Skip to main content
Erschienen in: Surgical Endoscopy 4/2018

15.09.2017

Peritoneal dialysis catheter function and survival are not adversely affected by obesity regardless of the operative technique used

verfasst von: Monika A. Krezalek, Nicolas Bonamici, Kristine Kuchta, Brittany Lapin, JoAnn Carbray, Woody Denham, John Linn, Michael Ujiki, Stephen P. Haggerty

Erschienen in: Surgical Endoscopy | Ausgabe 4/2018

Einloggen, um Zugang zu erhalten

Abstract

Background

Obesity has been considered a relative contraindication to peritoneal dialysis (PD). Surprisingly, PD catheter dysfunction rates and longevity have not been studied in the growing obese ESRD population. The aim of this study was to determine the effect of patient weight on PD catheter survival in the three insertion technique categories of advanced laparoscopy (AL), basic laparoscopy (BL), and open.

Methods

We examine retrospectively collected data on 231 consecutive PD catheter insertions at the NorthShore University HealthSystem between 2004 and 2014. Three cohorts were created based on the catheter insertion technique: open, BL using selective adhesiolysis, and AL using rectus sheath tunnel, selective omentopexy, and adhesiolysis. Primary outcomes included catheter dysfunction and catheter dysfunction-free survival for each cohort by BMI: normal weight (18.5–24.9), overweight (25–29.9), obese (≥30). Nominal variables were compared using Chi-square test, continuous variables using ANOVA or Kruskal–Wallis tests, and catheter survival was assessed using the Kaplan–Meier method with log-rank test. Statistical significance was established at 0.05.

Results

For the three BMI categories, there were no statistically significant differences in patient demographics. There were no statistically significant differences in catheter dysfunction or peri-operative complications by BMI category among all patients. This was also true in the AL cohort. Among all patients, similar 2-year dysfunction-free catheter survival was noted for normal weight, overweight, and obese patients (log-rank p = 0.79). This was also true across all insertion techniques: open (log-rank p = 0.87), BL (log-rank p = 0.41), AL (log-rank p = 0.43). In the obese cohort, the 2-year dysfunction-free catheter survival was 91.1% in AL, 83.5% in BL, and 65.7% in open (log-rank p = 0.58).

