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Erschienen in: Dysphagia 3/2016

20.04.2016 | Review Paper

Pathophysiology of Radiation-Induced Dysphagia in Head and Neck Cancer

verfasst von: Suzanne N. King, Neal E. Dunlap, Paul A. Tennant, Teresa Pitts

Erschienen in: Dysphagia | Ausgabe 3/2016

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Abstract

Oncologic treatments, such as curative radiotherapy and chemoradiation, for head and neck cancer can cause long-term swallowing impairments (dysphagia) that negatively impact quality of life. Radiation-induced dysphagia comprised a broad spectrum of structural, mechanical, and neurologic deficits. An understanding of the biomolecular effects of radiation on the time course of wound healing and underlying morphological tissue responses that precede radiation damage will improve options available for dysphagia treatment. The goal of this review is to discuss the pathophysiology of radiation-induced injury and elucidate areas that need further exploration.
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Metadaten
Titel
Pathophysiology of Radiation-Induced Dysphagia in Head and Neck Cancer
verfasst von
Suzanne N. King
Neal E. Dunlap
Paul A. Tennant
Teresa Pitts
Publikationsdatum
20.04.2016
Verlag
Springer US
Erschienen in
Dysphagia / Ausgabe 3/2016
Print ISSN: 0179-051X
Elektronische ISSN: 1432-0460
DOI
https://doi.org/10.1007/s00455-016-9710-1

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