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Erschienen in: Current Cardiovascular Imaging Reports 2/2013

01.04.2013 | Cardiac Magnetic Resonance (E Nagel, Section Editor)

Oxygenation and Flow in the Limbs: Novel Methods to Characterize Peripheral Artery Disease

verfasst von: David Lopez, Christopher M. Kramer

Erschienen in: Current Cardiovascular Imaging Reports | Ausgabe 2/2013

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Abstract

Peripheral artery disease (PAD) affects approximately 8 million Americans and is associated with high morbidity and increased mortality. Current therapies for PAD are limited and development of new therapeutic agents is needed. Present diagnostic methods for PAD are insensitive to the subtle microvascular and metabolic changes that occur beyond macrovacular stenosis and therefore may be less useful endpoints for clinical trials. Phosphorus-31 magnetic resonance (MR) spectroscopy, MR muscle perfusion, and MR oximetry are novel methods capable of evaluating both the macrovascular and microvascular changes that occur in PAD patients.
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Metadaten
Titel
Oxygenation and Flow in the Limbs: Novel Methods to Characterize Peripheral Artery Disease
verfasst von
David Lopez
Christopher M. Kramer
Publikationsdatum
01.04.2013
Verlag
Current Science Inc.
Erschienen in
Current Cardiovascular Imaging Reports / Ausgabe 2/2013
Print ISSN: 1941-9066
Elektronische ISSN: 1941-9074
DOI
https://doi.org/10.1007/s12410-013-9191-7

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