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Erschienen in: Heart and Vessels 11/2022

14.05.2022 | Original Article

Possibility of steroid therapy without pacemaker implantation in patients with sarcoidosis presenting atrioventricular block

verfasst von: Kenji Yodogawa, Yuhi Fujimoto, Kanako Hagiwara, Eiichiro Oka, Hiroshi Hayashi, Hiroshige Murata, Teppei Yamamoto, Yu-ki Iwasaki, Wataru Shimizu

Erschienen in: Heart and Vessels | Ausgabe 11/2022

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Abstract

Atrioventricular Block (AVB) is one of the common manifestations in cardiac sarcoidosis (CS). Although pacemaker implantation is generally recommended in patients with CS complicated by symptomatic AVB, some case reports have shown that they can be managed by steroid therapy without pacemaker implantation. The aim of this study was to evaluate the feasibility and effectiveness of steroid therapy without pacemaker implantation in patients with CS complicated by symptomatic AVB. We performed medical record review of consecutive ten CS patients who admitted Nippon Medical School Hospital for symptomatic second or third degree AVB between April 2015 and March 2021. Of the studied population, steroid therapy before pacemaker implantation was feasible in three patients with second degree AVB. Two of them showed subsequent recovery of atrioventricular conduction to 1:1, and they were managed by steroid therapy without pacemaker. The remaining one patient showed no improvement of atrioventricular conduction and required pacemaker implantation. Seven patients with third degree AVB required device implantation (pacemaker; n = 7, cardiac resynchronization therapy defibrillator; n = 1) before steroid therapy mainly because of hemodynamic instability. Steroid therapy without pacemaker implantation might be feasible, and possibly be effective in patients with CS presenting second degree AVB. However, the feasibility is limited in patients with third degree AVB.
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Metadaten
Titel
Possibility of steroid therapy without pacemaker implantation in patients with sarcoidosis presenting atrioventricular block
verfasst von
Kenji Yodogawa
Yuhi Fujimoto
Kanako Hagiwara
Eiichiro Oka
Hiroshi Hayashi
Hiroshige Murata
Teppei Yamamoto
Yu-ki Iwasaki
Wataru Shimizu
Publikationsdatum
14.05.2022
Verlag
Springer Japan
Erschienen in
Heart and Vessels / Ausgabe 11/2022
Print ISSN: 0910-8327
Elektronische ISSN: 1615-2573
DOI
https://doi.org/10.1007/s00380-022-02092-1

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