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Pediatric Cardiology

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01.10.2007 | CASE REPORT

Parvovirus B19 Infection Associated with Dilated Cardiomyopathy in Patients with Previous Anthracycline Exposure

verfasst von: C. J. McMahon, H. Murchan, T. Prendiville, M. Burch

Erschienen in: Pediatric Cardiology | Ausgabe 5/2007

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Abstract

We describe two children with previous anthracycline exposure for cancer who presented with acute decompensated left ventricular dysfunction. Both patients had evidence of dilated cardiomyopathy and required mechanical ventilation and inotropic support. Parvovirus B19 was detected by polymerase chain reaction of the blood. After several weeks of ventilation and inotropic support, both patients were weaned from ventilation and managed with oral carvedilol, ACE inhibition, and diuretics. Acute left ventricular decompensation in patients following anthracycline exposure may not be solely attributed to drug exposure, and viral etiologies should be considered.

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Titel: Parvovirus B19 Infection Associated with Dilated Cardiomyopathy in Patients with Previous Anthracycline Exposure
verfasst von: C. J. McMahon
H. Murchan
T. Prendiville
M. Burch
Publikationsdatum: 01.10.2007
Verlag: Springer-Verlag
Erschienen in: Pediatric Cardiology / Ausgabe 5/2007
Print ISSN: 0172-0643
Elektronische ISSN: 1432-1971
DOI: https://doi.org/10.1007/s00246-006-0147-4

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