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Erschienen in: The journal of nutrition, health & aging 4/2019

19.02.2019

Overwhelming Underuse of Bisphosphonates in French Nursing Home Residents After Proximal Femoral Fracture

verfasst von: Paul Le Floch, P. Kermarrec, A. Gentric

Erschienen in: The journal of nutrition, health & aging | Ausgabe 4/2019

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Abstract

Objective

To evaluate the prescription of bisphosphonates in female nursing home residents aged 75 and older with a history of proximal femoral fracture.

Design

Observational descriptive study, led in Brest, France, between June and August 2015.

Setting

12 nursing homes in Brest, France.

Participants

Female nursing home residents, aged 75 and older, with a history of proximal femoral fracture were included. Exclusion criteria were contraindications to bisphosphonate treatment and residents restricted to bed and chair.

Measurements

The primary endpoint was the evaluation of prescription of bisphosphonates at the time of the study. The secondary endpoints were to evaluate vitamin D supplementation and factors associated with bisphosphonate prescription.

Results

12 of the 116 included residents (10.3 %) received bisphosphonates. 66.4 % received vitamin D supplementation.

Conclusion

Despite successive French and international recommendations, there is still a very important underuse of treatment by bisphosphonates in old institutionalized female patients with a very high risk of fracture.
Literatur
2.
Zurück zum Zitat Briot, K, Maravic, M, Roux, C. Changes in number and incidence of hip fractures over 12 years in France. Bone. 2015 Dec;81:131–7.CrossRefPubMed Briot, K, Maravic, M, Roux, C. Changes in number and incidence of hip fractures over 12 years in France. Bone. 2015 Dec;81:131–7.CrossRefPubMed
3.
Zurück zum Zitat Bliuc, D, Nguyen, ND, Milch, VE, Nguyen, TV, Eisman, JA, Center, JR. Mortality risk associated with low-trauma osteoporotic fracture and subsequent fracture in men and women. JAMA. 2009 Feb 4;301(5):513–21.CrossRefPubMed Bliuc, D, Nguyen, ND, Milch, VE, Nguyen, TV, Eisman, JA, Center, JR. Mortality risk associated with low-trauma osteoporotic fracture and subsequent fracture in men and women. JAMA. 2009 Feb 4;301(5):513–21.CrossRefPubMed
4.
Zurück zum Zitat Oleksik, A, Lips, P, Dawson, A, Minshall, ME, Shen, W, Cooper, C, et al. Healthrelated quality of life in postmenopausal women with low BMD with or without prevalent vertebral fractures. J Bone Miner Res Off J Am Soc Bone Miner Res. 2000 Jul;15(7):1384–92.CrossRef Oleksik, A, Lips, P, Dawson, A, Minshall, ME, Shen, W, Cooper, C, et al. Healthrelated quality of life in postmenopausal women with low BMD with or without prevalent vertebral fractures. J Bone Miner Res Off J Am Soc Bone Miner Res. 2000 Jul;15(7):1384–92.CrossRef
5.
Zurück zum Zitat Cauley, JA, Thompson, DE, Ensrud, KC, Scott, JC, Black, D. Risk of mortality following clinical fractures. Osteoporos Int J Establ Result Coop Eur Found Osteoporos Natl Osteoporos Found USA. 2000;11(7):556–61.CrossRef Cauley, JA, Thompson, DE, Ensrud, KC, Scott, JC, Black, D. Risk of mortality following clinical fractures. Osteoporos Int J Establ Result Coop Eur Found Osteoporos Natl Osteoporos Found USA. 2000;11(7):556–61.CrossRef
