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Erschienen in: Pediatric Cardiology 1/2013

01.01.2013 | Original Article

Postnatal Outcome in Patients With Fetal Tachycardia

verfasst von: Shreya Moodley, Shubhayan Sanatani, James E. Potts, George G. S. Sandor

Erschienen in: Pediatric Cardiology | Ausgabe 1/2013

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Abstract

The diagnosis and management of prenatal tachyarrhythmias is well established; however, the postnatal course and outcomes are not. The purpose of our study was to review the natural history of patients with fetal tachycardia, determine the incidence of postnatal arrhythmias, and determine whether there are factors to predict which fetuses will develop postnatal arrhythmias. A retrospective chart review of patients with fetal tachyarrhythmias investigated at British Columbia Children’s and Women’s Hospitals between 1983 and 2010 was conducted. Sixty-nine mother–fetus pairs were eligible for the study. Fifty-two had fetal supraventricular tachycardia, and 17 had fetal atrial flutter. Conversion to sinus rhythm occurred prenatally in 52 % of patients. Postnatal arrhythmia occurred in two thirds of patients, with 82 % of those cases occurring within the first 48 h of life. Hydrops fetalis, female sex, and lack of conversion to sinus rhythm was predictive of postnatal arrhythmia (P = 0.01, P = 0.01, and P = 0.001, respectively). Conversion to sinus rhythm prenatally did not predict postnatal arrhythmia. Median duration of treatment was 9 months. Two postnatal deaths of unknown etiology occurred. Two thirds of all patients with prenatal tachycardia will develop postnatal arrhythmia. Prenatal factors that predict postnatal arrhythmia include hydrops, sex, and whether or not conversion to sinus rhythm occurred prenatally. The majority of patients with postnatal arrhythmia present within 48 h of life, which has clinical implications for monitoring. Postnatal outcome is generally very good with most patients being weaned off medication in 6–12 months.
Literatur
1.
Zurück zum Zitat Api O, Carvalho JS (2008) Fetal dysrhythmias. Best practice and research. Clin Obstet Gynaecol 22:31–48 Api O, Carvalho JS (2008) Fetal dysrhythmias. Best practice and research. Clin Obstet Gynaecol 22:31–48
2.
Zurück zum Zitat Bauersfeld U, Pfammatter JP, Jaeggi E (2001) Treatment of supraventricular tachycardias in the new millenium—drugs or radio-frequency catheter ablation? Eur J Pediatr 160:1–9PubMedCrossRef Bauersfeld U, Pfammatter JP, Jaeggi E (2001) Treatment of supraventricular tachycardias in the new millenium—drugs or radio-frequency catheter ablation? Eur J Pediatr 160:1–9PubMedCrossRef
3.
Zurück zum Zitat Boldt T, Eronen M, Andersson S (2003) Long-term outcome in fetuses with cardiac arrhythmias. Obstet Gynecol 102:1372–1379PubMedCrossRef Boldt T, Eronen M, Andersson S (2003) Long-term outcome in fetuses with cardiac arrhythmias. Obstet Gynecol 102:1372–1379PubMedCrossRef
4.
Zurück zum Zitat Cornette J, Ten Harkel ADJ, Steegers EAP (2009) Fetal dilated cardiomyopathy caused by PJRT. Ultrasound Obstet Gynecol 33:595–598PubMedCrossRef Cornette J, Ten Harkel ADJ, Steegers EAP (2009) Fetal dilated cardiomyopathy caused by PJRT. Ultrasound Obstet Gynecol 33:595–598PubMedCrossRef
5.
Zurück zum Zitat D’Alto M, Russo MG, Paladini D, Di Salvo G, Romeo E, Ricci C et al (2008) The challenge of fetal dysrhythmias: echocardiographic diagnosis and clinical management. J Cardiovasc Med 9:153–160CrossRef D’Alto M, Russo MG, Paladini D, Di Salvo G, Romeo E, Ricci C et al (2008) The challenge of fetal dysrhythmias: echocardiographic diagnosis and clinical management. J Cardiovasc Med 9:153–160CrossRef
