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01.06.2014 | Ausgabe 6/2014

Surgical Endoscopy 6/2014

Performance of the forward-viewing linear echoendoscope for fine-needle aspiration of solid and cystic lesions throughout the gastrointestinal tract: a large single-center experience

Surgical Endoscopy > Ausgabe 6/2014
Alberto Larghi, Lorenzo Fuccio, Fabia Attili, Ester Diana Rossi, Matteo Napoleone, Domenico Galasso, Guido Fadda, Guido Costamagna



A newly developed forward-viewing linear echoendoscope (FV-EUS) has recently become available. To date, however, only scanty data on the performance of the FV-EUS scope for fine-needle aspiration (FNA) of lesions throughout the gastrointestinal (GI) tract are available. This study aimed to evaluate the technical performance of the FV-EUS scope for FNA of solid and cystic lesions located throughout the GI tract in a large cohort of patients referred to a tertiary care center.


All patients who underwent endoscopic ultrasound (EUS)-guided FNA using the FV-EUS scope between January 2007 and December 2008 were included in this retrospective study. The performance of the FV-EUS scope for FNA was evaluated.


During the study period, 285 patients with solid or cystic lesions throughout the GI tract underwent the procedure with the FV-EUS scope. A total of 300 FNAs were attempted, 6 (2 %) of which could not be performed. Of the 294 successful EUS-FNA procedures, 130 (44.2 %) were performed using a 22-gauge needle, 89 (30.3 %) using a 25-gauge needle, and 75 (25.5 %) using a 19-gauge needle. In all 67 cases of pancreatic cyst or dilated pancreatic duct, a specimen for cystic fluid analysis or cytologic examination could be obtained. Among the remaining 217 patients with solid lesion, a definitive diagnosis could be established for 211 patients (97.2 %). The FV-EUS scope had a sensitivity of 74.7 % (95 % confidence interval [CI] 68.1–80.6 %), a specificity of 100 % (95 % CI 89.9–100 %), a positive likelihood ratio of infinity, and a negative likelihood ratio of 0.251 (95 % CI 0.196–0.323).


The FV-EUS scope is highly effective for FNA of solid and cystic lesions throughout the GI tract. Prospective studies comparing the FV-EUS scope and a curved linear scope are needed.

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