Ausgabe 2/2020
Inhalt (93 Artikel)
Current Status and Perspective Biomarkers in AFP Negative HCC: Towards Screening for and Diagnosing Hepatocellular Carcinoma at an Earlier Stage
Ping Luo, Sanyun Wu, Yalan Yu, Xinliang Ming, Shuo Li, Xuelan Zuo, Jiancheng Tu
The Association of Androgen Receptor Expression with Renal Cell Carcinoma Risk: a Systematic Review and Meta-Analysis
Peng Yuan, Yue Ge, Xiao Liu, Shen Wang, Zhangqun Ye, Hua Xu, Zhiqiang Chen
Aquaporins 1, 3 and 5 in Different Tumors, their Expression, Prognosis Value and Role as New Therapeutic Targets
Mahdieh-Sadat Moosavi, Yalda Elham
KIBRA Team Up with Partners to Promote Breast Cancer Metastasis
Garima Singh, Sarthak Mishra, Harish Chander
The Small Bowel Cancer Incidence Enigma
Paulo Assumpção, André Khayat, Taíssa Araújo, Williams Barra, Geraldo Ishak, Aline Cruz, Sidney Santos, Ândrea Santos, Samia Demachki, Paula Assumpção, Danielle Calcagno, Ney Santos, Mônica Assumpção, Fabiano Moreira, André Santos, Carolina Assumpção, Gregory Riggins, Rommel Burbano
Solid-pseudopapillary Neoplasms of the Pancreas is still an Enigma: a Clinicopathological Review
Attila Zalatnai, Viktória Kis-Orha
Grading Ductal Carcinoma In Situ (DCIS) of the Breast – What’s Wrong with It?
Gábor Cserni, Anita Sejben
Selective Inhibition of HIF1α Expression by ZnSO4 Has Antitumoral Effects in Human Melanoma
Z. Burián, A. Ladányi, T. Barbai, V. Piurkó, T. Garay, E. Rásó, József Tímár
An Association and Meta-Analysis of Esophageal Squamous Cell Carcinoma Risk Associated with PLCE1 rs2274223, C20orf54 rs13042395 and RUNX1 rs2014300 Polymorphisms
Ziba Nariman-saleh-fam, Zahra Saadatian, Lida Nariman-Saleh-Fam, Elaheh Ouladsahebmadarek, Javad Tavakkoly-Bazzaz, Milad Bastami
Bioinformatics Analysis Makes Revelation to Potential Properties on Regulation and Functions of Human Sox2
Jianguo Zhang, Jianzhong Zhang, Wenqi Chen, Huiyu Li, Meiying Li, Lisha Li
miR-370 Sensitizes TMZ Response Dependent of MGMT Status in Primary Central Nervous System Lymphoma
Xinwei Li, Xueying Xu, Keng Chen, Haijian Wu, Yirong Wang, Shuxu Yang, Kun Wang
BRCA1 and BRCA2 Germline Mutation Analysis in Hereditary Breast/Ovarian Cancer Families from the Aures Region (Eastern Algeria): First Report
Chiraz Mehemmai, Farid Cherbal, Yosr Hamdi, Abdelmoumene Guedioura, Wassila Benbrahim, Rabah Bakour, Sonia Abdelhak
Inhibitory Effect of (2R)-1-(1-Benzofuran-2-yl)-N-propylpentan-2-amine on Lung Adenocarcinoma
Zsolt Mervai, Andrea Reszegi, Ildikó Miklya, József Knoll, Zsuzsa Schaff, Ilona Kovalszky, Kornélia Baghy
Immunohistochemical Study of PD-1/PD-L1 Axis Expression in Oral Tongue Squamous Cell Carcinomas: Effect of Neoadjuvant Chemotherapy on Local Recurrence
Tomofumi Naruse, Souichi Yanamoto, Kohei Okuyama, Keisuke Ohmori, Hiroki Tsuchihashi, Kohei Furukawa, Shin-ichi Yamada, Masahiro Umeda
Association of SLC28A3 Gene Expression and CYP2B6*6 Allele with the Response to Fludarabine Plus Cyclophosphamide in Chronic Lymphocytic Leukemia Patients
Vojin Vukovic, Teodora Karan-Djurasevic, Darko Antic, Natasa Tosic, Tatjana Kostic, Irena Marjanovic, Marija Dencic-Fekete, Vladislava Djurasinovic, Sonja Pavlovic, Biljana Mihaljevic
