Pericyte Plasticity in the Brain
- 01.06.2019
- Review
- Verfasst von
- Gabryella S. P. Santos
- Luiz A. V. Magno
- Marco A. Romano-Silva
- Akiva Mintz
- Alexander Birbrair
- Erschienen in
- Neuroscience Bulletin | Ausgabe 3/2019
Abstract
Cerebral pericytes are perivascular cells that stabilize blood vessels. Little is known about the plasticity of pericytes in the adult brain in vivo. Recently, using state-of-the-art technologies, including two-photon microscopy in combination with sophisticated Cre/loxP in vivo tracing techniques, a novel role of pericytes was revealed in vascular remodeling in the adult brain. Strikingly, after pericyte ablation, neighboring pericytes expand their processes and prevent vascular dilatation. This new knowledge provides insights into pericyte plasticity in the adult brain.
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- Titel
- Pericyte Plasticity in the Brain
- Verfasst von
-
Gabryella S. P. Santos
Luiz A. V. Magno
Marco A. Romano-Silva
Akiva Mintz
Alexander Birbrair
- Publikationsdatum
- 01.06.2019
- Verlag
- Springer Singapore
- Erschienen in
-
Neuroscience Bulletin / Ausgabe 3/2019
Print ISSN: 1673-7067
Elektronische ISSN: 1995-8218 - DOI
- https://doi.org/10.1007/s12264-018-0296-5
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