Conclusion

Obesity does not increase complications or shorten dysfunction-free PD catheter survival regardless of the operative technique used. Obesity should not be considered as a relative contraindication to PD catheter placement as it confers similar technique success to normal- and overweight individuals.
Anhänge
Nur mit Berechtigung zugänglich
Literatur
2.
Zurück zum Zitat Kramer HJ, Saranathan A, Luke A, Durazo-Arvizu RA, Guichan C, Hou S, Cooper R (2006) Increasing body mass index and obesity in the incident ESRD population. J Am Soc Nephrol JASN 17:1453–1459. doi:10.1681/ASN.2005111241 CrossRefPubMed Kramer HJ, Saranathan A, Luke A, Durazo-Arvizu RA, Guichan C, Hou S, Cooper R (2006) Increasing body mass index and obesity in the incident ESRD population. J Am Soc Nephrol JASN 17:1453–1459. doi:10.​1681/​ASN.​2005111241 CrossRefPubMed
3.
Zurück zum Zitat United States Renal Data System (2015) USRDS annual data report: epidemiology of kidney disease in the United States United States Renal Data System (2015) USRDS annual data report: epidemiology of kidney disease in the United States
4.
Zurück zum Zitat Hsu C, McCulloch CE, Iribarren C, Darbinian J, Go AS (2006) Body mass index and risk for end-stage renal disease. Ann Intern Med 144:21–28CrossRefPubMed Hsu C, McCulloch CE, Iribarren C, Darbinian J, Go AS (2006) Body mass index and risk for end-stage renal disease. Ann Intern Med 144:21–28CrossRefPubMed
5.
Zurück zum Zitat (1997) NKF-DOQI clinical practice guidelines for peritoneal dialysis adequacy. National Kidney Foundation. Am J Kidney Dis 30:S67–136 (1997) NKF-DOQI clinical practice guidelines for peritoneal dialysis adequacy. National Kidney Foundation. Am J Kidney Dis 30:S67–136
7.
Zurück zum Zitat Nolph KD, Jensen RA, Khanna R, Twardowski ZJ (1994) Weight limitations for weekly urea clearances using various exchange volumes in continuous ambulatory peritoneal dialysis. Perit Dial Int J Int Soc Perit Dial 14:261–264 Nolph KD, Jensen RA, Khanna R, Twardowski ZJ (1994) Weight limitations for weekly urea clearances using various exchange volumes in continuous ambulatory peritoneal dialysis. Perit Dial Int J Int Soc Perit Dial 14:261–264
8.
Zurück zum Zitat McDonald SP, Collins JF, Johnson DW (2003) Obesity is associated with worse peritoneal dialysis outcomes in the Australia and New Zealand patient populations. J Am Soc Nephrol JASN 14:2894–2901CrossRefPubMed McDonald SP, Collins JF, Johnson DW (2003) Obesity is associated with worse peritoneal dialysis outcomes in the Australia and New Zealand patient populations. J Am Soc Nephrol JASN 14:2894–2901CrossRefPubMed
9.
Zurück zum Zitat McDonald SP, Collins JF, Rumpsfeld M, Johnson DW (2004) Obesity is a risk factor for peritonitis in the Australian and New Zealand peritoneal dialysis patient populations. Perit Dial Int J Int Soc Perit Dial 24:340–346 McDonald SP, Collins JF, Rumpsfeld M, Johnson DW (2004) Obesity is a risk factor for peritonitis in the Australian and New Zealand peritoneal dialysis patient populations. Perit Dial Int J Int Soc Perit Dial 24:340–346
10.
Zurück zum Zitat Aslam N, Bernardini J, Fried L, Piraino B (2002) Large body mass index does not predict short-term survival in peritoneal dialysis patients. Perit Dial Int J Int Soc Perit Dial 22:191–196 Aslam N, Bernardini J, Fried L, Piraino B (2002) Large body mass index does not predict short-term survival in peritoneal dialysis patients. Perit Dial Int J Int Soc Perit Dial 22:191–196
11.
Zurück zum Zitat Johnson DW, Herzig KA, Purdie DM, Chang W, Brown AM, Rigby RJ, Campbell SB, Nicol DL, Hawley CM (2000) Is obesity a favorable prognostic factor in peritoneal dialysis patients? Perit Dial Int J Int Soc Perit Dial 20:715–721 Johnson DW, Herzig KA, Purdie DM, Chang W, Brown AM, Rigby RJ, Campbell SB, Nicol DL, Hawley CM (2000) Is obesity a favorable prognostic factor in peritoneal dialysis patients? Perit Dial Int J Int Soc Perit Dial 20:715–721
13.
Zurück zum Zitat Ladhani M, Craig JC, Irving M, Clayton PA, Wong G (2016) Obesity and the risk of cardiovascular and all-cause mortality in chronic kidney disease: a systematic review and meta-analysis. Nephrol Dial Transplant. doi:10.1093/ndt/gfw075 Ladhani M, Craig JC, Irving M, Clayton PA, Wong G (2016) Obesity and the risk of cardiovascular and all-cause mortality in chronic kidney disease: a systematic review and meta-analysis. Nephrol Dial Transplant. doi:10.​1093/​ndt/​gfw075
15.
Zurück zum Zitat Boyle SM, Li Y, Wilson FP, Glickman JD, Feldman HI (2017) Association of alternative approaches to normalizing peritoneal dialysis clearance with mortality and technique failure: a retrospective analysis using the United States renal data system-dialysis morbidity and mortality study, wave 2. Perit Dial Int J Int Soc Perit Dial 37:85–93. doi:10.3747/pdi.2015.00227 CrossRef Boyle SM, Li Y, Wilson FP, Glickman JD, Feldman HI (2017) Association of alternative approaches to normalizing peritoneal dialysis clearance with mortality and technique failure: a retrospective analysis using the United States renal data system-dialysis morbidity and mortality study, wave 2. Perit Dial Int J Int Soc Perit Dial 37:85–93. doi:10.​3747/​pdi.​2015.​00227 CrossRef
16.
Zurück zum Zitat Piraino B, Bernardini J, Centa PK, Johnston JR, Sorkin MI (1991) The effect of body weight on CAPD related infections and catheter loss. Perit Dial Int J Int Soc Perit Dial 11:64–68 Piraino B, Bernardini J, Centa PK, Johnston JR, Sorkin MI (1991) The effect of body weight on CAPD related infections and catheter loss. Perit Dial Int J Int Soc Perit Dial 11:64–68
17.
Zurück zum Zitat Nessim SJ, Komenda P, Rigatto C, Verrelli M, Sood MM (2013) Frequency and microbiology of peritonitis and exit-site infection among obese peritoneal dialysis patients. Perit Dial Int J Int Soc Perit Dial 33:167–174. doi:10.3747/pdi.2011.00244 CrossRef Nessim SJ, Komenda P, Rigatto C, Verrelli M, Sood MM (2013) Frequency and microbiology of peritonitis and exit-site infection among obese peritoneal dialysis patients. Perit Dial Int J Int Soc Perit Dial 33:167–174. doi:10.​3747/​pdi.​2011.​00244 CrossRef
18.
Zurück zum Zitat Krezalek MA, Bonamici N, Lapin B, Carbray J, Velasco J, Denham W, Linn J, Ujiki M, Haggerty SP (2016) Laparoscopic peritoneal dialysis catheter insertion using rectus sheath tunnel and selective omentopexy significantly reduces catheter dysfunction and increases peritoneal dialysis longevity. Surgery 160:924–935. doi:10.1016/j.surg.2016.06.005 CrossRefPubMed Krezalek MA, Bonamici N, Lapin B, Carbray J, Velasco J, Denham W, Linn J, Ujiki M, Haggerty SP (2016) Laparoscopic peritoneal dialysis catheter insertion using rectus sheath tunnel and selective omentopexy significantly reduces catheter dysfunction and increases peritoneal dialysis longevity. Surgery 160:924–935. doi:10.​1016/​j.​surg.​2016.​06.​005 CrossRefPubMed
23.
Zurück zum Zitat Moist LM, Port FK, Orzol SM, Young EW, Ostbye T, Wolfe RA, Hulbert-Shearon T, Jones CA, Bloembergen WE (2000) Predictors of loss of residual renal function among new dialysis patients. J Am Soc Nephrol JASN 11:556–564PubMed Moist LM, Port FK, Orzol SM, Young EW, Ostbye T, Wolfe RA, Hulbert-Shearon T, Jones CA, Bloembergen WE (2000) Predictors of loss of residual renal function among new dialysis patients. J Am Soc Nephrol JASN 11:556–564PubMed
24.
Zurück zum Zitat Tam P (2009) Peritoneal dialysis and preservation of residual renal function. Perit Dial Int J Int Soc Perit Dial 29(Suppl 2):S108–S110 Tam P (2009) Peritoneal dialysis and preservation of residual renal function. Perit Dial Int J Int Soc Perit Dial 29(Suppl 2):S108–S110
26.
Zurück zum Zitat Juergensen E, Wuerth D, Finkelstein SH, Juergensen PH, Bekui A, Finkelstein FO (2006) Hemodialysis and peritoneal dialysis: patients’ assessment of their satisfaction with therapy and the impact of the therapy on their lives. Clin J Am Soc Nephrol CJASN 1:1191–1196. doi:10.2215/CJN.01220406 CrossRefPubMed Juergensen E, Wuerth D, Finkelstein SH, Juergensen PH, Bekui A, Finkelstein FO (2006) Hemodialysis and peritoneal dialysis: patients’ assessment of their satisfaction with therapy and the impact of the therapy on their lives. Clin J Am Soc Nephrol CJASN 1:1191–1196. doi:10.​2215/​CJN.​01220406 CrossRefPubMed
27.
Zurück zum Zitat Fenton SS, Schaubel DE, Desmeules M, Morrison HI, Mao Y, Copleston P, Jeffery JR, Kjellstrand CM (1997) Hemodialysis versus peritoneal dialysis: a comparison of adjusted mortality rates. Am J Kidney Dis 30:334–342CrossRefPubMed Fenton SS, Schaubel DE, Desmeules M, Morrison HI, Mao Y, Copleston P, Jeffery JR, Kjellstrand CM (1997) Hemodialysis versus peritoneal dialysis: a comparison of adjusted mortality rates. Am J Kidney Dis 30:334–342CrossRefPubMed
28.
Zurück zum Zitat Heaf JG, Løkkegaard H, Madsen M (2002) Initial survival advantage of peritoneal dialysis relative to haemodialysis. Nephrol Dial Transplant 17:112–117CrossRefPubMed Heaf JG, Løkkegaard H, Madsen M (2002) Initial survival advantage of peritoneal dialysis relative to haemodialysis. Nephrol Dial Transplant 17:112–117CrossRefPubMed
32.
Zurück zum Zitat Prasad N, Sinha A, Gupta A, Sharma RK, Bhadauria D, Chandra A, Prasad KN, Kaul A (2014) Effect of body mass index on outcomes of peritoneal dialysis patients in India. Perit Dial Int J Int Soc Perit Dial 34:399–408. doi:10.3747/pdi.2013.00056 CrossRef Prasad N, Sinha A, Gupta A, Sharma RK, Bhadauria D, Chandra A, Prasad KN, Kaul A (2014) Effect of body mass index on outcomes of peritoneal dialysis patients in India. Perit Dial Int J Int Soc Perit Dial 34:399–408. doi:10.​3747/​pdi.​2013.​00056 CrossRef
34.
Zurück zum Zitat Singh N, Davidson I, Minhajuddin A, Gieser S, Nurenberg M, Saxena R (2010) Risk factors associated with peritoneal dialysis catheter survival: a 9-year single-center study in 315 patients. J Vasc Access 11:316–322CrossRefPubMedPubMedCentral Singh N, Davidson I, Minhajuddin A, Gieser S, Nurenberg M, Saxena R (2010) Risk factors associated with peritoneal dialysis catheter survival: a 9-year single-center study in 315 patients. J Vasc Access 11:316–322CrossRefPubMedPubMedCentral
35.
Zurück zum Zitat Hsieh Y-P, Chang C-C, Wen Y-K, Chiu P-F, Yang Y (2014) Predictors of peritonitis and the impact of peritonitis on clinical outcomes of continuous ambulatory peritoneal dialysis patients in Taiwan–10 years’ experience in a single center. Perit Dial Int J Int Soc Perit Dial 34:85–94. doi:10.3747/pdi.2012.00075 CrossRef Hsieh Y-P, Chang C-C, Wen Y-K, Chiu P-F, Yang Y (2014) Predictors of peritonitis and the impact of peritonitis on clinical outcomes of continuous ambulatory peritoneal dialysis patients in Taiwan–10 years’ experience in a single center. Perit Dial Int J Int Soc Perit Dial 34:85–94. doi:10.​3747/​pdi.​2012.​00075 CrossRef
Metadaten
Titel
Peritoneal dialysis catheter function and survival are not adversely affected by obesity regardless of the operative technique used
verfasst von
Monika A. Krezalek
Nicolas Bonamici
Kristine Kuchta
Brittany Lapin
JoAnn Carbray
Woody Denham
John Linn
Michael Ujiki
Stephen P. Haggerty
Publikationsdatum
15.09.2017
Verlag
Springer US
Erschienen in
Surgical Endoscopy / Ausgabe 4/2018
Print ISSN: 0930-2794
Elektronische ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-017-5852-y

