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Erschienen in: Langenbeck's Archives of Surgery 6/2012

01.08.2012 | Original Article

Outcome in patients with long-term treatment in a surgical intensive care unit

verfasst von: Nina Weiler, Jens Waldmann, Detlef K. Bartsch, Caroline Rolfes, Volker Fendrich

Erschienen in: Langenbeck's Archives of Surgery | Ausgabe 6/2012

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Abstract

Background

This study aimed to evaluate the outcome of patients with abdominal, thoracic or vascular operations and long-term intensive care unit (ICU) treatment.

Patients and methods

The present retrospective observational cohort study was performed at the authors' surgical ICU at the Marburg University Medical Centre. All patients who stayed at the ICU longer than 48 h and underwent visceral, thoracic or vascular surgery between January 2005 and December 2006 were retrospectively analysed. Patients with an ICU stay of 20 or more days were defined as the long-term study group. Clinical variables were tested for prognostic value.

Results

In 2 years, 852 patients were treated at the intensive care unit. Follow-up was available in 502 patients, with 219 patients treated for two and more days and a median of 16.4 days. Sixty-seven long-term patients were compared to 152 (69.4 %) patients treated between 2 and 20 days. Overall survival after 12 months was 50.2 % (110/219), while 65.8 % (144/219) were discharged from ICU.
Older age, longer treatment at the ICU and increased simplified acute physiology score (SAPS) at admission were associated with decreased 12-month survival, while no statistical differences were observed for the underlying and malignant disease by univariate analysis.
The risk of death was 29, 56 and 61 % for patients treated 2–4, 5–19 and ≥20 days at the ICU. Decreased survival of patients treated for 5–19 and ≥20 days were confirmed by logrank test (p = 0.001).

