nach oben

Erschienen in:

28.06.2016 | Original Article

Pars cohort study of non-communicable diseases in Iran: protocol and preliminary results

verfasst von: Abdullah Gandomkar, Hossein Poustchi, Maryam Moini, Mohsen Moghadami, Hadi Imanieh, Mohammad Reza Fattahi, Seyyed Mohammad Taghi Ayatollahi, Mohammad Mahdi Sagheb, Amir Anushiravani, Roozbeh Mortazavi, Sadaf Ghajarieh Sepanlou, Reza Malekzadeh

Erschienen in: International Journal of Public Health | Ausgabe 3/2017

Einloggen, um Zugang zu erhalten

Abstract

Objectives

The pars cohort study (PCS) is a 10-year cohort study aiming to investigate the burden and the major risk factors of non-communicable diseases, and to establish a setting to launch interventions for prevention of these diseases and controlling their risk factors.

Methods

All inhabitants of Valashahr district in South of Iran, aged 40–75 years, were invited to undergo interviews and physical examination, and to provide biological samples. A total of 9264 invitees accepted to participate in the study (95 % participation rate) and were recruited from 2012 to 2014. Active follow-up was also carried out after 12 months.

Results

About 46 % of participants were male and 54 % were female. About 14.0 % of the participants were current smokers and 8.4 % were ever opium users. The prevalence of overweight and obesity were 37.3 and 18.2 %, respectively. The prevalence of hypertension was 26.9 %. A total of 49 participants died during a median follow-up of one year.

Conclusions

PCS with its large scale and wealth of socio-economic and medical data can be a unique platform for studying the etiology of non-communicable diseases and effective interventions in Iran.

Abnet CC, Saadatian-Elahi M, Pourshams A et al (2004) Reliability and validity of opiate use self-report in a population at high risk for esophageal cancer in Golestan, Iran. Cancer Epidemiol Biomark Prev Publ Am Assoc Cancer Res Cosponsored Am Soc Prev Oncol 13(6):1068–1070

Azizi F, Rahmani M, Emami H et al (2000) Tehran lipid and glucose study: rationale and design. CVD Prev 3(3):242–247

Bahrami H, Sadatsafavi M, Pourshams A et al (2006) Obesity and hypertension in an Iranian cohort study; Iranian women experience higher rates of obesity and hypertension than American women. BMC Public Health 6:158. doi:10.1186/1471-2458-6-158 CrossRefPubMedPubMedCentral

Etemadi A, Islami F, Phillips DH et al (2013) Variation in PAH-related DNA adduct levels among non-smokers: the role of multiple genetic polymorphisms and nucleotide excision repair phenotype. Int J Cancer J Int du Cancer 132(12):2738–2747. doi:10.1002/ijc.27953 CrossRef

Etemadi A, Abnet CC, Kamangar F et al (2014) Impact of body size and physical activity during adolescence and adult life on overall and cause-specific mortality in a large cohort study from Iran. Eur J Epidemiol 29(2):95–109. doi:10.1007/s10654-014-9883-6 CrossRefPubMed

Fitzmaurice C, Dicker D, Pain A et al (2015) The global burden of cancer 2013. JAMA Oncol 1(4):505–527. doi:10.1001/jamaoncol.2015.0735 CrossRefPubMed

Garg VP, Vedanthan R, Islami F et al (2015) Heart disease is associated with anthropometric indices and change in body size perception over the life course: the golestan cohort study. Global Heart. doi:10.3945/ajcn.115.107847 PubMedPubMedCentral

Gharipour M, Sarrafzadegan N, Sadeghi M et al (2015) The metabolic syndrome and associated lifestyle factors among the Iranian population. Adv Biomed Res 4:84. doi:10.4103/2277-9175.156645 CrossRefPubMedPubMedCentral

Global Burden of Disease (GBD) Collaborators (2015a) Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet 385(9963):117–71 doi:10.1016/s0140-6736(14)61682-2

Global Burden of Disease (GBD) Collaborators (2015b) Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet 386(9995):743–800. doi:10.1016/s0140-6736(15)60692-4 CrossRef

Golozar A, Khademi H, Kamangar F et al (2011) Diabetes mellitus and its correlates in an Iranian adult population. PLoS ONE 6(10):e26725. doi:10.1371/journal.pone.0026725 CrossRefPubMedPubMedCentral

Hashemian M, Poustchi H, Abnet CC et al (2015) Dietary intake of minerals and risk of esophageal squamous cell carcinoma: results from the Golestan Cohort Study. Am J Clin Nutr. doi:10.3945/ajcn.115.107847 PubMedPubMedCentral

