nach oben

Erschienen in:

01.05.2012 | Original Article

Pattern of joint damage in persons with knee osteoarthritis and concomitant ACL tears

verfasst von: Verena Stein, Ling Li, Grace Lo, Ali Guermazi, Yuqing Zhang, C. Kent Kwoh, Charles B. Eaton, David J. Hunter

Erschienen in: Rheumatology International | Ausgabe 5/2012

Einloggen, um Zugang zu erhalten

Abstract

Anterior cruciate ligament (ACL) tears are known to be a risk factor for incident knee osteoarthritis (OA). At the present time, it is unknown whether an incidental ACL tear in those with established knee OA alters the pattern of synovial joint damage. Therefore, our aim was to assess whether ACL tears in persons with knee OA are associated with specific patterns of cartilage loss, meniscal degeneration, and bone marrow lesion (BML) location. We included 160 participants from the progression subcohort of the Osteoarthritis Initiative (OAI) Study, an ongoing 4-year, multicenter study, focusing on knee OA. Regional cartilage morphometry measures including cartilage volume (mm³), denuded area, normalized cartilage volume, bone surface area, as well as location of meniscal pathology and BMLs in index knees on the same side were compared between those with and without ACL tears. Of the 160 subjects (51% women, age 62.1 (±9.9), BMI 30.3 (±4.7) kg/m²), 14.4% had an ACL tear. After adjusting for age, BMI and gender participants with ACL tears had significantly greater cartilage volume in the posterior lateral femur (P = 0.04) and the central medial tibia (0.001) compared to those without ACL tears. Normalized cartilage volume was not different between those with and without ACL tears. In addition, individuals with ACL tears had significantly larger bone surface areas in the medial tibia (P = 0,006), the central medial tibia (P = 0.008), the posterior lateral femur (P = 0.004), and the posterior medial femur (P = 0.04). Furthermore, participants with ACL tears showed significantly more meniscal derangement in the lateral posterior horn (P = 0.019) and significantly more BMLs in the lateral femur (P = 0.0025). We found clear evidence of predominant lateral tibiofemoral involvement, with OA-associated findings on MRI, including increased denuded area and bone surface area, BMLs, and meniscal derangement in knees of individuals with ACL tears compared to those without.

Prevalence of disabilities and associated health conditions among adults–United States (1999) MMWR Morb Mortal Wkly Rep 2001 50(7):120–125

Felson DT, McAlindon TE, Anderson JJ, Naimark A, Weissman BW, Aliabadi P et al (1997) Defining radiographic osteoarthritis for the whole knee. Osteoarthr Cartil 5(4):241–250PubMedCrossRef

Mackenzie R, Palmer CR, Lomas DJ, Dixon AK (1996) Magnetic resonance imaging of the knee: diagnostic performance studies. Clin Radiol 51(4):251–257PubMedCrossRef

Cotten A, Delfaut E, Demondion X, Lapegue F, Boukhelifa M, Boutry N et al (2000) MR imaging of the knee at 0.2 and 1.5 T: correlation with surgery. AJR Am J Roentgenol 174(4):1093–1097PubMed

Vincken PW, ter Braak BP, van Erkell AR, de Rooy TP, Mallens WM, Post W et al (2002) Effectiveness of MR imaging in selection of patients for arthroscopy of the knee. Radiology 223(3):739–746PubMedCrossRef

Eckstein F, Glaser C (2004) Measuring cartilage morphology with quantitative magnetic resonance imaging. Semin Musculoskelet Radiol 8(4):329–353PubMedCrossRef

Peterfy CG, Guermazi A, Zaim S, Tirman PF, Miaux Y, White D et al (2004) Whole-organ magnetic resonance imaging score (WORMS) of the knee in osteoarthritis. Osteoarthr Cartil 12(3):177–190PubMedCrossRef

Felson DT, Anderson JJ, Naimark A, Kannel W, Meenan RF (1989) The prevalence of chondrocalcinosis in the elderly and its association with knee osteoarthritis: the Framingham study. J Rheumatol 16(9):1241–1245PubMed

Davis MA, Ettinger WH, Neuhaus JM, Cho SA, Hauck WW (1989) The association of knee injury and obesity with unilateral and bilateral osteoarthritis of the knee. Am J Epidemiol 130(2):278–288PubMed

10.

