Skip to main content
Erschienen in: European Spine Journal 1/2006

01.01.2006 | Review

Outcome of invasive treatment modalities on back pain and sciatica: an evidence-based review

verfasst von: Maurits W. van Tulder, Bart Koes, Seppo Seitsalo, Antti Malmivaara

Erschienen in: European Spine Journal | Sonderheft 1/2006

Einloggen, um Zugang zu erhalten

Abstract

Within the framework of evidence-based medicine high-quality randomised trials and systematic reviews are considered a necessary prerequisite for progress in orthopaedics. This paper summarises the currently available evidence on surgical and other invasive procedures for low back pain. Results of systematic reviews conducted within the framework of the Cochrane Back Review Group were used. Data were gathered from the latest Cochrane Database of Systematic Reviews 2005, Issue 2. The Cochrane reviews were updated using the evidence summary on surgery and other invasive procedures from the COST B13 European Guidelines for the Management of Acute and Chronic Non-Specific Low Back Pain. Facet joint, epidural, trigger point and sclerosant injections have not clearly been shown to be effective and can consequently not be recommended. There is no scientific evidence on the effectiveness of spinal stenosis surgery. Surgical discectomy may be considered for selected patients with sciatica due to lumbar disc prolapses that fail to resolve with the conservative management. Cognitive intervention Combined with exercises is recommended for chronic low back pain, and fusion surgery may be considered only in carefully selected patients after active rehabilitation programmes during 2 years time have failed. Demanding surgical fusion techniques are not better than the traditional posterolateral fusion without internal fixation.
Literatur
1.
Zurück zum Zitat Amundsen T, Weber H, Nordal HJ, Magnaes B, Abdelnoor M, Lilleas F (2000) Lumbar spinal stenosis: conservative or surgical management? A prospective 10-year study. Spine 25:1424–1435PubMedCrossRef Amundsen T, Weber H, Nordal HJ, Magnaes B, Abdelnoor M, Lilleas F (2000) Lumbar spinal stenosis: conservative or surgical management? A prospective 10-year study. Spine 25:1424–1435PubMedCrossRef
2.
Zurück zum Zitat Barendse GAM, van den Berg SGM, Kessels AHF, Weber WEJ, van Kleef M (2001) Randomized controlled trial of percutaneous intradiscal radiofrequency thermocoagulation for chronic discogenic back pain: lack of effect from a 90-second 70 C lesion. Spine 26:287–292PubMedCrossRef Barendse GAM, van den Berg SGM, Kessels AHF, Weber WEJ, van Kleef M (2001) Randomized controlled trial of percutaneous intradiscal radiofrequency thermocoagulation for chronic discogenic back pain: lack of effect from a 90-second 70 C lesion. Spine 26:287–292PubMedCrossRef
3.
Zurück zum Zitat Béliveau P (1971) A comparison between epidural anaesthesia with and without corticosteroid in the treatment of sciatica. Rheumatol Phys Med 11:40–43PubMedCrossRef Béliveau P (1971) A comparison between epidural anaesthesia with and without corticosteroid in the treatment of sciatica. Rheumatol Phys Med 11:40–43PubMedCrossRef
4.
Zurück zum Zitat Benoist M, Bonneville JF, Lassale B, Runge M, Gillard C, Vazquez Suarez J, Deburge A (1993) A randomized, double-blind study to compare low-dose with standard-dose chymopapain in the treatment of herniated lumbar intervertebral discs. Spine 18:28–34PubMedCrossRef Benoist M, Bonneville JF, Lassale B, Runge M, Gillard C, Vazquez Suarez J, Deburge A (1993) A randomized, double-blind study to compare low-dose with standard-dose chymopapain in the treatment of herniated lumbar intervertebral discs. Spine 18:28–34PubMedCrossRef
5.
Zurück zum Zitat Bontoux D, Alcalay M, Debiais F, Garrouste O, Ingrand P, Azais I, Roualdes G (1990) Treatment of lumbar disk hernia by intra-disk injection of chymopapain or triamcinolone hexacetonide. Comparative study of 80 cases [Traitement des hernies discales lombaires par injection intradiscale de chymopapaine ou d’hexacetonide de triamcinolone. Etude comparee de 80 cas]. Rev Rhum Mal Osteoartic 57:327–331PubMed Bontoux D, Alcalay M, Debiais F, Garrouste O, Ingrand P, Azais I, Roualdes G (1990) Treatment of lumbar disk hernia by intra-disk injection of chymopapain or triamcinolone hexacetonide. Comparative study of 80 cases [Traitement des hernies discales lombaires par injection intradiscale de chymopapaine ou d’hexacetonide de triamcinolone. Etude comparee de 80 cas]. Rev Rhum Mal Osteoartic 57:327–331PubMed
6.
Zurück zum Zitat Bourgeois P, Benoist M, Palazzo E, Belmatoug N, Folinais D, Frot B, Busson G, Lassale P, Montagner C, Binoche T (1988) Multicenter randomized double-blind study of triamcinolone hexacetonide versus chymopapain in the treatment of disk lumbosciatica. Initial results at 6 months [Etude en double aveugle randomisee multicentrique de l’hexacetonide de triamcinolone versus chymopapaine dans le traitement de la lombosciatique discale. Premiers resultats a six mois]. Rev Rhum Mal Osteoartic 55:767–769PubMed Bourgeois P, Benoist M, Palazzo E, Belmatoug N, Folinais D, Frot B, Busson G, Lassale P, Montagner C, Binoche T (1988) Multicenter randomized double-blind study of triamcinolone hexacetonide versus chymopapain in the treatment of disk lumbosciatica. Initial results at 6 months [Etude en double aveugle randomisee multicentrique de l’hexacetonide de triamcinolone versus chymopapaine dans le traitement de la lombosciatique discale. Premiers resultats a six mois]. Rev Rhum Mal Osteoartic 55:767–769PubMed
7.
Zurück zum Zitat Bouter LM, Pennick V, Bombardier C, Editorial Board of the Back Review Group (2003) Cochrane Back Review Group. Spine 28:1215–1218PubMedCrossRef Bouter LM, Pennick V, Bombardier C, Editorial Board of the Back Review Group (2003) Cochrane Back Review Group. Spine 28:1215–1218PubMedCrossRef
8.
