Skip to main content
Erschienen in: Die Chirurgie 11/2017

25.08.2017 | Minimalinvasive Chirurgie | Leitthema

Minimalinvasive und roboterassistierte Chirurgie bei zystischen Pankreastumoren

verfasst von: Prof. Dr. T. Welsch, M. Distler, J. Weitz

Erschienen in: Die Chirurgie | Ausgabe 11/2017

Einloggen, um Zugang zu erhalten

Zusammenfassung

Hintergrund

Die Indikationsstellung zur chirurgischen Resektion zystischer Pankreastumoren ist komplex und das operative Risiko für den Patienten muss häufig gegenüber dem Risiko einer malignen Entartung abgewogen werden. Ziel der Arbeit ist ein Überblick über die Ergebnisse der minimalinvasiven Operationstechniken bei zystischen Pankreastumoren.

Methoden

Es erfolgte eine orientierende, systematische Literatursuche unter Verwendung der Medline-Datenbank (PubMed) sowie eine selektive Übersichtsdarstellung.

Ergebnisse

Es liegen bisher keine randomisierten kontrollierten Studien zum Vergleich der offenen und minimalinvasiven Resektion zystischer Tumoren vor. Retrospektive Fallserien bescheinigen den minimalinvasiven Techniken die Machbarkeit und Sicherheit sowie eine vergleichbare Morbidität nach distaler Pankreatektomie (DP), Pankreatoduodenektomie (PD), zentraler (CP) und totaler Pankreatektomie sowie der Enukleation. Während die meisten DP laparoskopisch durchgeführt werden, ist die Erfahrung für die minimalinvasive PD mit dem Roboter größer, jedoch auf wenige spezialisierte Zentren verteilt. Insgesamt ist die Zahl der publizierten Fälle minimalinvasiver organsparender Pankreasresektionen (CP oder Enukleation) bei zystischen Tumoren sehr gering; die verfügbaren selektionierten Ergebnisse jedoch zunächst positiv.

