Skip to main content
Erschienen in: Supportive Care in Cancer 5/2019

15.08.2018 | Original Article

Patients with head and neck cancer may need more intensive pain management to maintain daily functioning: a multi-center study

verfasst von: Shih-Feng Cho, Kun-Ming Rau, Yu-Yun Shao, Chia-Jui Yen, Ming-Fang Wu, Jen-Shi Chen, Cheng-Shyong Chang, Su-Peng Yeh, Tzeon-Jye Chiou, Ruey-Kuen Hsieh, Ming-Yang Lee, Yung-Chuan Sung, Kuan-Der Lee, Pang-Yu Lai, Ming-Sun Yu, Wen-Li Hwang, Ta-Chih Liu

Erschienen in: Supportive Care in Cancer | Ausgabe 5/2019

Einloggen, um Zugang zu erhalten

Abstract

Purpose

The purpose of this study is to investigate the prevalence of pain, pain management, and impact of recent pain on daily functioning in patients with head and neck cancer (HNC) and patients with other cancers.

Methods

This multi-center survey was conducted by using Brief Pain Inventory questionnaire to evaluate pain status and its impact on daily functioning.

Results

A total of 3289 patients were analyzed including 708 HNC patients and 2581 patients with other cancers. The overall pain prevalence was 69.17%. A higher percentage of HNC patients had recent pain (60.59 vs. 44.01%, P < 0.001), required pain management (86.29 vs. 72.03%, P < 0.001), and used any analgesics (53.81 vs. 34.52%, P < 0.001). HNC patients with pain management had a higher prevalence of recent pain (85.83 vs. 81.14%, P = 0.044) and a slightly lower satisfaction rate (74.00 vs. 79.70%, P = 0.070). Regarding the impact of pain on daily functioning, HNC patients had a lower mean interference score for general activity such as walking, normal work, sleep, and life enjoyment.