Effects of microRNA-195 on the Prognosis of Glioma Patients and the Proliferation and Apoptosis of Human Glioma Cells
Ying Jia, Ye Tian, Shuo An, Dong Yang
The Development and Application of Virtual Reality Animation Simulation Technology: Take Gastroscopy Simulation System as an Example
Qianru Wang, Chunjiao Li, Zhongli Xie, Zhiguo Bu, Liwei Shi, Chuan Wang, Feng Jiang
The Haphazard Pattern in Grade-3 Endometrioid Carcinoma Is Associated with Poor Prognosis and Tumor Lymphocyte Infiltration
Morikazu Miyamoto, Masashi Takano, Hitoshi Tsuda, Hiroko Matsuura, Takahiro Sakamoto, Kazuki Takasaki, Kento Kato, Hiroaki Soyama, Tadashi Aoyama, Hiroki Ishibashi, Hideki Iwahashi, Kenichi Furuya
Diagnostic Power of Cytokine M-CSF, Metalloproteinase 2 (MMP-2) and Tissue Inhibitor-2 (TIMP-2) in Cervical Cancer Patients Based on ROC Analysis
Emilia Lubowicka, Monika Zbucka-Kretowska, Iwona Sidorkiewicz, Monika Zajkowska, Ewa Gacuta, Andrzej Puchnarewicz, Lech Chrostek, Maciej Szmitkowski, Sławomir Ławicki
Silencing NID2 by DNA Hypermethylation Promotes Lung Cancer
Jianfeng Wang, Yan Zhao, Hongyan Xu, Jun Ma, Feihai Liang, Qingxu Zou, Fengwu Lin
Syndecan-1 in Liver Diseases
Eszter Regős, Katalin Karászi, Andrea Reszegi, András Kiss, Zsuzsa Schaff, Kornélia Baghy, Ilona Kovalszky
Preliminary Study on Selected Markers of Oxidative Stress, Inflammation and Angiogenesis in Patients with Bladder Cancer
Ewa Sawicka, Ewa Maria Kratz, Beata Szymańska, Anna Guzik, Artur Wesołowski, Paweł Kowal, Lilla Pawlik-Sobecka, Agnieszka Piwowar
Relative and Absolute Expression Analysis of MicroRNAs Associated with Luminal A Breast Cancer– A Comparison
Vahid Arabkari, Eoin Clancy, Róisín M. Dwyer, Michael J. Kerin, Olga Kalinina, Emma Holian, John Newell, Terry J. Smith
Real-World Data of the Correlation between EGFR Determination by Liquid Biopsy in Non-squamous Non-small Cell Lung Cancer (NSCLC) and the EGFR Profile in Tumor Biopsy
Teresa Soria-Comes, Vicente Palomar-Abril, María Martín Ureste, Mónica Tallón Guerola, Inmaculada Concepción Maestu Maiques
Overexpression of Pyruvate Kinase M2 in Tumor Tissues Is Associated with Poor Prognosis in Patients with Hepatocellular Carcinoma
Rui Zhao, Lei Li, Jinbo Yang, Qinfeng Niu, Han Wang, Xiaodong Qin, Ning Zhu, Anchen Shi
TRIM72 Immunohistochemical Expression Can Predict Relapse in Colorectal Carcinoma
M. J. Fernández-Aceñero, M. Cruz, J. Sastre-Varela, J. I. Casal, M. A. Cerón Nieto, L. del Puerto-Nevado, J. García-Foncillas, A. Cebrián
YAP1 Is Involved in Tumorigenic Properties of Prostate Cancer Cells
Filiz Kisaayak Collak, Ummuhan Demir, Fatma Sagir
microRNA-138-5p as a Worse Prognosis Biomarker in Pediatric, Adolescent, and Young Adult Osteosarcoma
Gabriela Molinari Roberto, Regia Caroline Lira, Lara Elis Delsin, Gabriela Maciel Vieira, Marcela Oliveira Silva, Rodrigo Guedes Hakime, Mauricio Eiji Yamashita, Edgard Eduard Engel, Carlos Alberto Scrideli, Luiz Gonzaga Tone, María Sol Brassesco
Immunohistochemical Staining in the Assessment of Melanoma Tumor Thickness
