Introduction
Materials and methods
Setting and participants
Data collection
Outcome measures
Statistical analyses
Ethical aspects
Results
Characteristics of the study population
Characteristic | Study population N = 2933 | Data missing n (%) |
---|---|---|
Age (years), mean ± SD | 64.0 ± 10.5 | 2 (0.1) |
BMI (kg/m²), mean ± SD | 26.9 ± 4.1 | 99 (3.4) |
Parity, median (IQR) | 2 (1) | 47 (1.6) |
Current smoker, n (%) | 255 (8.7) | 11 (0.4) |
Diabetes, n (%) | 283 (9.6) | 0 |
Prior hysterectomy, n (%) | 981 (33.4) | 0 |
Prior POP surgery, n (%) | 740 (25.2) | 0 |
Prior anti-incontinence surgery, n (%) | 170 (5.8) | 0 |
POP-Q point Ba ≥ 0, n (%) | 1859 (65.5) | 96 (3.3) |
POP-Q point C ≥ 0, n (%) | 1138 (40.6) | 130 (4.4) |
POP-Q point Bp ≥ 0, n (%) | 1259 (44.5) | 105 (3.6) |
PFDI-20 score, mean ± SD | 99.1 ± 49.9 | 5 (0.2) |
OAB medication, n (%) | 97 (3.3) | 0 |
Local or systemic estrogen therapy, n (%) | 2429 (82.9) | 4 (0.1) |
Type of surgery, n (%) | 0 | |
Native tissue repair | 2357 (80.4) | |
Vaginal mesh | 362 (12.3) | |
Abdominal mesh | 214 (7.3) |
Prevalence of OAB symptoms at baseline
Repair group | Symptom present | Urinary frequency | Urgency incontinence | Either symptom | ||||||
---|---|---|---|---|---|---|---|---|---|---|
Baseline | 6 months | 24 months | Baseline | 6 months | 24 months | Baseline | 6 months | 24 months | ||
All | Yes; any degree of bother | 1890 (66.9) | 828 (33.7) | 910 (39.6) | 1759 (61.8) | 1186 (48.2) | 1158 (50.7) | 2346 (82.3) | 1422 (57.9) | 1451 (63.4) |
Yes, bothersome symptom | 875 (31.0) | 204 (8.3) | 258 (11.2) | 744 (26.2) | 257 (10.4) | 326 (14.3) | 1135 (40.4) | 331 (13.6) | 423 (18.6) | |
No | 935 (33.1) | 1630 (66.3) | 1390 (60.4) | 1086 (38.2) | 1274 (51.8) | 1124 (49.3) | 504 (17.7) | 1035 (42.1) | 838 (36.6) | |
Anterior/Apical | Yes; any degree of bother | 1568 (69.8) | 650 (33.0) | 733 (39.8) | 1462 (64.6) | 958 (48.7) | 947 (51.9) | 1929 (85.1) | 1136 (57.8) | 1175 (64.1) |
Yes, bothersome symptom | 735 (32.7) | 159 (8.1) | 198 (10.8) | 618 (27.3) | 202 (10.3) | 261 (14.3) | 945 (42.3) | 255 (13.1) | 333 (18.3) | |
No | 678 (30.2) | 1321 (67.0) | 1108 (60.2) | 801 (35.4) | 1011 (51.3) | 878 (48.1) | 338 (14.9) | 831 (42.2) | 657 (35.9) | |
Posterior | Yes; any degree of bother | 297 (54.6) | 165 (35.8) | 164 (38.1) | 273 (49.9) | 213 (45.7) | 197 (45.8) | 387 (70.6) | 268 (57.8) | 260 (60.5) |
Yes, bothersome symptom | 129 (23.7) | 43 (9.3) | 57 (13.2) | 114 (20.8) | 51 (10.9) | 60 (14.0) | 175 (32.4) | 72 (15.7) | 84 (19.7) | |
No | 247 (45.4) | 296 (64.2) | 267 (61.9) | 274 (50.1) | 253 (54.3) | 233 (54.2) | 161 (29.4) | 196 (42.2) | 170 (39.5) |