6.
Zurück zum Zitat Lindsay, R, Silverman, SL, Cooper, C, Hanley, DA, Barton, I, Broy, SB, et al. Risk of new vertebral fracture in the year following a fracture. JAMA. 2001 Jan 17;285(3):320–3.CrossRefPubMed Lindsay, R, Silverman, SL, Cooper, C, Hanley, DA, Barton, I, Broy, SB, et al. Risk of new vertebral fracture in the year following a fracture. JAMA. 2001 Jan 17;285(3):320–3.CrossRefPubMed
8.
Zurück zum Zitat Briot, K, Roux, C, Thomas, T, Blain, H, Buchon, D, Chapurlat, R, et al. 2018 update of French recommendations on the management of postmenopausal osteoporosis. Jt Bone Spine Rev Rhum. 2018 Apr 11 Briot, K, Roux, C, Thomas, T, Blain, H, Buchon, D, Chapurlat, R, et al. 2018 update of French recommendations on the management of postmenopausal osteoporosis. Jt Bone Spine Rev Rhum. 2018 Apr 11
9.
Zurück zum Zitat Tuck, S, Little, EA, Aspray, TJ. Implications of guidelines for osteoporosis and its treatment. Age Ageing. 2018 May 1;47(3):334–9.CrossRefPubMed Tuck, S, Little, EA, Aspray, TJ. Implications of guidelines for osteoporosis and its treatment. Age Ageing. 2018 May 1;47(3):334–9.CrossRefPubMed
10.
Zurück zum Zitat Aguilar, EA, Barry, SD, Cefalu, CA, Abdo, A, Hudson, WP, Campbell, JS, et al. Osteoporosis Diagnosis and Management in Long-Term Care Facility. Am J Med Sci. 2015 Nov;350(5):357–63.CrossRefPubMed Aguilar, EA, Barry, SD, Cefalu, CA, Abdo, A, Hudson, WP, Campbell, JS, et al. Osteoporosis Diagnosis and Management in Long-Term Care Facility. Am J Med Sci. 2015 Nov;350(5):357–63.CrossRefPubMed
11.
Zurück zum Zitat Zarowitz, BJ, Cheng L-I, Allen, C, O’Shea, T, Stolshek, B. Osteoporosis prevalence and characteristics of treated and untreated nursing home residents with osteoporosis. J Am Med Dir Assoc. 2015 Apr;16(4):341–8.CrossRefPubMed Zarowitz, BJ, Cheng L-I, Allen, C, O’Shea, T, Stolshek, B. Osteoporosis prevalence and characteristics of treated and untreated nursing home residents with osteoporosis. J Am Med Dir Assoc. 2015 Apr;16(4):341–8.CrossRefPubMed
12.
Zurück zum Zitat Sambrook, PN, Cameron, ID, Chen, JS, March, LM, Simpson, JM, Cumming, RG, et al. Oral bisphosphonates are associated with reduced mortality in frail older people: a prospective five-year study. Osteoporos Int. 2011 Sep;22(9):2551–6.CrossRefPubMed Sambrook, PN, Cameron, ID, Chen, JS, March, LM, Simpson, JM, Cumming, RG, et al. Oral bisphosphonates are associated with reduced mortality in frail older people: a prospective five-year study. Osteoporos Int. 2011 Sep;22(9):2551–6.CrossRefPubMed
13.
Zurück zum Zitat Bouvet, A, Sabatier, B, Savoldelli, V, Caruba, T, Pouchot, J. Evaluation of the prescription of osteoporosis treatment after a major osteoporotic fracture. J Clin Rheumatol Pract Rep Rheum Musculoskelet Dis. 2014 Sep;20(6):347–8. Bouvet, A, Sabatier, B, Savoldelli, V, Caruba, T, Pouchot, J. Evaluation of the prescription of osteoporosis treatment after a major osteoporotic fracture. J Clin Rheumatol Pract Rep Rheum Musculoskelet Dis. 2014 Sep;20(6):347–8.
14.
