Skip to main content
Hauptrubriken
CME Facharzt-Training Webinare Zeitschriften Bücher e.Medpedia Podcast
Service
Jobbörse Info & Hilfe
Fachgebiete
Anästhesiologie Allgemeinmedizin Arbeitsmedizin Augenheilkunde Chirurgie Dermatologie Gynäkologie und Geburtshilfe HNO Innere Medizin Kardiologie Neurologie Onkologie und Hämatologie Orthopädie und Unfallchirurgie Pädiatrie Pathologie Psychiatrie Radiologie Rechtsmedizin Urologie Zahnmedizin
Themen
Klimawandel und Gesundheit Neues aus dem Markt COVID-19 Praxis und Beruf Seltene Erkrankungen GOÄ & EBM Panorama
Sammlungen
Kasuistiken Algorithmen & Infografiken Blickdiagnosen Arthropedia FlapFinder (für Dermatochirurgen) Videos Kongressberichterstattung Medizin für Apothekerinnen und Apotheker Für Ärztinnen und Ärzte in Weiterbildung Für Medizinstudierende
Erweiterte Suche
Anmelden
nach oben
Current Hematologic Malignancy Reports
Erschienen in: Current Hematologic Malignancy Reports 4/2017

01.06.2017 | Health Economics (N Khera, Section Editor)

Patient and Caregiver Adjustment to Hematopoietic Stem Cell Transplantation: a Systematic Review of Dyad-Based Studies

verfasst von: Shelby Langer, Christine Lehane, Jean Yi

Erschienen in: Current Hematologic Malignancy Reports | Ausgabe 4/2017

Einloggen, um Zugang zu erhalten

Abstract

Purpose of Review

The aims of this study were to identify and systematically evaluate studies published from 2005–2017 that took a dyadic approach to assessing or intervening upon hematopoietic cell transplant (HCT) recipients and their informal caregivers.

Recent Findings

Our search yielded 20 studies. Regarding sample demographic characteristics, most participants were Caucasian and most caregivers were related to the patient by marriage. Regarding design characteristics, 18 studies were quantitative and two were qualitative; five were cross-sectional, ten were longitudinal, one was experimental, and four were interventional. Most outcomes were psychosocial and the interventions were largely psycho-educational in nature. Large variation in quality of the studies emerged (six were rated as low quality, seven as adequate, and seven as high quality).

