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Erschienen in:

16.11.2023 | Original Article

Patient Characteristics and Severity Trajectories in a Pediatric Intermediate Care Unit

verfasst von: Marie E Lampin, Alain Duhamel, Hélène Béhal, Stephane Leteurtre, Francis Leclerc, Morgan Recher

Erschienen in: Indian Journal of Pediatrics | Ausgabe 2/2025

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Abstract

Objectives

To describe the characteristics of patients admitted to Pediatric Intermediate Care Units (PImCU) and to assess their illness severity trajectories.

Methods

This prospective, observational, multicentre cohort study was conducted in seven French PImCUs between September 2012 and January 2014. All consecutive patients aged under 18 were included. The severity of illness was evaluated through the Paediatric Advanced Warning Score (PAWS), measured every 8 h for each patient. A latent class mixed model was used to identify severity trajectory classes.

Results

A total of 2868 patients were included. The median [interquartile range] age was 29 [5–103] mo and the median length of stay was 1 [1–3] d. The primary indication for admission was respiratory (44%). Almost 3% of the patients were subsequently transferred to a pediatric intensive care unit. Three severity trajectory classes were identified. In one class, comprising the largest proportion of patients, the PAWS was low on admission and did not change markedly over time. In this class, patients were older and had a shorter length of stay. The other two classes were characterized by a higher PAWS on admission and rapid or slow improvement. These patients were more severely ill, mostly due to respiratory failure.

Conclusions

A large proportion of patients had a stable profile and no signs of severity which suggests that the stay in PImCU was not indicated but a part of these patients have remained stable perhaps because of the advanced monitoring and intensive nursing in these units.