Zurück zum Zitat Parikh, S, Brookhart, MA, Stedman, M, Avorn, J, Mogun, H, Solomon, DH. Correlations of nursing home characteristics with prescription of osteoporosis medications. Bone. 2011 May 1;48(5):1164–8.CrossRefPubMedPubMedCentral Parikh, S, Brookhart, MA, Stedman, M, Avorn, J, Mogun, H, Solomon, DH. Correlations of nursing home characteristics with prescription of osteoporosis medications. Bone. 2011 May 1;48(5):1164–8.CrossRefPubMedPubMedCentral
15.
Zurück zum Zitat Colón-Emeric, C, Lyles, K, Levine, D, House, P, Schenck, A, Gorospe, J, et al. Prevalence and Predictors of Osteoporosis Treatment in Nursing Home Residents with Known Osteoporosis or Recent Fracture. Osteoporos Int J Establ Result Coop Eur Found Osteoporos Natl Osteoporos Found USA. 2007 Apr;18(4):553–9.CrossRef Colón-Emeric, C, Lyles, K, Levine, D, House, P, Schenck, A, Gorospe, J, et al. Prevalence and Predictors of Osteoporosis Treatment in Nursing Home Residents with Known Osteoporosis or Recent Fracture. Osteoporos Int J Establ Result Coop Eur Found Osteoporos Natl Osteoporos Found USA. 2007 Apr;18(4):553–9.CrossRef
16.
Zurück zum Zitat Cortet, B, Bénichou, O. Adhérence, observance, persistance, concordance: prenonsnous en charge correctement nos patientes ostéoporotiques? Rev Rhum. 2006 Oct;73(9):e1–9.CrossRef Cortet, B, Bénichou, O. Adhérence, observance, persistance, concordance: prenonsnous en charge correctement nos patientes ostéoporotiques? Rev Rhum. 2006 Oct;73(9):e1–9.CrossRef
17.
Zurück zum Zitat Kamel, HK. Underutilization of calcium and vitamin D supplements in an academic long-term care facility. J Am Med Dir Assoc. 2004 Apr;5(2):98–100.CrossRefPubMed Kamel, HK. Underutilization of calcium and vitamin D supplements in an academic long-term care facility. J Am Med Dir Assoc. 2004 Apr;5(2):98–100.CrossRefPubMed
18.
Zurück zum Zitat Duque, G, Lord, SR, Mak, J, Ganda, K, Close, JJT, Ebeling, P, et al. Treatment of Osteoporosis in Australian Residential Aged Care Facilities: Update on Consensus Recommendations for Fracture Prevention. J Am Med Dir Assoc. 2016 Sep 1;17(9):852–9.CrossRefPubMedPubMedCentral Duque, G, Lord, SR, Mak, J, Ganda, K, Close, JJT, Ebeling, P, et al. Treatment of Osteoporosis in Australian Residential Aged Care Facilities: Update on Consensus Recommendations for Fracture Prevention. J Am Med Dir Assoc. 2016 Sep 1;17(9):852–9.CrossRefPubMedPubMedCentral
19.
Zurück zum Zitat Papaioannou, A, Santesso, N, Morin, SN, Feldman, S, Adachi, JD, Crilly, R, et al. Recommendations for preventing fracture in long-term care. CMAJ Can Med Assoc J J Assoc Medicale Can. 2015 Oct 20;187(15):1135–44, E450–61.CrossRef Papaioannou, A, Santesso, N, Morin, SN, Feldman, S, Adachi, JD, Crilly, R, et al. Recommendations for preventing fracture in long-term care. CMAJ Can Med Assoc J J Assoc Medicale Can. 2015 Oct 20;187(15):1135–44, E450–61.CrossRef
Metadaten
Titel
Overwhelming Underuse of Bisphosphonates in French Nursing Home Residents After Proximal Femoral Fracture
verfasst von
Paul Le Floch
P. Kermarrec
A. Gentric
Publikationsdatum
19.02.2019
Verlag
Springer Paris
Erschienen in
The journal of nutrition, health & aging / Ausgabe 4/2019
Print ISSN: 1279-7707
Elektronische ISSN: 1760-4788
DOI
https://doi.org/10.1007/s12603-019-1169-y

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