Kambiz Kamyab-Hesary, Alireza Ghanadan, Kamran Balighi, Seyede Faeze Mousavinia, Maryam Nasimi
ACTN4 Promotes the Proliferation, Migration, Metastasis of Osteosarcoma and Enhances its Invasive Ability through the NF-κB Pathway
Qingshan Huang, Xiaodong Li, Zhen Huang, Fengqiang Yu, Xinwen Wang, Shenglin Wang, Zhizhen He, Jianhua Lin
Acute and Late Toxicity after Moderate Hypofractionation with Simultaneous Integrated Boost (SIB) Radiation Therapy for Prostate Cancer. A Single Institution, Prospective Study
Kliton Jorgo, Csaba Polgar, Tibor Major, Gabor Stelczer, Andras Herein, Tamas Pocza, Laszlo Gesztesi, Peter Agoston
Anti-Estrogenic and Anti-Cell Proliferative Effect of Allyl Isothiocyanate in Chemoprevention of Chemically Induced Mammary Carcinogenesis in Rats
Rajakumar Thangarasu, Pugalendhi Pachaiappan, Thilagavathi Subbaiyan
Molecular Profile and Clinicopathologic Features of Follicular Variant Papillary Thyroid Carcinoma
Seo Young Sohn, Jeong-Ju Lee, Jae Hyuk Lee
Attenuation of MAMLD1 Expression Suppresses the Growth and Migratory Properties of Gonadotroph Pituitary Adenomas
Junhui Qi, Wei Ni
Sevoflurane Inhibits Glioma Cells Proliferation and Metastasis through miRNA-124-3p/ROCK1 Axis
Cao Gao, Jiang Shen, Zhi-Xiu Meng, Xiao-Feng He
Irinotecan-Induced Mucositis Is Associated with Goblet Cell Dysregulation and Neural Cell Damage in a Tumour Bearing DA Rat Model
Daniel Thorpe, Ross Butler, Masooma Sultani, Barbara Vanhoecke, Andrea Stringer
Identification and Verification of Two Novel Differentially Expressed Proteins from Non-neoplastic Mucosa and Colorectal Carcinoma Via iTRAQ Combined with Liquid Chromatography-Mass Spectrometry
Yuru Bai, Jiabao Wang, Zhihua Gao, Erqing Dai
Phloretin Inhibits the Human Prostate Cancer Cells Through the Generation of Reactive Oxygen Species
Ukjin Kim, C-Yoon Kim, Ji Min Lee, Hanseul Oh, Bokyeong Ryu, Jin Kim, Jae-Hak Park
The Investigation of Lipoxygenases as Therapeutic Targets in Malignant Pleural Mesothelioma
Lily Oguh-Olayinka, Vijay Agarwal, Dulani Ranatunge, Anne Campbell, Stefan Laufer, Lynn Cawkwell, Michael J. Lind
Dynamic FDG-PET/CT in the Initial Staging of Primary Breast Cancer: Clinicopathological Correlations
Kornélia Kajáry, Zsolt Lengyel, Anna-Mária Tőkés, Janina Kulka, Magdolna Dank, Tímea Tőkés
MicroRNA-182-5p Modulates Oral Squamous Cell Carcinoma Migration and Invasion Via Targeting MTSS1 Gene
Yan Guo, Xue Qiao, Li Zhu, Rongbo Song
C-X-C Chemokine Receptor Type 7 (CXCR-7) Expression in Invasive Ductal Carcinoma of Breast in Association with Clinicopathological Features
Roshanak Shams, Mahnaz Seifi-Alan, Mojgan Bandehpour, Mir Davood Omrani, Soudeh Ghafouri-Fard
lncRNA SNHG16 Exerts Oncogenic Functions in Promoting Proliferation of Glioma Through Suppressing p21
Xiang-Yang Zhou, Hong Liu, Zheng-Bin Ding, Hai-Peng Xi, Guang-Wei Wang
Differential Analysis of lncRNA, miRNA and mRNA Expression Profiles and the Prognostic Value of lncRNA in Esophageal Cancer
Hongtao Liu, Qing Zhang, Qianqian Lou, Xin Zhang, Yunxia Cui, Panpan Wang, Fan Yang, Fan Wu, Jing Wang, Tianli Fan, Shenglei Li
Identification of Pathogenic Genes and Transcription Factors in Osteosarcoma
