Skip to main content
Erschienen in: Journal of Gastrointestinal Surgery 12/2015

01.12.2015 | Original Article

Outcomes Improvement Is Not Continuous Along the Learning Curve for Pancreaticoduodenectomy at the Hospital Level

verfasst von: Taylor M. Coe, Zhi Ven Fong, Samuel E. Wilson, Mark A. Talamini, Keith D. Lillemoe, David C. Chang

Erschienen in: Journal of Gastrointestinal Surgery | Ausgabe 12/2015

Einloggen, um Zugang zu erhalten

Abstract

Background

Most studies on learning curves for pancreaticoduodenectomy have been based on single-surgeon series at tertiary academic centers or are inferred indirectly from volume-outcome relationships. Our aim is to describe mortality rates associated with cumulative surgical experience among non-teaching hospitals.

Study Design

Observational study of a statewide inpatient database. Analysis included hospitals that began performing pancreaticoduodenectomy between 1996 and 2010, as captured by the California Office of Statewide Health Planning and Development database. Cases were numbered sequentially within each hospital. The same sequential series (e.g., first 10 cases, 11th through 20th cases) were identified across hospitals. The outcome measure was in-hospital mortality.

Results

A total of 1210 cases from 143 non-teaching hospitals were analyzed. The average age was 63 years old, and the majority of patients were non-Hispanic white. The median overall mortality rate was 9.75 %. The mortality rate for the first 10 aggregated cases was 11.3 %. This improved for subsequent cases, reaching 7.1 % for the 21st–30th cases. However, the mortality rate then increased, reaching 16.7 % by the 41st–50th cases before falling to 0.0 % by the 61st–70th cases.