Diskussion

Die minimalinvasive Chirurgie bei zystischen Pankreastumoren hat das Potenzial, das operative Trauma der Patienten bei gleichen oder geringeren Komplikationsraten zu reduzieren. Voraussetzung ist eine zunehmende Spezialisierung insbesondere bei komplexen Operationen. Bei diesen Eingriffen wird der klinische Einsatz des Roboters ansteigen. Eine prospektive Dokumentation der Ergebnisse ist im Rahmen der Qualitätssicherung anzustreben.
Literatur
1.
Zurück zum Zitat Abood GJ, Can MF, Daouadi M et al (2013) Robotic-assisted minimally invasive central pancreatectomy: technique and outcomes. J Gastrointest Surg 17:1002–1008CrossRefPubMed Abood GJ, Can MF, Daouadi M et al (2013) Robotic-assisted minimally invasive central pancreatectomy: technique and outcomes. J Gastrointest Surg 17:1002–1008CrossRefPubMed
2.
Zurück zum Zitat Adam MA, Choudhury K, Dinan MA et al (2015) Minimally invasive versus open pancreaticoduodenectomy for cancer: practice patterns and short-term outcomes among 7061 patients. Ann Surg 262:372–377CrossRefPubMed Adam MA, Choudhury K, Dinan MA et al (2015) Minimally invasive versus open pancreaticoduodenectomy for cancer: practice patterns and short-term outcomes among 7061 patients. Ann Surg 262:372–377CrossRefPubMed
3.
Zurück zum Zitat Asbun HJ, Stauffer JA (2012) Laparoscopic vs open pancreaticoduodenectomy: overall outcomes and severity of complications using the Accordion Severity Grading System. J Am Coll Surg 215:810–819CrossRefPubMed Asbun HJ, Stauffer JA (2012) Laparoscopic vs open pancreaticoduodenectomy: overall outcomes and severity of complications using the Accordion Severity Grading System. J Am Coll Surg 215:810–819CrossRefPubMed
4.
Zurück zum Zitat Balzano G, Carvello M, Piemonti L et al (2014) Combined laparoscopic spleen-preserving distal pancreatectomy and islet autotransplantation for benign pancreatic neoplasm. World J Gastroenterol 20:4030–4036CrossRefPubMedPubMedCentral Balzano G, Carvello M, Piemonti L et al (2014) Combined laparoscopic spleen-preserving distal pancreatectomy and islet autotransplantation for benign pancreatic neoplasm. World J Gastroenterol 20:4030–4036CrossRefPubMedPubMedCentral
5.
Zurück zum Zitat Boone BA, Zenati M, Hogg ME et al (2015) Assessment of quality outcomes for robotic pancreaticoduodenectomy: identification of the learning curve. JAMA Surg 150:416–422CrossRefPubMed Boone BA, Zenati M, Hogg ME et al (2015) Assessment of quality outcomes for robotic pancreaticoduodenectomy: identification of the learning curve. JAMA Surg 150:416–422CrossRefPubMed
6.
Zurück zum Zitat Butturini G, Damoli I, Crepaz L et al (2015) A prospective non-randomised single-center study comparing laparoscopic and robotic distal pancreatectomy. Surg Endosc 29:3163–3170CrossRefPubMed Butturini G, Damoli I, Crepaz L et al (2015) A prospective non-randomised single-center study comparing laparoscopic and robotic distal pancreatectomy. Surg Endosc 29:3163–3170CrossRefPubMed
7.
Zurück zum Zitat Cavallini A, Alvise C, Butturini G et al (2011) Laparoscopic pancreatectomy for solid pseudo-papillary tumors of the pancreas is a suitable technique; our experience with long-term follow-up and review of the literature. Ann Surg Oncol 18:352–357CrossRefPubMed Cavallini A, Alvise C, Butturini G et al (2011) Laparoscopic pancreatectomy for solid pseudo-papillary tumors of the pancreas is a suitable technique; our experience with long-term follow-up and review of the literature. Ann Surg Oncol 18:352–357CrossRefPubMed
8.
Zurück zum Zitat Chapman BC, Paniccia A, Ryan C et al (2017) Laparoscopic spleen-preserving total pancreatectomy for a main-duct Intraductal papillary mucinous neoplasm. Ann Surg Oncol 24:560CrossRefPubMed Chapman BC, Paniccia A, Ryan C et al (2017) Laparoscopic spleen-preserving total pancreatectomy for a main-duct Intraductal papillary mucinous neoplasm. Ann Surg Oncol 24:560CrossRefPubMed