Wilder FV, Hall BJ, Barrett JP Jr, Lemrow NB (2002) History of acute knee injury and osteoarthritis of the knee: a prospective epidemiological assessment. The clearwater osteoarthritis study. Osteoarthr Cartil 10(8):611–616PubMedCrossRef

11.

Lohmander LS, Englund PM, Dahl LL, Roos EM (2007) The long-term consequence of anterior cruciate ligament and meniscus injuries: osteoarthritis. Am J Sports Med 35(10):1756–1769PubMedCrossRef

12.

Arendt EA, Agel J, Dick R (1999) Anterior cruciate ligament injury patterns among collegiate men and women. J Athl Train 34(2):86–92PubMed

13.

Boden BP, Dean GS, Feagin JA Jr, Garrett WE Jr (2000) Mechanisms of anterior cruciate ligament injury. Orthopedics 23(6):573–578PubMed

14.

Roos H, Adalberth T, Dahlberg L, Lohmander LS (1995) Osteoarthritis of the knee after injury to the anterior cruciate ligament or meniscus: the influence of time and age. Osteoarthr Cartil 3(4):261–267PubMedCrossRef

15.

Myklebust R, Mayhew TM (1998) Further evidence of species variation in mechanisms of epithelial cell loss in mammalian small intestine: ultrastructural studies on the reindeer (Rangifer tarandus) and seal (Phoca groenlandica). Cell Tissue Res 291(3):513–523PubMedCrossRef

16.

Daniel DM, Stone ML, Dobson BE, Fithian DC, Rossman DJ, Kaufman KR (1994) Fate of the ACL-injured patient. A prospective outcome study. Am J Sports Med 22(5):632–644PubMedCrossRef

17.

Kannus P, Jarvinen M (1989) Posttraumatic anterior cruciate ligament insufficiency as a cause of osteoarthritis in a knee joint. Clin Rheumatol 8(2):251–260PubMedCrossRef

18.

Lohmander LS, Ostenberg A, Englund M, Roos H (2004) High prevalence of knee osteoarthritis, pain, and functional limitations in female soccer players twelve years after anterior cruciate ligament injury. Arthritis Rheum 50(10):3145–3152PubMedCrossRef

19.

Maletius W, Messner K (1999) Eighteen- to twenty-four-year follow-up after complete rupture of the anterior cruciate ligament. Am J Sports Med 27(6):711–717PubMed

20.

von Porat A, Roos EM, Roos H (2004) High prevalence of osteoarthritis 14 years after an anterior cruciate ligament tear in male soccer players: a study of radiographic and patient relevant outcomes. Ann Rheum Dis 63(3):269–273CrossRef

21.

McDaniel WJ Jr, Dameron TB Jr (1983) The untreated anterior cruciate ligament rupture. Clin Orthop Relat Res 172:158–163PubMed

22.

Clatworthy M, Amendola A (1999) The anterior cruciate ligament and arthritis. Clin Sports Med 18(1):173–198 viiPubMedCrossRef

23.

Hill CL, Seo GS, Gale D, Totterman S, Gale ME, Felson DT (2005) Cruciate ligament integrity in osteoarthritis of the knee. Arthritis Rheum 52(3):794–799PubMedCrossRef

24.

Maffulli N, Binfield PM, King JB (2003) Articular cartilage lesions in the symptomatic anterior cruciate ligament-deficient knee. Arthroscopy 19(7):685–690PubMedCrossRef

25.

Costa-Paz M, Muscolo DL, Ayerza M, Makino A, Aponte-Tinao L (2001) Magnetic resonance imaging follow-up study of bone bruises associated with anterior cruciate ligament ruptures. Arthroscopy 17(5):445–449PubMedCrossRef

26.

