Background
Methods
Ethics approval and consent to participate
Conduit harvest
Primary analysis: assessment of perfect patency (absence of conduit lumen irregularity)
Secondary analysis: assessment of patency (patent even in presence of conduit lumen irregularity)
Statistics
Results
Variable | n (%) |
---|---|
Male | 48 (96) |
Symptoms | 1 (2) |
Current smoker | 2 (4) |
Diabetes | 21 (42) |
Hypertension | 37 (74) |
Hypercholesterolemia | 29 (58) |
Family history of IHD | 1 (2) |
Dialysis | 2 (4) |
Chronic lung disease | 1 (2) |
Atrial fibrillation | 8 (16) |
Coronary stent pre-research angiogram | 1 (2) |
Distribution of anastomoses
IMA n (%) | RA n (%) | SVG n (%) | Total n (%) | |
---|---|---|---|---|
Coronary Territory | ||||
LAD | 57 | 8 | 6 | 71 (36) |
Cx | 4 | 50 | 18 | 72 (37) |
RCA | 1 | 19 | 33 | 53 (27) |
Total | 62 (32) | 77 (39) | 57 (29) | 196 (100) |
Anastomosis | ||||
End-Side | 53 | 67 | 56 | 176 |
Sequential | 9 | 10 | 1 | 20 |
Graft Origin | ||||
Aorta | 6 | 70 | 56 | 132 |
Pedicled | 56 | 0 | 0 | 56 |
Y graft | 0 | 7 | 1 | 8 |
Coronary branch | IMA | RA | SVG | Total |
---|---|---|---|---|
LAD | 46 | 1 | 1 | 48 |
D1 | 10 | 5 | 5 | 20 |
D2 | 1 | 2 | 0 | 3 |
Intermediate | 1 | 5 | 3 | 9 |
M1 | 2 | 21 | 9 | 32 |
M2 | 0 | 19 | 5 | 24 |
M3 | 1 | 5 | 1 | 7 |
RCA | 0 | 1 | 1 | 2 |
PDA | 1 | 14 | 26 | 41 |
LVBr | 0 | 4 | 6 | 10 |
Total | 62 | 77 | 57 | 196 |
Comparison | Perfect Patency n (%) | P (GLMM) | Patency n (%) | P (GLMM) |
---|---|---|---|---|
LAD, CX, RCA | 0.997 | 0.289 | ||
LAD Cx | 63/71 (88.7) 53/72 (73.6) | 0.940 | 66/71 (93.0) 67/72 (93.1) | 0.277 |
LAD RCA | 63/71 (88.7) 25/53 (47.2) | 0.941 | 66/71 (93.0) 46/53 (86.8) | 0.901 |
Cx RCA | 53/72 (73.6) 25/53 (47.2) | 0.997 | 67/72 (93.1) 46/53 (86.8) | 0.136 |
Global predictors
Conduit analysis
Comparison | Perfect patency n (%) | P (GLMM) | Patency n (%) | P (GLMM) |
---|---|---|---|---|
IMA, RA, SVG | < 0.001 | 0.049 | ||
IMA vs. RA | 60/62 (96.8) 71/77 (92.2) | 0.309 | 60/62 (96.8) 72/77 (93.5) | 0.169 |
IMA vs. SVG | 60/62 (96.8) 10/57 (17.5) | < 0.001 | 60/62 (96.8) 47/57 (82.5) | 0.021 |
RA vs. SVG | 71/77 (92.2) 10/57 (17.5) | < 0.001 | 72/77 (93.5) 47/57 (82.5) | 0.175 |
Arterial, SVG | < 0.001 | 0.037 | ||
Arterial vs. SVG | 131/139 (94.2) 10/57 (17.5) | < 0.001 | 132/139 (95.0) 47/57 (82.5) | 0.037 |
Effect of preoperative coronary artery stenosis
Variable | Perfect patency P (GLMM) | Patency P (GLMM) |
---|---|---|
IMA, RA, SVG | 0.317 | < 0.001 |
IMA | 0.204 | 0.133 |
RA | 0.030 | 0.007 |
SVG | 0.275 | 0.032 |
Variable | Patent + normal all 3 conduits (n = 6) | Other (n = 43) | P value |
---|---|---|---|
Age | 58.8 ± 9 | 61.2 ± 7.2 | 0.455 |
Gender | 6 (100) | 41 (95.3) | 1 |
Preoperative factors | |||
Current Smoker | 0 | 2 (4.7) | 1 |
Diabetes | 4 (66.7) | 16 (37.2) | 0.21 |
Hypertension | 5 (83.3) | 31 (72.1) | 1 |
Family History | 0 | 1 (2.4) | 1 |
Cholesterol | 4 (66.7) | 24 (55.8) | 0.688 |
Dialysis | 0 | 1 (2.3) | 1 |
COPD | 0 | 3 (7) | 1 |
AF | 1 (16.7) | 6 (14) | 1 |
Postoperative factors | |||
Angina | 0 | 1 (2.3) | 1 |
Myocardial Infarction | 0 | 0 | |
PCI | 0 | 2 (4.7) | 1 |
Redo CAGS | 0 | 0 |