Skip to main content
main-content

01.12.2012 | Research | Ausgabe 1/2012 Open Access

Malaria Journal 1/2012

Plasmodium vivax malaria in Mali: a study from three different regions

Zeitschrift:
Malaria Journal > Ausgabe 1/2012
Autoren:
Maria Bernabeu, Gloria P Gomez-Perez, Sibiri Sissoko, Mohamed B Niambélé, Allassane Ag Haibala, Ariadna Sanz, Mahamadou A Théra, Carmen Fernandez-Becerra, Klénon Traoré, Pedro L Alonso, Quique Bassat, Hernando A del Portillo, Ogobara Doumbo
Wichtige Hinweise

Electronic supplementary material

The online version of this article (doi:10.​1186/​1475-2875-11-405) contains supplementary material, which is available to authorized users.
Maria Bernabeu, Gloria P Gomez-Perez contributed equally to this work.

Competing interests

The authors declare that they have no competing interests.

Authors’ contributions

MB and GGP performed the experiments. MB, GGP, CFB, HAP analysed data. AS, MTHA managed the project. SS, AH, MBN, KT, MTA did the samples collection. QB, PLA, HAP and OD conceived and designed the study. HAP, QB, MB, GGP and OD wrote the paper. All authors read and approved the final manuscript.

Abstract

Background

Plasmodium vivax has traditionally been considered virtually absent from Western and Central Africa, due to the absence of the Duffy blood group in most of the population living in these areas. Recent reports, however, suggest the circulation of P. vivax in sub-Saharan Africa.

Methods

Giemsa/Field-stained smears from febrile patients recruited in five different cities (Goundam, Tombouctou, Gao, Bourem and Kidal) pertaining to three regions from Northern Mali were examined. Nested-PCR and DNA sequence analyses of selected samples were performed to fully confirm the presence of P. vivax infections.

Results

Results demonstrated the presence of P. vivax infections in close to 30% of the cases as detected by Giemsa/Field-stained smears and nested-PCR and DNA-sequence analyses of selected samples unequivocally confirmed the presence of P. vivax.

Conclusions

The diagnostics of this human malaria parasite should be taken into account in the context of malaria control and elimination efforts, not only in Mali, but also in sub-Saharan Africa.
Zusatzmaterial
Additional file 1: Vivax malaria in Mali. Additional illustrative images of Giemsa-stained smear P. vivax positive samples from different regions. (PDF 1 MB)
12936_2012_2602_MOESM1_ESM.pdf
Additional file 2: Clustal W Alignment of SSU RNA sequences from different Plasmoidum spp. Hyphens indicate gaps. Colour scale from minimal consensus (dark blue) to exact consensus (red). (PDF 3 MB)
12936_2012_2602_MOESM2_ESM.pdf
Authors’ original file for figure 1
12936_2012_2602_MOESM3_ESM.pdf
Authors’ original file for figure 2
12936_2012_2602_MOESM4_ESM.pdf
Authors’ original file for figure 3
12936_2012_2602_MOESM5_ESM.pdf
Literatur
Über diesen Artikel

Weitere Artikel der Ausgabe 1/2012

Malaria Journal 1/2012 Zur Ausgabe

Neu im Fachgebiet Innere Medizin

Meistgelesene Bücher aus der Inneren Medizin

2017 | Buch

Rheumatologie aus der Praxis

Entzündliche Gelenkerkrankungen – mit Fallbeispielen

Dieses Fachbuch macht mit den wichtigsten chronisch entzündlichen Gelenk- und Wirbelsäulenerkrankungen vertraut. Anhand von über 40 instruktiven Fallbeispielen werden anschaulich diagnostisches Vorgehen, therapeutisches Ansprechen und der Verlauf …

Herausgeber:
Rudolf Puchner

2016 | Buch

Ambulant erworbene Pneumonie

Was, wann, warum – Dieses Buch bietet differenzierte Diagnostik und Therapie der ambulant erworbenen Pneumonie zur sofortigen sicheren Anwendung. Entsprechend der neuesten Studien und Leitlinien aller wichtigen Fachgesellschaften.

Herausgeber:
Santiago Ewig

Mail Icon II Newsletter

Bestellen Sie unseren kostenlosen Newsletter Update Innere Medizin und bleiben Sie gut informiert – ganz bequem per eMail.

© Springer Medizin 

Bildnachweise