Summary

Understudied populations include racial/ethnic minorities and same-sex couples. More work is needed to understand functioning during survivorship and impacts on patient medical outcomes, and to truly leverage the dyad to optimize individual- and relationship-level adjustment.
Literatur
1.
Niederwieser D, Baldomero H, Szer J, Gratwohl M, Atsuta Y, Bouzas L, et al. Hematopoietic stem cell transplantation activity worldwide in 2012 and a SWOT analysis of the Worldwide Network for Blood and Marrow Transplantation Group including the global survey. Bone Marrow Transpl. 2016;51:778–85.CrossRef
2.
3.
Martin P, Counts G, Appelbaum F, Lee S, Sanders J, Deeg H, et al. Life expectancy in patients surviving more than 5 years after hematopoietic cell transplantation. J Clin Oncol. 2010;28:1011–6.CrossRefPubMedPubMedCentral
4.
Syrjala KL, Martin P, Deeg J, Boeckh M. Medical and psychosocial issues in transplant survivors. In: Chang AE, Ganz PA, Hayes DF, Kinsella T, Pass HI, Schiller JH, et al., editors. Oncology: an evidence-based approach. New York, NY: Springer Science + Business Media, Inc; 2006:1902–1928.
5.
Andrykowski MA, Bishop MM, Hahn EA, Cella DF, Beaumont JL, Brady MJ, et al. Long-term health-related quality of life, growth, and spiritual well-being after hematopoietic stem-cell transplantation. J Clin Oncol. 2005;23:599–608.CrossRefPubMed
6.
Andrykowski MA, Cordova MJ, Hann DM, Jacobsen PB, Fields KK, Phillips G. Patients’ psychosocial concerns following stem cell transplantation. Bone Marrow Transpl. 1999;24:1121–9.CrossRef
7.
Mosher C, DuHamel K, Rini C, Corner G, Lam J, Redd W. Quality of life concerns and depression among hematopoietic stem cell transplant survivors. Support Care Cancer. 2011;19:1357–65.CrossRefPubMed
8.
Noerskov K, Schjodt I, Syrjala K, Jarden M. Sexual function 1-year after allogeneic hematopoietic stem cell transplantation. Bone Marrow Transpl. 2016;51:833–40.CrossRef
9.
Syrjala KL, Langer SL, Abrams JR, Storer B, Sanders JE, Flowers ME, et al. Recovery and long-term function after hematopoietic cell transplantation for leukemia or lymphoma. JAMA. 2004;291:2335–43.CrossRefPubMed
10.
Yokoe D, Casper C, Dubberke E, Lee G, Munoz P, Palmore T, et al. Safe living after hematopoietic cell transplantation. Bone Marrow Transpl. 2009;44:509–19.CrossRef
11.
Gemmill R, Cooke L, Williams A, Grant M. Informal caregivers of hematopoeitic cell transplant patients: a review and recommendations for interventions and research. Cancer Nurs. 2011;34:E13–21.CrossRefPubMedPubMedCentral
12.
Bishop MM, Beaumont JL, Hahn EA, Cella D, Andrykowski MA, Brady MJ, et al. Late effects of cancer and hematopoietic stem-cell transplantation on spouses or partners compared with survivors and survivor-matched controls. J Clin Oncol. 2007;25:1403–11.CrossRefPubMed
13.
Gaston-Johansson F, Lachica E, Fall-Dickson J, Kennedy M. Psychological distress, fatigue, burden of care, and quality of life in primary caregivers of patients with breast cancer undergoing autologous bone marrow transplantation. Oncol Nurs Forum. 2004;31:1161–9.CrossRefPubMed
14.
Wilson ME, Eilers J, Heermann JA, Million R. The experience of spouses as informal caregivers for recipients of hematopoietic stem cell transplants. Cancer Nurs. 2009;32:E15–23.CrossRefPubMed
15.
Zabora JR, Smith ED, Baker F, Wingard JR, Curbow B. The family: the other side of bone marrow transplantation. J Psychosoc Oncol. 1992;10:35–46.CrossRef
16.
Langer S, Abrams J, Syrjala K. Caregiver and patient marital satisfaction and affect following hematopoietic stem cell transplantation: a prospective, longitudinal investigation. Psychooncology. 2003;12:239–53.CrossRefPubMed
17.
Akgul N, Ozdemir L. Caregiver burden among primary caregivers of patients undergoing peripheral blood stem cell transplantation: a cross sectional study. Eur J Oncol Nurs. 2014;18:372–7.CrossRefPubMed
18.
Langer SL, Yi JC, Storer BE, Syrjala KL. Marital adjustment, satisfaction and dissolution among hematopoietic stem cell transplant patients and spouses: a prospective, five-year longitudinal investigation. Psychooncology. 2010;19:190–200.CrossRefPubMedPubMedCentral
19.
Prieto J, Blanch J, Atala J, Carreras E, Rovira M, Cirera E, et al. Stem cell transplantation: risk factors for psychiatric morbidity. Eur J Cancer. 2006;42:514–20.CrossRefPubMed
20.
Fowkes F, Fulton P. Critical appraisal of published research: introductory guidelines. Br Med J. 1991;302:1136–40.CrossRef
21.
Lehane C, Dammeyer J, Elsass P. Sensory loss and its consequences for couples’ psychosocial and relational wellbeing: an integrative review. Aging Ment Health. 2016;21:337–47.CrossRefPubMed
22.
de Bere S, Nunn S, Nasser M. Critical Appraisal Skills Programme (CASP) qualitative research checklist. 2015.
23.
24.
Majhail N, Rizzo J, Hahn T, Lee S, McCarthy P, Ammi M, et al. Pilot study of patient and caregiver out-of-pocket costs of allogeneic hematopoietic cell transplantation. Bone Marrow Transpl. 2013;48:865–71.CrossRef
25.
Denzen E, Thao V, Hahn T, Lee S, McCarthy P, Rizzo J, et al. Financial impact of allogeneic hematopoietic cell transplantation on patients and families over 2 years: results from a multicenter pilot study. Bone Marrow Transpl. 2016;51:1233–40.CrossRef
26.
Bishop M, Curbow B, Springer S, Lee J, Wingard J. Comparison of lasting life changes after cancer and BMT: perspectives of long-term survivors and spouses. Psychooncology. 2011;20:926–34.PubMed
27.
• Beattie S, Lebel S, Petricone-Westwood D, Wilson KG, Harris C, Devins G, Huebsch L, Tay J. Balancing give and take between patients and their spousal caregivers in hematopoietic stem cell transplantation. Psychooncology. 2017:Epub ahead of print. Examined the balance of “give-and-take” among patients and spousal caregivers, using equity theory as a conceptual framework.
28.
Bevans M, Castro K, Prince P, Shelburne N, Prachenko O, Loscalzo M, et al. An individualized dyadic problem-solving education intervention for patients and family caregivers during allogeneic hematopoietic stem cell transplantation. Cancer Nurs. 2010;33:E24–32.CrossRefPubMedPubMedCentral
29.
Bevans M, Wehrlen L, Prachenko O, Soeken K, Zabora J, Wallen GR. Distress screening in allogeneic hematopoietic stem cell (HSCT) caregivers and patients. Psychooncology. 2011;20:615–22.CrossRefPubMedPubMedCentral
