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01.03.2012 | Topics | Ausgabe 2/2012

Journal of Hepato-Biliary-Pancreatic Sciences 2/2012

Pancreaticoduodenectomy for invasive pancreatic cancer (with video)

Journal of Hepato-Biliary-Pancreatic Sciences > Ausgabe 2/2012
Hidenori Takahashi, Hiroaki Ohigashi, Osamu Ishikawa
Wichtige Hinweise

Electronic supplementary material

The online version of this article (doi:10.​1007/​s00534-011-0467-5) contains supplementary material, which is available to authorized users.
This article is based on studies first reported in Highly Advanced Surgery for Hepato-Biliary-Pancreatic Field (in Japanese). Tokyo: Igaku-Shoin, 2010.


Pancreaticoduodenectomy (PD) is the only treatment option that potentially provides a cure for pancreatic head cancer. Various arrangements and modifications have been proposed to achieve pathological margin negative (R0) resection safely. In this article, we introduce a standard procedure for PD, including pancreaticogastrostomy with invagination and mattress sutures (video clip provided), for invasive ductal carcinoma of the pancreatic head, with a description of the need-to-know pitfalls for Board-certified HBP surgeons in Japan. The important points in performing PD for pancreatic cancer are: (1) While dissecting connective tissue and nerve plexus as well as lymph nodes, maintain a dissection plane to expose the surfaces of vessels or other organs to be preserved to achieve R0 resection: i.e., while dissecting the anterior surface of the inferior vena cava and the right side of the superior mesenteric artery, these vessels should be completely exposed with the connective tissue and nerve plexuses being attached to the resection side. (2) There should be early interruption of the afferent blood supply via the inferior pancreaticoduodenal artery to reduce blood loss by avoiding congestion of the pancreatic head and to increase the operative safety (video clip provided). (3) Eligibility for PD should be carefully evaluated because there are many “resectable” but not many “curable” cases. In addition, the clinical significance of various modifications of the surgical techniques used for PD are also discussed.

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