Conclusions

The HNC patients may need more intensive pain management to achieve optimal pain control and maintain daily functioning.
Anhänge
Nur mit Berechtigung zugänglich
Literatur
1.
Zurück zum Zitat Blank FS, Mader TJ, Wolfe J, Keyes M, Kirschner R, Provost D (2001) Adequacy of pain assessment and pain relief and correlation of patient satisfaction in 68 ED fast-track patients. J Emerg Nurs 27:327–334CrossRefPubMed Blank FS, Mader TJ, Wolfe J, Keyes M, Kirschner R, Provost D (2001) Adequacy of pain assessment and pain relief and correlation of patient satisfaction in 68 ED fast-track patients. J Emerg Nurs 27:327–334CrossRefPubMed
2.
Zurück zum Zitat Bozimowski G (2012) Patient perceptions of pain management therapy: a comparison of real-time assessment of patient education and satisfaction and registered nurse perceptions pain. Manag Nurs 13:186–193 Bozimowski G (2012) Patient perceptions of pain management therapy: a comparison of real-time assessment of patient education and satisfaction and registered nurse perceptions pain. Manag Nurs 13:186–193
3.
Zurück zum Zitat Bradley PJ (2012) Multidisciplinary clinical approach to the management of head and neck cancer. Eur Arch Otorhinolaryngol 269:2451–2454CrossRefPubMed Bradley PJ (2012) Multidisciplinary clinical approach to the management of head and neck cancer. Eur Arch Otorhinolaryngol 269:2451–2454CrossRefPubMed
4.
Zurück zum Zitat Brana I, Siu LL (2012) Locally advanced head and neck squamous cell cancer: treatment choice based on risk factors and optimizing drug prescription. Ann Oncol 23(Suppl 10):x178–x185CrossRefPubMed Brana I, Siu LL (2012) Locally advanced head and neck squamous cell cancer: treatment choice based on risk factors and optimizing drug prescription. Ann Oncol 23(Suppl 10):x178–x185CrossRefPubMed
5.
Zurück zum Zitat Breivik H, Cherny N, Collett B, de Conno F, Filbet M, Foubert AJ, Cohen R, Dow L (2009) Cancer-related pain: a pan-European survey of prevalence, treatment, and patient attitudes. Ann Oncol 20:1420–1433CrossRefPubMed Breivik H, Cherny N, Collett B, de Conno F, Filbet M, Foubert AJ, Cohen R, Dow L (2009) Cancer-related pain: a pan-European survey of prevalence, treatment, and patient attitudes. Ann Oncol 20:1420–1433CrossRefPubMed
6.
Zurück zum Zitat Burton AW, Fanciullo GJ, Beasley RD, Fisch MJ (2007) Chronic pain in the cancer survivor: a new frontier. Pain Med 8:189–198CrossRefPubMed Burton AW, Fanciullo GJ, Beasley RD, Fisch MJ (2007) Chronic pain in the cancer survivor: a new frontier. Pain Med 8:189–198CrossRefPubMed
7.
Zurück zum Zitat Chaplin JM, Morton RP (1999) A prospective, longitudinal study of pain in head and neck cancer patients. Head Neck 21:531–537CrossRefPubMed Chaplin JM, Morton RP (1999) A prospective, longitudinal study of pain in head and neck cancer patients. Head Neck 21:531–537CrossRefPubMed
8.
Zurück zum Zitat Chen YJ, Chang JT, Liao CT, Wang HM, Yen TC, Chiu CC, Lu YC, Li HF, Cheng AJ (2008) Head and neck cancer in the betel quid chewing area: recent advances in molecular carcinogenesis. Cancer Sci 99:1507–1514CrossRef Chen YJ, Chang JT, Liao CT, Wang HM, Yen TC, Chiu CC, Lu YC, Li HF, Cheng AJ (2008) Head and neck cancer in the betel quid chewing area: recent advances in molecular carcinogenesis. Cancer Sci 99:1507–1514CrossRef
9.
Zurück zum Zitat Chiang CY, Chang HY (2016) A population study on the time trend of cigarette smoking, cessation, and exposure to secondhand smoking from 2001 to 2013 in Taiwan. Popul Health Metrics 14:38CrossRef Chiang CY, Chang HY (2016) A population study on the time trend of cigarette smoking, cessation, and exposure to secondhand smoking from 2001 to 2013 in Taiwan. Popul Health Metrics 14:38CrossRef