9.
Zurück zum Zitat Croome KP, Farnell MB, Que FG et al (2014) Total laparoscopic pancreaticoduodenectomy for pancreatic ductal adenocarcinoma: oncologic advantages over open approaches? Ann Surg 260:633–638 (discussion 638–40)CrossRefPubMed Croome KP, Farnell MB, Que FG et al (2014) Total laparoscopic pancreaticoduodenectomy for pancreatic ductal adenocarcinoma: oncologic advantages over open approaches? Ann Surg 260:633–638 (discussion 638–40)CrossRefPubMed
10.
Zurück zum Zitat Croome KP, Farnell MB, Que FG et al (2015) Pancreaticoduodenectomy with major vascular resection: a comparison of laparoscopic versus open approaches. J Gastrointest Surg 19:189–194 (discussion 194)CrossRefPubMed Croome KP, Farnell MB, Que FG et al (2015) Pancreaticoduodenectomy with major vascular resection: a comparison of laparoscopic versus open approaches. J Gastrointest Surg 19:189–194 (discussion 194)CrossRefPubMed
11.
Zurück zum Zitat Cunningham KE, Zenati MS, Petrie JR et al (2016) A policy of omitting an intensive care unit stay after robotic pancreaticoduodenectomy is safe and cost-effective. J Surg Res 204:8–14CrossRefPubMed Cunningham KE, Zenati MS, Petrie JR et al (2016) A policy of omitting an intensive care unit stay after robotic pancreaticoduodenectomy is safe and cost-effective. J Surg Res 204:8–14CrossRefPubMed
12.
Zurück zum Zitat Daouadi M, Zureikat AH, Zenati MS et al (2013) Robot-assisted minimally invasive distal pancreatectomy is superior to the laparoscopic technique. Ann Surg 257:128–132CrossRefPubMed Daouadi M, Zureikat AH, Zenati MS et al (2013) Robot-assisted minimally invasive distal pancreatectomy is superior to the laparoscopic technique. Ann Surg 257:128–132CrossRefPubMed
13.
Zurück zum Zitat Dokmak S, Aussilhou B, Rasoaherinomenjanahary F et al (2015) Laparoscopic fenestration of pancreatic serous cystadenoma: Minimally invasive approach for symptomatic benign disease. World J Gastroenterol 21:7047–7051CrossRefPubMedPubMedCentral Dokmak S, Aussilhou B, Rasoaherinomenjanahary F et al (2015) Laparoscopic fenestration of pancreatic serous cystadenoma: Minimally invasive approach for symptomatic benign disease. World J Gastroenterol 21:7047–7051CrossRefPubMedPubMedCentral
14.
Zurück zum Zitat Fernández-Cruz L, Cosa R, Blanco L et al (2007) Curative laparoscopic resection for pancreatic neoplasms: a critical analysis from a single institution. J Gastrointest Surg 11:1607–1621 (discussion 1621–2)CrossRefPubMed Fernández-Cruz L, Cosa R, Blanco L et al (2007) Curative laparoscopic resection for pancreatic neoplasms: a critical analysis from a single institution. J Gastrointest Surg 11:1607–1621 (discussion 1621–2)CrossRefPubMed
15.
Zurück zum Zitat Gagner M, Pomp A (1994) Laparoscopic pylorus-preserving pancreatoduodenectomy. Surg Endosc 8:408–410CrossRefPubMed Gagner M, Pomp A (1994) Laparoscopic pylorus-preserving pancreatoduodenectomy. Surg Endosc 8:408–410CrossRefPubMed
16.
Zurück zum Zitat Girgis MD, Zenati MS, Steve J et al (2017) Robotic approach mitigates perioperative morbidity in obese patients following pancreaticoduodenectomy. HPB (Oxford) 19:93–98CrossRef Girgis MD, Zenati MS, Steve J et al (2017) Robotic approach mitigates perioperative morbidity in obese patients following pancreaticoduodenectomy. HPB (Oxford) 19:93–98CrossRef
17.
Zurück zum Zitat Giulianotti PC, Sbrana F, Bianco FM et al (2010) Robot-assisted laparoscopic pancreatic surgery: single-surgeon experience. Surg Endosc 24:1646–1657CrossRefPubMed Giulianotti PC, Sbrana F, Bianco FM et al (2010) Robot-assisted laparoscopic pancreatic surgery: single-surgeon experience. Surg Endosc 24:1646–1657CrossRefPubMed