Conclusions

Initial improvement in surgical outcomes relative to cumulative surgical experience is not sustained. It is likely that factors other than surgical experience affect outcomes, such as less rigorous assessment of comorbidities or changes in support services. Vigilance regarding outcomes should be maintained even after initial improvements.
Literatur
1.
Zurück zum Zitat Harrysson IJ, Cook J, Sirimanna P, et al. Systematic review of learning curves for minimally invasive abdominal surgery: a review of the methodology of data collection, depiction of outcomes, and statistical analysis. Ann Surg 2014; 260(1):37–45.CrossRefPubMed Harrysson IJ, Cook J, Sirimanna P, et al. Systematic review of learning curves for minimally invasive abdominal surgery: a review of the methodology of data collection, depiction of outcomes, and statistical analysis. Ann Surg 2014; 260(1):37–45.CrossRefPubMed
2.
Zurück zum Zitat Gladwell M. Outliers: the story of success. New York: Little, Brown and Co, 2008. Gladwell M. Outliers: the story of success. New York: Little, Brown and Co, 2008.
4.
Zurück zum Zitat Fisher WE, Hodges SE, Wu MF, et al. Assessment of the learning curve for pancreaticoduodenectomy. Am J Surg 2012; 203(6):684–90.CrossRefPubMed Fisher WE, Hodges SE, Wu MF, et al. Assessment of the learning curve for pancreaticoduodenectomy. Am J Surg 2012; 203(6):684–90.CrossRefPubMed
5.
Zurück zum Zitat Tseng JF, Pisters PW, Lee JE, et al. The learning curve in pancreatic surgery. Surgery 2007; 141(4):456–63.CrossRefPubMed Tseng JF, Pisters PW, Lee JE, et al. The learning curve in pancreatic surgery. Surgery 2007; 141(4):456–63.CrossRefPubMed
7.
Zurück zum Zitat Birkmeyer JD, Finlayson SR, Tosteson AN, et al. Effect of hospital volume on in-hospital mortality with pancreaticoduodenectomy. Surgery 1999; 125(3):250–6.CrossRefPubMed Birkmeyer JD, Finlayson SR, Tosteson AN, et al. Effect of hospital volume on in-hospital mortality with pancreaticoduodenectomy. Surgery 1999; 125(3):250–6.CrossRefPubMed
8.
Zurück zum Zitat Charlson ME, Pompei P, Ales KL, et al. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 1987; 40(5):373–83.CrossRefPubMed Charlson ME, Pompei P, Ales KL, et al. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 1987; 40(5):373–83.CrossRefPubMed
9.
Zurück zum Zitat Lieberman MD, Kilburn H, Lindsey M, et al. Relation of perioperative deaths to hospital volume among patients undergoing pancreatic resection for malignancy. Ann Surg 1995; 222(5):638–45.PubMedCentralCrossRefPubMed Lieberman MD, Kilburn H, Lindsey M, et al. Relation of perioperative deaths to hospital volume among patients undergoing pancreatic resection for malignancy. Ann Surg 1995; 222(5):638–45.PubMedCentralCrossRefPubMed
10.
Zurück zum Zitat Ho V, Heslin MJ. Effect of hospital volume and experience on in-hospital mortality for pancreaticoduodenectomy. Ann Surg 2003; 237(4):509–14.PubMedCentralPubMed Ho V, Heslin MJ. Effect of hospital volume and experience on in-hospital mortality for pancreaticoduodenectomy. Ann Surg 2003; 237(4):509–14.PubMedCentralPubMed
11.
Zurück zum Zitat Chahal P, Baron TH, Topazian MD, et al. Endoscopic retrograde cholangiopancreatography in post-Whipple patients. Endoscopy 2006; 38(12):1241–5.CrossRefPubMed Chahal P, Baron TH, Topazian MD, et al. Endoscopic retrograde cholangiopancreatography in post-Whipple patients. Endoscopy 2006; 38(12):1241–5.CrossRefPubMed
12.
Zurück zum Zitat Farrell J, Carr-Locke D, Garrido T, et al. Endoscopic retrograde cholangiopancreatography after pancreaticoduodenectomy for benign and malignant disease: indications and technical outcomes. Endoscopy 2006; 38(12):1246–9.CrossRefPubMed Farrell J, Carr-Locke D, Garrido T, et al. Endoscopic retrograde cholangiopancreatography after pancreaticoduodenectomy for benign and malignant disease: indications and technical outcomes. Endoscopy 2006; 38(12):1246–9.CrossRefPubMed
13.
Zurück zum Zitat Gervais DA, Fernandez-del Castillo C, O'Neill MJ, et al. Complications after pancreatoduodenectomy: imaging and imaging-guided interventional procedures. Radiographics 2001; 21(3):673–90.CrossRefPubMed Gervais DA, Fernandez-del Castillo C, O'Neill MJ, et al. Complications after pancreatoduodenectomy: imaging and imaging-guided interventional procedures. Radiographics 2001; 21(3):673–90.CrossRefPubMed
14.
Zurück zum Zitat Sohn TA, Yeo CJ, Cameron JL, et al. Pancreaticoduodenectomy: role of interventional radiologists in managing patients and complications. J Gastrointest Surg 2003; 7(2):209–19.CrossRefPubMed Sohn TA, Yeo CJ, Cameron JL, et al. Pancreaticoduodenectomy: role of interventional radiologists in managing patients and complications. J Gastrointest Surg 2003; 7(2):209–19.CrossRefPubMed
15.
Zurück zum Zitat Kennedy EP, Rosato EL, Sauter PK, et al. Initiation of a critical pathway for pancreaticoduodenectomy at an academic institution—the first step in multidisciplinary team building. J Am Coll Surg 2007; 204(5):917–23; discussion 923–4.CrossRefPubMed Kennedy EP, Rosato EL, Sauter PK, et al. Initiation of a critical pathway for pancreaticoduodenectomy at an academic institution—the first step in multidisciplinary team building. J Am Coll Surg 2007; 204(5):917–23; discussion 923–4.CrossRefPubMed
16.
Zurück zum Zitat Fong ZV, Correa-Gallego C, Ferrone CR, et al. Early drain removal—the middle ground between the drain versus no drain debate in patients undergoing pancreaticoduodenectomy: a prospective validation study. Ann Surg 2015. Fong ZV, Correa-Gallego C, Ferrone CR, et al. Early drain removal—the middle ground between the drain versus no drain debate in patients undergoing pancreaticoduodenectomy: a prospective validation study. Ann Surg 2015.
17.
Zurück zum Zitat Prakash K, Kamalesh NP, Pramil K, et al. Does case selection and outcome following laparoscopic colorectal resection change after initial learning curve? Analysis of 235 consecutive elective laparoscopic colorectal resections. J Minim Access Surg 2013; 9(3):99–103.PubMedCentralCrossRefPubMed Prakash K, Kamalesh NP, Pramil K, et al. Does case selection and outcome following laparoscopic colorectal resection change after initial learning curve? Analysis of 235 consecutive elective laparoscopic colorectal resections. J Minim Access Surg 2013; 9(3):99–103.PubMedCentralCrossRefPubMed