Conclusions

Patients with long-term ICU stay showed decreased survival than patients who are treated less than 5 days but similar survival as patients which stayed between 5 and 19 days. Malignant disease is not associated with an unfavourable 12-month survival while older age, higher SAPS index at discharge and longer stay at ICU are. Long-term ICU survivors have no increased risk to succumb after discharge from ICU.
Literatur
1.
Zurück zum Zitat Die Gesundheitsberichterstattung des Bundes. In: Gesundheitsversorgung. 2011, Statistisches Bundesamt: Bonn Die Gesundheitsberichterstattung des Bundes. In: Gesundheitsversorgung. 2011, Statistisches Bundesamt: Bonn
2.
Zurück zum Zitat Jakob SM, Rothen HU (1997) Intensive care 1980–1995: change in patient characteristics, nursing workload and outcome. Intensive Care Med 23(11):1165–1170PubMedCrossRef Jakob SM, Rothen HU (1997) Intensive care 1980–1995: change in patient characteristics, nursing workload and outcome. Intensive Care Med 23(11):1165–1170PubMedCrossRef
3.
Zurück zum Zitat Groeger JS et al (1993) Descriptive analysis of critical care units in the United States: patient characteristics and intensive care unit utilization. Crit Care Med 21(2):279–291PubMedCrossRef Groeger JS et al (1993) Descriptive analysis of critical care units in the United States: patient characteristics and intensive care unit utilization. Crit Care Med 21(2):279–291PubMedCrossRef
4.
Zurück zum Zitat Levine WC, Mehta V, Landesberg G (2006) Anesthesia for the elderly: selected topics. Curr Opin Anaesthesiol 19(3):320–324PubMedCrossRef Levine WC, Mehta V, Landesberg G (2006) Anesthesia for the elderly: selected topics. Curr Opin Anaesthesiol 19(3):320–324PubMedCrossRef
5.
Zurück zum Zitat Petrowsky H, Clavien PA (2005) Should we deny surgery for malignant hepato-pancreatico-biliary tumors to elderly patients? World J Surg 29(9):1093–1100PubMedCrossRef Petrowsky H, Clavien PA (2005) Should we deny surgery for malignant hepato-pancreatico-biliary tumors to elderly patients? World J Surg 29(9):1093–1100PubMedCrossRef
6.
Zurück zum Zitat Sgourakis G et al (2009) Major liver resections for primary liver malignancies in the elderly. Acta Chir Belg 109(3):340–344PubMed Sgourakis G et al (2009) Major liver resections for primary liver malignancies in the elderly. Acta Chir Belg 109(3):340–344PubMed
7.
Zurück zum Zitat Pultrum BB et al (2010) Extended esophagectomy in elderly patients with esophageal cancer: minor effect of age alone in determining the postoperative course and survival. Ann Surg Oncol 17(6):1572–1580PubMedCrossRef Pultrum BB et al (2010) Extended esophagectomy in elderly patients with esophageal cancer: minor effect of age alone in determining the postoperative course and survival. Ann Surg Oncol 17(6):1572–1580PubMedCrossRef
8.
Zurück zum Zitat Ibis C et al (2010) The amount of comorbidities as a single parameter has no effect in predicting the outcome in appendicitis patients older than 60 years. South Med J 103(3):202–206PubMedCrossRef Ibis C et al (2010) The amount of comorbidities as a single parameter has no effect in predicting the outcome in appendicitis patients older than 60 years. South Med J 103(3):202–206PubMedCrossRef
9.
Zurück zum Zitat Le Gall JR et al (1982) Influence of age, previous health status, and severity of acute illness on outcome from intensive care. Crit Care Med 10(9):575–577PubMedCrossRef Le Gall JR et al (1982) Influence of age, previous health status, and severity of acute illness on outcome from intensive care. Crit Care Med 10(9):575–577PubMedCrossRef
10.
Zurück zum Zitat Thibault GE et al (1980) Medical intensive care: indications, interventions, and outcomes. N Engl J Med 302(17):938–942PubMedCrossRef Thibault GE et al (1980) Medical intensive care: indications, interventions, and outcomes. N Engl J Med 302(17):938–942PubMedCrossRef
11.
Zurück zum Zitat Montuclard L et al (2000) Outcome, functional autonomy, and quality of life of elderly patients with a long-term intensive care unit stay. Crit Care Med 28(10):3389–3395PubMedCrossRef Montuclard L et al (2000) Outcome, functional autonomy, and quality of life of elderly patients with a long-term intensive care unit stay. Crit Care Med 28(10):3389–3395PubMedCrossRef
12.
Zurück zum Zitat Wolkewitz M et al (2008) Risk factors for the development of nosocomial pneumonia and mortality on intensive care units: application of competing risks models. Crit Care 12(2):R44PubMedCrossRef Wolkewitz M et al (2008) Risk factors for the development of nosocomial pneumonia and mortality on intensive care units: application of competing risks models. Crit Care 12(2):R44PubMedCrossRef
13.
Zurück zum Zitat Soares M et al (2008) Short- and long-term outcomes of critically ill patients with cancer and prolonged ICU length of stay. Chest 134(3):520–526PubMedCrossRef Soares M et al (2008) Short- and long-term outcomes of critically ill patients with cancer and prolonged ICU length of stay. Chest 134(3):520–526PubMedCrossRef
14.
Zurück zum Zitat Rimachi R, Vincent JL, Brimioulle S (2007) Survival and quality of life after prolonged intensive care unit stay. Anaesth Intensive Care 35(1):62–67PubMed Rimachi R, Vincent JL, Brimioulle S (2007) Survival and quality of life after prolonged intensive care unit stay. Anaesth Intensive Care 35(1):62–67PubMed
15.
Zurück zum Zitat Friedrich JO, Wilson G, Chant C (2006) Long-term outcomes and clinical predictors of hospital mortality in very long stay intensive care unit patients: a cohort study. Crit Care 10(2):R59PubMedCrossRef Friedrich JO, Wilson G, Chant C (2006) Long-term outcomes and clinical predictors of hospital mortality in very long stay intensive care unit patients: a cohort study. Crit Care 10(2):R59PubMedCrossRef
16.
Zurück zum Zitat Heimrath OP, Buth KJ, Legare JF (2007) Long-term outcomes in patients requiring stay of more than 48 hours in the intensive care unit following coronary bypass surgery. J Crit Care 22(2):153–158PubMedCrossRef Heimrath OP, Buth KJ, Legare JF (2007) Long-term outcomes in patients requiring stay of more than 48 hours in the intensive care unit following coronary bypass surgery. J Crit Care 22(2):153–158PubMedCrossRef