Zurück zum Zitat Breivik H, Hesla PE, Molnar I, Lind B (1976) Treatment of chronic low back pain and sciatica: comparison of caudal epidural injections of bupivacaine and methylprednisolone with bupibvacaine followed by saline. Adv Pain Res Ther 1:927–932 Breivik H, Hesla PE, Molnar I, Lind B (1976) Treatment of chronic low back pain and sciatica: comparison of caudal epidural injections of bupivacaine and methylprednisolone with bupibvacaine followed by saline. Adv Pain Res Ther 1:927–932
9.
Zurück zum Zitat Bridwell KH, Sedgewick TA, O’Brien MF, Lenke LG, Baldus C (1993) The role of fusion and instrumentation in the treatment of degenerative spondylolisthesis with spinal stenosis. J Spinal Disord 6:461–472PubMed Bridwell KH, Sedgewick TA, O’Brien MF, Lenke LG, Baldus C (1993) The role of fusion and instrumentation in the treatment of degenerative spondylolisthesis with spinal stenosis. J Spinal Disord 6:461–472PubMed
10.
Zurück zum Zitat Bromley JW, Varma AO, Santoro AJ, Cohen P, Jacobs R, Berger L (1984) Double-blind evaluation of collagenase injections for herniated lumbar discs. Spine 9:486–488PubMedCrossRef Bromley JW, Varma AO, Santoro AJ, Cohen P, Jacobs R, Berger L (1984) Double-blind evaluation of collagenase injections for herniated lumbar discs. Spine 9:486–488PubMedCrossRef
11.
Zurück zum Zitat Brox JI, Sorensen R, Friis A, Nygaard O, Indahl A, Keller A, Ingebrigtsen T, Eriksen HR, Holm I, Koller AK, Riise R, Reikeras O (2003) Randomized clinical trial of lumbar instrumented fusion and cognitive intervention and exercises in patients with chronic low back pain and disc degeneration. Spine 28:1913–1921PubMedCrossRef Brox JI, Sorensen R, Friis A, Nygaard O, Indahl A, Keller A, Ingebrigtsen T, Eriksen HR, Holm I, Koller AK, Riise R, Reikeras O (2003) Randomized clinical trial of lumbar instrumented fusion and cognitive intervention and exercises in patients with chronic low back pain and disc degeneration. Spine 28:1913–1921PubMedCrossRef
12.
Zurück zum Zitat Bush K, Hillier S (1991) A controlled study of caudal epidural injections of triamcinolone plus procaine for the management of intractable sciatica. Spine 15:572–575CrossRef Bush K, Hillier S (1991) A controlled study of caudal epidural injections of triamcinolone plus procaine for the management of intractable sciatica. Spine 15:572–575CrossRef
13.
Zurück zum Zitat Carragee EJ (1997) Single-level posterolateral arthrodesis, with or without posterior decompression, for the treatment of isthmic spondylolisthesis in adults. A prospective, randomised study. J Bone Joint Surg 79A:1175–1180 Carragee EJ (1997) Single-level posterolateral arthrodesis, with or without posterior decompression, for the treatment of isthmic spondylolisthesis in adults. A prospective, randomised study. J Bone Joint Surg 79A:1175–1180
14.
Zurück zum Zitat Carette S, Marcoux S, Truchon R, Grondin C, Gagnon J, Allard Y, Latulippe M (1991) A controlled trial of corticosteroid injections into facet joints for chronic low back pain. New Engl J Med 325:1002–1007PubMed Carette S, Marcoux S, Truchon R, Grondin C, Gagnon J, Allard Y, Latulippe M (1991) A controlled trial of corticosteroid injections into facet joints for chronic low back pain. New Engl J Med 325:1002–1007PubMed
15.
Zurück zum Zitat Carette S, Leclaire R, Marcoux S (1997) Epidural corticosteroid injections for sciatica due to herniated nucleus pulposus. New Engl J Med 336:1634–1640PubMedCrossRef Carette S, Leclaire R, Marcoux S (1997) Epidural corticosteroid injections for sciatica due to herniated nucleus pulposus. New Engl J Med 336:1634–1640PubMedCrossRef
16.
Zurück zum Zitat Chatterjee S, Foy PM, Findlay GF (1995) Report of a controlled clinical trial comparing automated percutaneous lumbar discectomy and microdiscectomy in the treatment of contained lumbar disc herniation. Spine 20:734–738PubMedCrossRef Chatterjee S, Foy PM, Findlay GF (1995) Report of a controlled clinical trial comparing automated percutaneous lumbar discectomy and microdiscectomy in the treatment of contained lumbar disc herniation. Spine 20:734–738PubMedCrossRef
17.
Zurück zum Zitat Christensen FB, Hansen ES, Eiskjaer SP, Hoy K, Helmig P, Neumann P, Niedermann B, Bunger CE (2002) Circumferential lumbar spinal fusion with ALIF Brantigan cage versus posterolateral fusion with titanium CD-Horizon: a prospective, randomized, clinical study of 146 patients. Spine 27:2674–2683PubMedCrossRef Christensen FB, Hansen ES, Eiskjaer SP, Hoy K, Helmig P, Neumann P, Niedermann B, Bunger CE (2002) Circumferential lumbar spinal fusion with ALIF Brantigan cage versus posterolateral fusion with titanium CD-Horizon: a prospective, randomized, clinical study of 146 patients. Spine 27:2674–2683PubMedCrossRef
18.
Zurück zum Zitat Collée G, Dijkmans BAC, Vandenbroucke JP, Cats A (1991) lliac crest pain syndrome in low back pain. A double blind, randomized study of local injection therapy. J Rheumatol 18:1060–1063PubMed Collée G, Dijkmans BAC, Vandenbroucke JP, Cats A (1991) lliac crest pain syndrome in low back pain. A double blind, randomized study of local injection therapy. J Rheumatol 18:1060–1063PubMed
19.
Zurück zum Zitat Crawshaw C, Frazer AM, Merriam WF, Mulholland RC, Webb JK (1984) A comparison of surgery and chemonucleolysis in the treatment of sciatica. A prospective randomized trial. Spine 9:195–198PubMedCrossRef Crawshaw C, Frazer AM, Merriam WF, Mulholland RC, Webb JK (1984) A comparison of surgery and chemonucleolysis in the treatment of sciatica. A prospective randomized trial. Spine 9:195–198PubMedCrossRef
20.
Zurück zum Zitat Cuckler JM, Bernini PA, Wiesel SW, Booth RE, Rothman RH, Pickens GT (1985) The use of epidural steroids in the treatment of lumbar radicular pain. J Bone Joint Surg 67A:63–66 Cuckler JM, Bernini PA, Wiesel SW, Booth RE, Rothman RH, Pickens GT (1985) The use of epidural steroids in the treatment of lumbar radicular pain. J Bone Joint Surg 67A:63–66
21.
