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06.11.2019 | Pharmacotherapies and Drug Development/Agents (ES Rovner, Section Editor)

Pharmacotherapy for Interstitial Cystitis/Bladder Pain Syndrome

verfasst von: Alyssa Greiman, Lindsey Cox

Erschienen in: Current Bladder Dysfunction Reports

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Abstract

Purpose of Review

Current literature regarding pharmacotherapy treatment strategies available for the management of interstitial cystitis/bladder pain syndrome (IC/BPS) will be addressed including oral, transdermal, and intravesical therapies. Pharmacotherapies with emerging data will be addressed, but the focus is on those treatments described by the AUA guidelines for IC/BPS.

Recent Findings

While multiple pharmacotherapy options for the management of IC/BPS exist, the evidence for most medical therapies is not strong and frequently yields mixed results. It has been over two decades since a new medication has gained FDA approval for the treatment of IC/BPS. This has prompted clinicians to reassess the approach to evaluating patients with IC/BPS, leading to the advent of phenotype-directed multimodal therapy.

Summary

Though national and international guidelines recommend a step-wise treatment algorithm beginning with the most conservative treatment options, the evidence for most therapies is mixed. Furthermore, recent randomized controlled trials of promising treatment options have yielded negative results, highlighting the importance of phenotype-directed classification to aid in the current management of IC/BPS and to allow for better research trial designs.

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Titel: Pharmacotherapy for Interstitial Cystitis/Bladder Pain Syndrome
verfasst von: Alyssa Greiman
Lindsey Cox
Publikationsdatum: 06.11.2019
Verlag: Springer US
Erschienen in: Current Bladder Dysfunction Reports
Print ISSN: 1931-7212
Elektronische ISSN: 1931-7220
DOI: https://doi.org/10.1007/s11884-019-00540-9

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Springer Medizin

Pharmacotherapy for Interstitial Cystitis/Bladder Pain Syndrome

Abstract

Purpose of Review

Recent Findings

Summary

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Springer Medizin

Abstract

Purpose of Review

Recent Findings

Summary

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Neu im Fachgebiet Urologie

Adjuvante Immuntherapie verlängert Leben bei RCC

Bei Senioren mit Prostatakarzinom auf Anämie achten!

Stufenschema weist Prostatakarzinom zuverlässig nach

Harnwegsinfektprophylaxe: Es geht auch ohne Antibiotika

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