Skip to main content
Erschienen in:

01.01.2018 | Original Article

Outcomes, safety, and feasibility of video-assisted thoracic surgery in lung cancer patients on hemodialysis: a case series

verfasst von: Yuji Otsuki, Hiroaki Kuwahara, Hirofumi Konn

Erschienen in: General Thoracic and Cardiovascular Surgery | Ausgabe 1/2018

Einloggen, um Zugang zu erhalten

Abstract

Objective

The rate of surgical resection of lung cancer in patients on hemodialysis is expected to increase due to the development of hemodialysis, improved diagnosis of lung cancer, and increases in the number and age of patients. However, studies assessing outcomes of lung resection in these patients are limited. In this retrospective case series, we investigated the safety and efficacy of video-assisted thoracic surgery (VATS) for lobectomy or segmentectomy for lung cancer in patients on hemodialysis.

Methods

Between January 2010 and January 2017, lobectomy or segmentectomy using VATS was performed for seven lung cancer cases in six patients receiving hemodialysis at our institution. There were two female and five male patients, with a median age of 61 years (range 53–76 years). Six patients underwent lobectomy, and segmentectomy and wedge resection were performed in each one case, respectively; systematic mediastinal lymph node dissection (ND2a-2) was performed in six patients.

Results

There were no perioperative deaths in this case series. Median recurrence-free and overall survival rates were 20 months (range 3–82 months) and 31 months (range 3–82 months), respectively.