30.
Bevans M, Wehrlen L, Castro K, Prince P, Shelburne N, Soeken K, et al. A problem-solving education intervention in caregivers and patients during allogeneic hematopoietic stem cell transplantation. J Health Psychol. 2014;19:602–17.CrossRefPubMed
31.
El-Jawahri A, Traeger L, Kuzmuk K, Eusebio J, Vandusen H, Shin J, et al. Quality of life and mood of patients and family caregivers during hospitalization for hematopoietic stem cell transplantation. Cancer. 2015;121:951–9.CrossRefPubMed
32.
• El-Jawahri A, LeBlanc T, VanDusen H, Traeger L, Greer J, Pirl W, et al. Effect of inpatient palliative care on quality of life 2 weeks after hematopoietic stem cell transplantation: a randomized clinical trial. JAMA. 2016;316:2094–103. Demonstrated short-term efficacy of an inpatient palliative care intervention relative to usual care. CrossRefPubMedPubMedCentral
33.
Fife B, Weaver M, Cook W, Stump T. Partner interdependence and coping with life-threatening illness: the impact on dyadic adjustment. J Fam Psychol. 2013;27:702–11.CrossRefPubMed
34.
Fife B, Von Ah D, Spath M, Weaver M, Yang Z, Stump T, et al. Preliminary efficacy of a brief family intervention to prevent declining quality of life secondary to parental bone marrow transplantation. Bone Marrow Transpl. 2017;52:285–91.CrossRef
35.
Harris M. Burden, uncertainty, and patient symptomatology in family caregivers of hematopoietic stem cell transplant patients: a prospective study. 2008.
36.
Langer SL, Rudd ME, Syrjala KL. Protective buffering and emotional desynchrony among spousal caregivers of cancer patients. Health Psychol. 2007;26:635–43.CrossRefPubMed
37.
38.
Little M, Jordens C, McGrath C, Montgomery K, Lipworth W, Kerridge I. Informed consent and medical ordeal: a qualitative study. Intern Med J. 2008;38:624–8.CrossRefPubMed
39.
Polomeni A, Lapusan S, Bompoint C, Rubio M, Mohty M. The impact of allogeneic-hematopoietic stem cell transplantation on patients’ and close relatives’ quality of life and relationships. Eur J Oncol Nurs. 2016:248–56.
40.
• Posluszny D, Bovbjerg D, Agha M, Hou J, Raptis A, Boyiadzis M et al. Patient and family caregiver dyadic adherence to the allogeneic hematopoietic cell transplantation medical regimen. Psychooncology. 2017; Epub ahead of print. Demonstrated associations between psychosocial factors (e.g., patient-caregiver relationship quality) and patient adherence to immunosuppressant medications.
41.
Sannes T, Mikulich-Gilbertson S, Natvig C, Brewer B, Simoneau T, Laudenslager M. Caregiver sleep and patient neutrophil engraftment in allogeneic hematopoietic stem cell transplant. Cancer Nurs. 2016; Epub ahead of print.
42.
43.
Boutron I, Moher D, Altman D, Schulz K, Ravaud P. Extending the CONSORT statement to randomized trials of nonpharmacologic treatment: explanation and elaboration. Ann Intern Med. 2008;148:295–309.CrossRefPubMed
44.
Von Elm E, Altman D, Egger M, Pocock S, Gotzsche P, Vandenbroucke J, et al. Strengthening the reporting of observational studies in epidemiology (STROBE) statement: guidelines for reporting observational studies. Int J Surg. 2014;12:1495–9.CrossRefPubMed
45.
Sun C, Francisco L, Baker K, Weisdorf D, Forman S, Bhatia S. Adverse psychological outcomes in long-term survivors of hematopoietic cell transplantation: a report from the Bone Marrow Transplant Survivor Study (BMTSS). Blood. 2011;118:4723–31.CrossRefPubMedPubMedCentral
46.
Gottman J, Levenson R, Swanson C, Swanson K, Tyson R, Yoshimoto D. Observing gay and lesbian and heterosexual couples’ relationships. J Homosex. 2003;45:65–91.CrossRefPubMed
47.
Pinquart M, Sorensen S. Spouses, adult children, and children-in-law as caregivers of older adults: a meta-analytic comparison. Psychol Aging. 2011;26:1–14.CrossRefPubMedPubMedCentral
48.
Shiffman S, Stone AA, Hufford MR. Ecological momentary assessment. Ann Rev Clin Psycho. 2008;4:1–32.CrossRef
49.
Burns J, Peterson K, Smith D, Keefe F, Porter L, Schuster E, et al. Temporal associations between spouse criticism/hostility and pain among patients with chronic pain: a within-couple daily diary study. Pain. 2013;154:2715–21.CrossRefPubMedPubMedCentral
50.
Porter L, Keefe F, Baucom D, Olsen M, Zafar S, Uronis H. A randomized pilot trial of a videoconference couples communication for advanced GI cancer. Psychooncology. 2016;
51.
Chang G, Ratichek S, Recklitis C, Syrjala K, Patel S, Harris L, et al. Children’s psychological distress during pediatric HSCT: parent and child perspectives. Pediatr Blood Cancer. 2012;58:289–96.CrossRefPubMed
52.
Wiener L, Baird K, Crum C, Powers K, Carpenter P, Baker K, et al. Child and parent perspectives of the chronic graft-versus-host disease (cGVHD) symptom experience: a concept elicitation study. Support Care Cancer. 2014;22:295–305.CrossRefPubMedPubMedCentral
53.
Kamsvag-Magnusson T, Thorsell-Cederberg J, Svanberg A, von Essen L, Arvidson J, Mellgren K, et al. Parents and children's perceptions of distress related to oral mucositis during hematopoietic stem cell transplantation. Acta Paediatr. 2014;103:630–6.CrossRefPubMedPubMedCentral
54.
Rodday A, Terrin N, Leslie L, Graham R, Parsons S. Understanding the relationship between child health-related quality of life and parent emotional functioning in pediatric hematopoietic stem cell transplant. J Pediatr Psychol. 2017;2017:1–11.
55.
Parsons S, Tighiouart H, Terrin N. Assessment of health-related quality of life in pediatric hematopoietic stem cell transplant recipients: progress, challenges and future directions. Exp Rev Pharmacoecon Outcomes Res. 2013;13:217–25.CrossRef
56.
57.
Lepore SJ. A social-cognitive processing model of emotional adjustment to cancer. In: Baum A, Andersen BL, editors. Psychosocial interventions for cancer. Washington, DC: American Psychological Association; 2001. p. 99–116.CrossRef
Metadaten
Titel
Patient and Caregiver Adjustment to Hematopoietic Stem Cell Transplantation: a Systematic Review of Dyad-Based Studies
verfasst von
Shelby Langer
Christine Lehane
Jean Yi
Publikationsdatum
01.06.2017
Verlag
Springer US
Erschienen in
Current Hematologic Malignancy Reports / Ausgabe 4/2017
Print ISSN: 1558-8211
Elektronische ISSN: 1558-822X
DOI
https://doi.org/10.1007/s11899-017-0391-0