6.
7.
Zurück zum Zitat Hahurij ND, Gittenberger-De Groot AC, Kolditz DP, Bokenkamp R, Schalij MJ, Poelmann RE et al (2008) Accessory atrioventricular myocardial connections in the developing human heart: relevance for perinatal SVT. Circulation 117:2850–2858PubMedCrossRef Hahurij ND, Gittenberger-De Groot AC, Kolditz DP, Bokenkamp R, Schalij MJ, Poelmann RE et al (2008) Accessory atrioventricular myocardial connections in the developing human heart: relevance for perinatal SVT. Circulation 117:2850–2858PubMedCrossRef
8.
9.
Zurück zum Zitat Jaeggi E, Fouron JC, Drblik SP (1998) Fetal atrial flutter: diagnosis, clinical features, treatment, and outcome. J Pediatr 132:335–339PubMedCrossRef Jaeggi E, Fouron JC, Drblik SP (1998) Fetal atrial flutter: diagnosis, clinical features, treatment, and outcome. J Pediatr 132:335–339PubMedCrossRef
10.
Zurück zum Zitat Jaeggi ET, Carvalho JS, De Groot E, Api O, Clur S-AB, Rammeloo L et al (2011) Comparison of transplacental treatment of fetal supraventricular tachyarrhythmias with digoxin, flecainide, and sotalol: results of a nonrandomized center study. Circulation 124:1474–1754CrossRef Jaeggi ET, Carvalho JS, De Groot E, Api O, Clur S-AB, Rammeloo L et al (2011) Comparison of transplacental treatment of fetal supraventricular tachyarrhythmias with digoxin, flecainide, and sotalol: results of a nonrandomized center study. Circulation 124:1474–1754CrossRef
11.
Zurück zum Zitat Krapp M, Kohl T, Simpon JM, Sharland GK, Katalinic A, Gembruch U (2003) Review of diagnosis, treatment, and outcome of fetal atrial flutter compared with SVT. Heart 89:913–917PubMedCrossRef Krapp M, Kohl T, Simpon JM, Sharland GK, Katalinic A, Gembruch U (2003) Review of diagnosis, treatment, and outcome of fetal atrial flutter compared with SVT. Heart 89:913–917PubMedCrossRef
12.
Zurück zum Zitat Lulic Jurjevic R, Podnar T, Vesel S (2009) Diagnosis, clinical features, management, and post-natal follow-up of fetal tachycardias. Cardiol Young 19:486–493PubMedCrossRef Lulic Jurjevic R, Podnar T, Vesel S (2009) Diagnosis, clinical features, management, and post-natal follow-up of fetal tachycardias. Cardiol Young 19:486–493PubMedCrossRef
13.
Zurück zum Zitat Maeno Y, Hirose A, Kanbe T, Hori D (2009) Fetal arrhythmia: prenatal diagnosis and perinatal management. J Obstet Gynaecol Res 35:623–629PubMedCrossRef Maeno Y, Hirose A, Kanbe T, Hori D (2009) Fetal arrhythmia: prenatal diagnosis and perinatal management. J Obstet Gynaecol Res 35:623–629PubMedCrossRef
14.
Zurück zum Zitat Mongiovi M, Pipitone S (2008) Supraventricular tachycardia in fetus: how can we treat? Curr Pharm Des 14:736–742PubMedCrossRef Mongiovi M, Pipitone S (2008) Supraventricular tachycardia in fetus: how can we treat? Curr Pharm Des 14:736–742PubMedCrossRef
15.
Zurück zum Zitat Oudijk MA, Michon MM, Kleinman CS, Kapusta L, Stoutenbeek P, Visser GH et al (2000) Sotalol in the treatment of fetal dysrhythmias. Circulation 101:2721–2726PubMedCrossRef Oudijk MA, Michon MM, Kleinman CS, Kapusta L, Stoutenbeek P, Visser GH et al (2000) Sotalol in the treatment of fetal dysrhythmias. Circulation 101:2721–2726PubMedCrossRef
16.
Zurück zum Zitat Pezard PG, Boussion F, Sentilhes L, Lepinard C, Couvreur M-H, Victor J et al (2008) Fetal tachycardia: a role for amiodarone as first- or second-line therapy? Arch Cardiovasc Dis 101:619–627PubMedCrossRef Pezard PG, Boussion F, Sentilhes L, Lepinard C, Couvreur M-H, Victor J et al (2008) Fetal tachycardia: a role for amiodarone as first- or second-line therapy? Arch Cardiovasc Dis 101:619–627PubMedCrossRef
