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Erschienen in: International Journal of Legal Medicine 2/2020

28.02.2019 | Population Data

Population genetic data of 30 insertion–deletion markers in Punjabi population of Pakistan

verfasst von: Muhammad Shahzad, Manzoor Hussain, Muhammad Shafique, Rukhsana Perveen, Nadeem Sheikh

Erschienen in: International Journal of Legal Medicine | Ausgabe 2/2020

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Abstract

Insertion–deletion polymorphism (Indels) is valuable diallelic markers for forensic as well as parentage analysis. The Investigator DIPplex Kit (Qiagen) contains thirty autosomal Indels markers along with amelogenin. These thirty markers were tested in the Pakistani Punjabi Population but no significant deviations were observed from Hardy–Weinberg equilibrium rule expectations (Bonferroni corrected) except HLD58, HLD56, HLD99, and HLD40. The mean expected and observed heterozygosity was found 0.4701 and 0.4667 respectively; combined matching probability was computed as 7.31867 × 10−13. However, the use of the 30 Indels markers proved to be a good supplementary tool in forensic casework, particularly when evidence sample is highly degraded. The significant genetic differences were also observed between the Punjabi and other populations of the world.
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Metadaten
Titel
Population genetic data of 30 insertion–deletion markers in Punjabi population of Pakistan
verfasst von
Muhammad Shahzad
Manzoor Hussain
Muhammad Shafique
Rukhsana Perveen
Nadeem Sheikh
Publikationsdatum
28.02.2019
Verlag
Springer Berlin Heidelberg
Erschienen in
International Journal of Legal Medicine / Ausgabe 2/2020
Print ISSN: 0937-9827
Elektronische ISSN: 1437-1596
DOI
https://doi.org/10.1007/s00414-019-02029-w

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