The authors have no conflicts of interest to declare. This study has no financial relationship with any organization that sponsored the research and authorship. The corresponding author has full control of all primary data and will allow the journal to review the data if requested.
XLG drafted the paper and performed the main statistical analyses. WWC supervised the study, reviewed the analysis, and revised the manuscript. All authors contributed to study design. MLC and MHL reviewed the charts, collected the data, and analysed the qualitative data. ZZ provided extensive background knowledge and participated in the discussion of the results. All authors read, approved and contributed to the final paper. WWC takes responsibility for the manuscript.
There are a number of studies dedicated to characteristics of sedation, but these studies are mostly bound to western country practices. The aim of this study is to describe the characteristics of patients who suffered from cancer and who had been sedated until their death in Shanghai, China.
Retrospective medical data of 244 terminally ill cancer patients including 82 sedated patients were collected. Data collected included demographic characteristics, disease-related characteristics and details of the sedation.
In sedated cases, patients and/or caregivers gave the consent to start palliative sedation due to unmanageable symptoms. On average, sedation was performed 24.65(±1.78)hours before death. Agitated delirium and dyspnea were the most frequent indications for palliative sedation. There was no significant difference in survival time from admission till death between sedated and non-sedated patients (p > 0.05).
Palliative sedation is effective for reducing terminally ill cancer patients’ suffering without hastening death. Prospective research is needed to determine the optimal conditions for Chinese patients including indications, decision making process, informed consent, cultural and ethical issues, type of sedation and drugs.
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- Palliative sedation for terminally ill cancer patients in a tertiary cancer center in Shanghai, China
- BioMed Central
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