Conclusions

Video-assisted thoracic surgery (VATS) is a safe and effective procedure for resection of lung cancer in hemodialysis patients and should be considered after accurate determination of surgical indications and careful perioperative management.
Literatur
1.
Zurück zum Zitat Scott WJ, Allen MS, Darling G, Meyers B, Decker PA, Putnam JB, et al. Video-assisted thoracic surgery versus open lobectomy for lung cancer: a secondary analysis of data from the American College of Surgeons Oncology Group Z0030 randomized clinical trial. J Thorac Cardiovasc Surg. 2010;139:976–81.CrossRefPubMed Scott WJ, Allen MS, Darling G, Meyers B, Decker PA, Putnam JB, et al. Video-assisted thoracic surgery versus open lobectomy for lung cancer: a secondary analysis of data from the American College of Surgeons Oncology Group Z0030 randomized clinical trial. J Thorac Cardiovasc Surg. 2010;139:976–81.CrossRefPubMed
2.
Zurück zum Zitat Morita T, Tachibana S, Kawakami M, Orino T, Nakao K, Tokitsu K, et al. Pulmonary lobectomy for lung cancer in patients on chronic hemodialysis. Jpn J Chest Surg. 2001;15:454–8.CrossRef Morita T, Tachibana S, Kawakami M, Orino T, Nakao K, Tokitsu K, et al. Pulmonary lobectomy for lung cancer in patients on chronic hemodialysis. Jpn J Chest Surg. 2001;15:454–8.CrossRef
3.
Zurück zum Zitat Villamizar NR, Darrabie MD, Burfeind WR, Petersen RP, Onaitis MW, Toloza E, et al. Thoracoscopic lobectomy is associated with lower morbidity compared with thoracotomy. J Thorac Cardiovasc Surg. 2009;138:419–25.CrossRefPubMed Villamizar NR, Darrabie MD, Burfeind WR, Petersen RP, Onaitis MW, Toloza E, et al. Thoracoscopic lobectomy is associated with lower morbidity compared with thoracotomy. J Thorac Cardiovasc Surg. 2009;138:419–25.CrossRefPubMed
4.
Zurück zum Zitat Obuchi T, Hamanaka W, Yoshida Y, Yanagisawa J, Hamatake D, Shiraishi T, et al. Clinical outcome after pulmonary resection for lung cancer patients on hemodialysis. Ann Thorac Surg. 2009;88:1745–8.CrossRefPubMed Obuchi T, Hamanaka W, Yoshida Y, Yanagisawa J, Hamatake D, Shiraishi T, et al. Clinical outcome after pulmonary resection for lung cancer patients on hemodialysis. Ann Thorac Surg. 2009;88:1745–8.CrossRefPubMed
5.
Zurück zum Zitat Matsuoka K, Kuroda A, Kang A, Imanishi N, Nagai S, Ueda M, et al. Video-assisted thoracoscopic surgery for lung cancer in patients on hemodialysis. Ann Thorac Cardiovasc Surg. 2013;19:263–7.CrossRefPubMed Matsuoka K, Kuroda A, Kang A, Imanishi N, Nagai S, Ueda M, et al. Video-assisted thoracoscopic surgery for lung cancer in patients on hemodialysis. Ann Thorac Cardiovasc Surg. 2013;19:263–7.CrossRefPubMed
6.
Zurück zum Zitat Park BJ, Shin S, Kim HK, Choi YS, Kim J, Shim YM. Surgical treatment for non-small cell lung cancer in patients on hemodialysis due to chronic kidney disease: clinical outcome and intermediate-term results. Korean J Thorac Cardiovasc Surg. 2015;48:193–8.CrossRefPubMedPubMedCentral Park BJ, Shin S, Kim HK, Choi YS, Kim J, Shim YM. Surgical treatment for non-small cell lung cancer in patients on hemodialysis due to chronic kidney disease: clinical outcome and intermediate-term results. Korean J Thorac Cardiovasc Surg. 2015;48:193–8.CrossRefPubMedPubMedCentral
7.
Zurück zum Zitat Akiba T, Marushima H, Hiramatsu M, Matsudaira H, Nakanishi K, Takeyama H, et al. Video-assisted thoracoscopic surgery for non-small cell lung cancer in patients on hemodialysis. Ann Thorac Cardiovasc Surg. 2010;16:40–4.PubMed Akiba T, Marushima H, Hiramatsu M, Matsudaira H, Nakanishi K, Takeyama H, et al. Video-assisted thoracoscopic surgery for non-small cell lung cancer in patients on hemodialysis. Ann Thorac Cardiovasc Surg. 2010;16:40–4.PubMed
8.
Zurück zum Zitat Caroli G, Dolci G, Dell’Amore A, Asadi N, Greco D, Chadi A, et al. Video-assisted thoracoscopic lobectomy for non-small cell lung cancer: a morbidity limiting approach in a patient on chronic hemodialysis and double agent antiplatelet therapy. Gen Thorac Cardiovasc Surg. 2015;63:177–80.CrossRefPubMed Caroli G, Dolci G, Dell’Amore A, Asadi N, Greco D, Chadi A, et al. Video-assisted thoracoscopic lobectomy for non-small cell lung cancer: a morbidity limiting approach in a patient on chronic hemodialysis and double agent antiplatelet therapy. Gen Thorac Cardiovasc Surg. 2015;63:177–80.CrossRefPubMed
9.
Zurück zum Zitat Ciriaco P, Casiraghi M, Melloni G, Carretta A, Libretti L, Augello G, et al. Pulmonary resection for non-small-cell lung cancer in patients on hemodialysis: clinical outcome and long-term results. World J Surg. 2005;29:1516–9.CrossRefPubMed Ciriaco P, Casiraghi M, Melloni G, Carretta A, Libretti L, Augello G, et al. Pulmonary resection for non-small-cell lung cancer in patients on hemodialysis: clinical outcome and long-term results. World J Surg. 2005;29:1516–9.CrossRefPubMed
10.
Zurück zum Zitat Maisonneuve P, Agodoa L, Gellert R, Stewart JH, Buccianti G, Lowenfels AB, et al. Cancer in patients on dialysis for end-stage renal disease: an international collaborative study. Lancet. 1999;354:93–9.CrossRefPubMed Maisonneuve P, Agodoa L, Gellert R, Stewart JH, Buccianti G, Lowenfels AB, et al. Cancer in patients on dialysis for end-stage renal disease: an international collaborative study. Lancet. 1999;354:93–9.CrossRefPubMed
11.
Zurück zum Zitat Takahama M, Yamamoto R, Nakajima R, Tsukioka T, Tada H. Pulmonary resection for lung cancer patients on chronic hemodialysis: clinical outcome and long-term results after operation. Interact Cardiovasc Thorac Surg. 2010;11:150–3.CrossRefPubMed Takahama M, Yamamoto R, Nakajima R, Tsukioka T, Tada H. Pulmonary resection for lung cancer patients on chronic hemodialysis: clinical outcome and long-term results after operation. Interact Cardiovasc Thorac Surg. 2010;11:150–3.CrossRefPubMed