18.
Zurück zum Zitat Hackert T, Hinz U, Fritz S et al (2011) Enucleation in pancreatic surgery: indications, technique, and outcome compared to standard pancreatic resections. Langenbecks Arch Surg 396:1197–1203CrossRefPubMed Hackert T, Hinz U, Fritz S et al (2011) Enucleation in pancreatic surgery: indications, technique, and outcome compared to standard pancreatic resections. Langenbecks Arch Surg 396:1197–1203CrossRefPubMed
19.
Zurück zum Zitat Jin JB, Qin K, Li H et al (2016) Robotic enucleation for benign or borderline tumours of the pancreas: a retrospective analysis and comparison from a high-volume centre in asia. World J Surg 40:3009–3020CrossRefPubMed Jin JB, Qin K, Li H et al (2016) Robotic enucleation for benign or borderline tumours of the pancreas: a retrospective analysis and comparison from a high-volume centre in asia. World J Surg 40:3009–3020CrossRefPubMed
20.
Zurück zum Zitat Jin T, Altaf K, Xiong JJ et al (2012) A systematic review and meta-analysis of studies comparing laparoscopic and open distal pancreatectomy. HPB (Oxford) 14:711–724CrossRef Jin T, Altaf K, Xiong JJ et al (2012) A systematic review and meta-analysis of studies comparing laparoscopic and open distal pancreatectomy. HPB (Oxford) 14:711–724CrossRef
21.
Zurück zum Zitat Kang CM, Kim DH, Lee WJ et al (2011) Conventional laparoscopic and robot-assisted spleen-preserving pancreatectomy: does da Vinci have clinical advantages? Surg Endosc 25:2004–2009CrossRefPubMed Kang CM, Kim DH, Lee WJ et al (2011) Conventional laparoscopic and robot-assisted spleen-preserving pancreatectomy: does da Vinci have clinical advantages? Surg Endosc 25:2004–2009CrossRefPubMed
22.
Zurück zum Zitat Kneuertz PJ, Patel SH, Chu CK et al (2012) Laparoscopic distal pancreatectomy: trends and lessons learned through an 11-year experience. J Am Coll Surg 215:167–176CrossRefPubMed Kneuertz PJ, Patel SH, Chu CK et al (2012) Laparoscopic distal pancreatectomy: trends and lessons learned through an 11-year experience. J Am Coll Surg 215:167–176CrossRefPubMed
23.
Zurück zum Zitat Kooby DA, Hawkins WG, Schmidt CM et al (2010) A multicenter analysis of distal pancreatectomy for adenocarcinoma: is laparoscopic resection appropriate? J Am Coll Surg 210(779–85):786–787 Kooby DA, Hawkins WG, Schmidt CM et al (2010) A multicenter analysis of distal pancreatectomy for adenocarcinoma: is laparoscopic resection appropriate? J Am Coll Surg 210(779–85):786–787
24.
Zurück zum Zitat Lee SY, Allen PJ, Sadot E, D’Angelica MI, DeMatteo RP, Fong Y, Jarnagin WR, Kingham TP (2015) Distal pancreatectomy: a single institution’s experience in open, laparoscopic, and robotic approaches. J Am Coll Surg 220(1):18–27 Lee SY, Allen PJ, Sadot E, D’Angelica MI, DeMatteo RP, Fong Y, Jarnagin WR, Kingham TP (2015) Distal pancreatectomy: a single institution’s experience in open, laparoscopic, and robotic approaches. J Am Coll Surg 220(1):18–27
25.
Zurück zum Zitat Magge D, Gooding W, Choudry H, Steve J, Steel J, Zureikat A, Krasinskas A, Daouadi M, Lee KK, Hughes SJ, Zeh HJ 3rd, Moser AJ (2013) Comparative effectiveness of minimally invasive and open distal pancreatectomy for ductal adenocarcinoma. JAMA Surg 148(6):525–531 Magge D, Gooding W, Choudry H, Steve J, Steel J, Zureikat A, Krasinskas A, Daouadi M, Lee KK, Hughes SJ, Zeh HJ 3rd, Moser AJ (2013) Comparative effectiveness of minimally invasive and open distal pancreatectomy for ductal adenocarcinoma. JAMA Surg 148(6):525–531
26.
Zurück zum Zitat Melotti G, Butturini G, Piccoli M et al (2007) Laparoscopic distal pancreatectomy: results on a consecutive series of 58 patients. Ann Surg 246:77–82CrossRefPubMedPubMedCentral Melotti G, Butturini G, Piccoli M et al (2007) Laparoscopic distal pancreatectomy: results on a consecutive series of 58 patients. Ann Surg 246:77–82CrossRefPubMedPubMedCentral
