery Today / Ausgabe 7/2017
Print ISSN: 0941-1291
Elektronische ISSN: 1436-2813
DOI
https://doi.org/10.1007/s00595-016-1452-z

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