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Pituitary OnlineFirst articles


Shall we be less aggressive in pituitary surgery in the elderly?


A novel diagnostic method for pituitary adenoma based on magnetic resonance imaging using a convolutional neural network

Pituitary adenoma is a diverse group of neoplasms arising from adenohypophysial cells in the sella turcica [ 1 ]. According to the recent epidemiological investigation, pituitary adenoma occurs mostly in young adults at the age of 30–35 and has …


Growth hormone therapy in adults with growth hormone deficiency: a critical assessment of the literature

The development of biosynthetic growth hormone (GH) has dramatically changed the lives of thousands of children with growth hormone deficiency (GHD) and short stature by promoting their statural growth. The widespread availability of biosynthetic …


Expression patterns of ERα66 and its novel variant isoform ERα36 in lactotroph pituitary adenomas and associations with clinicopathological characteristics

Prolactin-producing adenomas are the most common subtype of hormone-secreting pituitary tumors. The prevalence of prolactinoma ranges from 10 to 50 per 100,000 [ 1 ]. According to the new 2017 World Health Organization (WHO) classification of …


Effects of octreotide on autophagy markers and cell viability markers related to metabolic activity in rat pituitary tumor cells

Autophagy is an evolutionary conserved mechanism for the lysosome-mediated degradation of cellular components in the cytoplasm and a cell survival mechanism in starving cells. Actually, autophagy has also been associated with programmed type II …

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