12.
Zurück zum Zitat Tsuchida M, Yamato Y, Aoki T, Watanabe T, Hashimoto T, Shinohara H, et al. Complications associated with pulmonary resection in lung cancer patients on dialysis. Ann Thorac Surg. 2001;71:435–8.CrossRefPubMed Tsuchida M, Yamato Y, Aoki T, Watanabe T, Hashimoto T, Shinohara H, et al. Complications associated with pulmonary resection in lung cancer patients on dialysis. Ann Thorac Surg. 2001;71:435–8.CrossRefPubMed
13.
Zurück zum Zitat Pinson CW, Schuman ES, Gross GF, Schuman TA, Hayes JF. Surgery in long-term dialysis patients. Experience with more than 300 cases. Am J Surg. 1986;151:567–71.CrossRefPubMed Pinson CW, Schuman ES, Gross GF, Schuman TA, Hayes JF. Surgery in long-term dialysis patients. Experience with more than 300 cases. Am J Surg. 1986;151:567–71.CrossRefPubMed
14.
Zurück zum Zitat Toh Y, Yano K, Takesue F, Korenaga D, Maekawa S, Muto Y, et al. Abdominal surgery for patients on maintenance hemodialysis. Surg Today. 1998;28:268–72.CrossRefPubMed Toh Y, Yano K, Takesue F, Korenaga D, Maekawa S, Muto Y, et al. Abdominal surgery for patients on maintenance hemodialysis. Surg Today. 1998;28:268–72.CrossRefPubMed
15.
Zurück zum Zitat Schneider CR, Cobb W, Patel S, Cull D, Anna C, Roettger R. Elective surgery in patients with end stage renal disease: what’s the risk? Am Surg. 2009;75:790–3.PubMed Schneider CR, Cobb W, Patel S, Cull D, Anna C, Roettger R. Elective surgery in patients with end stage renal disease: what’s the risk? Am Surg. 2009;75:790–3.PubMed
16.
Zurück zum Zitat Akizawa T, Koshikawa S, Ota K, Kazama M, Mimura N, Hirasawa Y. Nafamostat mesilate: a regional anticoagulant for hemodialysis in patients at high risk for bleeding. Nephron. 1993;64:376–81.CrossRefPubMed Akizawa T, Koshikawa S, Ota K, Kazama M, Mimura N, Hirasawa Y. Nafamostat mesilate: a regional anticoagulant for hemodialysis in patients at high risk for bleeding. Nephron. 1993;64:376–81.CrossRefPubMed
17.
18.
Zurück zum Zitat Maeda S, Okada Y, Kondo T. Lung resection for lung cancer patients on hemodialysis. Kyobu Geka. 2012;65:724–7.PubMed Maeda S, Okada Y, Kondo T. Lung resection for lung cancer patients on hemodialysis. Kyobu Geka. 2012;65:724–7.PubMed
19.
Zurück zum Zitat Lee HK, Kim YJ, Jeong JU, Park JS, Chi HS, Kim SB. Desmopressin improves platelet dysfunction measured by in vitro closure time in uremic patients. Nephron Clin Pract. 2010;114:248–52.CrossRef Lee HK, Kim YJ, Jeong JU, Park JS, Chi HS, Kim SB. Desmopressin improves platelet dysfunction measured by in vitro closure time in uremic patients. Nephron Clin Pract. 2010;114:248–52.CrossRef
20.
Zurück zum Zitat Diaz-Ricart M, Etebanell E, Cases A, López-Pedret J, Castillo R, Ordinas A, et al. Erythropoietin improves signaling through tyrosine phosphorylation in platelets from uremic patients. Thromb Haemost. 1999;82:1312–7.PubMed Diaz-Ricart M, Etebanell E, Cases A, López-Pedret J, Castillo R, Ordinas A, et al. Erythropoietin improves signaling through tyrosine phosphorylation in platelets from uremic patients. Thromb Haemost. 1999;82:1312–7.PubMed
21.
Zurück zum Zitat Enokibara T, Katsura A, Yagisawa M, Yasuda Y, Kato H, Mori A. Lung cancer resection in a patient with chronic renal failure on long-term hemodialysis. Jpn J Lung Cancer. 1991;31:421–26.CrossRef Enokibara T, Katsura A, Yagisawa M, Yasuda Y, Kato H, Mori A. Lung cancer resection in a patient with chronic renal failure on long-term hemodialysis. Jpn J Lung Cancer. 1991;31:421–26.CrossRef
22.
Zurück zum Zitat Suehiro K, Okutani R. Perioperative complications in patients with end-stage renal disease undergoing pulmonary resection. J Anesth Clin Res. 2011;2:127.CrossRef Suehiro K, Okutani R. Perioperative complications in patients with end-stage renal disease undergoing pulmonary resection. J Anesth Clin Res. 2011;2:127.CrossRef
23.
Zurück zum Zitat Obuchi T, Saito T, Iwasaki A. Frequency of multiple primary cancers in the lung and other organs in hemodialysis patients. Gen Thorac Cardiovasc Surg. 2012;60:489–93.CrossRefPubMed Obuchi T, Saito T, Iwasaki A. Frequency of multiple primary cancers in the lung and other organs in hemodialysis patients. Gen Thorac Cardiovasc Surg. 2012;60:489–93.CrossRefPubMed
24.
Zurück zum Zitat Obara T, Ohnuki T, Yuasa S, Quian Y, Nitta S. Clinical study about perioperative management and indication of operation in lung cancer patients with chronic renal failure. J Tokyo Women Med Univ. 2000;70:777–83. Obara T, Ohnuki T, Yuasa S, Quian Y, Nitta S. Clinical study about perioperative management and indication of operation in lung cancer patients with chronic renal failure. J Tokyo Women Med Univ. 2000;70:777–83.
25.
Zurück zum Zitat Eneman JD, Philips GK. Cancer management in patients with end-stage renal disease. Int Soc Cell. 2005;19:1199–212. Eneman JD, Philips GK. Cancer management in patients with end-stage renal disease. Int Soc Cell. 2005;19:1199–212.
Metadaten
Titel
Outcomes, safety, and feasibility of video-assisted thoracic surgery in lung cancer patients on hemodialysis: a case series
verfasst von
Yuji Otsuki
Hiroaki Kuwahara
Hirofumi Konn
Publikationsdatum
01.01.2018
Verlag
Springer Japan
Erschienen in
General Thoracic and Cardiovascular Surgery / Ausgabe 1/2018
Print ISSN: 1863-6705
Elektronische ISSN: 1863-6713
DOI
https://doi.org/10.1007/s11748-017-0847-0