Chenggang Yang, Di Huang, Cui Ma, Jing Ren, Lina Fu, Cheng Cheng, Bangling Li, Xiaofeng Shi
Prognostic Significance of Serum PSA Level and Telomerase, VEGF and GLUT-1 Protein Expression for the Biochemical Recurrence in Prostate Cancer Patients after Radical Prostatectomy
Anna Gasinska, Janusz Jaszczynski, Urszula Rychlik, Elżbieta Łuczynska, Marek Pogodzinski, Mikolaj Palaczynski
Comparison of CDH1 Gene Hypermethylation Status in Blood and Serum among Gastric Cancer Patients
Zhi Li, Zhiqiang Guo
Identifying Potential Prognostic Markers for Muscle-Invasive Bladder Urothelial Carcinoma by Weighted Gene Co-Expression Network Analysis
Yueyi Feng, Yiqing Jiang, Tao Wen, Fang Meng, Xiaochen Shu
All Benign and Malignant Apocrine Breast Lesions Over-Express Claudin 1 and 3 and Are Negative for Claudin 4
Sami Shousha, Oliver Anscombe, Taneisha McFarlane
Silencing UHRF1 Inhibits Cell Proliferation and Promotes Cell Apoptosis in Retinoblastoma Via the PI3K/Akt Signalling Pathway
Yang Liu, Guodong Liang, Tingting Zhou, Zengshan Liu
Distinct Angiogenic microRNA-mRNA Expression Profiles Among Subtypes of Lung Adenocarcinoma
Laura Boldrini, Mirella Giordano, Franca Melfi, Marco Lucchi, Gabriella Fontanini
Clinicopathologic Diagnostic and Prognostic Factors of Spindle Cell Carcinoma of Upper Airway
Amanda Bueno de Araújo, Thiago Luís Infanger Serrano, Maria Cláudia Mota Pedroso, Fernanda Viviane Mariano, Albina Altemani, Flavio Mignone Gripp, Agrício Nubiato Crespo, Carlos Takahiro Chone
Predictive Value of ERCC1, ERCC2, and XRCC Expression for Patients with Locally Advanced or Metastatic Gastric Cancer Treated with Neoadjuvant mFOLFOX-4 Chemotherapy
Yung-Sung Yeh, Yi-Ting Chen, Hsiang-Lin Tsai, Ching-Wen Huang, Cheng-Jen Ma, Wei-Chih Su, Chun-Ming Huang, Ming-Yii Huang, Huang-Ming Hu, Chien-Yu Lu, Jaw-Yuan Wang
Effect of COPD on Inflammation, Lymphoid Functions and Progression-Free Survival during First-Line Chemotherapy in Advanced Non-small Cell Lung Cancer
Márton Szentkereszty, Zsolt István Komlósi, Gergő Szűcs, Gábor Barna, Lilla Tamási, György Losonczy, Gabriella Gálffy
Adaptation of Fatigue Affected Changes in Muscle EMG Frequency Characteristics for the Determination of Training Load in Physical Therapy for Cancer Patients
Adam Hegedus, Lukasz Trzaskoma, Peter Soldos, Kornelia Tuza, Peter Katona, Zsolt Greger, Fanni Zsarnoczky-Dulhazi, Bence Kopper
The Effect of Next-Generation TKI in Non-Small Cell Lung Cancer after Failure of First-Line Treatment: a Meta-Analysis
Lei Zhang, Hong-Wei Ren, Qi-Long Wu, Yan-Juan Wu, Xiang Song
Tissue HE4 Expression Discriminates the Ovarian Serous Carcinoma but Not the Uterine Serous Carcinoma Patients. A New Adjunct to the Origin of the Tumor Site
Betul Celik, Tangul Bulut, Arzu Didem Yalcin
CUL1 Knockdown Attenuates the Adhesion, Invasion, and Migration of Triple-Negative Breast Cancer Cells via Inhibition of Epithelial-Mesenchymal Transition
Ze-Qiang Ren, Wen-Jing Yan, Xiu-Zhong Zhang, Peng-Bo Zhang, Chong Zhang, Shou-Kun Chen
Evaluation of Alpha 1-Antitrypsin for the Early Diagnosis of Colorectal Cancer