10.
Zurück zum Zitat Chua KS, Reddy SK, Lee MC, Patt RB (1999) Pain and loss of function in head and neck cancer survivors. J Pain Symptom Manag 18:193–202CrossRef Chua KS, Reddy SK, Lee MC, Patt RB (1999) Pain and loss of function in head and neck cancer survivors. J Pain Symptom Manag 18:193–202CrossRef
11.
Zurück zum Zitat Daut RL, Cleeland CS, Flanery RC (1983) Development of the Wisconsin Brief Pain Questionnaire to assess pain in cancer and other diseases. Pain 17:197–210CrossRefPubMed Daut RL, Cleeland CS, Flanery RC (1983) Development of the Wisconsin Brief Pain Questionnaire to assess pain in cancer and other diseases. Pain 17:197–210CrossRefPubMed
12.
Zurück zum Zitat De Sanctis V, Bossi P, Sanguineti G, Trippa F, Ferrari D, Bacigalupo A, Ripamonti CI, Buglione M, Pergolizzi S, Langendjik JA, Murphy B, Raber-Durlacher J, Russi EG, Lalla RV (2016) Mucositis in head and neck cancer patients treated with radiotherapy and systemic therapies: literature review and consensus statements. Crit Rev Oncol Hematol 100:147–166CrossRefPubMed De Sanctis V, Bossi P, Sanguineti G, Trippa F, Ferrari D, Bacigalupo A, Ripamonti CI, Buglione M, Pergolizzi S, Langendjik JA, Murphy B, Raber-Durlacher J, Russi EG, Lalla RV (2016) Mucositis in head and neck cancer patients treated with radiotherapy and systemic therapies: literature review and consensus statements. Crit Rev Oncol Hematol 100:147–166CrossRefPubMed
13.
Zurück zum Zitat Deandrea S, Montanari M, Moja L, Apolone G (2008) Prevalence of undertreatment in cancer pain. A review of published literature. Ann Oncol 19:1985–1991CrossRefPubMedPubMedCentral Deandrea S, Montanari M, Moja L, Apolone G (2008) Prevalence of undertreatment in cancer pain. A review of published literature. Ann Oncol 19:1985–1991CrossRefPubMedPubMedCentral
14.
Zurück zum Zitat van den Beuken-van Everdingen MH, de Rijke JM, Kessels AG, Schouten HC, van Kleef M, Patijn J (2007) Prevalence of pain in patients with cancer: a systematic review of the past 40 years. Ann Oncol 18:1437–1449CrossRef van den Beuken-van Everdingen MH, de Rijke JM, Kessels AG, Schouten HC, van Kleef M, Patijn J (2007) Prevalence of pain in patients with cancer: a systematic review of the past 40 years. Ann Oncol 18:1437–1449CrossRef
15.
Zurück zum Zitat van der Peet EH, van den Beuken-van Everdingen MH, Patijn J, Schouten HC, van Kleef M, Courtens AM (2009) Randomized clinical trial of an intensive nursing-based pain education program for cancer outpatients suffering from pain. Support Care Cancer 17:1089–1099CrossRefPubMed van der Peet EH, van den Beuken-van Everdingen MH, Patijn J, Schouten HC, van Kleef M, Courtens AM (2009) Randomized clinical trial of an intensive nursing-based pain education program for cancer outpatients suffering from pain. Support Care Cancer 17:1089–1099CrossRefPubMed
16.
Zurück zum Zitat Epstein JB, Wilkie DJ, Fischer DJ, Kim YO, Villines D (2009) Neuropathic and nociceptive pain in head and neck cancer patients receiving radiation therapy. Head Neck Oncol 1:26CrossRefPubMedPubMedCentral Epstein JB, Wilkie DJ, Fischer DJ, Kim YO, Villines D (2009) Neuropathic and nociceptive pain in head and neck cancer patients receiving radiation therapy. Head Neck Oncol 1:26CrossRefPubMedPubMedCentral
17.
Zurück zum Zitat Ferlito A, Shaha AR, Silver CE, Rinaldo A, Mondin V (2001) Incidence and sites of distant metastases from head and neck cancer. ORL J Otorhinolaryngol Relat Spec 63:202–207CrossRefPubMed Ferlito A, Shaha AR, Silver CE, Rinaldo A, Mondin V (2001) Incidence and sites of distant metastases from head and neck cancer. ORL J Otorhinolaryngol Relat Spec 63:202–207CrossRefPubMed
18.
