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Current Cardiology Reports
Erschienen in: Current Cardiology Reports 5/2019

01.05.2019 | Nuclear Cardiology (V Dilsizian, Section Editor)

PET/CT for Diagnosis and Management of Large-Vessel Vasculitis

verfasst von: Matthieu Pelletier-Galarneau, Terrence D. Ruddy

Erschienen in: Current Cardiology Reports | Ausgabe 5/2019

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Abstract

Purpose of Review

This review aims to discuss the use of fluorodeoxyglucose (FDG) positron emission tomography (PET/CT) for diagnosis and management of patients with large-vessel vasculitis (LVV).

Recent Findings

Incidence of LVV is likely underestimated, in part due to its non-specific symptoms. Nevertheless, early diagnosis of LVV is essential to initiate timely therapy in order to prevent vascular complications, such as stenoses and aneurysms. FDG PET/CT imaging has the ability to detect LVV during the acute phase, prior to edema and other vascular structural changes, with its high sensitivity for inflammatory activity. FDG PET/CT was shown to be a powerful prognostic marker by allowing identification of patients at risk of vascular complications. Additionally, preliminary data support the use of FDG PET/CT to follow therapy efficacy.

Summary

FDG PET/CT allows early detection of inflammation, before morphological and irreversible vascular changes can be observed, allowing prompt diagnosis and treatment of LVV.
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Metadaten
Titel
PET/CT for Diagnosis and Management of Large-Vessel Vasculitis
verfasst von
Matthieu Pelletier-Galarneau
Terrence D. Ruddy
Publikationsdatum
01.05.2019
Verlag
Springer US
Erschienen in
Current Cardiology Reports / Ausgabe 5/2019
Print ISSN: 1523-3782
Elektronische ISSN: 1534-3170
DOI
https://doi.org/10.1007/s11886-019-1122-z

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