Islami F, Kamangar F, Aghcheli K et al (2004) Epidemiologic features of upper gastrointestinal tract cancers in Northeastern Iran. Br J Cancer 90(7):1402–1406. doi:10.1038/sj.bjc.6601737 CrossRefPubMedPubMedCentral

Islami F, Kamangar F, Nasrollahzadeh D et al (2009a) Socio-economic status and oesophageal cancer: results from a population-based case-control study in a high-risk area. Int J Epidemiol 38(4):978–988. doi:10.1093/ije/dyp195 CrossRefPubMedPubMedCentral

Islami F, Malekshah AF, Kimiagar M et al (2009b) Patterns of food and nutrient consumption in northern Iran, a high-risk area for esophageal cancer. Nutr Cancer 61(4):475–483. doi:10.1080/01635580902803735 CrossRefPubMedPubMedCentral

Islami F, Pourshams A, Vedanthan R et al (2013) Smoking water-pipe, chewing nass and prevalence of heart disease: a cross-sectional analysis of baseline data from the Golestan Cohort Study, Iran. Heart (British Cardiac Society) 99(4):272–278. doi:10.1136/heartjnl-2012-302861

Kamangar F, Malekzadeh R, Dawsey SM, Saidi F (2007) Esophageal cancer in Northeastern Iran: a review. Arch Iran Med 10(1):70–82PubMed

Khademi H, Etemadi A, Kamangar F et al (2010) Verbal autopsy: reliability and validity estimates for causes of death in the Golestan Cohort Study in Iran. PLoS ONE 5(6):e11183. doi:10.1371/journal.pone.0011183 CrossRefPubMedPubMedCentral

Khademi H, Malekzadeh R, Pourshams A et al (2012) Opium use and mortality in Golestan Cohort Study: prospective cohort study of 50,000 adults in Iran. BMJ (Clinical Research ed) 344:e2502. doi:10.1136/bmj.e2502

Majed M, Moradmand Badie S (2011) A pilot double-blind randomised placebo-controlled trial of the effects of fixed-dose combination therapy (‘polypill’) on cardiovascular risk factors. Arch Iran Med 14(1):78–80PubMed

Malekshah AF, Kimiagar M, Saadatian-Elahi M et al (2006) Validity and reliability of a new food frequency questionnaire compared to 24 h recalls and biochemical measurements: pilot phase of Golestan cohort study of esophageal cancer. Eur J Clin Nutr 60(8):971–977. doi:10.1038/sj.ejcn.1602407 CrossRefPubMed

Malekzadeh F, Marshall T, Pourshams A et al (2010) A pilot double-blind randomised placebo-controlled trial of the effects of fixed-dose combination therapy (‘polypill’) on cardiovascular risk factors. Int J Clin Pract 64(9):1220–1227. doi:10.1111/j.1742-1241.2010.02412.x CrossRefPubMed

Malekzadeh MM, Etemadi A, Kamangar F et al (2013a) Prevalence, awareness and risk factors of hypertension in a large cohort of Iranian adult population. J Hypertens 31(7):1364–1371. doi:10.1097/HJH.0b013e3283613053 (discussion 1371) CrossRefPubMedPubMedCentral

Malekzadeh MM, Khademi H, Pourshams A et al (2013b) Opium use and risk of mortality from digestive diseases: a prospective cohort study. Am J Gastroenterol 108(11):1757–1765. doi:10.1038/ajg.2013.336 CrossRefPubMed

Murray CJ, Barber RM, Foreman KJ et al (2015) Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990-2013: quantifying the epidemiological transition. Lancet. doi:10.1016/s0140-6736(15)61340-x

Najafi I, Attari F, Islami F et al (2010) Renal function and risk factors of moderate to severe chronic kidney disease in Golestan Province, northeast of Iran. PLoS ONE 5(12):e14216. doi:10.1371/journal.pone.0014216 CrossRefPubMedPubMedCentral

Najafi I, Shakeri R, Islami F et al (2012) Prevalence of chronic kidney disease and its associated risk factors: the first report from Iran using both microalbuminuria and urine sediment. Arch Iran Med 15(2):70–75PubMed

Najafipour H, Mirzazadeh A, Haghdoost A et al (2012) Coronary artery disease risk factors in an Urban and Peri-urban setting, Kerman, Southeastern Iran (KERCADR Study): methodology and preliminary report. Iran J Publ Health 41(9):86–92