Zurück zum Zitat Greco MT, Roberto A, Corli O, Deandrea S, Bandieri E, Cavuto S, Apolone G (2014) Quality of cancer pain management: an update of a systematic review of undertreatment of patients with cancer. J Clin Oncol 32:4149–4154CrossRefPubMed Greco MT, Roberto A, Corli O, Deandrea S, Bandieri E, Cavuto S, Apolone G (2014) Quality of cancer pain management: an update of a systematic review of undertreatment of patients with cancer. J Clin Oncol 32:4149–4154CrossRefPubMed
19.
Zurück zum Zitat Grond S, Zech D, Diefenbach C, Radbruch L, Lehmann KA (1996) Assessment of cancer pain: a prospective evaluation in 2266 cancer patients referred to a pain service. Pain 64:107–114CrossRefPubMed Grond S, Zech D, Diefenbach C, Radbruch L, Lehmann KA (1996) Assessment of cancer pain: a prospective evaluation in 2266 cancer patients referred to a pain service. Pain 64:107–114CrossRefPubMed
20.
Zurück zum Zitat Huang CH, Chu ST, Ger LP, Hou YY, Sun CP (2007) Clinicopathologic evaluation of prognostic factors for squamous cell carcinoma of the buccal mucosa. J Chin Med Assoc 70:164–170CrossRefPubMed Huang CH, Chu ST, Ger LP, Hou YY, Sun CP (2007) Clinicopathologic evaluation of prognostic factors for squamous cell carcinoma of the buccal mucosa. J Chin Med Assoc 70:164–170CrossRefPubMed
21.
Zurück zum Zitat Jadad AR, Browman GP (1995) The WHO analgesic ladder for cancer pain management. Stepping up the quality of its evaluation. Jama 274:1870–1873CrossRefPubMed Jadad AR, Browman GP (1995) The WHO analgesic ladder for cancer pain management. Stepping up the quality of its evaluation. Jama 274:1870–1873CrossRefPubMed
22.
Zurück zum Zitat Keefe FJ, Manuel G, Brantley A, Crisson J (1986) Pain in the head and neck cancer patient: changes over treatment. Head Neck Surg 8:169–176CrossRefPubMed Keefe FJ, Manuel G, Brantley A, Crisson J (1986) Pain in the head and neck cancer patient: changes over treatment. Head Neck Surg 8:169–176CrossRefPubMed
23.
Zurück zum Zitat Liao CM, Lin CM (2015) Geographical inequalities in alcohol-related mortality rates in Taiwan due to socio-demographic differences. Alcohol Alcohol 50:558–564CrossRefPubMed Liao CM, Lin CM (2015) Geographical inequalities in alcohol-related mortality rates in Taiwan due to socio-demographic differences. Alcohol Alcohol 50:558–564CrossRefPubMed
24.
Zurück zum Zitat Licitra L, Keilholz U, Tahara M, Lin JC, Chomette P, Ceruse P, Harrington K, Mesia R (2016) Evaluation of the benefit and use of multidisciplinary teams in the treatment of head and neck cancer. Oral Oncol 59:73–79CrossRefPubMed Licitra L, Keilholz U, Tahara M, Lin JC, Chomette P, Ceruse P, Harrington K, Mesia R (2016) Evaluation of the benefit and use of multidisciplinary teams in the treatment of head and neck cancer. Oral Oncol 59:73–79CrossRefPubMed
25.
Zurück zum Zitat Lo WL, Kao SY, Chi LY, Wong YK, Chang RC (2003) Outcomes of oral squamous cell carcinoma in Taiwan after surgical therapy: factors affecting survival. J Oral Maxillofac Surg 61:751–758CrossRefPubMed Lo WL, Kao SY, Chi LY, Wong YK, Chang RC (2003) Outcomes of oral squamous cell carcinoma in Taiwan after surgical therapy: factors affecting survival. J Oral Maxillofac Surg 61:751–758CrossRefPubMed
26.
Zurück zum Zitat Macfarlane TV, Wirth T, Ranasinghe S, Ah-See KW, Renny N, Hurman D (2012) Head and neck cancer pain: systematic review of prevalence and associated factors. J Oral Maxillofac Res 3:e1CrossRefPubMedPubMedCentral Macfarlane TV, Wirth T, Ranasinghe S, Ah-See KW, Renny N, Hurman D (2012) Head and neck cancer pain: systematic review of prevalence and associated factors. J Oral Maxillofac Res 3:e1CrossRefPubMedPubMedCentral
27.