Zurück zum Zitat Dabezies EJ, Langford K, Morris J, Shields CB, Wilkinson HA (1988) Safety and efficacy of chymopapain (Discase) in the treatment of sciatica due to a herniated nucleus pulposus. Results of a randomized, double-blind study. Spine 13:561–565PubMedCrossRef Dabezies EJ, Langford K, Morris J, Shields CB, Wilkinson HA (1988) Safety and efficacy of chymopapain (Discase) in the treatment of sciatica due to a herniated nucleus pulposus. Results of a randomized, double-blind study. Spine 13:561–565PubMedCrossRef
22.
Zurück zum Zitat Dallas TL, Lin RL, Wu WH, Wolskee P (1987) Epidural morphine and methylprednisolone for low-back pain. Anaesthesiology 67:408–411CrossRef Dallas TL, Lin RL, Wu WH, Wolskee P (1987) Epidural morphine and methylprednisolone for low-back pain. Anaesthesiology 67:408–411CrossRef
23.
Zurück zum Zitat Dechow E, Davies RK, Carr AJ, Thompson PW (1999) A randomized, double-blind, placebo-controlled trial of sclerosing injections in patients with chronic low back pain. Rheumatology (Oxford) 38:1255–1259CrossRef Dechow E, Davies RK, Carr AJ, Thompson PW (1999) A randomized, double-blind, placebo-controlled trial of sclerosing injections in patients with chronic low back pain. Rheumatology (Oxford) 38:1255–1259CrossRef
24.
Zurück zum Zitat Ejeskar A, Nachemson A, Herberts P, Lysell E, Andersson G, Irstam L, Peterson LE (1983) Surgery versus chemonucleolysis for herniated lumbar discs. A prospective study with random assignment. Clin Orthop 174:236–242PubMed Ejeskar A, Nachemson A, Herberts P, Lysell E, Andersson G, Irstam L, Peterson LE (1983) Surgery versus chemonucleolysis for herniated lumbar discs. A prospective study with random assignment. Clin Orthop 174:236–242PubMed
25.
Zurück zum Zitat Fairbank J (1999) Spine update: randomized controlled trials in the surgical management of spinal problems. Spine 24:25–56CrossRef Fairbank J (1999) Spine update: randomized controlled trials in the surgical management of spinal problems. Spine 24:25–56CrossRef
26.
Zurück zum Zitat Fairbank JC, Frost H, Wilson-MacDonald J, Yu LM, Barker K, Collins R (2005) Randomised controlled trial to compare surgical stabilisation of the lumbar spine with an intensive rehabilitation programme for patients with chronic low back pain: the MRC spine stabilisation trial. BMJ 330:1233PubMedCrossRef Fairbank JC, Frost H, Wilson-MacDonald J, Yu LM, Barker K, Collins R (2005) Randomised controlled trial to compare surgical stabilisation of the lumbar spine with an intensive rehabilitation programme for patients with chronic low back pain: the MRC spine stabilisation trial. BMJ 330:1233PubMedCrossRef
27.
Zurück zum Zitat Feldman J, Menkes CJ, Pallardy G, Chevrot A, Horreard P, Zenny JC, Godefroy D, Amor B (1986) Double-blind study of the treatment of disc lumbosciatica by chemonucleolysis [Etude en double-aveugle du traitement de la lombosciatique discale par chimionucleolyse]. Rev Rhum Mal Osteoartic 53:147–152PubMed Feldman J, Menkes CJ, Pallardy G, Chevrot A, Horreard P, Zenny JC, Godefroy D, Amor B (1986) Double-blind study of the treatment of disc lumbosciatica by chemonucleolysis [Etude en double-aveugle du traitement de la lombosciatique discale par chimionucleolyse]. Rev Rhum Mal Osteoartic 53:147–152PubMed
28.
Zurück zum Zitat Fischgrund JS, Mackay M, Herkowitz HN, Brower R, Montgomery DM, Kurz LT (1997) Degenerative lumbar spondylolisthesis with spinal stenosis: a prospective, randomized study comparing decompressive laminectomy and arthrodesis with and without spinal instrumentation. Spine 22:2807–2812PubMedCrossRef Fischgrund JS, Mackay M, Herkowitz HN, Brower R, Montgomery DM, Kurz LT (1997) Degenerative lumbar spondylolisthesis with spinal stenosis: a prospective, randomized study comparing decompressive laminectomy and arthrodesis with and without spinal instrumentation. Spine 22:2807–2812PubMedCrossRef
29.
Zurück zum Zitat France JC, Yaszemski MJ, Lauerman WC, Cain JE, Glover JM, Lawson KJ, Coe JD, Topper SM (1999) A randomized prospective study of posterolateral lumbar fusion: outcomes with and without pedicle screw instrumentation. Spine 24:553–560PubMedCrossRef France JC, Yaszemski MJ, Lauerman WC, Cain JE, Glover JM, Lawson KJ, Coe JD, Topper SM (1999) A randomized prospective study of posterolateral lumbar fusion: outcomes with and without pedicle screw instrumentation. Spine 24:553–560PubMedCrossRef
30.
Zurück zum Zitat Fraser RD (1982) Chymopapain for the treatment of intervertebral disc herniation. A preliminary report of a double-blind study. Spine 7:608–612PubMedCrossRef Fraser RD (1982) Chymopapain for the treatment of intervertebral disc herniation. A preliminary report of a double-blind study. Spine 7:608–612PubMedCrossRef
31.
Zurück zum Zitat Freeman BJC, Fraser RD, Cain CMJ, Hall DJ (2003) A randomised double-blind controlled efficacy study: intradiscal electrothermal therapy (IDET) versus placebo. J Bone Joint Surg 85B(Supp III):280 Freeman BJC, Fraser RD, Cain CMJ, Hall DJ (2003) A randomised double-blind controlled efficacy study: intradiscal electrothermal therapy (IDET) versus placebo. J Bone Joint Surg 85B(Supp III):280
32.
Zurück zum Zitat Fritzell P, Hagg O, Wessberg P, Nordwall A (2001) Lumbar fusion versus nonsurgical treatment for chronic low back pain: a multicenter randomized controlled trial from the Swedish Lumbar Spine Study Group. Spine 26:2521–2532PubMedCrossRef Fritzell P, Hagg O, Wessberg P, Nordwall A (2001) Lumbar fusion versus nonsurgical treatment for chronic low back pain: a multicenter randomized controlled trial from the Swedish Lumbar Spine Study Group. Spine 26:2521–2532PubMedCrossRef
33.
