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Current Allergy and Asthma Reports
Erschienen in: Current Allergy and Asthma Reports 7/2020

01.07.2020 | Rhinitis, Conjunctivitis, and Sinusitis (J Oppenheimer and J Corrent, Section Editors)

Phenotypes in Chronic Rhinosinusitis

verfasst von: Justin P. McCormick, Harrison M. Thompson, Do-Yeon Cho, Bradford A. Woodworth, Jessica W. Grayson

Erschienen in: Current Allergy and Asthma Reports | Ausgabe 7/2020

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Abstract

Purpose of Review

Chronic rhinosinusitis (CRS) is a heterogenous disease process affecting a significant proportion of the population and impacting quality of life and productivity. Historically, CRS has been classified broadly into CRS with nasal polyps (CRSwNP) and CRS without nasal polyps (CRSsNP). Increased understanding regarding unique presentations of CRS subsets and their underlying inflammatory profiles has led to a new system for classifying CRS phenotypes.

Recent Findings

Consideration of CRS phenotypes has traditionally been a key factor in determining treatment paradigms. Under a new phenotype classification system, physical findings will continue to drive treatment decisions, but with more precision.

Summary

Recent rapidly accumulated knowledge indicates that the broad categorization of CRSwNP or CRSsNP is no longer clinically useful. Reorganization of CRS phenotypes and their underlying endotypes will lead to more targeted and efficacious therapy.
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Metadaten
Titel
Phenotypes in Chronic Rhinosinusitis
verfasst von
Justin P. McCormick
Harrison M. Thompson
Do-Yeon Cho
Bradford A. Woodworth
Jessica W. Grayson
Publikationsdatum
01.07.2020
Verlag
Springer US
Erschienen in
Current Allergy and Asthma Reports / Ausgabe 7/2020
Print ISSN: 1529-7322
Elektronische ISSN: 1534-6315
DOI
https://doi.org/10.1007/s11882-020-00916-6

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