Zurück zum Zitat Mantyh PW (2006) Cancer pain and its impact on diagnosis, survival and quality of life. Nat Rev Neurosci 7:797–809CrossRefPubMed Mantyh PW (2006) Cancer pain and its impact on diagnosis, survival and quality of life. Nat Rev Neurosci 7:797–809CrossRefPubMed
28.
Zurück zum Zitat Marquie L, Raufaste E, Lauque D, Marine C, Ecoiffier M, Sorum P (2003) Pain rating by patients and physicians: evidence of systematic pain miscalibration. Pain 102:289–296CrossRefPubMed Marquie L, Raufaste E, Lauque D, Marine C, Ecoiffier M, Sorum P (2003) Pain rating by patients and physicians: evidence of systematic pain miscalibration. Pain 102:289–296CrossRefPubMed
29.
Zurück zum Zitat McCaul LK (2012) Oral and dental management for head and neck cancer patients treated by chemotherapy and radiotherapy. Dental Update 39:135–138 140CrossRefPubMed McCaul LK (2012) Oral and dental management for head and neck cancer patients treated by chemotherapy and radiotherapy. Dental Update 39:135–138 140CrossRefPubMed
30.
Zurück zum Zitat Merino OR, Lindberg RD, Fletcher GH (1977) An analysis of distant metastases from squamous cell carcinoma of the upper respiratory and digestive tracts. Cancer 40:145–151CrossRefPubMed Merino OR, Lindberg RD, Fletcher GH (1977) An analysis of distant metastases from squamous cell carcinoma of the upper respiratory and digestive tracts. Cancer 40:145–151CrossRefPubMed
31.
Zurück zum Zitat Ohrn KE, Sjoden PO, Wahlin YB, Elf M (2001) Oral health and quality of life among patients with head and neck cancer or haematological malignancies. Support Care Cancer 9:528–538CrossRefPubMed Ohrn KE, Sjoden PO, Wahlin YB, Elf M (2001) Oral health and quality of life among patients with head and neck cancer or haematological malignancies. Support Care Cancer 9:528–538CrossRefPubMed
32.
Zurück zum Zitat Rose-Ped AM, Bellm LA, Epstein JB, Trotti A, Gwede C, Fuchs HJ (2002) Complications of radiation therapy for head and neck cancers. The patient’s perspective. Cancer Nurs 25:461–467 quiz 468-469CrossRefPubMed Rose-Ped AM, Bellm LA, Epstein JB, Trotti A, Gwede C, Fuchs HJ (2002) Complications of radiation therapy for head and neck cancers. The patient’s perspective. Cancer Nurs 25:461–467 quiz 468-469CrossRefPubMed
33.
Zurück zum Zitat Saxena A, Gnanasekaran N, Andley M (1995) An epidemiological study of prevalence of pain in head & neck cancers. Indian J Med Res 102:28–33PubMed Saxena A, Gnanasekaran N, Andley M (1995) An epidemiological study of prevalence of pain in head & neck cancers. Indian J Med Res 102:28–33PubMed
34.
Zurück zum Zitat Sroussi HY, Epstein JB, Bensadoun RJ, Saunders DP, Lalla RV, Migliorati CA, Heaivilin N, Zumsteg ZS (2017) Common oral complications of head and neck cancer radiation therapy: mucositis, infections, saliva change, fibrosis, sensory dysfunctions, dental caries, periodontal disease, and osteoradionecrosis. Cancer Med 6:2918–2931CrossRefPubMedPubMedCentral Sroussi HY, Epstein JB, Bensadoun RJ, Saunders DP, Lalla RV, Migliorati CA, Heaivilin N, Zumsteg ZS (2017) Common oral complications of head and neck cancer radiation therapy: mucositis, infections, saliva change, fibrosis, sensory dysfunctions, dental caries, periodontal disease, and osteoradionecrosis. Cancer Med 6:2918–2931CrossRefPubMedPubMedCentral
35.
Zurück zum Zitat Sutherland JE, Wesley RM, Cole PM, Nesvacil LJ, Daly ML, Gepner GJ (1988) Differences and similarities between patient and physician perceptions of patient pain. Fam Med 20:343–346PubMed Sutherland JE, Wesley RM, Cole PM, Nesvacil LJ, Daly ML, Gepner GJ (1988) Differences and similarities between patient and physician perceptions of patient pain. Fam Med 20:343–346PubMed
36.
