Pick your prior: scepticism about sceptical prior beliefs

verfasst von: Harm-Jan de Grooth, Paul Elbers

Erschienen in: Intensive Care Medicine | Ausgabe 3/2022

Excerpt

It is with initial curiosity followed by admiration but then significant confusion that we studied the recent secondary Bayesian analysis of the COVID STEROID 2 trial comparing dexamethasone 12 mg versus 6 mg for patients with coronavirus disease 2019 (COVID-19) and severe hypoxemia, as well as the accompanying optimistic tweets by the journal and the authors [ 1]. …

Granholm A, Munch MW, Myatra SN et al (2021) Dexamethasone 12 mg versus 6 mg for patients with COVID-19 and severe hypoxaemia: a pre-planned, secondary Bayesian analysis of the COVID STEROID 2 trial. Intensive Care Med. https://doi.org/10.1007/s00134-021-06573-1 CrossRefPubMedPubMedCentral

Young PJ, Nickson CP, Perner A (2020) When should clinicians act on non-statistically significant results from clinical trials? JAMA 323:2256. https://doi.org/10.1001/jama.2020.3508 CrossRefPubMed

Titel: Pick your prior: scepticism about sceptical prior beliefs
verfasst von: Harm-Jan de Grooth
Paul Elbers
Publikationsdatum: 17.12.2021
Verlag: Springer Berlin Heidelberg
Erschienen in: Intensive Care Medicine / Ausgabe 3/2022
Print ISSN: 0342-4642
Elektronische ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-021-06602-z