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Erschienen in: Pediatric Surgery International 7/2017

22.04.2017 | Original Article

Outcome of stoma closure in babies with necrotising enterocolitis: early vs late closure

verfasst von: Debasish Bijoykrishna Banerjee, Hasanthi Vithana, Shilpa Sharma, Thomas Tat Ming Tsang

Erschienen in: Pediatric Surgery International | Ausgabe 7/2017

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Abstract

Newborns undergoing surgery for necrotizing enterocolitis (NEC) often require a stoma. Currently, there is no consensus regarding the best time for stoma closure (SC). Our aim was to determine the outcomes of early versus late closure.

Methods

Retrospective analysis of patients who underwent SC following stoma formation for NEC between Jan 2009 and July 2015 was done. Early (EC) versus late closure (LC) was defined as less than 10 weeks versus at or after 10 weeks of stoma formation.

Results

Of 36 patients, M:F was 23:13. Indications for laparotomy were pneumoperitoneum (30) and gangrene (6). Postoperatively, 9/15 (60.0%) of EC group required ventilator support versus none in LC group (p < 0.05). It took longer to establish full feeds following EC (12 days) versus LC (8 days). Median duration of postoperative hospital stay following EC was 31 days (18–35) versus 7 days (4–54) following LC. Three patients were re-operated for intestinal obstruction (two following EC, one following LC). Three patients developed incisional hernia after EC versus none after LC (p < 0.05). One patient died after EC due to staphylococcus septicaemia.