Zurück zum Zitat Frost FA, Jessen B, Siggaard-Andersen J (1980) A control, double-blind comparison of mepivacaine injection versus saline injection for myofascial pain. Lancet 1(8167):499–500PubMedCrossRef Frost FA, Jessen B, Siggaard-Andersen J (1980) A control, double-blind comparison of mepivacaine injection versus saline injection for myofascial pain. Lancet 1(8167):499–500PubMedCrossRef
34.
Zurück zum Zitat Gallagher J, Petriccione di Vadi PL, Wedley JR (1994) Radiofrequency facet joint denervation in the treatment of low back pain: a prospective controlled double-blind study to assess its efficacy. Pain Clin 7:193–198 Gallagher J, Petriccione di Vadi PL, Wedley JR (1994) Radiofrequency facet joint denervation in the treatment of low back pain: a prospective controlled double-blind study to assess its efficacy. Pain Clin 7:193–198
35.
Zurück zum Zitat Garvey TA, Marks MR, Wiesel SW (1989) A prospective, randomized, double-blind evaluation of trigger-point injection therapy for low-back pain. Spine 14:962–964PubMedCrossRef Garvey TA, Marks MR, Wiesel SW (1989) A prospective, randomized, double-blind evaluation of trigger-point injection therapy for low-back pain. Spine 14:962–964PubMedCrossRef
36.
Zurück zum Zitat Gibson JN, Grant IC, Waddell G (2000) Surgery for lumbar disc prolapse. Cochrane Database Syst Rev, Issue 3 Gibson JN, Grant IC, Waddell G (2000) Surgery for lumbar disc prolapse. Cochrane Database Syst Rev, Issue 3
37.
Zurück zum Zitat Gibson JNA, Waddell G (2005) Surgery for degenerative lumbar spondylosis. Cochrane Database Syst Rev, Issue 2 Gibson JNA, Waddell G (2005) Surgery for degenerative lumbar spondylosis. Cochrane Database Syst Rev, Issue 2
38.
Zurück zum Zitat Glynn Ch, Dawson D, Sanders R (1988) A double-blind comparison between epidural morphine and epidural clonidine in patients with chronic non-cancer pain. Pain 34:123–128CrossRef Glynn Ch, Dawson D, Sanders R (1988) A double-blind comparison between epidural morphine and epidural clonidine in patients with chronic non-cancer pain. Pain 34:123–128CrossRef
39.
Zurück zum Zitat Goodwin CB, Brighton CT, Guyer RD, Johnson JR, Light KI, Yuan HA (1999) A double-blind study of capacitively coupled electrical stimulation as an adjunct to lumbar spinal fusions. Spine 24:1349–1357PubMedCrossRef Goodwin CB, Brighton CT, Guyer RD, Johnson JR, Light KI, Yuan HA (1999) A double-blind study of capacitively coupled electrical stimulation as an adjunct to lumbar spinal fusions. Spine 24:1349–1357PubMedCrossRef
40.
Zurück zum Zitat Grob D, Humke T, Dvorak J (1995) Degenerative lumbar spinal stenosis. Decompression with and without arthrodesis. J Bone Joint Surg 77A:1036–1041 Grob D, Humke T, Dvorak J (1995) Degenerative lumbar spinal stenosis. Decompression with and without arthrodesis. J Bone Joint Surg 77A:1036–1041
41.
Zurück zum Zitat Hameroff SR, Crago BR, Blitt CD, Womble J, Kanel J (1981) Comparison of bupivacaine, etidocaine, and saline for trigger-point therapy. Anaesth Analg 60:752–755CrossRef Hameroff SR, Crago BR, Blitt CD, Womble J, Kanel J (1981) Comparison of bupivacaine, etidocaine, and saline for trigger-point therapy. Anaesth Analg 60:752–755CrossRef
42.
Zurück zum Zitat Heavner JE, Racz GB, Raj P (1999) Percutaneous epidural neuroplasty: prospective evaluation of 0.9% NaCl versus 10% NaCl with or without hyaluronidase. Reg Anesth Pain Med 24:202–207PubMedCrossRef Heavner JE, Racz GB, Raj P (1999) Percutaneous epidural neuroplasty: prospective evaluation of 0.9% NaCl versus 10% NaCl with or without hyaluronidase. Reg Anesth Pain Med 24:202–207PubMedCrossRef
43.
Zurück zum Zitat Hedtmann A, Fett H, Steffen R, Kramer J (1992) Chemonucleolysis using chymopapain and collagenase. 3-Year results of a prospective randomized study [Chemonukleolyse mit Chymopapain und Kollagenase. 3-Jahres-Ergebnisse einer prospektiv-randomisierten Studie]. Z Orthop Ihre Grenzgeb 130:36–44PubMed Hedtmann A, Fett H, Steffen R, Kramer J (1992) Chemonucleolysis using chymopapain and collagenase. 3-Year results of a prospective randomized study [Chemonukleolyse mit Chymopapain und Kollagenase. 3-Jahres-Ergebnisse einer prospektiv-randomisierten Studie]. Z Orthop Ihre Grenzgeb 130:36–44PubMed
44.
Zurück zum Zitat Henrikson L, Schmidt V, Eskesen V, Jantzen E (1996) A controlled study of microsurgical versus standard lumbar discectomy. Br J Neurosurg 10:289–293CrossRef Henrikson L, Schmidt V, Eskesen V, Jantzen E (1996) A controlled study of microsurgical versus standard lumbar discectomy. Br J Neurosurg 10:289–293CrossRef
45.
Zurück zum Zitat Herkowitz HN, Kurz LT (1991) Degenerative lumbar spondylolisthesis with spinal stenosis. A prospective study comparing decompression with decompression and intertransverse process arthrodesis. J Bone Joint Surg Am 73A:802–808 Herkowitz HN, Kurz LT (1991) Degenerative lumbar spondylolisthesis with spinal stenosis. A prospective study comparing decompression with decompression and intertransverse process arthrodesis. J Bone Joint Surg Am 73A:802–808
46.