Zurück zum Zitat Vokes EE, Weichselbaum RR, Lippman SM, Hong WK (1993) Head and neck cancer. N Engl J Med 328:184–194CrossRefPubMed Vokes EE, Weichselbaum RR, Lippman SM, Hong WK (1993) Head and neck cancer. N Engl J Med 328:184–194CrossRefPubMed
37.
Zurück zum Zitat Wagner CL, Baggerly C, McDonnell S, Baggerly KA, French CB, Baggerly L, Hamilton SA, Hollis BW (2016) Post-hoc analysis of vitamin D status and reduced risk of preterm birth in two vitamin D pregnancy cohorts compared with South Carolina March of Dimes 2009–2011 rates. J Steroid Biochem Mol Biol 155:245–251CrossRefPubMed Wagner CL, Baggerly C, McDonnell S, Baggerly KA, French CB, Baggerly L, Hamilton SA, Hollis BW (2016) Post-hoc analysis of vitamin D status and reduced risk of preterm birth in two vitamin D pregnancy cohorts compared with South Carolina March of Dimes 2009–2011 rates. J Steroid Biochem Mol Biol 155:245–251CrossRefPubMed
38.
Zurück zum Zitat Williams JE, Peacock J, Gubbay AN, Kuo PY, Ellard R, Gupta R, Riley J, Sauzet O, Raftery J, Yao G, Ross J (2015) Routine screening for pain combined with a pain treatment protocol in head and neck cancer: a randomised controlled trial. Br J Anaesth 115:621–628CrossRefPubMed Williams JE, Peacock J, Gubbay AN, Kuo PY, Ellard R, Gupta R, Riley J, Sauzet O, Raftery J, Yao G, Ross J (2015) Routine screening for pain combined with a pain treatment protocol in head and neck cancer: a randomised controlled trial. Br J Anaesth 115:621–628CrossRefPubMed
39.
Zurück zum Zitat de Wit R, van Dam F, Loonstra S, Zandbelt L, van Buuren A, van der Heijden K, Leenhouts G, Duivenvoorden H, Huijer Abu-Saad H (2001) Improving the quality of pain treatment by a tailored pain education programme for cancer patients in chronic pain. Eur J Pain 5:241–256CrossRefPubMed de Wit R, van Dam F, Loonstra S, Zandbelt L, van Buuren A, van der Heijden K, Leenhouts G, Duivenvoorden H, Huijer Abu-Saad H (2001) Improving the quality of pain treatment by a tailored pain education programme for cancer patients in chronic pain. Eur J Pain 5:241–256CrossRefPubMed
40.
Zurück zum Zitat Wong ES, Wang BC, Garrison LP, Alfonso-Cristancho R, Flum DR, Arterburn DE, Sullivan SD (2011) Examining the BMI–mortality relationship using fractional polynomials. BMC Med Res Methodol 11:175CrossRefPubMedPubMedCentral Wong ES, Wang BC, Garrison LP, Alfonso-Cristancho R, Flum DR, Arterburn DE, Sullivan SD (2011) Examining the BMI–mortality relationship using fractional polynomials. BMC Med Res Methodol 11:175CrossRefPubMedPubMedCentral
41.
Zurück zum Zitat Zelman DC, Dukes E, Brandenburg N, Bostrom A, Gore M (2005) Identification of cut-points for mild, moderate and severe pain due to diabetic peripheral neuropathy. Pain 115:29–36CrossRefPubMed Zelman DC, Dukes E, Brandenburg N, Bostrom A, Gore M (2005) Identification of cut-points for mild, moderate and severe pain due to diabetic peripheral neuropathy. Pain 115:29–36CrossRefPubMed
Metadaten
Titel
Patients with head and neck cancer may need more intensive pain management to maintain daily functioning: a multi-center study
verfasst von
Shih-Feng Cho
Kun-Ming Rau
Yu-Yun Shao
Chia-Jui Yen
Ming-Fang Wu
Jen-Shi Chen
Cheng-Shyong Chang
Su-Peng Yeh
Tzeon-Jye Chiou
Ruey-Kuen Hsieh
Ming-Yang Lee
Yung-Chuan Sung
Kuan-Der Lee
Pang-Yu Lai
Ming-Sun Yu
Wen-Li Hwang
Ta-Chih Liu
Publikationsdatum
15.08.2018
Verlag
Springer Berlin Heidelberg
Erschienen in
Supportive Care in Cancer / Ausgabe 5/2019
Print ISSN: 0941-4355
Elektronische ISSN: 1433-7339
DOI
https://doi.org/10.1007/s00520-018-4404-x

Weitere Artikel der Ausgabe 5/2019

Supportive Care in Cancer 5/2019 Zur Ausgabe

Update Onkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.