Pediatric Nephrology

The association between serum uric acid levels and human disease has garnered intense interest over the last decade including chronic kidney disease. Animal studies have provided evidence for a potential mechanistic role of uric acid in promoting …

Although children and adolescents constitute a small proportion of the chronic kidney disease (CKD) population [ 1 ], the potential impact of kidney disease progression on growth and development represents a unique challenge to the health care …

Severe sepsis, a major source of morbidity and mortality in children, is increasing in prevalence over time [ 1 , 2 ]. Severe sepsis results in over 75,000 annual US pediatric hospitalizations with an estimated cost of nearly $5 billion [ 3 ]. The …

Children and adolescents with primary hypertension (HTN) can develop subclinical target organ damage (TOD), including left ventricular hypertrophy (LVH), increased carotid intima-media thickness (cIMT), and increased arterial stiffness, similar to …

Alport syndrome is a hereditary kidney disease which manifests with hematuria, proteinuria, progressive renal failure, sensorineural deafness, or typical ocular changes, which are caused by mutations in the COL4A5 , COL4A3 , or COL4A4 genes [ 1 ].