17.
Zurück zum Zitat Hein OV et al (2006) Prolonged intensive care unit stay in cardiac surgery: risk factors and long-term-survival. Ann Thorac Surg 81(3):880–885PubMedCrossRef Hein OV et al (2006) Prolonged intensive care unit stay in cardiac surgery: risk factors and long-term-survival. Ann Thorac Surg 81(3):880–885PubMedCrossRef
18.
Zurück zum Zitat De Maria R et al (2005) Predictive value of EuroSCORE on long term outcome in cardiac surgery patients: a single institution study. Heart 91(6):779–784PubMedCrossRef De Maria R et al (2005) Predictive value of EuroSCORE on long term outcome in cardiac surgery patients: a single institution study. Heart 91(6):779–784PubMedCrossRef
19.
Zurück zum Zitat Messaoudi N et al (2009) Prediction of prolonged length of stay in the intensive care unit after cardiac surgery: the need for a multi-institutional risk scoring system. J Card Surg 24(2):127–133PubMedCrossRef Messaoudi N et al (2009) Prediction of prolonged length of stay in the intensive care unit after cardiac surgery: the need for a multi-institutional risk scoring system. J Card Surg 24(2):127–133PubMedCrossRef
20.
Zurück zum Zitat Atoui R et al (2008) Risk factors for prolonged stay in the intensive care unit and on the ward after cardiac surgery. J Card Surg 23(2):99–106PubMedCrossRef Atoui R et al (2008) Risk factors for prolonged stay in the intensive care unit and on the ward after cardiac surgery. J Card Surg 23(2):99–106PubMedCrossRef
21.
Zurück zum Zitat Xu J et al (2007) A simple predictive model of prolonged intensive care unit stay after surgery for acquired heart valve disease. J Heart Valve Dis 16(2):109–115PubMed Xu J et al (2007) A simple predictive model of prolonged intensive care unit stay after surgery for acquired heart valve disease. J Heart Valve Dis 16(2):109–115PubMed
22.
Zurück zum Zitat Hartl WH et al (2007) Acute and long-term survival in chronically critically ill surgical patients: a retrospective observational study. Crit Care 11(3):R55PubMedCrossRef Hartl WH et al (2007) Acute and long-term survival in chronically critically ill surgical patients: a retrospective observational study. Crit Care 11(3):R55PubMedCrossRef
23.
Zurück zum Zitat Merlani P et al (2007) Long-term outcome of elderly patients requiring intensive care admission for abdominal pathologies: survival and quality of life. Acta Anaesthesiol Scand 51(5):530–537PubMedCrossRef Merlani P et al (2007) Long-term outcome of elderly patients requiring intensive care admission for abdominal pathologies: survival and quality of life. Acta Anaesthesiol Scand 51(5):530–537PubMedCrossRef
24.
Zurück zum Zitat Darmon M, Azoulay E (2009) Critical care management of cancer patients: cause for optimism and need for objectivity. Curr Opin Oncol 21(4):318–326PubMedCrossRef Darmon M, Azoulay E (2009) Critical care management of cancer patients: cause for optimism and need for objectivity. Curr Opin Oncol 21(4):318–326PubMedCrossRef
25.
Zurück zum Zitat Bashour CA et al (2000) Long-term survival and functional capacity in cardiac surgery patients after prolonged intensive care. Crit Care Med 28(12):3847–3853PubMedCrossRef Bashour CA et al (2000) Long-term survival and functional capacity in cardiac surgery patients after prolonged intensive care. Crit Care Med 28(12):3847–3853PubMedCrossRef
26.
Zurück zum Zitat Wong DT et al (1999) Utilization of intensive care unit days in a Canadian medical-surgical intensive care unit. Crit Care Med 27(7):1319–1324PubMedCrossRef Wong DT et al (1999) Utilization of intensive care unit days in a Canadian medical-surgical intensive care unit. Crit Care Med 27(7):1319–1324PubMedCrossRef
27.
Zurück zum Zitat Bickenbach J et al (2011) Outcome and mortality risk factors in long-term treated ICU patients: a retrospective analysis. Minerva Anestesiol 77(4):427–438PubMed Bickenbach J et al (2011) Outcome and mortality risk factors in long-term treated ICU patients: a retrospective analysis. Minerva Anestesiol 77(4):427–438PubMed
28.
Zurück zum Zitat Hein OV et al (2006) Intensive care unit stay of more than 14 days after cardiac surgery is associated with non-cardiac organ failure. J Int Med Res 34(6):695–703PubMed Hein OV et al (2006) Intensive care unit stay of more than 14 days after cardiac surgery is associated with non-cardiac organ failure. J Int Med Res 34(6):695–703PubMed
29.
Zurück zum Zitat Laupland KB et al (2006) Long-term mortality outcome associated with prolonged admission to the ICU. Chest 129(4):954–959PubMedCrossRef Laupland KB et al (2006) Long-term mortality outcome associated with prolonged admission to the ICU. Chest 129(4):954–959PubMedCrossRef
30.
Zurück zum Zitat Williams TA et al (2008) Determinants of long-term survival after intensive care. Crit Care Med 36(5):1523–1530PubMedCrossRef Williams TA et al (2008) Determinants of long-term survival after intensive care. Crit Care Med 36(5):1523–1530PubMedCrossRef
31.
Zurück zum Zitat Gersbach P et al (2006) Are there accurate predictors of long-term vital and functional outcomes in cardiac surgical patients requiring prolonged intensive care? Eur J Cardiothorac Surg 29(4):466–472PubMedCrossRef Gersbach P et al (2006) Are there accurate predictors of long-term vital and functional outcomes in cardiac surgical patients requiring prolonged intensive care? Eur J Cardiothorac Surg 29(4):466–472PubMedCrossRef
Metadaten
Titel
Outcome in patients with long-term treatment in a surgical intensive care unit
verfasst von
Nina Weiler
Jens Waldmann
Detlef K. Bartsch
Caroline Rolfes
Volker Fendrich
Publikationsdatum
01.08.2012
Verlag
Springer-Verlag
Erschienen in
Langenbeck's Archives of Surgery / Ausgabe 6/2012
Print ISSN: 1435-2443
Elektronische ISSN: 1435-2451
DOI
https://doi.org/10.1007/s00423-012-0966-0

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