Zurück zum Zitat Javid MJ, Nordby EJ, Ford LT, Hejna WJ, Whisler WW, Burton C (1983) Safety and efficacy of chymopapain (chymodiactin) in herniated nucleus pulposus with sciatica. JAMA 249:2489–2494PubMedCrossRef Javid MJ, Nordby EJ, Ford LT, Hejna WJ, Whisler WW, Burton C (1983) Safety and efficacy of chymopapain (chymodiactin) in herniated nucleus pulposus with sciatica. JAMA 249:2489–2494PubMedCrossRef
47.
Zurück zum Zitat Jenis LG, An HS, Stein R, Young B (2000) Prospective comparison of the effect of direct current electrical stimulation and pulsed electromagnetic fields on instrumented posterolateral lumbar arthrodesis. J Spinal Disord 13:290–296PubMedCrossRef Jenis LG, An HS, Stein R, Young B (2000) Prospective comparison of the effect of direct current electrical stimulation and pulsed electromagnetic fields on instrumented posterolateral lumbar arthrodesis. J Spinal Disord 13:290–296PubMedCrossRef
48.
Zurück zum Zitat Karppinen J, Malmivaara A, Kurunlahti M, Kyllonen E, Pienimaki T, Nieminen P, Ohinmaa A, Tervonen O, Vanharanta H (2001) Periradicular infiltration for sciatica: a randomized controlled trial. Spine 26:1059–1067PubMedCrossRef Karppinen J, Malmivaara A, Kurunlahti M, Kyllonen E, Pienimaki T, Nieminen P, Ohinmaa A, Tervonen O, Vanharanta H (2001) Periradicular infiltration for sciatica: a randomized controlled trial. Spine 26:1059–1067PubMedCrossRef
49.
Zurück zum Zitat Keller A, Brox JI, Gunderson R, Holm I, Friis A, Reikeras O (2004) Trunk muscle strength, cross-sectional area and density in patients with chronic low back pain randomized to lumbar fusion or cognitive intervention and exercises. Spine 29:3–8PubMedCrossRef Keller A, Brox JI, Gunderson R, Holm I, Friis A, Reikeras O (2004) Trunk muscle strength, cross-sectional area and density in patients with chronic low back pain randomized to lumbar fusion or cognitive intervention and exercises. Spine 29:3–8PubMedCrossRef
50.
Zurück zum Zitat Khot A, Bowditch M, Powell J, Sharp D (2004) The use of intradiscal steroid therapy for lumbar spinal discogenic pain: a randomized controlled trial. Spine 29:833–836PubMedCrossRef Khot A, Bowditch M, Powell J, Sharp D (2004) The use of intradiscal steroid therapy for lumbar spinal discogenic pain: a randomized controlled trial. Spine 29:833–836PubMedCrossRef
51.
Zurück zum Zitat Kitchel SH, Matteri RE (2002) Prospective randomized evaluation of PLIF in degenerative spondylolisthesis patients over 60 years old. Curr Concepts Rev Kitchel SH, Matteri RE (2002) Prospective randomized evaluation of PLIF in degenerative spondylolisthesis patients over 60 years old. Curr Concepts Rev
52.
Zurück zum Zitat Klein RG, Eek BC, DeLong WB, Mooney V (1993) A randomized double-blind trial of dextrose-glycerine-phenol injections for chronic, low back pain. J Spinal Disord 6:23–33PubMedCrossRef Klein RG, Eek BC, DeLong WB, Mooney V (1993) A randomized double-blind trial of dextrose-glycerine-phenol injections for chronic, low back pain. J Spinal Disord 6:23–33PubMedCrossRef
53.
Zurück zum Zitat Kotilainen E, Muittari P, Kirvela O (1997) Intradiscal glycerol or bupivacaine in the treatment of low back pain. Acta Neurochir (Wien) 139:541–545CrossRef Kotilainen E, Muittari P, Kirvela O (1997) Intradiscal glycerol or bupivacaine in the treatment of low back pain. Acta Neurochir (Wien) 139:541–545CrossRef
54.
Zurück zum Zitat Kraemer J, Ludwig J, Bickert U, Owczarek V, Traupe M (1997) Lumbar epidural perineural injection: a new technique. Eur Spine J 6:357–361PubMedCrossRef Kraemer J, Ludwig J, Bickert U, Owczarek V, Traupe M (1997) Lumbar epidural perineural injection: a new technique. Eur Spine J 6:357–361PubMedCrossRef
55.
Zurück zum Zitat Lagarrigue J, Chaynes P (1994) Comparative study of disk surgery with or without microscopy. A prospective study of 80 cases [Etude comparative de la chirurgie discale avec et sans microscope]. Neurochirurgie 40:116–120PubMed Lagarrigue J, Chaynes P (1994) Comparative study of disk surgery with or without microscopy. A prospective study of 80 cases [Etude comparative de la chirurgie discale avec et sans microscope]. Neurochirurgie 40:116–120PubMed
56.
Zurück zum Zitat Lavignolle B, Vital JM, Baulny D, Grenier F, Castagnera L (1987) Comparative study of surgery and chemonucleolysis in the treatment of sciatica caused by a herniated disk [Etudes comparees de la chirurgie et de la chimionucleolyse dans le traitement de la sciatique par hernie discale]. Acta Orthop Belg 53:244–249PubMed Lavignolle B, Vital JM, Baulny D, Grenier F, Castagnera L (1987) Comparative study of surgery and chemonucleolysis in the treatment of sciatica caused by a herniated disk [Etudes comparees de la chirurgie et de la chimionucleolyse dans le traitement de la sciatique par hernie discale]. Acta Orthop Belg 53:244–249PubMed
57.
Zurück zum Zitat Leclaire R, Fortin L, Lambert R (2001) Radiofrequency facet joint denervation in the treatment of low back pain: a placebo-controlled clinical trial to assess efficacy. Spine 26:1411–1416PubMedCrossRef Leclaire R, Fortin L, Lambert R (2001) Radiofrequency facet joint denervation in the treatment of low back pain: a placebo-controlled clinical trial to assess efficacy. Spine 26:1411–1416PubMedCrossRef
58.
Zurück zum Zitat Lilius G, Lassonen AM, Myllynen P, Harilainen A, Salo L (1989) The lumbar facet joint syndrome––significance of inappropriate signs. A randomized, placebo controlled trial. French J Orthop Surg 3:479–486 Lilius G, Lassonen AM, Myllynen P, Harilainen A, Salo L (1989) The lumbar facet joint syndrome––significance of inappropriate signs. A randomized, placebo controlled trial. French J Orthop Surg 3:479–486
59.