Clinical Trial Registration

The study was registered with ClinicalTrials.gov Protocol, Identifier: NCT 02304341, ClinicalTrials.​gov.
Literatur
1.
Zurück zum Zitat Jaimovich DG, American Academy of Pediatrics Committee on Hospital Care and Section on Critical Care. Admission and discharge guidelines for the pediatric patient requiring intermediate care. Pediatrics. 2004;113:1430–3.CrossRefPubMed Jaimovich DG, American Academy of Pediatrics Committee on Hospital Care and Section on Critical Care. Admission and discharge guidelines for the pediatric patient requiring intermediate care. Pediatrics. 2004;113:1430–3.CrossRefPubMed
2.
Zurück zum Zitat Ettinger NA, Hill VL, Russ CM, et al. Guidance for structuring a pediatric intermediate care unit. Pediatrics. 2022;149:e2022057009.CrossRefPubMed Ettinger NA, Hill VL, Russ CM, et al. Guidance for structuring a pediatric intermediate care unit. Pediatrics. 2022;149:e2022057009.CrossRefPubMed
3.
Zurück zum Zitat Plate JDJ, Leenen LPH, Houwert M, Hietbrink F. Utilisation of intermediate care units: a systematic review. Crit Care Res Pract. 2017;2017:8038460.PubMedPubMedCentral Plate JDJ, Leenen LPH, Houwert M, Hietbrink F. Utilisation of intermediate care units: a systematic review. Crit Care Res Pract. 2017;2017:8038460.PubMedPubMedCentral
4.
Zurück zum Zitat Lambert V, Matthews A, MacDonell R, Fitzsimons J. Paediatric early warning systems for detecting and responding to clinical deterioration in children: a systematic review. BMJ Open. 2017;7:e014497.CrossRefPubMedPubMedCentral Lambert V, Matthews A, MacDonell R, Fitzsimons J. Paediatric early warning systems for detecting and responding to clinical deterioration in children: a systematic review. BMJ Open. 2017;7:e014497.CrossRefPubMedPubMedCentral
5.
Zurück zum Zitat Lampin ME, Duhamel A, Behal H, Recher M, Leclerc F, Leteurtre S. Use of paediatric early warning scores in intermediate care units. Arch Dis Child. 2020;105:173–9.PubMed Lampin ME, Duhamel A, Behal H, Recher M, Leclerc F, Leteurtre S. Use of paediatric early warning scores in intermediate care units. Arch Dis Child. 2020;105:173–9.PubMed
6.
Zurück zum Zitat Egdell P, Finlay L, Pedley DK. The PAWS score: validation of an early warning scoring system for the initial assessment of children in the emergency department. Emerg Med J. 2008;25:745–9.CrossRefPubMed Egdell P, Finlay L, Pedley DK. The PAWS score: validation of an early warning scoring system for the initial assessment of children in the emergency department. Emerg Med J. 2008;25:745–9.CrossRefPubMed
7.
Zurück zum Zitat McCulloch CE, Lin H, Slate EH, Turnbull BW. Discovering subpopulation structure with latent class mixed models. Stat Med. 2002;21:417–29.CrossRefPubMed McCulloch CE, Lin H, Slate EH, Turnbull BW. Discovering subpopulation structure with latent class mixed models. Stat Med. 2002;21:417–29.CrossRefPubMed
8.
Zurück zum Zitat Molenberghs G, Verbeke G. Chapter 9: General guidelines for model building. In: Molenberghs G, Verbeke G, editors. Linear mixed models for Longitudinal Data. New York: Springer Verlag; 2009. p. 121–34.CrossRef Molenberghs G, Verbeke G. Chapter 9: General guidelines for model building. In: Molenberghs G, Verbeke G, editors. Linear mixed models for Longitudinal Data. New York: Springer Verlag; 2009. p. 121–34.CrossRef
9.
Zurück zum Zitat Molenberghs G, Verbeke G. Chapter 10: exploring serial correlation. In: Molenberghs G, Verbeke G, editors. Linear mixed models for Longitudinal Data. New York: Springer Verlag; 2009. p. 135–50.CrossRef Molenberghs G, Verbeke G. Chapter 10: exploring serial correlation. In: Molenberghs G, Verbeke G, editors. Linear mixed models for Longitudinal Data. New York: Springer Verlag; 2009. p. 135–50.CrossRef
10.
Zurück zum Zitat van de Schoot R, Sijbrandij M, Winter SD, Depaoli S, Vermunt JK. The GRoLTS-checklist: guidelines for reporting on latent trajectory studies. Struct Equ Model Multidiscip J. 2017;24:451–67.CrossRef van de Schoot R, Sijbrandij M, Winter SD, Depaoli S, Vermunt JK. The GRoLTS-checklist: guidelines for reporting on latent trajectory studies. Struct Equ Model Multidiscip J. 2017;24:451–67.CrossRef
11.
Zurück zum Zitat Proust-Lima C, Philipps V, Liquet B. Estimation of extended mixed models using latent classes and latent processes: the R package lcmm. J Stat Softw. 2017;78:1–56.CrossRef Proust-Lima C, Philipps V, Liquet B. Estimation of extended mixed models using latent classes and latent processes: the R package lcmm. J Stat Softw. 2017;78:1–56.CrossRef
12.
Zurück zum Zitat Sfriso F, Biban P, Paglietti MG, of the Paediatric Intermediate Care Unit Working Group of the Medical and Nursing Academy of Paediatric Emergency and Intensive Care, et al. Distribution and characteristics of Italian paediatric intermediate care units in Italy: a national survey. Acta Paediatr. 2020;109:1062–3.CrossRefPubMed Sfriso F, Biban P, Paglietti MG, of the Paediatric Intermediate Care Unit Working Group of the Medical and Nursing Academy of Paediatric Emergency and Intensive Care, et al. Distribution and characteristics of Italian paediatric intermediate care units in Italy: a national survey. Acta Paediatr. 2020;109:1062–3.CrossRefPubMed