Scarvell JM, Smith PN, Refshauge KM, Galloway HR, Woods KR (2005) Association between abnormal kinematics and degenerative change in knees of people with chronic anterior cruciate ligament deficiency: a magnetic resonance imaging study. Aust J Physiother 51(4):233–240PubMedCrossRef

27.

Scarvell JM, Smith PN, Refshauge KM, Galloway HR, Woods KR (2004) Comparison of kinematic analysis by mapping tibiofemoral contact with movement of the femoral condylar centres in healthy and anterior cruciate ligament injured knees. J Orthop Res 22(5):955–962PubMedCrossRef

28.

Hunter DJ, Niu J, Zhang Y, Totterman S, Tamez J, Dabrowski C et al. (2009) Change in cartilage morphometry: a sample of the progression cohort of the osteoarthritis initiative. Ann Rheum Dis 68(3):349–356

29.

Peterfy C, Li J, Zaim S, Duryea J, Lynch J, Miaux Y et al (2003) Comparison of fixed-flexion positioning with fluoroscopic semi-flexed positioning for quantifying radiographic joint-space width in the knee: test-retest reproducibility. Skeletal Radiol 32(3):128–132PubMedCrossRef

30.

Kellgren JH, Lawrence JS (1957) Radiological assessment of osteo-arthrosis. Ann Rheum Dis 16(4):494–502PubMedCrossRef

31.

Hunter DJ, Lo GH, Gale D, Grainger AJ, Guermazi A, Conaghan PG (2008) The reliability of a new scoring system for knee osteoarthritis MRI and the validity of bone marrow lesion assessment: BLOKS (Boston leeds osteoarthritis knee score). Ann Rheum Dis 67(2):206–211PubMedCrossRef

32.

Frobell RB, Lohmander LS, Roos HP (2007) Acute rotational trauma to the knee: poor agreement between clinical assessment and magnetic resonance imaging findings. Scand J Med Sci Sports 17(2):109–114PubMed

33.

Noyes FR, Bassett RW, Grood ES, Butler DL (1980) Arthroscopy in acute traumatic hemarthrosis of the knee. Incidence of anterior cruciate tears and other injuries. J Bone Joint Surg Am 62(5):687–695, 757

34.

Indelicato PA, Bittar ES (1985) A perspective of lesions associated with ACL insufficiency of the knee. A review of 100 cases. Clin Orthop Relat Res 198:77–80PubMed

35.

Escalas F, Curell R (1994) Occult posttraumatic bone injury. Knee Surg Sports Traumatol Arthrosc 2(3):147–149PubMedCrossRef

36.

Even-Sapir E, Arbel R, Lerman H, Flusser G, Livshitz G, Halperin N (2002) Bone injury associated with anterior cruciate ligament and meniscal tears: assessment with bone single photon emission computed tomography. Invest Radiol 37(9):521–527PubMedCrossRef

37.

Lahm A, Erggelet C, Steinwachs M, Reichelt A (1998) Articular and osseous lesions in recent ligament tears: arthroscopic changes compared with magnetic resonance imaging findings. Arthroscopy 14(6):597–604PubMedCrossRef

38.

Swaerd P, Kostogiannis I, Neuman P, Boegard T, Roos H (2010) Differences in radiological characteristics between post-traumatic and non-traumatic knee osteoarthritis. Scand J Med Sci Sports 20(5):731–739

39.

Tandogan RN, Taser O, Kayaalp A, Taskiran E, Pinar H, Alparslan B et al (2004) Analysis of meniscal and chondral lesions accompanying anterior cruciate ligament tears: relationship with age, time from injury, and level of sport. Knee Surg Sports Traumatol Arthrosc 12(4):262–270PubMedCrossRef

40.

Scarvell JM, Smith PN, Refshauge KM, Galloway H, Woods K (2005) Comparison of kinematics in the healthy and ACL injured knee using MRI. J Biomech 38(2):255–262PubMedCrossRef

41.

Nishimori M, Deie M, Adachi N, Kanaya A, Nakamae A, Motoyama M et al (2008) Articular cartilage injury of the posterior lateral tibial plateau associated with acute anterior cruciate ligament injury. Knee Surg Sports Traumatol Arthrosc 16(3):270–274PubMedCrossRef

42.