Zurück zum Zitat Lilius G, Harilainen A, Laasonen EM, Myllynen P (1990) Chronic unilateral low back pain. Predictors of outcome of facet joint injections. Spine 15:780–782PubMedCrossRef Lilius G, Harilainen A, Laasonen EM, Myllynen P (1990) Chronic unilateral low back pain. Predictors of outcome of facet joint injections. Spine 15:780–782PubMedCrossRef
60.
Zurück zum Zitat Lord SM, Barnsley L, Wallis BJ (1996) Percutaneous radio-frequency neurotomy for chronic cervical zygapophyseal-joint pain. N Engl J Med 335:1721–1726PubMedCrossRef Lord SM, Barnsley L, Wallis BJ (1996) Percutaneous radio-frequency neurotomy for chronic cervical zygapophyseal-joint pain. N Engl J Med 335:1721–1726PubMedCrossRef
61.
Zurück zum Zitat Lutze M, Stendel R, Vesper J, Brock M (1997) Periradicular therapy in lumbar radicular syndromes: methodology and results. Acta Neurochir (Wien) 139:719–724CrossRef Lutze M, Stendel R, Vesper J, Brock M (1997) Periradicular therapy in lumbar radicular syndromes: methodology and results. Acta Neurochir (Wien) 139:719–724CrossRef
62.
Zurück zum Zitat Marks RC, Houston T, Thulbourne T (1992) Facet joint injection and facet nerve block: a randomised comparison in 86 patients with chronic low back pain. Pain 49:325–328PubMedCrossRef Marks RC, Houston T, Thulbourne T (1992) Facet joint injection and facet nerve block: a randomised comparison in 86 patients with chronic low back pain. Pain 49:325–328PubMedCrossRef
63.
Zurück zum Zitat Mathews JA, Mills SB, Jenkins VM, Grimes SM, Morkel MJ, Mathews W, Scott CM, Sittampalam Y (1987) Back pain and sciatica: controlled trials of manipulation, traction, sclerosant and epidural injections. Br J Rheum 26:416–423CrossRef Mathews JA, Mills SB, Jenkins VM, Grimes SM, Morkel MJ, Mathews W, Scott CM, Sittampalam Y (1987) Back pain and sciatica: controlled trials of manipulation, traction, sclerosant and epidural injections. Br J Rheum 26:416–423CrossRef
64.
Zurück zum Zitat Mayer HM, Brock M (1993) Percutaneous endoscopic discectomy: surgical technique and preliminary results compared to microsurgical discectomy. J Neurosurg 78:216–225PubMedCrossRef Mayer HM, Brock M (1993) Percutaneous endoscopic discectomy: surgical technique and preliminary results compared to microsurgical discectomy. J Neurosurg 78:216–225PubMedCrossRef
65.
Zurück zum Zitat McGuire RA, Amundson GM (1993) The use of primary internal fixation in spondylolisthesis. Spine 18:1662–1672PubMedCrossRef McGuire RA, Amundson GM (1993) The use of primary internal fixation in spondylolisthesis. Spine 18:1662–1672PubMedCrossRef
66.
Zurück zum Zitat Moller H, Hedlund R (2000) Surgery versus conservative management in adult isthmic spondylolisthesis––a prospective randomized study: part 1. Spine 25:1711–1715PubMedCrossRef Moller H, Hedlund R (2000) Surgery versus conservative management in adult isthmic spondylolisthesis––a prospective randomized study: part 1. Spine 25:1711–1715PubMedCrossRef
67.
Zurück zum Zitat Moller H, Hedlund R (2000) Instrumented and noninstrumented posterolateral fusion in adult spondylolisthesis––a prospective randomized study: part 2. Spine 25:1716–1721PubMedCrossRef Moller H, Hedlund R (2000) Instrumented and noninstrumented posterolateral fusion in adult spondylolisthesis––a prospective randomized study: part 2. Spine 25:1716–1721PubMedCrossRef
68.
Zurück zum Zitat Mooney V (1990) A randomized double-blind prospective study of the efficacy of pulsed electromagnetic fields for interbody lumbar fusions. Spine 15:708–712PubMedCrossRef Mooney V (1990) A randomized double-blind prospective study of the efficacy of pulsed electromagnetic fields for interbody lumbar fusions. Spine 15:708–712PubMedCrossRef
69.
Zurück zum Zitat Muralikuttan KP, Hamilton A, Kernohan WG, Mollan RA, Adair IV (1992) A prospective randomized trial of chemonucleolysis and conventional disc surgery in single level lumbar disc herniation. Spine 17:381–387PubMedCrossRef Muralikuttan KP, Hamilton A, Kernohan WG, Mollan RA, Adair IV (1992) A prospective randomized trial of chemonucleolysis and conventional disc surgery in single level lumbar disc herniation. Spine 17:381–387PubMedCrossRef
70.
Zurück zum Zitat Nelemans PJ, de Bie RA, de Vet HC, Sturmans F (2000) Injection therapy for subacute and chronic benign low back pain. Cochrane Database Syst Rev, Issue 2 Nelemans PJ, de Bie RA, de Vet HC, Sturmans F (2000) Injection therapy for subacute and chronic benign low back pain. Cochrane Database Syst Rev, Issue 2
71.
Zurück zum Zitat Niemisto L, Kalso E, Malmivaara A, Seitsalo S, Hurri H (2003) Radiofrequency denervation for neck and back pain: a systematic review within the framework of the Cochrane collaboration back review group. Spine 28:1877–1888PubMedCrossRef Niemisto L, Kalso E, Malmivaara A, Seitsalo S, Hurri H (2003) Radiofrequency denervation for neck and back pain: a systematic review within the framework of the Cochrane collaboration back review group. Spine 28:1877–1888PubMedCrossRef
72.
Zurück zum Zitat Ongley MJ, Klein RG, Dorman TA, Eek BC, Hubert LJ (1987) A new approach to the treatment of chronic low back pain. Lancet 2(8551):143–146PubMedCrossRef Ongley MJ, Klein RG, Dorman TA, Eek BC, Hubert LJ (1987) A new approach to the treatment of chronic low back pain. Lancet 2(8551):143–146PubMedCrossRef
73.
Zurück zum Zitat Pauza KJ, Howell S, Dreyfuss P, Peloza JH, Dawson K, Bogduk N (2004) A randomized, placebo-controlled trial of intradiscal electrotermal therapy for the treatment of discogenic low back pain. Spine J 4:27–35PubMedCrossRef Pauza KJ, Howell S, Dreyfuss P, Peloza JH, Dawson K, Bogduk N (2004) A randomized, placebo-controlled trial of intradiscal electrotermal therapy for the treatment of discogenic low back pain. Spine J 4:27–35PubMedCrossRef
74.