Weitere Artikel der Ausgabe 4/2017

Current Hematologic Malignancy Reports 4/2017 Zur Ausgabe

Health Economics (N Khera, Section Editor)

Coordination of Care in Survivorship After Treatment of Hematological Malignancies—The Journey is Not Over Yet

CART and Immunotherapy (M Ruella, Section Editor)

Considerations in T Cell Therapy Product Development for B Cell Leukemia and Lymphoma Immunotherapy

B-cell NHL, T-cell NHL, and Hodgkin Lymphoma (D Persky, Section Editor)

Therapeutic Options for Aggressive T-Cell Lymphomas

Health Economics (N Khera, Section Editor)

Equal Treatment and Outcomes for Everyone with Multiple Myeloma: Are We There Yet?

B-cell NHL, T-cell NHL, and Hodgkin Lymphoma (D Persky, Section Editor)

An Update on the Use of Immunotherapy in the Treatment of Lymphoma

CART and Immunotherapy (M Ruella, Section Editor)

Novel Immunotherapies for Multiple Myeloma

Neu im Fachgebiet Onkologie

25.04.2024 | Nierenkarzinom | Nachrichten

Adjuvante Immuntherapie verlängert Leben bei RCC

25.04.2024 | NSCLC | Nachrichten

Alectinib verbessert krankheitsfreies Überleben bei ALK-positivem NSCLC

24.04.2024 | DGIM 2024 | Nachrichten

Bei Senioren mit Prostatakarzinom auf Anämie achten!

23.04.2024 | Medikamente in Schwangerschaft und Stillzeit | Nachrichten

ICI-Therapie in der Schwangerschaft wird gut toleriert
weitere anzeigen

Update Onkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen