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Neuroscience Bulletin
Erschienen in:

01.06.2019 | Review

Pericyte Plasticity in the Brain

verfasst von: Gabryella S. P. Santos, Luiz A. V. Magno, Marco A. Romano-Silva, Akiva Mintz, Alexander Birbrair

Erschienen in: Neuroscience Bulletin | Ausgabe 3/2019

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Abstract

Cerebral pericytes are perivascular cells that stabilize blood vessels. Little is known about the plasticity of pericytes in the adult brain in vivo. Recently, using state-of-the-art technologies, including two-photon microscopy in combination with sophisticated Cre/loxP in vivo tracing techniques, a novel role of pericytes was revealed in vascular remodeling in the adult brain. Strikingly, after pericyte ablation, neighboring pericytes expand their processes and prevent vascular dilatation. This new knowledge provides insights into pericyte plasticity in the adult brain.
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Metadaten
Titel
Pericyte Plasticity in the Brain
verfasst von
Gabryella S. P. Santos
Luiz A. V. Magno
Marco A. Romano-Silva
Akiva Mintz
Alexander Birbrair
Publikationsdatum
01.06.2019
Verlag
Springer Singapore
Erschienen in
Neuroscience Bulletin / Ausgabe 3/2019
Print ISSN: 1673-7067
Elektronische ISSN: 1995-8218
DOI
https://doi.org/10.1007/s12264-018-0296-5

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