27.
Zurück zum Zitat Mesleh MG, Stauffer JA, Bowers SP et al (2013) Cost analysis of open and laparoscopic pancreaticoduodenectomy: a single institution comparison. Surg Endosc 27:4518–4523CrossRefPubMed Mesleh MG, Stauffer JA, Bowers SP et al (2013) Cost analysis of open and laparoscopic pancreaticoduodenectomy: a single institution comparison. Surg Endosc 27:4518–4523CrossRefPubMed
28.
Zurück zum Zitat Müssle B, Distler M, Weitz J et al (2017) Robot-assisted pancreatic resection. Chirurg 88:490–495CrossRefPubMed Müssle B, Distler M, Weitz J et al (2017) Robot-assisted pancreatic resection. Chirurg 88:490–495CrossRefPubMed
29.
Zurück zum Zitat Ohtsuka T, Takahata S, Takanami H et al (2014) Laparoscopic surgery is applicable for larger mucinous cystic neoplasms of the pancreas. J Hepatobiliary Pancreat Sci 21:343–348CrossRefPubMed Ohtsuka T, Takahata S, Takanami H et al (2014) Laparoscopic surgery is applicable for larger mucinous cystic neoplasms of the pancreas. J Hepatobiliary Pancreat Sci 21:343–348CrossRefPubMed
30.
Zurück zum Zitat de Rooij T, Klompmaker S, Abu Hilal M et al (2016) Laparoscopic pancreatic surgery for benign and malignant disease. Nat Rev Gastroenterol Hepatol 13:227–238CrossRefPubMed de Rooij T, Klompmaker S, Abu Hilal M et al (2016) Laparoscopic pancreatic surgery for benign and malignant disease. Nat Rev Gastroenterol Hepatol 13:227–238CrossRefPubMed
31.
Zurück zum Zitat de Rooij T, van Hilst J, Boerma D et al (2016) Impact of a nationwide training program in minimally invasive distal pancreatectomy (LAELAPS). Ann Surg 264:754–762CrossRefPubMed de Rooij T, van Hilst J, Boerma D et al (2016) Impact of a nationwide training program in minimally invasive distal pancreatectomy (LAELAPS). Ann Surg 264:754–762CrossRefPubMed
32.
Zurück zum Zitat de Rooij T, van Hilst J, Vogel JA et al (2017) Minimally invasive versus open distal pancreatectomy (LEOPARD): study protocol for a randomized controlled trial. Trials 18:166CrossRefPubMedPubMedCentral de Rooij T, van Hilst J, Vogel JA et al (2017) Minimally invasive versus open distal pancreatectomy (LEOPARD): study protocol for a randomized controlled trial. Trials 18:166CrossRefPubMedPubMedCentral
33.
Zurück zum Zitat de Rooij T, Jilesen AP, Boerma D, Bonsing BA, Bosscha K, van Dam RM, van Dieren S, Dijkgraaf MG, van Eijck CH, Gerhards MF, van Goor H, van der Harst E, de Hingh IH, Kazemier G, Klaase JM, Molenaar IQ, Nieveen van Dijkum EJ, Patijn GA, van Santvoort HC, Scheepers JJ, van der Schelling GP, Sieders E, Vogel JA, Busch OR, Besselink MG; Dutch Pancreatic Cancer Group (2015) A nationwide comparison of laparoscopic and open distal pancreatectomy for benign and malignant disease. J Am Coll Surg 220(3):263–270.e1 de Rooij T, Jilesen AP, Boerma D, Bonsing BA, Bosscha K, van Dam RM, van Dieren S, Dijkgraaf MG, van Eijck CH, Gerhards MF, van Goor H, van der Harst E, de Hingh IH, Kazemier G, Klaase JM, Molenaar IQ, Nieveen van Dijkum EJ, Patijn GA, van Santvoort HC, Scheepers JJ, van der Schelling GP, Sieders E, Vogel JA, Busch OR, Besselink MG; Dutch Pancreatic Cancer Group (2015) A nationwide comparison of laparoscopic and open distal pancreatectomy for benign and malignant disease. J Am Coll Surg 220(3):263–270.e1
34.
Zurück zum Zitat Schwarz L, Fleming J, Katz M et al (2016) Total laparoscopic central pancreatectomy with pancreaticogastrostomy for high-risk cystic neoplasm. Ann Surg Oncol 23:1035CrossRefPubMed Schwarz L, Fleming J, Katz M et al (2016) Total laparoscopic central pancreatectomy with pancreaticogastrostomy for high-risk cystic neoplasm. Ann Surg Oncol 23:1035CrossRefPubMed
