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Erschienen in: Medical Oncology 4/2017

01.04.2017 | Original Paper

Percutaneous needle biopsy of mediastinal masses under C-arm conebeam CT guidance: diagnostic performance and safety

verfasst von: Chiara Floridi, Alfonso Reginelli, Raffaella Capasso, Enrico Fumarola, Filippo Pesapane, Antonio Barile, Marcello Zappia, Ferdinando Caranci, Luca Brunese

Erschienen in: Medical Oncology | Ausgabe 4/2017

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Abstract

The aim of this study is to evaluate the feasibility of percutaneous needle biopsy of mediastinal masses under conebeam computed tomography (CBCT) and “XperGuide” navigation guidance. From September 2013 to April 2016, 40 patients (25 men and 15 women; mean age 52.5 years; range 18.7–86.4 years) with 40 mediastinal masses underwent CBCT-/”XperGuide”-guided percutaneous needle biopsies. Technical success, sensibility, specificity, positive predictive value (ppv), negative predictive value (npv) and complications rate were evaluated. Technical success evaluated as the correct positioning of the needle inside the lesion was 100%. Based on histopathological diagnosis, 2 of 40 biopsies (5%) resulted a false negative. Diagnostic accuracy was 95%, sensitivity was 95%, specificity was 100%, ppv was 100%, and npv was 33%. The mean total procedure time was 32 min (range 15–60 min) revealing a reduction in time comparing the first group of 20 patients (mean time 45 min) with the last group of 20 patients (mean time 17 min). No major complications were recorded. Only three patients (7.5%) had mild pneumothorax as demonstrated by post-procedural CBCT, resolved spontaneously. CBCT/“XperGuide” navigation system is a new, safe and accurate technique that can be used as guidance for mediastinal mass biopsies. It also permits the use of CT machines for diagnostic examinations relieving them from interventional procedures burden.
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Metadaten
Titel
Percutaneous needle biopsy of mediastinal masses under C-arm conebeam CT guidance: diagnostic performance and safety
verfasst von
Chiara Floridi
Alfonso Reginelli
Raffaella Capasso
Enrico Fumarola
Filippo Pesapane
Antonio Barile
Marcello Zappia
Ferdinando Caranci
Luca Brunese
Publikationsdatum
01.04.2017
Verlag
Springer US
Erschienen in
Medical Oncology / Ausgabe 4/2017
Print ISSN: 1357-0560
Elektronische ISSN: 1559-131X
DOI
https://doi.org/10.1007/s12032-017-0911-8

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