Cipolla M, Scala A, Gianni E, Puddu G (1995) Different patterns of meniscal tears in acute anterior cruciate ligament (ACL) ruptures and in chronic ACL-deficient knees. Classification, staging and timing of treatment. Knee Surg Sports Traumatol Arthrosc 3(3):130–134PubMedCrossRef

43.

Nikolic DK (1998) Lateral meniscal tears and their evolution in acute injuries of the anterior cruciate ligament of the knee. Arthroscopic analysis. Knee Surg Sports Traumatol Arthrosc 6(1):26–30PubMedCrossRef

44.

Smith JP III, Barrett GR (2001) Medial and lateral meniscal tear patterns in anterior cruciate ligament-deficient knees. A prospective analysis of 575 tears. Am J Sports Med 29(4):415–419PubMed

45.

Smith GN, Mickler EA, Albrecht ME, Myers SL, Brandt KD (2002) Severity of medial meniscus damage in the canine knee after anterior cruciate ligament transection. Osteoarthr Cartil 10(4):321–326PubMedCrossRef

46.

Fowler PJ (1994) Bone injuries associated with anterior cruciate ligament disruption. Arthroscopy 10(4):453–460PubMedCrossRef

47.

Rosen MA, Jackson DW, Berger PE (1991) Occult osseous lesions documented by magnetic resonance imaging associated with anterior cruciate ligament ruptures. Arthroscopy 7(1):45–51PubMedCrossRef

48.

Speer KP, Spritzer CE, Bassett FH III, Feagin JA Jr, Garrett WE Jr (1992) Osseous injury associated with acute tears of the anterior cruciate ligament. Am J Sports Med 20(4):382–389PubMedCrossRef

49.

Spindler KP, Schils JP, Bergfeld JA, Andrish JT, Weiker GG, Anderson TE et al (1993) Prospective study of osseous, articular, and meniscal lesions in recent anterior cruciate ligament tears by magnetic resonance imaging and arthroscopy. Am J Sports Med 21(4):551–557PubMedCrossRef

50.

Stein LN, Fischer DA, Fritts HM, Quick DC (1995) Occult osseous lesions associated with anterior cruciate ligament tears. Clin Orthop Relat Res 313:187–193PubMed

51.

Johnson DL, Urban WP Jr, Caborn DN, Vanarthos WJ, Carlson CS (1998) Articular cartilage changes seen with magnetic resonance imaging-detected bone bruises associated with acute anterior cruciate ligament rupture. Am J Sports Med 26(3):409–414PubMed

52.

Murphy BJ, Smith RL, Uribe JW, Janecki CJ, Hechtman KS, Mangasarian RA (1992) Bone signal abnormalities in the posterolateral tibia and lateral femoral condyle in complete tears of the anterior cruciate ligament: a specific sign? Radiology 182(1):221–224PubMed

53.

Viskontas DG, Giuffre BM, Duggal N, Graham D, Parker D, Coolican M (2008) Bone bruises associated with ACL rupture: correlation with injury mechanism. Am J Sports Med 36(5):927–933PubMedCrossRef

54.

Segawa H, Omori G, Koga Y (2001) Long-term results of non-operative treatment of anterior cruciate ligament injury. Knee 8(1):5–11PubMedCrossRef

55.

Gillquist J, Messner K (1999) Anterior cruciate ligament reconstruction and the long-term incidence of gonarthrosis. Sports Med 27(3):143–156PubMedCrossRef

56.

Myklebust G, Holm I, Maehlum S, Engebretsen L, Bahr R (2003) Clinical, functional, and radiologic outcome in team handball players 6 to 11 years after anterior cruciate ligament injury: a follow-up study. Am J Sports Med 31(6):981–989PubMed

57.

Jones HP, Appleyard RC, Mahajan S, Murrell GA (2003) Meniscal and chondral loss in the anterior cruciate ligament injured knee. Sports Med 33(14):1075–1089PubMedCrossRef

58.

