Erschienen in:
Open Access
01.12.2018 | Protocol
Pain rewarded: hyperalgesic and allodynic effect of operant conditioning in healthy humans—protocol for a systematic review and meta-analysis
verfasst von:
Wacław M. Adamczyk, Kerstin Luedtke, Ewa Buglewicz, Przemysław Bąbel
Erschienen in:
Systematic Reviews
|
Ausgabe 1/2018
Abstract
Background
‘Pain rewarded’ is a hypothesis wherein acute pain sufferers are exposed to reinforcers and punishers from their environment that shape their behaviour, i.e. pain responses. Such a point of view has been taken for granted by many clinicians and researchers although existing evidence has not yet been systematically summarized. This planned systematic review and meta-analysis is aiming to summarize the research findings on pain modulation (hyperalgesic effect) and pain elicitation (allodynic effect) resulting from operant conditioning procedures in healthy humans.
Methods
The systematic review will be performed by searching for articles indexed in PubMed database, Cochrane Register of Controlled Trials (CENTRAL), Web of Science™, ScienceDirect, EBSCO database, PsycINFO, MEDLINE, PsycARTICLES and CINAHL. Studies will be included if they investigate healthy humans, exposed to modulation or elicitation of a pain experience induced by operant conditioning. Studies will be screened for eligibility and risk of bias by two independent assessors. Narrative and meta-analytical syntheses are planned.
Discussion
Data will be pooled and analyzed qualitatively and quantitatively (if possible) in order to advance the understanding of pain mechanisms, especially the development of chronic pain. This systematic review will guide the planning of future experiments and research by summarizing important technical details of conditioning procedures in healthy humans.
Systematic review registration