17.
Zurück zum Zitat Simpson LL (2000) Fetal supraventricular tachycardias: diagnosis and management. Semin Perinatol 24:360–372PubMedCrossRef Simpson LL (2000) Fetal supraventricular tachycardias: diagnosis and management. Semin Perinatol 24:360–372PubMedCrossRef
19.
Zurück zum Zitat Simpson JM, Sharland GK (1998) Fetal tachycardia: management and outcome of 127 consecutive cases. Heart 79:576–581PubMed Simpson JM, Sharland GK (1998) Fetal tachycardia: management and outcome of 127 consecutive cases. Heart 79:576–581PubMed
20.
Zurück zum Zitat Singh GK (2004) Management of fetal tachyarrhythmias. Curr Treat Options Cardiovasc Med 6:399–406PubMedCrossRef Singh GK (2004) Management of fetal tachyarrhythmias. Curr Treat Options Cardiovasc Med 6:399–406PubMedCrossRef
21.
Zurück zum Zitat Skinner JR, Sharland G (2008) Detection and management of life-threatening arrhythmias in the perinatal period. Early Hum Dev 84:161–172PubMedCrossRef Skinner JR, Sharland G (2008) Detection and management of life-threatening arrhythmias in the perinatal period. Early Hum Dev 84:161–172PubMedCrossRef
22.
Zurück zum Zitat Srinivasan S, Strasburger J (2008) Overview of fetal arrhythmias. Curr Opin Pediatr 20:522–531PubMedCrossRef Srinivasan S, Strasburger J (2008) Overview of fetal arrhythmias. Curr Opin Pediatr 20:522–531PubMedCrossRef
23.
24.
Zurück zum Zitat Trappe H-J (2006) Acute therapy of maternal and fetal arrhythmias during pregnancy. J Intensive Care Med 21:305PubMedCrossRef Trappe H-J (2006) Acute therapy of maternal and fetal arrhythmias during pregnancy. J Intensive Care Med 21:305PubMedCrossRef
25.
Zurück zum Zitat Vaksmann G, D’ Hoinne C, Lucet V, Guillaumont S, Lupoglazoff J-M, Chantepie A et al (2006) Permanent junctional reciprocating tachycardia in children: a multicentre study on clinical profile and outcome. Heart 92:101–104PubMedCrossRef Vaksmann G, D’ Hoinne C, Lucet V, Guillaumont S, Lupoglazoff J-M, Chantepie A et al (2006) Permanent junctional reciprocating tachycardia in children: a multicentre study on clinical profile and outcome. Heart 92:101–104PubMedCrossRef
26.
Zurück zum Zitat van Engelen AD, Weijtens O, Brenner JI, Kleinman CS, Copel JA, Stoutenbeek P et al (1994) Management, outcome and follow-up of fetal tachycardia. J Am Coll Cardiol 24:1371–1375PubMedCrossRef van Engelen AD, Weijtens O, Brenner JI, Kleinman CS, Copel JA, Stoutenbeek P et al (1994) Management, outcome and follow-up of fetal tachycardia. J Am Coll Cardiol 24:1371–1375PubMedCrossRef
27.
Zurück zum Zitat Vergani P, Mariani E, Ciriello E, Locatelli A, Strobelt N, Galli M et al (2005) Fetal arrhythmias: natural history and management. Ultrasound Med Biol 31:1–6PubMedCrossRef Vergani P, Mariani E, Ciriello E, Locatelli A, Strobelt N, Galli M et al (2005) Fetal arrhythmias: natural history and management. Ultrasound Med Biol 31:1–6PubMedCrossRef
28.
Zurück zum Zitat Wren C (2006) Cardiac arrhythmias in the fetus and newborn. Semin Fetal Neonatal Med 11:182–190PubMedCrossRef Wren C (2006) Cardiac arrhythmias in the fetus and newborn. Semin Fetal Neonatal Med 11:182–190PubMedCrossRef
Metadaten
Titel
Postnatal Outcome in Patients With Fetal Tachycardia
verfasst von
Shreya Moodley
Shubhayan Sanatani
James E. Potts
George G. S. Sandor
Publikationsdatum
01.01.2013
Verlag
Springer-Verlag
Erschienen in
Pediatric Cardiology / Ausgabe 1/2013
Print ISSN: 0172-0643
Elektronische ISSN: 1432-1971
DOI
https://doi.org/10.1007/s00246-012-0392-7

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