Zurück zum Zitat Postacchini F, Cinotti G, Perugia D, Gumina S (1993) The surgical treatment of central lumbar stenosis. J Bone Joint Surg 75B:386–392 Postacchini F, Cinotti G, Perugia D, Gumina S (1993) The surgical treatment of central lumbar stenosis. J Bone Joint Surg 75B:386–392
75.
Zurück zum Zitat Revel M, Payan C, Vallee C, Laredo JD, Lassale B, Roux C (1993) Automated percutaneous lumbar discectomy versus chemonucleolysis in the treatment of sciatica. A randomized multicenter trial. Spine 18:1–7PubMedCrossRef Revel M, Payan C, Vallee C, Laredo JD, Lassale B, Roux C (1993) Automated percutaneous lumbar discectomy versus chemonucleolysis in the treatment of sciatica. A randomized multicenter trial. Spine 18:1–7PubMedCrossRef
76.
Zurück zum Zitat Riew KD, Yin Y, Gilula L, Bridwell KH, Lenke LG, Lauryssen C, Goette K (2000) The effect of nerve-root injections on the need for operative treatment of lumbar radicular pain. A prospective, randomized, controlled, double-blind study. J Bone Joint Surg 82A:1589–1593 Riew KD, Yin Y, Gilula L, Bridwell KH, Lenke LG, Lauryssen C, Goette K (2000) The effect of nerve-root injections on the need for operative treatment of lumbar radicular pain. A prospective, randomized, controlled, double-blind study. J Bone Joint Surg 82A:1589–1593
77.
Zurück zum Zitat Rocco AG, Frank E, Kaul AF, Lipson SJ, Gallo JP (1989) Epidural steroids, epidural morphine and epidural steroids combined with morphine in the treatment of post-laminectomy syndrome. Pain 36:297–303PubMedCrossRef Rocco AG, Frank E, Kaul AF, Lipson SJ, Gallo JP (1989) Epidural steroids, epidural morphine and epidural steroids combined with morphine in the treatment of post-laminectomy syndrome. Pain 36:297–303PubMedCrossRef
78.
Zurück zum Zitat Rogers P, Nash T, Schiller D, Norman J (1992) Epidural steroids for sciatica. Pain Clin 5:67–72 Rogers P, Nash T, Schiller D, Norman J (1992) Epidural steroids for sciatica. Pain Clin 5:67–72
79.
Zurück zum Zitat Samwel H, Slappendel R, Crul BJ (2000) Psychological predictors of the effectiveness of radiofrequency lesioning of the cervical spinal dorsal ganglion (RF-DRG). Eur J Pain 4:149–155PubMedCrossRef Samwel H, Slappendel R, Crul BJ (2000) Psychological predictors of the effectiveness of radiofrequency lesioning of the cervical spinal dorsal ganglion (RF-DRG). Eur J Pain 4:149–155PubMedCrossRef
80.
Zurück zum Zitat Sasso RC, Kitchel SH, Dawson EG (2004) A prospective, randomized controlled clinical trial of anterior lumbar interbody fusion using a titanium cylindrical threaded fusion device. Spine 29:113–122PubMedCrossRef Sasso RC, Kitchel SH, Dawson EG (2004) A prospective, randomized controlled clinical trial of anterior lumbar interbody fusion using a titanium cylindrical threaded fusion device. Spine 29:113–122PubMedCrossRef
81.
Zurück zum Zitat Schofferman J, Slosar P, Reynolds J, Goldthwaite N, Koestler M (2001) A prospective randomized comparison of 270° fusions to 360° fusions (circumferential fusions). Spine 26:E207–E212PubMedCrossRef Schofferman J, Slosar P, Reynolds J, Goldthwaite N, Koestler M (2001) A prospective randomized comparison of 270° fusions to 360° fusions (circumferential fusions). Spine 26:E207–E212PubMedCrossRef
82.
Zurück zum Zitat Schwetschenau R, Ramirez A, Johnston J, Barnes E, Wiggs C, Martins AN (1976) Double-blind evaluation of intradiscal chymopapain for herniated lumbar discs. Early results. J Neurosurg 45:622–627 Schwetschenau R, Ramirez A, Johnston J, Barnes E, Wiggs C, Martins AN (1976) Double-blind evaluation of intradiscal chymopapain for herniated lumbar discs. Early results. J Neurosurg 45:622–627
83.
Zurück zum Zitat Serrao JM, Marks RL, Morley SJ, Goodchild CS (1992) Intrathecal midazolam for the treatment of chronic mechanical low back pain: a controlled comparison with epidural steroid in a pilot study. Pain 48:5–12PubMedCrossRef Serrao JM, Marks RL, Morley SJ, Goodchild CS (1992) Intrathecal midazolam for the treatment of chronic mechanical low back pain: a controlled comparison with epidural steroid in a pilot study. Pain 48:5–12PubMedCrossRef
84.
Zurück zum Zitat Shealy CN (1975) Percutaneous radiofrequency denervation of spinal facets. Treatment for chronic back pain and sciatica. J Neurosurg 43:448–451PubMed Shealy CN (1975) Percutaneous radiofrequency denervation of spinal facets. Treatment for chronic back pain and sciatica. J Neurosurg 43:448–451PubMed
85.
Zurück zum Zitat Simmons JW, McMillin JN, Emery SF, Kimmich SJ (1992) Intradiscal steroids: a prospective double-blind clinical trial. Spine 17:172–175CrossRef Simmons JW, McMillin JN, Emery SF, Kimmich SJ (1992) Intradiscal steroids: a prospective double-blind clinical trial. Spine 17:172–175CrossRef
86.
Zurück zum Zitat Slappendel R, Crul BJ, Braak GJ (1997) The efficacy of radiofrequency lesioning of the cervical spinal dorsal root ganglion in a double blinded randomized study: no difference between 40 degrees C and 67 degrees C treatments. Pain 73:159–163PubMedCrossRef Slappendel R, Crul BJ, Braak GJ (1997) The efficacy of radiofrequency lesioning of the cervical spinal dorsal root ganglion in a double blinded randomized study: no difference between 40 degrees C and 67 degrees C treatments. Pain 73:159–163PubMedCrossRef
87.