35.
Zurück zum Zitat Shakir M, Boone BA, Polanco PM et al (2015) The learning curve for robotic distal pancreatectomy: an analysis of outcomes of the first 100 consecutive cases at a high-volume pancreatic centre. HPB (Oxford) 17:580–586CrossRef Shakir M, Boone BA, Polanco PM et al (2015) The learning curve for robotic distal pancreatectomy: an analysis of outcomes of the first 100 consecutive cases at a high-volume pancreatic centre. HPB (Oxford) 17:580–586CrossRef
36.
Zurück zum Zitat Shin SH, Kim SC, Song KB, Hwang DW, Lee JH, Lee D, Lee JW, Jun E, Park KM, Lee YJ (2015) A comparative study of laparoscopic vs. open distal pancreatectomy for left-sided ductal adenocarcinoma: a propensity score-matched analysis. J Am Coll Surg 220(2):177–185 Shin SH, Kim SC, Song KB, Hwang DW, Lee JH, Lee D, Lee JW, Jun E, Park KM, Lee YJ (2015) A comparative study of laparoscopic vs. open distal pancreatectomy for left-sided ductal adenocarcinoma: a propensity score-matched analysis. J Am Coll Surg 220(2):177–185
37.
Zurück zum Zitat Siech M, Bartsch D, Beger HG et al (2012) Indications for laparoscopic pancreas operations: results of a consensus conference and the previous laparoscopic pancreas register. Chirurg 83:247–253CrossRefPubMed Siech M, Bartsch D, Beger HG et al (2012) Indications for laparoscopic pancreas operations: results of a consensus conference and the previous laparoscopic pancreas register. Chirurg 83:247–253CrossRefPubMed
38.
Zurück zum Zitat Siech M, Strauss P, Huschitt S et al (2017) The indications for Laparoscopic Pancreatectomy. Dtsch Arztebl Int 114:263–268PubMedPubMedCentral Siech M, Strauss P, Huschitt S et al (2017) The indications for Laparoscopic Pancreatectomy. Dtsch Arztebl Int 114:263–268PubMedPubMedCentral
39.
Zurück zum Zitat Song KB, Kim SC, Hwang DW et al (2015) Enucleation for benign or low-grade malignant lesions of the pancreas: single-center experience with 65 consecutive patients. Surgery 158:1203–1210CrossRefPubMed Song KB, Kim SC, Hwang DW et al (2015) Enucleation for benign or low-grade malignant lesions of the pancreas: single-center experience with 65 consecutive patients. Surgery 158:1203–1210CrossRefPubMed
40.
Zurück zum Zitat Stauffer JA, Rosales-Velderrain A, Goldberg RF et al (2013) Comparison of open with laparoscopic distal pancreatectomy: a single institution’s transition over a 7-year period. HPB (Oxford) 15:149–155CrossRef Stauffer JA, Rosales-Velderrain A, Goldberg RF et al (2013) Comparison of open with laparoscopic distal pancreatectomy: a single institution’s transition over a 7-year period. HPB (Oxford) 15:149–155CrossRef
41.
Zurück zum Zitat Stewart CL, Meguid C, Chapman B et al (2016) Evolving trends towards minimally invasive surgery for solid-pseudopapillary neoplasms. Ann Surg Oncol 23:4165–4168CrossRefPubMed Stewart CL, Meguid C, Chapman B et al (2016) Evolving trends towards minimally invasive surgery for solid-pseudopapillary neoplasms. Ann Surg Oncol 23:4165–4168CrossRefPubMed
42.
Zurück zum Zitat Strobel O, Cherrez A, Hinz U et al (2015) Risk of pancreatic fistula after enucleation of pancreatic tumours. Br J Surg 102:1258–1266CrossRefPubMed Strobel O, Cherrez A, Hinz U et al (2015) Risk of pancreatic fistula after enucleation of pancreatic tumours. Br J Surg 102:1258–1266CrossRefPubMed
43.
Zurück zum Zitat Tian F, Hong XF, Wu WM et al (2016) Propensity score-matched analysis of robotic versus open surgical enucleation for small pancreatic neuroendocrine tumours. Br J Surg 103:1358–1364CrossRefPubMed Tian F, Hong XF, Wu WM et al (2016) Propensity score-matched analysis of robotic versus open surgical enucleation for small pancreatic neuroendocrine tumours. Br J Surg 103:1358–1364CrossRefPubMed