Weitere Artikel der Ausgabe 4/2018

Surgical Endoscopy 4/2018 Zur Ausgabe

Update Chirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

S3-Leitlinie „Diagnostik und Therapie des Karpaltunnelsyndroms“

Karpaltunnelsyndrom BDC Leitlinien Webinare
CME: 2 Punkte

Das Karpaltunnelsyndrom ist die häufigste Kompressionsneuropathie peripherer Nerven. Obwohl die Anamnese mit dem nächtlichen Einschlafen der Hand (Brachialgia parästhetica nocturna) sehr typisch ist, ist eine klinisch-neurologische Untersuchung und Elektroneurografie in manchen Fällen auch eine Neurosonografie erforderlich. Im Anfangsstadium sind konservative Maßnahmen (Handgelenksschiene, Ergotherapie) empfehlenswert. Bei nicht Ansprechen der konservativen Therapie oder Auftreten von neurologischen Ausfällen ist eine Dekompression des N. medianus am Karpaltunnel indiziert.

Prof. Dr. med. Gregor Antoniadis
Berufsverband der Deutschen Chirurgie e.V.

S2e-Leitlinie „Distale Radiusfraktur“

Radiusfraktur BDC Leitlinien Webinare
CME: 2 Punkte

Das Webinar beschäftigt sich mit Fragen und Antworten zu Diagnostik und Klassifikation sowie Möglichkeiten des Ausschlusses von Zusatzverletzungen. Die Referenten erläutern, welche Frakturen konservativ behandelt werden können und wie. Das Webinar beantwortet die Frage nach aktuellen operativen Therapiekonzepten: Welcher Zugang, welches Osteosynthesematerial? Auf was muss bei der Nachbehandlung der distalen Radiusfraktur geachtet werden?

PD Dr. med. Oliver Pieske
Dr. med. Benjamin Meyknecht
Berufsverband der Deutschen Chirurgie e.V.

S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“

Appendizitis BDC Leitlinien Webinare
CME: 2 Punkte

Inhalte des Webinars zur S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“ sind die Darstellung des Projektes und des Erstellungswegs zur S1-Leitlinie, die Erläuterung der klinischen Relevanz der Klassifikation EAES 2015, die wissenschaftliche Begründung der wichtigsten Empfehlungen und die Darstellung stadiengerechter Therapieoptionen.

Dr. med. Mihailo Andric
Berufsverband der Deutschen Chirurgie e.V.