Skip to main content
Erschienen in: Abdominal Radiology 2/2019

25.08.2018 | Pictorial essay

Pathological variants of hepatocellular carcinoma on MRI: emphasis on histopathologic correlation

verfasst von: Hsien Min Low, Jin Young Choi, Cher Heng Tan

Erschienen in: Abdominal Radiology | Ausgabe 2/2019

Einloggen, um Zugang zu erhalten

Abstract

Hepatocellular carcinoma (HCC) is a unique tumor because it is one of the few cancers which can be treated based on imaging alone. Magnetic resonance imaging (MRI) carries higher sensitivity and specificity for the diagnosis of HCC than either computed tomography (CT) or ultrasound. MRI is imaging modality of choice for the evaluation of complex liver lesions and HCC because of its inherent ability to depict cellularity, fat, and hepatocyte composition with high soft tissue contrast. The imaging features of progressed HCC are well described. However, many HCC tumors do not demonstrate classical imaging features, posing a diagnostic dilemma to radiologists. Some of these can be attributed to variations in tumor biology and histology, which result in radiological features that differ from the typical progressed HCC. This pictorial review seeks to demonstrate the appearance of different variants of HCC on MRI imaging, in relation to their histopathologic features.
Literatur
3.
Zurück zum Zitat Tan CH, Thng CH, Low AS, et al. (2011) Wash-out of hepatocellular carcinoma: quantitative region of interest analysis on CT. Ann Acad Med Singapore 40(6):269–275PubMed Tan CH, Thng CH, Low AS, et al. (2011) Wash-out of hepatocellular carcinoma: quantitative region of interest analysis on CT. Ann Acad Med Singapore 40(6):269–275PubMed
8.
Zurück zum Zitat American College of Radiology (2014) Liver Imaging and Reporting System version 2014. Accessed 1 May 2017 American College of Radiology (2014) Liver Imaging and Reporting System version 2014. Accessed 1 May 2017
18.
19.
20.
Zurück zum Zitat Libbrecht L, Craninx M, Nevens F, Desmet V, Roskams T (2001) Predictive value of liver cell dysplasia for development of hepatocellular carcinoma in patients with non-cirrhotic and cirrhotic chronic viral hepatitis. Histopathology 39(1):66–73PubMedCrossRef Libbrecht L, Craninx M, Nevens F, Desmet V, Roskams T (2001) Predictive value of liver cell dysplasia for development of hepatocellular carcinoma in patients with non-cirrhotic and cirrhotic chronic viral hepatitis. Histopathology 39(1):66–73PubMedCrossRef
23.
Zurück zum Zitat Monzawa S, Omata K, Shimazu N, et al. (1999) Well-differentiated hepatocellular carcinoma: findings of US, CT, and MR imaging. Abdom Imaging 24(4):392–397PubMedCrossRef Monzawa S, Omata K, Shimazu N, et al. (1999) Well-differentiated hepatocellular carcinoma: findings of US, CT, and MR imaging. Abdom Imaging 24(4):392–397PubMedCrossRef
56.
Zurück zum Zitat Wong VS, Adab N, Youngs GR, Sturgess R (1999) Hepatic sarcoidosis complicated by hepatocellular carcinoma. Eur J Gastroenterol Hepatol 11(3):353–355PubMedCrossRef Wong VS, Adab N, Youngs GR, Sturgess R (1999) Hepatic sarcoidosis complicated by hepatocellular carcinoma. Eur J Gastroenterol Hepatol 11(3):353–355PubMedCrossRef
59.
Zurück zum Zitat Romer FK, Hommelgaard P, Schou G (1998) Sarcoidosis and cancer revisited: a long-term follow-up study of 555 Danish sarcoidosis patients. Eur Respir J 12(4):906–912PubMedCrossRef Romer FK, Hommelgaard P, Schou G (1998) Sarcoidosis and cancer revisited: a long-term follow-up study of 555 Danish sarcoidosis patients. Eur Respir J 12(4):906–912PubMedCrossRef
60.
64.
70.
Zurück zum Zitat Maeda T, Adachi E, Kajiyama K, et al. (1996) Spindle cell hepatocellular carcinoma. A clinicopathologic and immunohistochemical analysis of 15 cases. Cancer 77(1):51–57. 10.1002/(SICI)1097-0142(19960101)77:1<51::AID-CNCR10>3.0.CO;2-7PubMedCrossRef Maeda T, Adachi E, Kajiyama K, et al. (1996) Spindle cell hepatocellular carcinoma. A clinicopathologic and immunohistochemical analysis of 15 cases. Cancer 77(1):51–57. 10.1002/(SICI)1097-0142(19960101)77:1<51::AID-CNCR10>3.0.CO;2-7PubMedCrossRef
71.
Zurück zum Zitat Honda H, Hayashi T, Yoshida K, et al. (1996) Hepatocellular carcinoma with sarcomatous change: characteristic findings of two-phased incremental CT. Abdom Imaging 21(1):37–40PubMedCrossRef Honda H, Hayashi T, Yoshida K, et al. (1996) Hepatocellular carcinoma with sarcomatous change: characteristic findings of two-phased incremental CT. Abdom Imaging 21(1):37–40PubMedCrossRef
Metadaten
Titel
Pathological variants of hepatocellular carcinoma on MRI: emphasis on histopathologic correlation
verfasst von
Hsien Min Low
Jin Young Choi
Cher Heng Tan
Publikationsdatum
25.08.2018
Verlag
Springer US
Erschienen in
Abdominal Radiology / Ausgabe 2/2019
Print ISSN: 2366-004X
Elektronische ISSN: 2366-0058
DOI
https://doi.org/10.1007/s00261-018-1749-z

Weitere Artikel der Ausgabe 2/2019

Abdominal Radiology 2/2019 Zur Ausgabe

Classics in Abdominal Radiology

The “two-tone” testis

Update Radiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.