Hajar Jaberie, Seyed Vahid Hosseini, Fakhraddin Naghibalhossaini
p63 Expression and its Relation to Epithelial Cells Proliferation in Dentigerous Cyst, Odontogenic Keratocyst, and Ameloblastoma
Mohammed Amjed Alsaegh, Alaa Muayad Altaie, Shengrong Zhu
Prognostic Value of Accumulative Expression of COX-2 and p53 in Small and Diffuse Large B Cell Lymphoma
Amen H. Zaky, Dalia Elsers, Rania Bakry, Mostafa Abdelwanis, Ola Nabih, Rania Hafez, Mahmoud Rezk
Comprehensive Data of P53 R282 Gene Mutation with Human Papillomaviruses (HPV)-Associated Oral Squamous Cell Carcinoma (OSCC)
Tipaya Ekalaksananan, Weerayut Wongjampa, Pensiri Phusingha, Jureeporn Chuerduangphui, Patravoot Vatanasapt, Supannee Promthet, Natcha Patarapadungkit, Chamsai Pientong
The Role of O6-methylguanine-DNA Methyltransferase Polymorphisms in Prostate Cancer Susceptibility: a Meta-Analysis
Wei Zhang, Mingkai Liu, Yue Li, Shichao Song, Kai Li, Yongliang Ma
Intensity of Nuclear Staining for Ki-67, p53 and Survivin as a New Prognostic Factor in Non-muscle Invasive Bladder Cancer
Rafał Stec, Szczepan Cierniak, Arkadiusz Lubas, Urszula Brzóskowska, Tomasz Syryło, Henryk Zieliński, Aleksandra Semeniuk-Wojtaś
The Relationship Between Tumor-Infiltrating Lymphocytes, PD-L1 Expression, Driver Mutations and Clinical Outcome Parameters in Non-Small Cell Lung Cancer Adenocarcinoma in Patients with a Limited to no Smoking History
Sacha Mignon, Karen Willard-Gallo, Gert Van den Eynden, Roberto Salgado, Lore Decoster, Koen M. Marien, Johan F. Vansteenkiste, Erik Teugels, Jacques De Grève
Absence of EGFR C797S Mutation in Tyrosine Kinase Inhibitor-Naïve Non–Small Cell Lung Cancer Tissues
Igor P. Oscorbin, Alexandra S. Shadrina, Vadim V. Kozlov, Vladimir E. Voitsitsky, Maxim L. Filipenko
Association between Genetic Polymorphisms in microRNA Machinery Genes and Risk of Papillary Thyroid Carcinoma
Abbas Mohammadpour-Gharehbagh, Zahra Heidari, Moein Eskandari, Abtin Aryan, Saeedeh Salimi
STIP1 Tissue Expression Is Associated with Survival in Chemotherapy-Treated Bladder Cancer Patients
U. Krafft, S. Tschirdewahn, J. Hess, N. N. Harke, B. A. Hadaschik, P. Nyirády, A. Szendröi, M. Szücs, O. Módos, C. Olah, E. Székely, H. Reis, Tibor Szarvas
A Single Nucleotide Polymorphism in GAS5 lncRNA is Associated with Risk of Bladder Cancer in Iranian Population
Azadeh Rakhshan, Mohammad Hossein Esmaeili, Mir Salar Kahaei, Mohammad Taheri, Mir Davood Omrani, Rezvan Noroozi, Soudeh Ghafouri-Fard
The Association between Epidermal Growth Factor Receptor Single Nucleotide Polymorphisms and Radiochemotherapy Response in Cervical Cancer
Ge Jin, Xiao-Mei Fan, Kui-Xiu Li, Shu-Huai Niu, Qian-Ying Zhang
Immunological and Clinicopathological Significance of MFG-E8 Expression in Patients with Oral Squamous Cell Carcinoma
Ayako Okamoto, Koichi Sakakura, Hideyuki Takahashi, Sei-ichiro Motegi, Kyoichi Kaira, Yuki Yokobori-Kuwabara, Osamu Ishikawa, Kazuaki Chikamatsu
High Expression of Angiopoietin-like Protein 4 in Advanced Colorectal Cancer and its Association with Regulatory T Cells and M2 Macrophages