Zurück zum Zitat Sonne M, Christensen K, Hansen SE, Jensen EM (1985) Injection of steroids and local anaesthetics as therapy for low-back pain. Scand J Rheum 14:343–345PubMedCrossRef Sonne M, Christensen K, Hansen SE, Jensen EM (1985) Injection of steroids and local anaesthetics as therapy for low-back pain. Scand J Rheum 14:343–345PubMedCrossRef
88.
Zurück zum Zitat Thomsen K, Christensen FB, Eiskjaer SP, Hansen ES, Fruensgaard S, Bunger CE (1997) The effect of pedicle screw instrumentation on functional outcome and fusion rates in posterolateral lumbar spinal fusion. A prospective randomized clinical study. Spine 22:2813–2822PubMedCrossRef Thomsen K, Christensen FB, Eiskjaer SP, Hansen ES, Fruensgaard S, Bunger CE (1997) The effect of pedicle screw instrumentation on functional outcome and fusion rates in posterolateral lumbar spinal fusion. A prospective randomized clinical study. Spine 22:2813–2822PubMedCrossRef
89.
Zurück zum Zitat Tullberg T, Isacson J, Weidenhielm L (1993) Does microscopic removal of lumbar disc herniation lead to better results than the standard procedure? Results of a one-year randomized study. Spine 18:24–27PubMedCrossRef Tullberg T, Isacson J, Weidenhielm L (1993) Does microscopic removal of lumbar disc herniation lead to better results than the standard procedure? Results of a one-year randomized study. Spine 18:24–27PubMedCrossRef
90.
Zurück zum Zitat Vad VB, Bhat AL, Lutz GE, Cammisa F (2002) Transforaminal epidural steroid injections in lumbosacral radiculopathy: a prospective randomized study. Spine 27:11–16PubMedCrossRef Vad VB, Bhat AL, Lutz GE, Cammisa F (2002) Transforaminal epidural steroid injections in lumbosacral radiculopathy: a prospective randomized study. Spine 27:11–16PubMedCrossRef
91.
Zurück zum Zitat Van Alphen HA, Braakman R, Bezemer PD, Broere G, Berfelo MW (1989) Chemonucleolysis versus discectomy: a randomized multicenter trial. J Neurosurg 70:869–875PubMed Van Alphen HA, Braakman R, Bezemer PD, Broere G, Berfelo MW (1989) Chemonucleolysis versus discectomy: a randomized multicenter trial. J Neurosurg 70:869–875PubMed
92.
Zurück zum Zitat Van Kleef M, Liem L, Lousberg R (1996) Radiofrequency lesion adjacent to the dorsal root ganglion for cervicobrachial pain: a prospective double blind randomized study. Neurosurgery 38:1127–1131PubMedCrossRef Van Kleef M, Liem L, Lousberg R (1996) Radiofrequency lesion adjacent to the dorsal root ganglion for cervicobrachial pain: a prospective double blind randomized study. Neurosurgery 38:1127–1131PubMedCrossRef
93.
Zurück zum Zitat Van Kleef M, Barendse GA, Kessels A (1999) Randomized trial of radiofrequency lumbar facet denervation for chronic low back pain. Spine 24:1937–1942PubMedCrossRef Van Kleef M, Barendse GA, Kessels A (1999) Randomized trial of radiofrequency lumbar facet denervation for chronic low back pain. Spine 24:1937–1942PubMedCrossRef
94.
Zurück zum Zitat Wallis BJ, Lord SM, Bogduk N (1997) Resolution of psychological distress of whiplash patients following treatment by radiofrequency neurotomy: a randomised, double-blind, placebo-controlled trial. Pain 73:15–22PubMedCrossRef Wallis BJ, Lord SM, Bogduk N (1997) Resolution of psychological distress of whiplash patients following treatment by radiofrequency neurotomy: a randomised, double-blind, placebo-controlled trial. Pain 73:15–22PubMedCrossRef
95.
Zurück zum Zitat Weber H (1978) Lumbar disc herniation. A prospective study of prognostic factors including a controlled trial (see also pp89–120). J Oslo City Hosp 28:33–64PubMed Weber H (1978) Lumbar disc herniation. A prospective study of prognostic factors including a controlled trial (see also pp89–120). J Oslo City Hosp 28:33–64PubMed
96.
Zurück zum Zitat Weber H (1983) Lumbar disc herniation. A controlled, prospective study with ten years of observation. Spine 8:131–140PubMedCrossRef Weber H (1983) Lumbar disc herniation. A controlled, prospective study with ten years of observation. Spine 8:131–140PubMedCrossRef
97.
Zurück zum Zitat Yelland MJ, Glasziou PP, Bogduk N, Schluter PJ, McKernon M (2004) Prolotherapy injections, saline injections, and exercises for chronic low-back pain: a randomized trial. Spine 29:9–16PubMedCrossRef Yelland MJ, Glasziou PP, Bogduk N, Schluter PJ, McKernon M (2004) Prolotherapy injections, saline injections, and exercises for chronic low-back pain: a randomized trial. Spine 29:9–16PubMedCrossRef
98.
Zurück zum Zitat Yelland MJ, Del Mar C, Pirozzo S, Schoene ML (2004) Prolotherapy injections for chronic low back pain: a systematic review. Spine 29:2126–2133PubMedCrossRef Yelland MJ, Del Mar C, Pirozzo S, Schoene ML (2004) Prolotherapy injections for chronic low back pain: a systematic review. Spine 29:2126–2133PubMedCrossRef
99.
Zurück zum Zitat Zdeblick TA (1993) A prospective, randomized study of lumbar fusion. Preliminary results. Spine 18:983–991PubMedCrossRef Zdeblick TA (1993) A prospective, randomized study of lumbar fusion. Preliminary results. Spine 18:983–991PubMedCrossRef
Metadaten
Titel
Outcome of invasive treatment modalities on back pain and sciatica: an evidence-based review
verfasst von
Maurits W. van Tulder
Bart Koes
Seppo Seitsalo
Antti Malmivaara
Publikationsdatum
01.01.2006
Erschienen in
European Spine Journal / Ausgabe Sonderheft 1/2006
Print ISSN: 0940-6719
Elektronische ISSN: 1432-0932
DOI
https://doi.org/10.1007/s00586-005-1049-5

Weitere Artikel der Sonderheft 1/2006

European Spine Journal 1/2006 Zur Ausgabe

Arthropedia

Grundlagenwissen der Arthroskopie und Gelenkchirurgie. Erweitert durch Fallbeispiele, Videos und Abbildungen. 
» Jetzt entdecken

Update Orthopädie und Unfallchirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.