Neu im Fachgebiet Chirurgie

Höhere Dosis von Dexamethason senkt Überlebenschancen

Personen mit Hirnmetastasen, die perioperativ höhere kumulative Dosen von Dexamethason erhalten, haben eine schlechtere Prognose. Um die Ergebnisse zu verbessern, bedarf es strengerer Dosierungsschemata.

Appendektomie erhält Remission bei Colitis ulcerosa

Wird der Wurmfortsatz bei Personen mit Colitis ulcerosa entfernt, ist die Rückfallrate um ein Drittel geringer als unter konservativer Behandlung. Auch die Lebensqualität verbessert sich und der Bedarf an Medikamenten nimmt ab.

Op.-Entscheidung bei Divertikulitis: Lebensqualität zählt!

Soll man Menschen, die schon mehrfach schmerzhafte Divertikulitisepisoden durchgemacht haben, eine Op. anbieten? Ein Team aus Helsinki rät, dies von der Lebensqualität abhängig zu machen.

Akute Cholezystitis bei multimorbiden Älteren: Operation nicht sofort ausschließen!

Bei älteren, multimorbiden Menschen mit akuter Cholezystitis wird eine Operation häufig nicht erwogen. Eine Studie aus Philadelphia zeigt nun jedoch, dass auch diese Patientinnen und Patienten von einer chirurgischen Therapie profitieren können.

Update Chirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.