18.
Zurück zum Zitat Fernandez-del Castillo C, Morales-Oyarvide V, McGrath D, et al. Evolution of the Whipple procedure at the Massachusetts General Hospital. Surgery 2012; 152(3 Suppl 1):S56-63.CrossRefPubMed Fernandez-del Castillo C, Morales-Oyarvide V, McGrath D, et al. Evolution of the Whipple procedure at the Massachusetts General Hospital. Surgery 2012; 152(3 Suppl 1):S56-63.CrossRefPubMed
19.
Zurück zum Zitat Winter JM, Cameron JL, Campbell KA, et al. 1423 pancreaticoduodenectomies for pancreatic cancer: a single-institution experience. J Gastrointest Surg 2006; 10(9):1199–210; discussion 1210–1.CrossRefPubMed Winter JM, Cameron JL, Campbell KA, et al. 1423 pancreaticoduodenectomies for pancreatic cancer: a single-institution experience. J Gastrointest Surg 2006; 10(9):1199–210; discussion 1210–1.CrossRefPubMed
20.
Zurück zum Zitat Fernandez-del Castillo C, Rattner DW, Warshaw AL. Standards for pancreatic resection in the 1990s. Arch Surg 1995; 130(3):295–9; discussion 299–300.CrossRefPubMed Fernandez-del Castillo C, Rattner DW, Warshaw AL. Standards for pancreatic resection in the 1990s. Arch Surg 1995; 130(3):295–9; discussion 299–300.CrossRefPubMed
21.
Zurück zum Zitat Trede M, Schwall G, Saeger HD. Survival after pancreatoduodenectomy. 118 consecutive resections without an operative mortality. Ann Surg 1990; 211(4):447–58.PubMedCentralCrossRefPubMed Trede M, Schwall G, Saeger HD. Survival after pancreatoduodenectomy. 118 consecutive resections without an operative mortality. Ann Surg 1990; 211(4):447–58.PubMedCentralCrossRefPubMed
22.
Zurück zum Zitat Syin D, Woreta T, Chang DC, et al. Publication bias in surgery: implications for informed consent. J Surg Res 2007; 143(1):88–93.CrossRefPubMed Syin D, Woreta T, Chang DC, et al. Publication bias in surgery: implications for informed consent. J Surg Res 2007; 143(1):88–93.CrossRefPubMed
23.
Zurück zum Zitat Asiyanbola B, Chang D, Gleisner AL, et al. Operative mortality after hepatic resection: are literature-based rates broadly applicable? J Gastrointest Surg 2008; 12(5):842–51.CrossRefPubMed Asiyanbola B, Chang D, Gleisner AL, et al. Operative mortality after hepatic resection: are literature-based rates broadly applicable? J Gastrointest Surg 2008; 12(5):842–51.CrossRefPubMed
24.
Zurück zum Zitat Birkmeyer JD, Finks JF, O'Reilly A, et al. Surgical skill and complication rates after bariatric surgery. N Engl J Med 2013; 369(15):1434–42.CrossRefPubMed Birkmeyer JD, Finks JF, O'Reilly A, et al. Surgical skill and complication rates after bariatric surgery. N Engl J Med 2013; 369(15):1434–42.CrossRefPubMed
25.
Zurück zum Zitat Fong ZV, Winter JM. Biomarkers in pancreatic cancer: diagnostic, prognostic, and predictive. Cancer J 2012; 18(6):530–8.CrossRefPubMed Fong ZV, Winter JM. Biomarkers in pancreatic cancer: diagnostic, prognostic, and predictive. Cancer J 2012; 18(6):530–8.CrossRefPubMed
26.
Zurück zum Zitat Winter JM, Brennan MF, Tang LH, et al. Survival after resection of pancreatic adenocarcinoma: results from a single institution over three decades. Ann Surg Oncol 2012; 19(1):169–75.CrossRefPubMed Winter JM, Brennan MF, Tang LH, et al. Survival after resection of pancreatic adenocarcinoma: results from a single institution over three decades. Ann Surg Oncol 2012; 19(1):169–75.CrossRefPubMed
27.
Zurück zum Zitat Vickers AJ. What are the implications of the surgical learning curve? Eur Urol 2014; 65(3):532–3.CrossRefPubMed Vickers AJ. What are the implications of the surgical learning curve? Eur Urol 2014; 65(3):532–3.CrossRefPubMed
28.
Zurück zum Zitat Ramsay CR, Grant AM, Wallace SA, et al. Assessment of the learning curve in health technologies. A systematic review. Int J Technol Assess Health Care 2000; 16(4):1095–108.CrossRefPubMed Ramsay CR, Grant AM, Wallace SA, et al. Assessment of the learning curve in health technologies. A systematic review. Int J Technol Assess Health Care 2000; 16(4):1095–108.CrossRefPubMed
29.
Zurück zum Zitat Ramsay CR, Wallace SA, Garthwaite PH, et al. Assessing the learning curve effect in health technologies. Lessons from the nonclinical literature. Int J Technol Assess Health Care 2002; 18(1):1–10.PubMed Ramsay CR, Wallace SA, Garthwaite PH, et al. Assessing the learning curve effect in health technologies. Lessons from the nonclinical literature. Int J Technol Assess Health Care 2002; 18(1):1–10.PubMed
30.
Zurück zum Zitat Schneider EB, Ejaz A, Spolverato G, et al. Hospital volume and patient outcomes in hepato-pancreatico-biliary surgery: is assessing differences in mortality enough? J Gastrointest Surg 2014; 18(12):2105–15.CrossRefPubMed Schneider EB, Ejaz A, Spolverato G, et al. Hospital volume and patient outcomes in hepato-pancreatico-biliary surgery: is assessing differences in mortality enough? J Gastrointest Surg 2014; 18(12):2105–15.CrossRefPubMed
31.
Zurück zum Zitat Hambrick DZ, Oswald FL, Altmann EM, et al. Deliberate practice: is that all it takes to become an expert? Intelligence 2014; 45(0):34–45. Hambrick DZ, Oswald FL, Altmann EM, et al. Deliberate practice: is that all it takes to become an expert? Intelligence 2014; 45(0):34–45.
32.
Zurück zum Zitat Schmidt CM, Turrini O, Parikh P, et al. Effect of hospital volume, surgeon experience, and surgeon volume on patient outcomes after pancreaticoduodenectomy: a single-institution experience. Arch Surg 2010; 145(7):634–40. Schmidt CM, Turrini O, Parikh P, et al. Effect of hospital volume, surgeon experience, and surgeon volume on patient outcomes after pancreaticoduodenectomy: a single-institution experience. Arch Surg 2010; 145(7):634–40.
Metadaten
Titel
Outcomes Improvement Is Not Continuous Along the Learning Curve for Pancreaticoduodenectomy at the Hospital Level
verfasst von
Taylor M. Coe
Zhi Ven Fong
Samuel E. Wilson
Mark A. Talamini
Keith D. Lillemoe
David C. Chang
Publikationsdatum
01.12.2015
Verlag
Springer US
Erschienen in
Journal of Gastrointestinal Surgery / Ausgabe 12/2015
Print ISSN: 1091-255X
Elektronische ISSN: 1873-4626
DOI
https://doi.org/10.1007/s11605-015-2967-0