44.
Zurück zum Zitat Tol JA, Gouma DJ, Bassi C et al (2014) Definition of a standard lymphadenectomy in surgery for pancreatic ductal adenocarcinoma: a consensus statement by the International Study Group on Pancreatic Surgery (ISGPS). Surgery 156:591–600CrossRefPubMed Tol JA, Gouma DJ, Bassi C et al (2014) Definition of a standard lymphadenectomy in surgery for pancreatic ductal adenocarcinoma: a consensus statement by the International Study Group on Pancreatic Surgery (ISGPS). Surgery 156:591–600CrossRefPubMed
45.
Zurück zum Zitat Venkat R, Edil BH, Schulick RD et al (2012) Laparoscopic distal pancreatectomy is associated with significantly less overall morbidity compared to the open technique: a systematic review and meta-analysis. Ann Surg 255:1048–1059CrossRefPubMed Venkat R, Edil BH, Schulick RD et al (2012) Laparoscopic distal pancreatectomy is associated with significantly less overall morbidity compared to the open technique: a systematic review and meta-analysis. Ann Surg 255:1048–1059CrossRefPubMed
46.
Zurück zum Zitat Wolk S, Distler M, Kersting S et al (2015) Evaluation of central pancreatectomy and pancreatic enucleation as pancreatic resections – a comparison. Int J Surg 22:118–124CrossRefPubMed Wolk S, Distler M, Kersting S et al (2015) Evaluation of central pancreatectomy and pancreatic enucleation as pancreatic resections – a comparison. Int J Surg 22:118–124CrossRefPubMed
48.
Zurück zum Zitat Zhang J, Wu WM, You L et al (2013) Robotic versus open pancreatectomy: a systematic review and meta-analysis. Ann Surg Oncol 20:1774–1780CrossRefPubMed Zhang J, Wu WM, You L et al (2013) Robotic versus open pancreatectomy: a systematic review and meta-analysis. Ann Surg Oncol 20:1774–1780CrossRefPubMed
49.
Zurück zum Zitat Zhang RC, Zhou YC, Mou YP et al (2016) Laparoscopic versus open enucleation for pancreatic neoplasms: clinical outcomes and pancreatic function analysis. Surg Endosc 30:2657–2665CrossRefPubMed Zhang RC, Zhou YC, Mou YP et al (2016) Laparoscopic versus open enucleation for pancreatic neoplasms: clinical outcomes and pancreatic function analysis. Surg Endosc 30:2657–2665CrossRefPubMed
50.
Zurück zum Zitat Zhou JY, Xin C, Mou YP et al (2016) Robotic versus laparoscopic distal pancreatectomy: a meta-analysis of short-term outcomes. PLOS ONE 11:e0151189CrossRefPubMedPubMedCentral Zhou JY, Xin C, Mou YP et al (2016) Robotic versus laparoscopic distal pancreatectomy: a meta-analysis of short-term outcomes. PLOS ONE 11:e0151189CrossRefPubMedPubMedCentral
51.
Zurück zum Zitat Zureikat AH, Moser AJ, Boone BA et al (2013) 250 robotic pancreatic resections: safety and feasibility. Ann Surg 258:554–559 (discussion 559–62)PubMedPubMedCentral Zureikat AH, Moser AJ, Boone BA et al (2013) 250 robotic pancreatic resections: safety and feasibility. Ann Surg 258:554–559 (discussion 559–62)PubMedPubMedCentral
52.
Zurück zum Zitat Zureikat AH, Postlewait LM, Liu Y et al (2016) A multi-institutional comparison of perioperative outcomes of robotic and open pancreaticoduodenectomy. Ann Surg 264:640–649CrossRefPubMed Zureikat AH, Postlewait LM, Liu Y et al (2016) A multi-institutional comparison of perioperative outcomes of robotic and open pancreaticoduodenectomy. Ann Surg 264:640–649CrossRefPubMed
Metadaten
Titel
Minimalinvasive und roboterassistierte Chirurgie bei zystischen Pankreastumoren
verfasst von
Prof. Dr. T. Welsch
M. Distler
J. Weitz
Publikationsdatum
25.08.2017
Verlag
Springer Medizin
Erschienen in
Die Chirurgie / Ausgabe 11/2017
Print ISSN: 2731-6971
Elektronische ISSN: 2731-698X
DOI
https://doi.org/10.1007/s00104-017-0496-y

Weitere Artikel der Ausgabe 11/2017

Die Chirurgie 11/2017 Zur Ausgabe

Update Onkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.