Shuaiyang Zhou, Jin Tu, Shizhen Ding, Guotao Lu, Zhijie Lin, Yanbing Ding, Bing Deng, Yu Zhang, Weiming Xiao, Weijuan Gong
Peptidyl Arginine Deiminase, Type II (PADI2) Is Involved in Urothelial Bladder Cancer
Bao-shan Gao, Chun-shu Rong, Hong-mei Xu, Tao Sun, Jie Hou, Ying Xu
AF1q Expression Associates with CD44 and STAT3 and Impairs Overall Survival in Adenoid Cystic Carcinoma of the Head and Neck
Lorenz C. Kadletz, Faris F. Brkic, Bernhard J. Jank, Sven Schneider, Julia Cede, Rudolf Seemann, Elisabeth S. Gruber, Elisabeth Gurnhofer, Gregor Heiduschka, Lukas Kenner
Molecular Network-Based Identification of Circular RNA-Associated ceRNA Network in Papillary Thyroid Cancer
Qin Liu, Liang-zhi Pan, Min Hu, Jian-ying Ma
Upregulation of RUNX1 Suppresses Proliferation and Migration through Repressing VEGFA Expression in Hepatocellular Carcinoma
Chao Liu, Dingwei Xu, Bai Xue, Bolin Liu, Jing Li, Jie Huang
Spinal Versus Intracranial Meningioma: Aberrant Expression of CD10 and Inhibin with Relation to Clinicopathological Features and Prognosis
Abd AlRahman Mohammad Foda, Samia Rafi, Nadeem Ikram, Mariya Syed Alam, Sana Ayesha
Lactate Dehydrogenase-to-Lymphocyte Ratio Represents a Powerful Prognostic Tool of Metastatic Renal Cell Carcinoma Patients Treated with Tyrosine Kinase Inhibitors
Tao Li, Heng Li, Sheng Xie, Yan Tan, Zi-Ping Xie, Wen-Yi Li, Fen Ai
Role of Peritoneal Cytology in Patients with Early Stage Colorectal Cancer
Isabel María Gallarín Salamanca, M. T. Espín Jaime, J. M. Moran Penco, J. Salas Martínez
Expressions of Carbohydrate Response Element Binding Protein and Glucose Transporters in Liver Cancer and Clinical Significance
Yu Lei, Qiaoling Hu, Jiang Gu
Human Papillomavirus Detection Strategies in Retinoblastoma
Sheetal Chauhan, Seema Sen, Neeta Singh, Anjana Sharma, Bhavna Chawla, Seema Kashyap
Analysis of Promoter Mutation in Long Non-coding RNA NEAT1 in Acute Leukemias
Ha Yoon Mo, Eun Ha Jeon, Min Sung Kim, Nam Jin Yoo, Sug Hyung Lee
Epstein-Barr Virus MicroRNAs in Nasopharyngeal Carcinoma
Evangelos Tsiambas, Nicholas S. Mastronikolis, Panagiotis P. Fotiades, Vasileios Ragos, Nikolaos Kavantzas, Andreas C. Lazaris
Intravascular Occlusion by Leukemic Blast Cells Causing Multiplex Hand Necrosis in a Patient with Acute Myeloid Leukemia
László Pinczés, Ferenc Magyari, Gyula Reményi, György Pfliegler, Sándor Barna, Judit Bedekovics, Árpád Illés
The Potential Role of Organoids in Pathology and Oncology Research
S. Satish Kumar, Sreena Nellimad Sreedharan, Shankargouda Patil, A. Thirumal Raj
Immune Checkpoint Inhibitors in Small Cell Lung Cancer: Is It Also a Matter of Helios− Cells?
Raffaella Mormile
Immune Checkpoint Inhibitor Therapy in HIV-Positive Patients with Advanced-Stage Cancer: a Golden Card to Be Played?
Raffaella Mormile
Body Fat and Risk of Breast Cancer in Postmenopausal Women: What Is the Truth?
Raffaella Mormile
Total Serum Cholesterol and Pancreatic Cancer Risk: What Is the Link?
Raffaella Mormile
Aspirin Use and Risk of Glioma: a Double Track for a Single Goal?
Raffaella Mormile
Statin Therapy and Survival among Women with Ovarian Cancer: how much of it Is True?
Raffaella Mormile