Conclusion

Early closure before 10 weeks of formation for NEC patients is associated with significant morbidity, increased ventilator requirements and chances of developing incisional hernia.
Literatur
1.
Zurück zum Zitat Rothstein FC, Halpin TC Jr, Kliegman RJ, Izant RJ Jr (1982) Importance of early ileostomy closure to prevent chronic salt and water losses after necrotizing enterocolitis. Pediatrics 70:249–253PubMed Rothstein FC, Halpin TC Jr, Kliegman RJ, Izant RJ Jr (1982) Importance of early ileostomy closure to prevent chronic salt and water losses after necrotizing enterocolitis. Pediatrics 70:249–253PubMed
2.
Zurück zum Zitat Al-Hudhaif J, Phillips S, Gholum S, Puligandla PP, Flageole H (2009) The timing of enterostomy reversal after necrotizing enterocolitis. J Pediatr Surg 44(5):924–927CrossRefPubMed Al-Hudhaif J, Phillips S, Gholum S, Puligandla PP, Flageole H (2009) The timing of enterostomy reversal after necrotizing enterocolitis. J Pediatr Surg 44(5):924–927CrossRefPubMed
3.
Zurück zum Zitat Gertler JP, Seashore JH, Touloukian RJ (1987) Early ileostomy closure in necrotizing enterocolitis. J Pediatr Surg 22(2):140–143CrossRefPubMed Gertler JP, Seashore JH, Touloukian RJ (1987) Early ileostomy closure in necrotizing enterocolitis. J Pediatr Surg 22(2):140–143CrossRefPubMed
4.
Zurück zum Zitat Struijs MC, Sloots CE, Hop WC, Tibboel D, Wijnen RM (2012) The timing of ostomy closure in infants with necrotizing enterocolitis: a systematic review. Pediatr Surg Int 28(7):667–672CrossRefPubMedPubMedCentral Struijs MC, Sloots CE, Hop WC, Tibboel D, Wijnen RM (2012) The timing of ostomy closure in infants with necrotizing enterocolitis: a systematic review. Pediatr Surg Int 28(7):667–672CrossRefPubMedPubMedCentral
5.
Zurück zum Zitat Musemeche CA, Kosloske AM, Ricketts RR (1987) Enterostomy in necrotizing enterocolitis: an analysis of techniques and timing of closure. J Pediatr Surg 22(6):479–483CrossRefPubMed Musemeche CA, Kosloske AM, Ricketts RR (1987) Enterostomy in necrotizing enterocolitis: an analysis of techniques and timing of closure. J Pediatr Surg 22(6):479–483CrossRefPubMed
6.
Zurück zum Zitat Veenstra M, Nagappala K, Danielson L, Klien M (2015) Timing of ostomy reversal in neonates with necrotizing enterocolitis. Eur J Pediatr Surg 25(3):231–235PubMed Veenstra M, Nagappala K, Danielson L, Klien M (2015) Timing of ostomy reversal in neonates with necrotizing enterocolitis. Eur J Pediatr Surg 25(3):231–235PubMed
7.
Zurück zum Zitat Attard MI, Patel N, Simpson J (2012) Change from intralipid to SMOF lipid is associated with improved liver function in infants with PN associated liver disease. Arch Dis Child 97:54–55CrossRef Attard MI, Patel N, Simpson J (2012) Change from intralipid to SMOF lipid is associated with improved liver function in infants with PN associated liver disease. Arch Dis Child 97:54–55CrossRef
8.
Zurück zum Zitat Lee J, Kang MJ, Kim HS, Shin SH, Kim HY, Kim EK (2014) Enterostomy closure timing for minimising postoperative complications in premature infants. Pediatr Neonatol 55:363–368CrossRefPubMed Lee J, Kang MJ, Kim HS, Shin SH, Kim HY, Kim EK (2014) Enterostomy closure timing for minimising postoperative complications in premature infants. Pediatr Neonatol 55:363–368CrossRefPubMed
9.
Zurück zum Zitat Weber TR, Tracy TF Jr, Silen ML, Powell MA (1995) Enterostomy and its closure in newborns. Arch Surg 130:534–537CrossRefPubMed Weber TR, Tracy TF Jr, Silen ML, Powell MA (1995) Enterostomy and its closure in newborns. Arch Surg 130:534–537CrossRefPubMed
10.
Zurück zum Zitat Talbot LJ, Sinyard RD, Rialon KL, Englum BR, Tracy ET, Rice HE, Adibe OO (2017) Influence of weight at enterostomy reversal on surgical outcomes in infants after emergent neonatal stoma creation. J Pediatr Surg 52:35–39CrossRefPubMed Talbot LJ, Sinyard RD, Rialon KL, Englum BR, Tracy ET, Rice HE, Adibe OO (2017) Influence of weight at enterostomy reversal on surgical outcomes in infants after emergent neonatal stoma creation. J Pediatr Surg 52:35–39CrossRefPubMed
11.
Zurück zum Zitat Lawn JE, Blencowe H, Oza S, You D, Lee AC, Waiswa P, Merek L, Bhutta Z, Barros AJD, Mathers C, Cousens SN (2014) Every Newborn: progress, priorities, and potential beyond survival. Lancet 384:189–205CrossRefPubMed Lawn JE, Blencowe H, Oza S, You D, Lee AC, Waiswa P, Merek L, Bhutta Z, Barros AJD, Mathers C, Cousens SN (2014) Every Newborn: progress, priorities, and potential beyond survival. Lancet 384:189–205CrossRefPubMed
12.
Zurück zum Zitat Kliegman RM, Walsh MC (1987) Neonatal necrotizing enterocolitis: pathogenesis, classification and spectrum of disease. Curr Probl Pediatr 17(4):243–288 Kliegman RM, Walsh MC (1987) Neonatal necrotizing enterocolitis: pathogenesis, classification and spectrum of disease. Curr Probl Pediatr 17(4):243–288
Metadaten
Titel
Outcome of stoma closure in babies with necrotising enterocolitis: early vs late closure
verfasst von
Debasish Bijoykrishna Banerjee
Hasanthi Vithana
Shilpa Sharma
Thomas Tat Ming Tsang
Publikationsdatum
22.04.2017
Verlag
Springer Berlin Heidelberg
Erschienen in
Pediatric Surgery International / Ausgabe 7/2017
Print ISSN: 0179-0358
Elektronische ISSN: 1437-9813
DOI
https://doi.org/10.1007/s00383-017-4084-5

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