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12.08.2016 | Population Data | Ausgabe 6/2016

International Journal of Legal Medicine 6/2016

Population genetics of 23 Y-STR loci in the Mongolian minority population in Inner Mongolia of China

Zeitschrift:
International Journal of Legal Medicine > Ausgabe 6/2016
Autoren:
Tianzhen Gao, Libing Yun, Shuang Gao, Yan Gu, Wang He, Haibo Luo, Yiping Hou
Wichtige Hinweise

Electronic supplementary material

The online version of this article (doi:10.​1007/​s00414-016-1433-1) contains supplementary material, which is available to authorized users.
Tianzhen Gao and Libing Yun contributed equally to this work. Libing Yun should be considered co-first author.

Abstract

In this study, 23 Y chromosomal STRs (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385a, DYS385b, DYS438, DYS439, DYS437, DYS448, DYS456, DYS458, DYS635, YGATAH4, DYS576, DYS481, DYS549, DYS533, DYS570, and DYS643) were investigated in 258 unrelated individuals of Mongolian descent living in the Inner Mongolia Autonomous Region. A total of 233 different haplotypes were found, and 209 of them were unique. Haplotype diversity was 0.9992 and gene diversity ranged from 0.4840 (DYS391) to 0.9679 (DYS385ab). Both R st pairwise analysis and multidimensional scaling plot showed that the genetic structure of the Mongolian population was significantly different from some Chinese ethnic groups and neighboring populations. It is notable that there were null features existing at DYS448 as observed by the PowerPlex® Y23 System, which could be also obtained by sequencing in the Tibetan population.

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Zusatzmaterial
Supplementary Fig. 1 The location of our sample collection in Inner Mongolia (red colour) on a map of China. (DOCX 705 kb)
414_2016_1433_MOESM1_ESM.docx
Supplementary Fig. 2 The MDS graphs of 16 populations analysed in this study. The plot showing distances based on Rst values calculated with online tool at YHRD.org. (DOCX 187 kb)
414_2016_1433_MOESM2_ESM.docx
Supplementary Fig. 3 Electropherograms. (a) Null alleles detected at locus DYS448 in seven individuals with the PowerPlex® Y23 kit. (b) Null alleles detected at locus DYS448 in these seven individuals with the AGCU Database Y24 STR genotyping kit. (DOCX 539 kb)
414_2016_1433_MOESM3_ESM.docx
Supplementary Table 1 23 Y-STR haplotypes of Mongolians from Inner Mongolia Autonomous Region. (XLS 89 kb)
414_2016_1433_MOESM4_ESM.xls
Supplementary Table 2 Allele frequencies and gene diversities of 23 Y-STR loci in 258 unrelated Mongolians from Inner Mongolia Autonomous Region. (XLS 53 kb)
414_2016_1433_MOESM5_ESM.xls
Supplementary Table 3 Pairwise R st values (below diagonal) and p values (above diagonal) calculated for the Mongolians and some other Chinese groups and neighboring populations. (XLSX 12 kb)
414_2016_1433_MOESM6_ESM.xlsx
Supplementary Table 4 Sequence in the relevant flanking and repeat region of the DYS448 locus for null alleles (DOC 30 kb)
414_2016_1433_MOESM7_ESM.doc
Literatur
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