Nasrollahzadeh D, Kamangar F, Aghcheli K et al (2008) Opium, tobacco, and alcohol use in relation to oesophageal squamous cell carcinoma in a high-risk area of Iran. Br J Cancer 98(11):1857–1863. doi:10.1038/sj.bjc.6604369 CrossRefPubMedPubMedCentral

Ostovaneh MR, Poustchi H, Hemming K et al (2014) Polypill for the prevention of cardiovascular disease (PolyIran): study design and rationale for a pragmatic cluster randomized controlled trial. Eur J Prev Cardiol. doi:10.1177/2047487314550803 PubMed

Pourshams A, Saadatian-Elahi M, Nouraie M et al (2005) Golestan cohort study of oesophageal cancer: feasibility and first results. Br J Cancer 92(1):176–181. doi:10.1038/sj.bjc.6602249 CrossRefPubMed

Pourshams A, Khademi H, Malekshah AF et al (2010) Cohort profile: the golestan cohort study—a prospective study of oesophageal cancer in northern Iran. Int J Epidemiol 39(1):52–59. doi:10.1093/ije/dyp161 CrossRefPubMed

Rabiei K, Kelishadi R, Sarrafzadegan N et al (2009) Process evaluation of a community-based program for prevention and control of non-communicable disease in a developing country: the Isfahan Healthy Heart Program, Iran. BMC Publ health 9:57. doi:10.1186/1471-2458-9-57 CrossRef

Sepanlou SG, Malekzadeh R, Poustchi H et al (2015a) The clinical performance of an office-based risk scoring system for fatal cardiovascular diseases in North-East of Iran. PLoS ONE 10(5):e0126779. doi:10.1016/j.gheart.2014.10.004 CrossRefPubMedPubMedCentral

Sepanlou SG, Sharafkhah M, Poustchi MM et al (2015b) Hypertension and mortality in the Golestan Cohort Study: a prospective study of 50 000 adults in Iran. J Hum Hypertens. doi:10.1038/jhh.2015.57 PubMed

Shakeri R, Kamangar F, Nasrollahzadeh D et al (2012) Is opium a real risk factor for esophageal cancer or just a methodological artifact? Hospital and neighborhood controls in case-control studies. PLoS ONE 7(3):e32711. doi:10.1371/journal.pone.0032711 CrossRefPubMedPubMedCentral

Shakeri R, Malekzadeh R, Etemadi A et al (2013a) Association of tooth loss and oral hygiene with risk of gastric adenocarcinoma. Cancer Prev Res (Philadelphia, Pa) 6(5):477–482. doi:10.1158/1940-6207.capr-12-0491 CrossRef

Shakeri R, Malekzadeh R, Etemadi A et al (2013b) Opium: an emerging risk factor for gastric adenocarcinoma. Int J Cancer 133(2):455–461. doi:10.1002/ijc.28018 CrossRefPubMed

The WHO STEPwise approach to non-communicable disease risk factor surveillance (STEPS) (2004). World Health Organization, Geneva. Available at: www.who.int/chp/steps [Last accessed 12 April 2016]

Zamani N, Hajifaraji M, Fazel-tabar Malekshah A et al (2013) A case-control study of the relationship between gastric cancer and meat consumption in Iran. Arch Iran Med 16(6):324–329PubMed

Titel: Pars cohort study of non-communicable diseases in Iran: protocol and preliminary results
verfasst von: Abdullah Gandomkar
Hossein Poustchi
Maryam Moini
Mohsen Moghadami
Hadi Imanieh
Mohammad Reza Fattahi
Seyyed Mohammad Taghi Ayatollahi
Mohammad Mahdi Sagheb
Amir Anushiravani
Roozbeh Mortazavi
Sadaf Ghajarieh Sepanlou
Reza Malekzadeh
Publikationsdatum: 28.06.2016
Verlag: Springer International Publishing
Erschienen in: International Journal of Public Health / Ausgabe 3/2017
Print ISSN: 1661-8556
Elektronische ISSN: 1661-8564
DOI: https://doi.org/10.1007/s00038-016-0848-2

Springer Medizin

Abstract

Objectives

Methods

Results

Conclusions

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 3/2017

Premature deaths attributed to ambient air pollutants: let us interpret the Robins–Greenland theorem correctly

A novel method for modelling interaction between categorical variables

Time trends and determinants of multiple development delays in Bavarian preschool children: a retrospective analysis from 1997 to 2010

Gallstone disease and mortality: a cohort study

Participation in organized leisure-time activities and risk behaviors in Czech adolescents

Examining the relationship between human resources and mortality: the effects of methodological choices