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European Journal of Nuclear Medicine and Molecular Imaging

Erschienen in:

28.01.2022 | Image of the Month

PET imaging of metastatic paraganglioma using novel 3-[¹⁸F]fluoro-para-hydroxyphenethylguanidine (3-[¹⁸F]pHPG) radiotracer

verfasst von: Ka Kit Wong, Tobias Else, Benjamin L. Viglianti, Allen F. Brooks, Kirk A. Frey, David M. Raffel

Erschienen in: European Journal of Nuclear Medicine and Molecular Imaging | Ausgabe 6/2022

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Excerpt

3-[¹⁸F]Fluoro-para-hydroxyphenethylguanidine (3-[¹⁸F]pHPG) is a substrate of the norepinephrine transporter (NET) and the vesicular monoamine transporter isoform 2 (VMAT2) that localizes in presynaptic sympathetic nerve terminals in organs with high sympathetic innervation (e.g., heart, adrenal glands) in normal subjects [1], and demonstrates cardiac denervation in patients with cardiomyopathy [2]. …

Raffel DM, Jung YW, Koeppe RA, Jang KS, Gu G, Scott PJH, et al. First-in-human studies of [¹⁸F] fluorohydroxyphenethylguanidines. Circ Cardiovasc Imaging. 2018;11: e007965. https://doi.org/10.1161/circimaging.118.007965.CrossRefPubMedPubMedCentral

Raffel DM, Crawford TC, Jung YW, Koeppe RA, Gu G, Rothley J, et al. Quantifying cardiac sympathetic denervation: first studies of ¹⁸F-fluorohydroxyphenethylguanidines in cardiomyopathy patients. Eur J Nucl Med Mol Imaging. 2021. https://doi.org/10.1007/s00259-021-05517-7.CrossRefPubMed

Titel: PET imaging of metastatic paraganglioma using novel 3-[18F]fluoro-para-hydroxyphenethylguanidine (3-[18F]pHPG) radiotracer
verfasst von: Ka Kit Wong
Tobias Else
Benjamin L. Viglianti
Allen F. Brooks
Kirk A. Frey
David M. Raffel
Publikationsdatum: 28.01.2022
Verlag: Springer Berlin Heidelberg
Erschienen in: European Journal of Nuclear Medicine and Molecular Imaging / Ausgabe 6/2022
Print ISSN: 1619-7070
Elektronische ISSN: 1619-7089
DOI: https://doi.org/10.1007/s00259-021-05639-y

Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

PET imaging of metastatic paraganglioma using novel 3-[¹⁸F]fluoro-para-hydroxyphenethylguanidine (3-[¹⁸F]pHPG) radiotracer

Excerpt

Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

Excerpt

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