Weitere Artikel der Ausgabe 12/2015

Journal of Gastrointestinal Surgery 12/2015 Zur Ausgabe

Update Chirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

S3-Leitlinie „Diagnostik und Therapie des Karpaltunnelsyndroms“

Karpaltunnelsyndrom BDC Leitlinien Webinare
CME: 2 Punkte

Das Karpaltunnelsyndrom ist die häufigste Kompressionsneuropathie peripherer Nerven. Obwohl die Anamnese mit dem nächtlichen Einschlafen der Hand (Brachialgia parästhetica nocturna) sehr typisch ist, ist eine klinisch-neurologische Untersuchung und Elektroneurografie in manchen Fällen auch eine Neurosonografie erforderlich. Im Anfangsstadium sind konservative Maßnahmen (Handgelenksschiene, Ergotherapie) empfehlenswert. Bei nicht Ansprechen der konservativen Therapie oder Auftreten von neurologischen Ausfällen ist eine Dekompression des N. medianus am Karpaltunnel indiziert.

Prof. Dr. med. Gregor Antoniadis
Berufsverband der Deutschen Chirurgie e.V.

S2e-Leitlinie „Distale Radiusfraktur“

Radiusfraktur BDC Leitlinien Webinare
CME: 2 Punkte

Das Webinar beschäftigt sich mit Fragen und Antworten zu Diagnostik und Klassifikation sowie Möglichkeiten des Ausschlusses von Zusatzverletzungen. Die Referenten erläutern, welche Frakturen konservativ behandelt werden können und wie. Das Webinar beantwortet die Frage nach aktuellen operativen Therapiekonzepten: Welcher Zugang, welches Osteosynthesematerial? Auf was muss bei der Nachbehandlung der distalen Radiusfraktur geachtet werden?

PD Dr. med. Oliver Pieske
Dr. med. Benjamin Meyknecht
Berufsverband der Deutschen Chirurgie e.V.

S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“

Appendizitis BDC Leitlinien Webinare
CME: 2 Punkte

Inhalte des Webinars zur S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“ sind die Darstellung des Projektes und des Erstellungswegs zur S1-Leitlinie, die Erläuterung der klinischen Relevanz der Klassifikation EAES 2015, die wissenschaftliche Begründung der wichtigsten Empfehlungen und die Darstellung stadiengerechter Therapieoptionen.

Dr. med. Mihailo Andric
Berufsverband der Deutschen Chirurgie e.V.