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The official publication of the Pituitary Society and the Growth Hormone Research Society

Pituitary OnlineFirst articles


Granular cell tumors of the sellar region: what should be done after subtotal resection? A systematic review

Granular cell tumors (GCT) (a.k.a. choristoma, granular cell myoblastoma or granular cell pituicytoma) were initially described by Boyce and Beadles in 1893 as a distinct neoplastic pathology in the pituitary gland [ 1 ]. Several decades later …


The 5-factor modified frailty index predicts health burden following surgery for pituitary adenomas

Pituitary tumors are the most common skull base tumors and can present with a variety of symptoms due to mass effect or hormonal abnormalities [ 1 ]. For most subtypes, neurosurgical resection remains the mainstay of care. Endoscopic endonasal …


Secondary pituitary hormonal dysfunction patterns: tumor size and subtype matter

Secondary hormonal deficiency (SHD) occurs in 20–75% patients presenting with sellar masses (SM) [ 1 , 2 ]. Although the underlying mechanism of SHD is not fully understood, it is thought to be due in part to the increased intrasellar pressure …

20.07.2020 Open Access

The importance of specialized sleep investigations in children with a suprasellar tumor

Due to increased survival rates for children with a CNS tumor, the late effects of the tumor and its treatment are becoming more visible and more important [ 1 ]. Childhood brain tumor survivors (CBTS) often report a low quality of life and an …


Outcomes of pituitary surgery for Cushing’s disease: a systematic review and meta-analysis

Cushing’s disease (CD) is an uncommon disorder of hypercortisolism caused by the excess secretion of adrenocorticotropic hormone (ACTH) by a pituitary corticotroph adenoma. Prolonged exposure to endogenous glucocorticoids in CD carries significant …

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