Amin S, Guermazi A, Lavalley MP, Niu J, Clancy M, Hunter DJ et al (2008) Complete anterior cruciate ligament tear and the risk for cartilage loss and progression of symptoms in men and women with knee osteoarthritis. Osteoarthr Cartil 16(8):897–902PubMedCrossRef

59.

Link TM, Steinbach LS, Ghosh S, Ries M, Lu Y, Lane N et al (2003) Osteoarthritis: MR imaging findings in different stages of disease and correlation with clinical findings. Radiology 226(2):373–381PubMedCrossRef

60.

Chan WP, Lang P, Stevens MP, Sack K, Majumdar S, Stoller DW et al (1991) Osteoarthritis of the knee: comparison of radiography, CT, and MR imaging to assess extent and severity. AJR Am J Roentgenol 157(4):799–806PubMed

61.

Lee JK, Yao L, Phelps CT, Wirth CR, Czajka J, Lozman J (1988) Anterior cruciate ligament tears: MR imaging compared with arthroscopy and clinical tests. Radiology 166(3):861–864PubMed

62.

Rose NE, Gold SM (1996) A comparison of accuracy between clinical examination and magnetic resonance imaging in the diagnosis of meniscal and anterior cruciate ligament tears. Arthroscopy 12(4):398–405PubMedCrossRef

63.

Glashow JL, Katz R, Schneider M, Scott WN (1989) Double-blind assessment of the value of magnetic resonance imaging in the diagnosis of anterior cruciate and meniscal lesions. J Bone Joint Surg Am 71(1):113–119PubMed

64.

Polly DW Jr, Callaghan JJ, Sikes RA, McCabe JM, McMahon K, Savory CG (1988) The accuracy of selective magnetic resonance imaging compared with the findings of arthroscopy of the knee. J Bone Joint Surg Am 70(2):192–198PubMed

Titel: Pattern of joint damage in persons with knee osteoarthritis and concomitant ACL tears
verfasst von: Verena Stein
Ling Li
Grace Lo
Ali Guermazi
Yuqing Zhang
C. Kent Kwoh
Charles B. Eaton
David J. Hunter
Publikationsdatum: 01.05.2012
Verlag: Springer-Verlag
Erschienen in: Rheumatology International / Ausgabe 5/2012
Print ISSN: 0172-8172
Elektronische ISSN: 1437-160X
DOI: https://doi.org/10.1007/s00296-010-1749-y

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

^{Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag}

Kostenlos registrieren

Neu im Fachgebiet Innere Medizin

19.04.2024 | Vorhofflimmern | Nachrichten

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen

Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

Pattern of joint damage in persons with knee osteoarthritis and concomitant ACL tears

Abstract

Leitlinien kompakt für die Innere Medizin

Neu im Fachgebiet Innere Medizin

Parodontalbehandlung verbessert Prognose bei Katheterablation

Prostatakarzinom: EU initiiert neues Screeningkonzept

Blasenkarzinom – Biomarker statt Zytologie?

Antihypertensiva schützen auch alte Menschen noch vor Demenz

Update Innere Medizin

Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

Abstract

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 5/2012

Therapeutic responses and prognosis in adult-onset Still’s disease

Clinical characteristics and electrodiagnostic features in patients with carpal tunnel syndrome, double crush syndrome, and cervical radiculopathy

Onycho-Pachydermatit with extensive bone marrow edema predominant in the metacarpals: a “forme fruste” of POPP?

Successful treatment with intravenous immunoglobulin of severe thrombocytopenia complicated in primary Sjögren’s syndrome

The effect of local corticosteroid injection on F-wave conduction velocity and sympathetic skin response in carpal tunnel syndrome

Long-term efficacy of anti-CD20 antibodies in refractory lupus nephritis

Leitlinien kompakt für die Innere Medizin

Neu im Fachgebiet Innere Medizin

Parodontalbehandlung verbessert Prognose bei Katheterablation

Prostatakarzinom: EU initiiert neues Screeningkonzept

Blasenkarzinom – Biomarker statt Zytologie?

Antihypertensiva schützen auch alte Menschen noch vor Demenz

Update Innere Medizin