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Erschienen in:

09.07.2023 | Research

Outcomes and Risk Factors of Interventions for Pediatric Post-operative Pulmonary Vein Stenosis

verfasst von: Kristin T. Fujita, Michael P. DiLorenzo, Usha S. Krishnan, Mariel E. Turner, Oliver M. Barry, Alejandro J. Torres, Emile A. Bacha, David Kalfa, Matthew A. Crystal

Erschienen in: Pediatric Cardiology | Ausgabe 8/2023

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Abstract

Pulmonary vein stenosis (PVS) in children is a challenging condition with poor outcomes. Post-operative stenosis can occur after repair of anomalous pulmonary venous return (APVR) or stenosis within native veins. There is limited data on the outcomes of post-operative PVS. Our objective was to review our experience and assess surgical and transcatheter outcomes. Single-center retrospective study was performed including patients < 18 years who developed restenosis after baseline pulmonary vein surgery that required additional intervention(s) from 1/2005 to 1/2020. Non-invasive imaging, catheterization and surgical data were reviewed. We identified 46 patients with post-operative PVS with 11 (23.9%) patient deaths. Median age at index procedure was 7.2 months (range 1 month–10 years), and median follow-up was 10.8 months (range 1 day–13 years). Index procedure was surgical in 36 (78.3%) and transcatheter in 10 (21.7%). Twenty-three (50%) patients developed vein atresia. Mortality was not associated with number of affected veins, vein atresia, or procedure type. Single ventricle physiology, complex congenital heart disease (CCHD), and genetic disorders were associated with mortality. Survival rate was higher in APVR patients (p = 0.03). Patients with three or more interventions had a higher survival rate compared to patients with 1–2 interventions (p = 0.02). Male gender, necrotizing enterocolitis, and diffuse hypoplasia were associated with vein atresia. In post-operative PVS, mortality is associated with CCHD, single ventricle physiology, and genetic disorders. Vein atresia is associated with male gender, necrotizing enterocolitis, and diffuse hypoplasia. Multiple repeated interventions may offer a patient survival benefit; however, larger prospective studies are necessary to elucidate this relationship further.
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Metadaten
Titel
Outcomes and Risk Factors of Interventions for Pediatric Post-operative Pulmonary Vein Stenosis
verfasst von
Kristin T. Fujita
Michael P. DiLorenzo
Usha S. Krishnan
Mariel E. Turner
Oliver M. Barry
Alejandro J. Torres
Emile A. Bacha
David Kalfa
Matthew A. Crystal
Publikationsdatum
09.07.2023
Verlag
Springer US
Erschienen in
Pediatric Cardiology / Ausgabe 8/2023
Print ISSN: 0172-0643
Elektronische ISSN: 1432-1971
DOI
https://doi.org/10.1007/s00246-023-03214-w

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