13.
Zurück zum Zitat Cheng DR, Hui C, Langrish K, Beck CE. Anticipating pediatric patient transfers from intermediate to intensive care. Hosp Pediatr. 2020;10:347–52.CrossRefPubMed Cheng DR, Hui C, Langrish K, Beck CE. Anticipating pediatric patient transfers from intermediate to intensive care. Hosp Pediatr. 2020;10:347–52.CrossRefPubMed
14.
Zurück zum Zitat Slater A, Shann F, Pearson G. Paediatric Index of Mortality (PIM) Study Group. PIM2: a revised version of the Paediatric Index of Mortality. Intensive Care Med. 2003;29:278–85.CrossRefPubMed Slater A, Shann F, Pearson G. Paediatric Index of Mortality (PIM) Study Group. PIM2: a revised version of the Paediatric Index of Mortality. Intensive Care Med. 2003;29:278–85.CrossRefPubMed
15.
Zurück zum Zitat Russ CM, Agus M. Triage of intermediate-care patients in pediatric hospitals. Hosp Pediatr. 2015;5:542–7.CrossRefPubMed Russ CM, Agus M. Triage of intermediate-care patients in pediatric hospitals. Hosp Pediatr. 2015;5:542–7.CrossRefPubMed
16.
Zurück zum Zitat Hubert A, Ford-Chessel C, Berthiller J, Peretti N, Javouhey E, Valla FV. [Nutritional status in pediatric intermediate care: assessment at admission, progression during the stay and after discharge]. Arch Pediatr. 2016;23:333–9.CrossRefPubMed Hubert A, Ford-Chessel C, Berthiller J, Peretti N, Javouhey E, Valla FV. [Nutritional status in pediatric intermediate care: assessment at admission, progression during the stay and after discharge]. Arch Pediatr. 2016;23:333–9.CrossRefPubMed
17.
Zurück zum Zitat Hamze-Sinno R, Abdoul H, Neve M, Tsapis M, Jones P, Dauger S. Can we easily anticipate on admission pediatric patient transfers from intermediate to intensive care? Minerva Anestesiol. 2011;77:1022–3.PubMed Hamze-Sinno R, Abdoul H, Neve M, Tsapis M, Jones P, Dauger S. Can we easily anticipate on admission pediatric patient transfers from intermediate to intensive care? Minerva Anestesiol. 2011;77:1022–3.PubMed
18.
Zurück zum Zitat Gatti H, Dauger S, Sommet J, Chenel C, Naudin J. [Pediatric intermediate care unit in general hospital: recent survey in French Polynesia]. Arch Pediatr. 2014;21:272–8.CrossRefPubMed Gatti H, Dauger S, Sommet J, Chenel C, Naudin J. [Pediatric intermediate care unit in general hospital: recent survey in French Polynesia]. Arch Pediatr. 2014;21:272–8.CrossRefPubMed
20.
Zurück zum Zitat Porath A, Reuveni H, Grinberg G, Lieberman D. The intermediate care unit as a cost-effective option for the treatment of medical patients in critical condition. Isr J Med Sci. 1995;31:674–80.PubMed Porath A, Reuveni H, Grinberg G, Lieberman D. The intermediate care unit as a cost-effective option for the treatment of medical patients in critical condition. Isr J Med Sci. 1995;31:674–80.PubMed
21.
Zurück zum Zitat Junker C, Zimmerman JE, Alzola C, Draper EA, Wagner DP. A multicenter description of intermediate-care patients: comparison with ICU low-risk monitor patients. Chest. 2002;121:1253–61.CrossRefPubMed Junker C, Zimmerman JE, Alzola C, Draper EA, Wagner DP. A multicenter description of intermediate-care patients: comparison with ICU low-risk monitor patients. Chest. 2002;121:1253–61.CrossRefPubMed
22.
Zurück zum Zitat Solberg BCJ, Dirksen CD, Nieman FHM, van Merode G, Poeze M, Ramsay G. Changes in hospital costs after introducing an intermediate care unit: a comparative observational study. Crit Care. 2008;12:R68.CrossRefPubMedPubMedCentral Solberg BCJ, Dirksen CD, Nieman FHM, van Merode G, Poeze M, Ramsay G. Changes in hospital costs after introducing an intermediate care unit: a comparative observational study. Crit Care. 2008;12:R68.CrossRefPubMedPubMedCentral
23.
Zurück zum Zitat Geneslaw AS, Jia H, Lucas AR, Agus MSD, Edwards JD. Pediatric intermediate care and pediatric intensive care units: PICU metrics and an analysis of patients that use both. J Crit Care. 2017;41:268–74.CrossRefPubMedPubMedCentral Geneslaw AS, Jia H, Lucas AR, Agus MSD, Edwards JD. Pediatric intermediate care and pediatric intensive care units: PICU metrics and an analysis of patients that use both. J Crit Care. 2017;41:268–74.CrossRefPubMedPubMedCentral
24.
Zurück zum Zitat Lewis KM, Parekh SM, Ramnarayan P, Gilbert R, Hardelid P, Wijlaars L. Emergency paediatric critical care in England: describing trends using routine hospital data. Arch Dis Child. 2020;105:1061–7.CrossRefPubMed Lewis KM, Parekh SM, Ramnarayan P, Gilbert R, Hardelid P, Wijlaars L. Emergency paediatric critical care in England: describing trends using routine hospital data. Arch Dis Child. 2020;105:1061–7.CrossRefPubMed
Metadaten
Titel
Patient Characteristics and Severity Trajectories in a Pediatric Intermediate Care Unit
verfasst von
Marie E Lampin
Alain Duhamel
Hélène Béhal
Stephane Leteurtre
Francis Leclerc
Morgan Recher
Publikationsdatum
16.11.2023
Verlag
Springer India
Erschienen in
Indian Journal of Pediatrics / Ausgabe 2/2025
Print ISSN: 0019-5456
Elektronische ISSN: 0973-7693
DOI
https://doi.org/10.1007/s12098-023-04902-4

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