Erschienen in:
15.11.2019 | Research Methods and Statistical Analyses (Y Le Manach, Section Editor)
Outcomes in Pain Clinical Research: What Really Matters for Patients?
verfasst von:
James S. Khan, Rutvij Shah, Ian Gilron
Erschienen in:
Current Anesthesiology Reports
|
Ausgabe 4/2019
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Abstract
Purpose of Review
The measurement and assessment of pain outcomes is critical to the design, analysis, and interpretation of a pain clinical trial. Results from clinical research impact a number of stakeholders, but it can be argued that patients are the most affected. The purpose of this review is to summarize the most important pain outcomes to patients and discuss methodological considerations in collecting these data in a clinical trial.
Recent Findings
We found that there are a number of outcomes that are important to patients. The outcomes that consistently appear in the literature include reductions in pain intensity, changes in medications, and improvements in physical functioning, sleep, and emotional well-being.
Summary
Further work is needed to identify what patients truly consider important, minimally important changes, and how best to measure and report these outcomes in pain clinical research.